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Egas Moniz Bandeira 한양대학교 아태지역연구센터 2020 Journal of Eurasian Studies Vol.11 No.1
The article examines the relationship between the late Qing constitutional movement of 1905–1911 and the vast borderland regions of the Qing Empire–that is, Mongolia, Tibet, and Xinjiang. It traces how intellectuals and officials concerned with devising constitutional policies foresaw the integration of these regions into the nascent parliamentary institutions at the provincial and central levels. The article argues that the status of the borderlands played a significant role in late Qing constitutional debates, and that debates on borderland constitutionalism were a phenomenon of a wider constitutional wave affecting Eurasia in the 1900s. Chinese intellectuals and officials felt the competition of the emerging parliamentary institutions in Russia and the Ottoman Empire, and anticipating that constitutional and parliamentarist movements among Mongols, Tibetans, and Turki could lead to the separation of the respective regions, they hoped that parliamentary representation, albeit limited, would be an instrument against centrifugal tendencies on the borders. Hence, they called for constitutional reforms in China and for the inclusion of the borderland populations into the new parliamentary institutions. Yet, arguing with the sparse population of the borderlands as well as with their alleged economic and cultural backwardness, they denied the direct application of the constitutional plan to these territories. The differentiated policies eventually applied to the borderlands were a lackluster compromise between these conflicting interests.
The Role of Bisphosphonates Prior to Denosumab Treatment on Rebound Fractures: A Mini Review
Arthur Costa Inojosa,Laís Mendes,Leonardo Bandeira,Francisco Bandeira 대한골대사학회 2022 대한골대사학회지 Vol.29 No.4
Denosumab is a potent anti-resorptive medication used to treat patients at high risk for osteoporosis; however, its beneficial effects on the skeletal system are quickly reversed after discontinuation. In contrast, bisphosphonates (BPs) are anti-resorptive agents with residual effects on the bone matrix; thus, these are capable of preserving bone mass for a long time. Therefore, subsequent anti-resorptive treatment with BPs is mandatory to prevent rebound fractures. Furthermore, BP administration before denosumab treatment appears to be a reasonable strategy for reducing hyperactivation of bone remodeling. In this review, we summarize the effects of BP administration before denosumab treatment in preventing rebound fractures after denosumab discontinuation.
Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0
Deutsch, Eric W.,Lane, Lydie,Overall, Christopher M.,Bandeira, Nuno,Baker, Mark S.,Pineau, Charles,Moritz, Robert L.,Corrales, Fernando,Orchard, Sandra,Van Eyk, Jennifer E.,Paik, Young-Ki,Weintraub, S American Chemical Society 2019 JOURNAL OF PROTEOME RESEARCH Vol.18 No.12
<P>The Human Proteome Organization’s (HUPO) Human Proteome Project (HPP) developed Mass Spectrometry (MS) Data Interpretation Guidelines that have been applied since 2016. These guidelines have helped ensure that the emerging draft of the complete human proteome is highly accurate and with low numbers of false-positive protein identifications. Here, we describe an update to these guidelines based on consensus-reaching discussions with the wider HPP community over the past year. The revised 3.0 guidelines address several major and minor identified gaps. We have added guidelines for emerging data independent acquisition (DIA) MS workflows and for use of the new Universal Spectrum Identifier (USI) system being developed by the HUPO Proteomics Standards Initiative (PSI). In addition, we discuss updates to the standard HPP pipeline for collecting MS evidence for all proteins in the HPP, including refinements to minimum evidence. We present a new plan for incorporating MassIVE-KB into the HPP pipeline for the next (HPP 2020) cycle in order to obtain more comprehensive coverage of public MS data sets. The main checklist has been reorganized under headings and subitems, and related guidelines have been grouped. In sum, Version 2.1 of the HPP MS Data Interpretation Guidelines has served well, and this timely update to version 3.0 will aid the HPP as it approaches its goal of collecting and curating MS evidence of translation and expression for all predicted ∼20 000 human proteins encoded by the human genome.</P> [FIG OMISSION]</BR>
Francisco José Arruda Mont`Alverne,Fabricio Oliveira Lima,Felipe de Araújo Rocha,Diego de Almeida Bandeira,Adson Freitas de Lucena,Henrique Coelho Silva,이진수,Raul Gomes Nogueira 대한뇌졸중학회 2020 Journal of stroke Vol.22 No.2
The benefit of mechanical thrombectomy (MT) in acute ischemic stroke (AIS) due to large vessel intracranial occlusions is directly related to the technical success of the procedures in achieving fast and complete reperfusion. While a precise definition of refractoriness is lacking in the literature, it may be considered when there is reperfusion failure, long procedural times, or high number of passes with the MT devices. Detailed knowledge about the causes for refractory MT in AIS is limited; however, it is most likely a multifaceted problem including factors related to the vascular anatomy and the underlying nature of the occlusive lesion amongst other factors. We aim to review the impact of several key unfavorable anatomical factors that may be encountered during endovascular AIS treatment and discuss potential bail-out strategies to these challenging situations.
Natasha Cordeiro dos Santos,Marc Miravitlles,Aquiles Assunção Camelier,Victor Durier Cavalcanti de Almeida,Roberto Rodrigues Bandeira Tosta Maciel,Fernanda Warken Rosa Camelier 대한결핵및호흡기학회 2022 Tuberculosis and Respiratory Diseases Vol.85 No.3
This study aimed to describe the prevalence of comorbidities associated with chronic obstructive pulmonary disease (COPD) and their relation with relevant outcomes. A systematic review based on the PRISMA methodology was performed from January 2020 until July 2021. The MEDLINE, Lilacs, and Scielo databases were searched to identify studies related to COPD and its comorbidities. Observational studies on the prevalence of comorbidities in COPD patients and costs with health estimates, reduced quality of life, and mortality were included. Studies that were restricted to one or more COPD pain assessments and only specific comorbidities such as osteoporosis, bronchitis, and asthma were excluded. The initial search identified 1,409 studies and after applying the inclusion and exclusion criteria, 20 studies were finally selected for analysis (comprising data from 447,459 COPD subjects). The most frequent COPD comorbidities were: hypertension (range, 17%–64.7%), coronary artery disease (19.9%–47.8%), diabetes (10.2%–45%), osteoarthritis (18%–43.8%), psychiatric conditions (12.1%–33%), and asthma (14.7%–32.5%). Several comorbidities had an impact on the frequency and severity of COPD exacerbations, quality of life, and mortality risk, in particular malignancies, coronary artery disease, chronic heart failure, and cardiac arrhythmias. Comorbidities, especially cardiovascular diseases and diabetes, are frequent in COPD patients, and some of them are associated with higher mortality.
Matheus Soldatelli,Álvaro de Oliveira Franco,Felipe Picon,Juliana Ávila Duarte,Ricardo Scherer,Janete Bandeira,Maxciel Zortea,Iraci Lucena da Silva Torres,Felipe Fregni,Wolnei Caumo 대한통증학회 2023 The Korean Journal of Pain Vol.36 No.1
Background: Resting-state functional connectivity (rs-FC) may aid in understanding the link between painmodulating brain regions and the descending pain modulatory system (DPMS) in fibromyalgia (FM). This study investigated whether the differences in rs-FC of the primary somatosensory cortex in responders and non-responders to the conditioned pain modulation test (CPM-test) are related to pain, sleep quality, central sensitization, and the impact of FM on quality of life. Methods: This cross-sectional study included 33 females with FM. rs-FC was assessed by functional magnetic resonance imaging. Change in the numerical pain scale during the CPM-test assessed the DPMS function. Subjects were classified either as non-responders (i.e., DPMS dysfunction, n = 13) or responders (n = 20) to CPM-test. A generalized linear model (GLM) and a receiver operating characteristic (ROC) curve analysis were performed to check the accuracy of the rs-FC to differentiate each group. Results: Non-responders showed a decreased rs-FC between the left somatosensory cortex (S1) and the periaqueductal gray (PAG) (P < 0.001). The GLM analysis revealed that the S1-PAG rs-FC in the left-brain hemisphere was positively correlated with a central sensitization symptom and negatively correlated with sleep quality and pain scores. ROC curve analysis showed that left S1-PAG rs-FC offers a sensitivity and specificity of 85% or higher (area under the curve, 0.78, 95% confidence interval, 0.63–0.94) to discriminate who does/does not respond to the CPM-test. Conclusions: These results support using the rs-FC patterns in the left S1-PAG as a marker for predicting CPM-test response, which may aid in treatment individualization in FM patients.