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Security Framework for Hybrid Wireless Mesh Protocol in Wireless Mesh Networks
( Mallikarjun Avula ),( Sang-gon Lee ),( Seong-moo Yoo ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.6
Wireless Mesh Networks (WMNs) are emerging as promising, convenient next generation wireless network technology. There is a great need for a secure framework for routing in WMNs and several research studies have proposed secure versions of the default routing protocol of WMNs. In this paper, we propose a security framework for Hybrid Wireless Mesh Protocol (HWMP) in WMNs. Contrary to existing schemes, our proposed framework ensures both end-to-end and point-to-point authentication and integrity to both mutable and non-mutable fields of routing frames by adding message extension fields to the HWMP path selection frame elements. Security analysis and simulation results show that the proposed approach performs significantly well in spite of the cryptographic computations involved in routing.
Functional Genomics of Adhesion, Invasion, and Mycelial Formation in Schizosaccharomyces pombe
Dodgson, James,Avula, Hema,Hoe, Kwang-Lae,Kim, Dong-Uk,Park, Han-Oh,Hayles, Jacqueline,Armstrong, John American Society for Microbiology 2009 EUKARYOTIC CELL Vol.8 No.8
<B>ABSTRACT</B><P>Investigation into the switch between single-celled and filamentous forms of fungi may provide insights into cell polarity, differentiation, and fungal pathogenicity. At the molecular level, much of this investigation has fallen on two closely related budding yeasts, <I>Candida albicans</I> and <I>Saccharomyces cerevisiae</I>. Recently, the much more distant fission yeast <I>Schizosaccharomyces pombe</I> was shown to form invasive filaments after nitrogen limitation (E. Amoah-Buahin, N. Bone, and J. Armstrong, Eukaryot. Cell 4:1287-1297, 2005) and this genetically tractable organism provides an alternative system for the study of dimorphic growth. Here we describe a second mode of mycelial formation of <I>S. pombe</I>, on rich media. Screening of an <I>S. pombe</I> haploid deletion library identified 12 genes required for mycelial development which encode potential transcription factors, orthologues of <I>S. cerevisiae</I> Sec14p and Tlg2p, and the formin For3, among others. These were further grouped into two phenotypic classes representing different stages of the process. We show that galactose-dependent cell adhesion and actin assembly are both required for mycelial formation and mutants lacking a range of genes controlling cell polarity all produce mycelia but with radically altered morphology.</P>
Harish Chander Dutt,Surjeet Singh,Bharathi Avula,Ikhlas A. Khan,Yashbir S. Bedi 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.2
Caralluma fimbriata extract has received Generally Recognized As Safe (GRAS) status for use as a nutraceutical to combat the most serious public health concern (i.e., obesity). More than 260 species grouped under the genus Caralluma (Family Apocynaceae) are distributed in tropical Asia and Mediterranean regions of the globe. Ethnobotanically,some species have been used as traditional and modern dietary ingredients to suppress appetite. Many species of Caralluma are commonly used as traditional medicine for the treatment of rheumatism, diabetes, leprosy, paralysis, and inflammation and have antimalarial, antitrypanosomal, anti-ulcer, antioxidant, antinociceptive, and antiproliferative activities. The genus is known for compounds like pregnane glycosides, flavonoid glycoside, flavones, magastigmane glycosides, pregnane steroids,steroidal glycosides, saturated and unsaturated hydrocarbons, aromatic and nonaromatic volatile compounds, and b-sitosterol. An extract of C. fimbriata (Slimaluna, Gencor Nutrients, Anaheim, CA, USA) is used as an anti-obesity agent and appetite suppressor. It is also seen that the pregnane glycosides isolated and identified from African Hoodia are reported as anti-obesity and appetite-suppressant compounds. On reviewing the studies undertaken on the chemistry, pharmacology, and therapeutic potential of Caralluma, it is concluded that the genus is also composed of pregnane glycosides as one of the major constituents. Availability of pregnane glycosides in Caralluma is an indication of the appetite-suppressant property of this genus. This coupled with the GRAS status of the extract of C. fimbriata has opened the possibility of developing an anti-obesity/appetite-suppressant product from other species of Caralluma. The main objective of this article is to review the studies undertaken on the plant in light of further research for anti-obesity drugs and nutraceuticals from species of Caralluma.
Kisspeptin regulates the development of caprine primordial follicles in vitro
Magamage, Manjula Priyantha Sumith,Sathagopam, Sriravali,Avula, Kiran,Madushanka, Di Neththi Nimesh,Velmurugan, Sathya The Korean Society of Animal Reproduction and Biot 2021 한국동물생명공학회지 Vol.36 No.1
Kisspeptin, a neuropeptide and the master controller of reproductive axis upstream to GnRH neurons, and its receptor are also expressed in extra-hypothalamic tissues, such as ovaries. As systemic kisspeptin has been shown to modulate follicular dynamics in cattle, we hypothesized that kisspeptin has direct actions on the ovarian follicular development. We also hypothesized that kisspeptin regulation of primordial follicle development is via modulation of VEGF expression. In order to test these hypotheses, we cultured caprine ovarian cortical strips in vitro for 7 days with supplementation of kisspeptin at 1, 10 and 100 µM concentration and observed the development of primordial follicles into intermediate, primary and secondary follicles. We also studied the alteration in the expression profile of VEGF and VEGF transcript variant 2 mRNA during follicular development in the presence of kisspeptin. We confirmed the presence of GPR54 in goat ovaries in our preliminary studies. Supplementation of kisspeptin at 1 and 10 µM concentration facilitated the development of primordial follicles into intermediate, primary and secondary follicles with less number of degenerated follicles while the same at 100 µM resulted in degeneration of follicles. We observed a drastic increase in the expression profile of VEGF and VEGF transcript variant 2 mRNA upon culture which was independent of kisspeptin treatment. In conclusion, our studies show that kisspeptin facilitates ovarian primordial development in vitro.
Design of Wideband Elliptical Ring Monopole Antenna Using Characteristic Mode Analysis
Bhaskara Rao Perli,Maheswara Rao Avula 한국전자파학회JEES 2021 Journal of Electromagnetic Engineering and Science Vol.21 No.4
This paper presents the systematic design of an elliptical ring monopole wideband antenna using characteristic mode analysis. The modal analysis is used to analyze the bandwidth and the radiation performance of the radiating patch. The resonance frequencies of three characteristic modes are close to each other with similar modal current distributions and characteristic fields. These three characteristic modes are simultaneously excited by an effective feeding technique. The proposed model achieves wideband characteristics. The proposed model is printed on an inexpensive FR4 substrate with a size of 20 mm × 18 mm × 1.6 mm and has a wide impedance bandwidth of 124.4% in the range of 3.6–15.46 GHz. The prototype has been fabricated and the measured results show good agreement with simulated results. The antenna will cover WLAN, WiMAX, Wi-Fi, and X-band applications.
Kisspeptin regulates the development of caprine primordial follicles in vitro
Manjula Priyantha Sumith Magamage,Sriravali Sathagopam,Kiran Avula,Di Neththi Nimesh Madushanka,Sathya Velmurugan 한국동물생명공학회(구 한국동물번식학회) 2021 Journal of Animal Reproduction and Biotechnology Vol.36 No.1
Kisspeptin, a neuropeptide and the master controller of reproductive axis upstream to GnRH neurons, and its receptor are also expressed in extrahypothalamic tissues, such as ovaries. As systemic kisspeptin has been shown to modulate follicular dynamics in cattle, we hypothesized that kisspeptin has direct actions on the ovarian follicular development. We also hypothesized that kisspeptin regulation of primordial follicle development is via modulation of VEGF expression. In order to test these hypotheses, we cultured caprine ovarian cortical strips in vitro for 7 days with supplementation of kisspeptin at 1, 10 and 100 μM concentration and observed the development of primordial follicles into intermediate, primary and secondary follicles. We also studied the alteration in the expression profile of VEGF and VEGF transcript variant 2 mRNA during follicular development in the presence of kisspeptin. We confirmed the presence of GPR54 in goat ovaries in our preliminary studies. Supplementation of kisspeptin at 1 and 10 μM concentration facilitated the development of primordial follicles into intermediate, primary and secondary follicles with less number of degenerated follicles while the same at 100 μM resulted in degeneration of follicles. We observed a drastic increase in the expression profile of VEGF and VEGF transcript variant 2 mRNA upon culture which was independent of kisspeptin treatment. In conclusion, our studies show that kisspeptin facilitates ovarian primordial development in vitro.