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Thu Hien Nguyen,Thi Thanh Ngan Nguyen,Bac Viet Le,Ngoc Minh Thanh,Thi Kim Lien Nguyen,Van Hai Nong,Huy Hoang Nguyen 한국유전학회 2017 Genes & Genomics Vol.39 No.3
Autism spectrum disorders (ASDs) are a group of neurodevelopmental disorders characterized by ritualistic- repetitive behaviors and impaired verbal and non-verbal communication. Boys are more likely to be diagnosed with ASD than girls. Genetics have been shown to play a key role in the etiology of autism. Many genes were found to be implicated in the inheritance of idiopathic autism. Analysis of mutation abnormalities associated with autism contributes significantly to the identification of autism candidate genes. Whole-exome sequencing has been shown as an application of the next generation sequencing technology used to determine the variations of all coding regions, or exons of the known genes. In the present study, we have found two novel heterozygous missense mutations (p.L111P and p.R3048C) on the RYR3 gene, which was located in the autism susceptibility region (15q14-q15) in a 9-year-old boy with ASD. Therefore, the sequence missense mutations provide the first suggestive link between a genetic abnormality in the RYR3 gene and a neurodevelopmental disorder.
Nguyen Thi Thanh Thao,Bui Hoang Bac 한양대학교 청정에너지연구소 2023 Journal of Ceramic Processing Research Vol.24 No.3
This study aimed to investigate the characteristics of three types of natural materials (KLC, KPT, and SSB) obtained fromregular deposits in Vietnam and their mullitization at calcinated temperatures of 1000 °C, 1200 °C, and 1400 °C. The sampleswere characterized by X-ray diffraction (XRD), X-ray fluorescence analysis (XRF), thermal analysis (the thermogravimetry/differential scanning calorimetry (TG/DSC)), and scanning electron microscope with energy-dispersive X-ray spectroscopy(SEM-EDS). The results indicated that kaolinite, halloysite, and sericite are the dominant minerals in the KLC, KPT, and SSBsamples, with particle sizes under 2 μm. These minerals' morphology was typical, with pseudo-hexagonal and stratifiedkaolinite, tubular halloysite, and thin platy sericite. The samples' chemical compositions are mainly SiO2 and Al2O3, followedby (K2O+Na2O), TiO2, and total iron content. Thermal analysis shows that the metakaolin phase is formed at differenttemperatures for the halloysite and kaolinite samples, as indicated by endothermic peaks at 411 °C for KPT and 436 °C forKLC. The quartz phase transition is also detected at different temperatures for the samples, with low-to-high temperatureendothermic peaks at 559 °C (KPT), 569 °C (KLC), and 575 °C (SSB). The mullitization process is observed to start attemperatures above 1000 °C and is critical at around 1400 °C, with well-crystal mullites appearing. The mineral compositionand morphology of the starting materials influence the size of the mullite crystals. SSB has larger mullite crystals than KLCand KPT at a sintering temperature of 1400 °C. It suggests that mineral composition, mineral morphology, and particle sizeof starting materials can also be essential factors influencing to mullitization process and ceramic products.
Huong, Truong Thu,Bac, Ta Phuong,Thang, Bui Doan,Long, Dao Minh,Quang, Le Anh,Dan, Nguyen Minh,Hoang, Nguyen Viet International Journal of Computer ScienceNetwork S 2021 International journal of computer science and netw Vol.21 No.6
Since machine learning was invented, there have been many different machine learning-based algorithms, from shallow learning to deep learning models, that provide solutions to the classification tasks. But then it poses a problem in choosing a suitable classification algorithm that can improve the classification/detection efficiency for a certain network context. With that comes whether an algorithm provides good performance, why it works in some problems and not in others. In this paper, we present a data-centric analysis to provide a way for selecting a suitable classification algorithm. This data-centric approach is a new viewpoint in exploring relationships between classification performance and facts and figures of data sets.
( Minh Hai Pham ),( Quan Anh Tuan Le ),( Hoang Bac Nguyen ),( Quang Hung Vu ),( Thai Ngoc Huy Tran ),( Hang Dang Khoa N Guyen ),( Thi Ngoc Sang Duong ),( Van Toan Tran ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Laparoscopic pancreaticoduodenectomy (LPD) is considered as a safe and effective procedure in well - selected patients and appropriate surgical technique. Our aim is to evaluate suitability of using protocol for LPD in treatment of periampullary cancer at a single team. Methods: case series Results: Indication for LPD included 37 cases with resectable tumors which were classified basing on NCCN. All witness evaluation risk of complications with PREPARE score, ASA and evaluation risk of postoperative pancreatic fistula (POPF) with FRS classification. There were 2 open conversions because of vein resections, accounting for 5.4%. Standard lymphadenectomy was performed in all of 37 cases. In term of PREPARE score, major complications (Clavien - Dindo >= III) were 17.8%, 0% and 0% (5/28, 0/5 and 0/2 cases) in low risk, intermediate risk and high risk group, respectively. All of cases had ASA I or II. POPF happened 11.1% (1/9), 4.1% (1/24) and 50% (1/2) in low risk, intermediate risk and high risk group, respectively. Frozen section was needed for R0 margin. Retrieved lymph nodes was 8 - 18 with 12 lymph nodes in average. Conclusions: Indication for LPD with resectable tumors is acceptable. ASA I or II is a safe measure to select patient for LPD. FRS classification shows appropriation to evaluate risk of POPF.
The first years of liver transplantation: experiences at a single center
Phu Hong Pham,Nghia Phuoc Phan,Viet Doan Khac Tran,Viet Quoc Dang,Thuan Duc Nguyen,Long Cong Duy Tran,Bac Hoang Nguyen 대한이식학회 2022 Korean Journal of Transplantation Vol.36 No.2
Background: The aim of this study was to analyze the first stages of progress in liver transplantation (LT) at a single center in Vietnam. Methods: This study analyzed data from patients and donors who participated in the LT program between August 2018 and December 2021 at University Medical Center, Ho Chi Minh City. Study measures included any difficulties encountered, as well as the post- LT outcomes for living donor LT (LDLT) and deceased donor LT (DDLT). The chi-square test and Kaplan Meier survival analysis were used to test the factors that influenced the outcomes. Results: A total of 18 adult recipients with LT (LDLT, n=16; DDLT, n=2) were included (mean age, 55.2±2.6 years; male, 88.9%). The most common post-LT complications were middle hepatic venous stenosis (20%) and graft rejection (22.2%). These compli- cations were observed in LDLT patients. For DDLT, graft rejection (50%) was the only complication recorded. The survival rates for recipients at 3 months, 6 months, and 1 year were 100%, 88.9%, and 88.9%, respectively. The LDs had their right livers without the middle hepatic veins harvested, and biliary leakage (6.25%) was the only complica- tion observed. There were no deaths among recipients or LDs during the operations or hospital stays. Conclusions: This study provides key details about the process of LT, and these positive outcomes support LT as an important therapy for end-stage liver disease and early he- patocellular carcinomas.