Shipwrecks and graves: Their treatment as intangible heritage

Elena Perez-Alvaro 국립민속박물관 2022 International Journal of Intangible Heritage Vol.17 No.-

The treatment and management of human remains in land archaeology has been a debated topic. However, in the field of underwater cultural heritage, the references are almost non-existent. The importance of the topic has already been recognised, since some nations have established legal frameworks to protect those human remains. In addition, the term is included in the definition of ‘underwater cultural heritage’ under the 2001 UNESCO Convention on the Protection of the Underwater Cultural Heritage (UNESCO 2001). However, the ethical dilemmas around the topic have not been discussed, and protocols for the management of shipwrecks with or without human remains have not been established. This article discusses the management of human remains as part of an underwater cultural heritage site and the ethical issues that this complicated heritage presents at an international level. In this regard, it looks both at those shipwrecks that still preserve human remains and those where the remains have disappeared but were once there. It also introduces three concepts, applied for the first time to human remains, based on a variety of cultural attitudes: absent, invisible and intangible heritage.

Gesture-based Teleoperation using a Holonomic Robot

Alvaro Uribe,Byron Perez-Gutierrez,Silas Alves 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

This work presents the development and integration of an user interface (UI) framework based on various current input devices that take advantage of our ergonomics. The purpose is to teleoperate a holonomic robot using upper member gestures and postures for studying the suitable of such interfaces when programming and interacting with a mobile robot. As performance vary from UI to UI the framework is focused to be used as a complementary industrial or didactic tool thus, changing how inexperience users tackle their first impressions when working with mobile robots while performing simple gesture-based teleoperation tasks.

Arm-like Mechanism User Interface for 3D Animation

Alvaro Uribe-Quevedo,Hernando Leon,Byron Perez-Gutierrez 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10

Character animation is traditionally accomplished using traditional input devices such as keyboards, mouse, joysticks, programming pads or motion capture systems with elevated costs making them unavailable to common users. However, 3D User Interfaces such as electromechanical sensors, depth maps and vision tracking have been changing how we interact with information in several applications and common use devices. Animation using 3D user interfaces allows more natural, fluent and precise queues of motion, which is why this work presents the implementation of an anthropomorphic mechanism for motion capture through flexion/extension and abduction/adduction with an arm mechanism of four Degrees of Freedom. The goal is to present the feasibility of assembling a low cost device that allows tracking suitable motion for performing an animation on a virtual character.

Perturbation of Maize Phenylpropanoid Metabolism by an AvrE Family Type III Effector from <i>Pantoea stewartii</i>

Asselin, Jo Ann E.,Lin, Jinshan,Perez-Quintero, Alvaro L.,Gentzel, Irene,Majerczak, Doris,Opiyo, Stephen O.,Zhao, Wanying,Paek, Seung-Mann,Kim, Min Gab,Coplin, David L.,Blakeslee, Joshua J.,Mackey, Da American Society of Plant Biologists 2015 Plant Physiology Vol.167 No.3

<P><I>The virulence activity of an effector protein belonging to the widely conserved AvrE family is linked to its ability to cause system-wide reprogramming of phenylpropanoid metabolism in susceptible maize seedlings.</I></P><P>AvrE family type III effector proteins share the ability to suppress host defenses, induce disease-associated cell death, and promote bacterial growth. However, despite widespread contributions to numerous bacterial diseases in agriculturally important plants, the mode of action of these effectors remains largely unknown. WtsE is an AvrE family member required for the ability of <I>Pantoea stewartii</I> ssp. <I>stewartii</I> (<I>Pnss</I>) to proliferate efficiently and cause wilt and leaf blight symptoms in maize (<I>Zea mays</I>) plants. Notably, when WtsE is delivered by a heterologous system into the leaf cells of susceptible maize seedlings, it alone produces water-soaked disease symptoms reminiscent of those produced by <I>Pnss</I>. Thus, WtsE is a pathogenicity and virulence factor in maize, and an <I>Escherichia coli</I> heterologous delivery system can be used to study the activity of WtsE in isolation from other factors produced by <I>Pnss</I>. Transcriptional profiling of maize revealed the effects of WtsE, including induction of genes involved in secondary metabolism and suppression of genes involved in photosynthesis. Targeted metabolite quantification revealed that WtsE perturbs maize metabolism, including the induction of coumaroyl tyramine. The ability of mutant WtsE derivatives to elicit transcriptional and metabolic changes in susceptible maize seedlings correlated with their ability to promote disease. Furthermore, chemical inhibitors that block metabolic flux into the phenylpropanoid pathways targeted by WtsE also disrupted the pathogenicity and virulence activity of WtsE. While numerous metabolites produced downstream of the shikimate pathway are known to promote plant defense, our results indicate that misregulated induction of phenylpropanoid metabolism also can be used to promote pathogen virulence.</P>

Association between Family Functionality and Depression: A Systematic Review and Meta-Analysis

Daniel Guerrero-Muñoz,Diana Salazar,Victoria Constain,Alvaro Perez,Carlos Andrés Pineda-Cañar,Herney Andrés García-Perdomo 대한가정의학회 2021 Korean Journal of Family Medicine Vol.42 No.2

Background: Different scales have attempted to assess various aspects of family dynamics and structures. Good family function seems to allow for better prognoses for basic diseases and appears to be a predictor of depression. The aim of this study was to determine the association between family functionality and depression. Methods: This is a systematic review and meta-analysis including cross-sectional, cohort, and case-control studies using validated instruments such as the Family APGAR (Adaptability, Partnership, Growth, Affection, and Resolve) and Family Adaptability and Cohesion Evaluation Scale III. A search strategy was designed for the MEDLINE, Embase, Central, and LILACS databases along with data saturation through a search of unpublished literature from the onset of the databases to the present. The categorical variables are expressed in terms of odds ratios (OR), and the statistical analysis was carried out using Review Manager ver. 5.31 (The Cochrane Collaboration, Oxford, UK) using forest plots with corresponding 95% confidence intervals (CI). A fixed-effect model was used according to the expected heterogeneity, expressed in terms of I2. The risk of bias was evaluated using the MINORS (methodological index for non-randomized studies) tool. Results: A total of 1,519 studies were found, of which 10 were selected for the qualitative synthesis and four were chosen for the meta-analysis. The result for the association between family dysfunction and depression yielded an OR (95% CI) of 3.72 (2.70 to 5.12) and I2 of 24%. Conclusion: Family dysfunction and depression are strongly associated.

Cell membrane enolase of Aedes albopictus C6/36 cells is involved in the entrance mechanism of dengue virus (DENV)

Brito-Carreón Cesar Armando,Zavala-Maldonado Karla,Suárez-Andino Erika Ivette,David Randy E.,Perez- Ramírez Gerardo,Diaz-Badillo Alvaro,Muñoz María de Lourdes 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.2

Currently, there are no antiviral drugs that effectively reduce the risks and treat the symptoms associated with dengue virus (DENV). Consequently, efforts remain primarily focused on transmission reduction. One such effort concerns DENV receptors in mosquito vectors Aedes aegypti and Aedes albopictus. Despite a lack of direct evidence demonstrating the binding of DENV to cells in mosquito vectors, one putative DENV binding protein has been α-enolase. To develop a deeper understanding, this study tested whether DENV proteins bind to enolase localized in the cytoplasmic membrane of C6/36 cells using both anti-enolase-specific antibodies, and by colocalization analysis, using confocal microscopy. Additionally, to probe the interaction of enolase with the DENV E protein, we performed a docking analysis using PatchDock and FireDock software packages. Study results demonstrate that the DENV E protein interacts with enolase in the plasma membrane of C6/36 cells of Ae. albopictus. Specific anti-enolase antibodies were found to inhibit DENV infection of these cells. Moreover, enolase was found to be localized to the cytoplasmic mem brane, cytoplasm, and nucleus. These combined findings suggest that enolase participates in the entrance mechanism of DENV into vector cells.