Plasma zinc's alter ego is a low-molecular-weight humoral factor

Ou, Ou,Allen-Redpath, Keith,Urgast, Dagmar,Gordon, Margaret-Jane,Campbell, Gill,Feldmann, Jö,rg,Nixon, Graeme F.,Mayer, Claus-Dieter,Kwun, In-Sook,Beattie, John H. The Federation of American Societies for Experimen 2013 The FASEB Journal Vol.27 No.9

<P>Mild dietary zinc deprivation in humans and rodents has little effect on blood plasma zinc levels, and yet cellular consequences of zinc depletion can be detected in vascular and other tissues. We proposed that a zinc-regulated humoral factor might mediate the effects of zinc deprivation. Using a novel approach, primary rat vascular smooth muscle cells (VSMCs) were treated with plasma from zinc-deficient (<1 mg Zn/kg) or zinc-adequate (35 mg Zn/kg, pair-fed) adult male rats, and zinc levels were manipulated to distinguish direct and indirect effects of plasma zinc. Gene expression changes were analyzed by microarray and qPCR, and incubation of VSMCs with blood plasma from zinc-deficient rats strongly changed the expression of >2500 genes, compared to incubation of cells with zinc-adequate rat plasma. We demonstrated that this effect was caused by a low-molecular-weight (∼2-kDa) zinc-regulated humoral factor but that changes in gene expression were mostly reversed by adding zinc back to zinc-deficient plasma. Strongly regulated genes were overrepresented in pathways associated with immune function and development. We conclude that zinc deficiency induces the production of a low-molecular-weight humoral factor whose influence on VSMC gene expression is blocked by plasma zinc. This factor is therefore under dual control by zinc.—Ou, O., Allen-Redpath, K., Urgast, D., Gordon, M.-J., Campbell, G., Feldmann, J., Nixon, G. F., Mayer, C.-D., Kwun, I.-S., and Beattie, J. H. Plasma zinc's alter ego is a low-molecular-weight humoral factor.</P>

CBD 프로세스가 갖춰야 할 기본 요소들

Paul Allen(Paul Allen),김경주(Kyungju Kim) 한국정보과학회 2001 정보과학회지 Vol.19 No.2

곽안련 선교사 60년 회고록

Charles Allen Clark,Charles Allen Clark 신학지남사 1993 신학지남 Vol.60 No.4

"Know Thyself": Proficient Humanity, the End-Continuous Assessment, the Means

William B. Allen,Carol Allen 서울행정학회 2003 서울행정학회 학술대회 발표논문집 Vol.- No.-

보건관리자의 직능별 직업 및 조직 헌신도에 대한 비교 연구

이경용,이기범,Natalie j.Allen,조영숙 한국직업건강간호학회 1998 한국직업건강간호학회지 Vol.7 No.1

This study was carried out in order to confirm the reliability and validity of the commitment inventor developed by Meyer and Allen, and to investigate commitment level of health manager, to compare two different professionals of health manager such industrial health nurse and industrial hygienist to find out some characteristics that have effect on commitment. This survey was done by self -administered questionnaire to 227 respondents as the trainees of Industrial Safety Training Center, KISCO from June to December 1996. Authors classified commitment into two categories : professional commitment and organizational commitment, and these two types of commitments have three different aspects affective, continuance, and normative commitment based on Meyer's inventory. The results were as follows: 1. Items of whole scales of the both type of commitments have three factors that represent three aspects of commitment ; affective, continuance, and normative commitment. This means that each type of commitment was reliable to use as measurement tool of three different aspects of commitment. Classification of items by factor analysis was more consistent in professional commitment than organizational commitment, Among 16 items of organizational commitment, four items were classified into different aspects of commitment with similar factor loading. 2. Commitment level of industrial health nurse was higher than that of industrial hygienist in affective, continuance professional commitment controlled by other characteristics. These differences can be due to other characteristics of specific task and background of health managers that were not used in this study. 3. The level of affective professional commitment was statistically different in age, sex, education level, and that of organizational commitment was statistically different in only two variables such as age, and job tenure. The level of continuance professional and organizational commitments were different in sex group, but past history of employ went have effect on continuance organizational commitment. The level of normative organizational commitment was affected by only age. As the above results, the tools of measurement of commitment developed by Meyer and Allen can be useful to measure the level of commitment of health manager. Three aspects of two types of commitments were influenced by different characteristics of health manager. Authors suggested future study on the affecting variables to the commitment such as background, task of health manager and organizational characteristics.

U.S. and Global Recovery: For Real? - Prospects and Risks

Allen Sinai 세계경제연구원 2003 세계경제연구원 간행물 Vol.- No.-

Adrienne Rich

Allen D, wIlliams 啓明專門大學 産業開發硏究所 2001 啓明硏究論叢 Vol.19 No.1

In much of today's writing we are finding a return to the "I" as in me the writer or poet' in a manner that has not been seen so prominently since the Romantics. While this perspective has been shunned by most modern writers. it is finding new light. and a new life, in a surprisingly different form in modern feminist writings. Though it is a return to an "I" of a different sort it is a perspective that is worthy of some consideration, and at the very least provides an interesting point from which to view both modern writings and those of the past. The Feminist "I" is one still searching for itself and perhaps we can find no better evidence of this than in the writings of Adrienne Rich. As a critical theory. this search for a new perspective from which to approach literature that might lead to a better and more lasting understanding of the texts has itself undergone many changes. Led by the landmark works of Virginia Woolf and her essay "A Room of Her Own", the feminists, though I despair at using the term for all of its self-wrought negativity, perspective and view of the self. a self long suppressed and concealed so even it's possessor was not aware of it's presence or damaged and possibly untrue state, came into light as a force with which to be reckoned. While this cannot be seen as a completely new revelation in critical thinking, the somewhat radical view presented by today's feminists is one to give a reader pause for thought: the need to review texts not only for what they might show us of the nature of women's roles, as writers or mothers, but also that they may in fact be writing from a perspective not truly their own and most certainly not in a language they were controlling. This paper will not be arguing the validity of their claim, but will instead be an attempt to shed some light on the foundations from which this thought sprang and the direction it is or should be heading according to Rich's leading voice.

THE ECU AND THE TRANSITION TO EUROPEAN MONETARY UNION

ALLEN, POLLY REYNOLDS 한국국제경제학회 1992 International Economic Journal Vol.6 No.1

The private ECU markets have developed as Eurocurrency markets because of the ECU's portfolio attractions ㅡ a combination of return and exchange risk unobtainable at such low cost from the national currencies. The private ECU functions in the Eurocurrency and foreign exchange markets as a true currency, but supports very few transactions in good and services and depends upon the private banks to maintain its basket exchange rate. The possiblities of the ECU being used more for transactions, with liquidity implications for the EC, and of the banks failing to maintain the basket rate, suggest the need for an EC insitution to issue base money ECUs during the transition to monetary union.

Collapse of Magnetised, Singular Isothermal Toroids

ALLEN ANTHONY,SHU FRANK,LI ZHI- YUN The Korean Astronomical Society 2001 Journal of The Korean Astronomical Society Vol.34 No.4

This poster summarizes numerical collapse calculations of non-rotating and rotating singular, isothermal toroids that employed the zeus2d (Norman and Stone 1992) magnetohydrodynamics package. In the non-rotating collapse calculations, it is seen that infall proceeds at a constant rate and magnetically supported, high density pseudo-disks form in the equatorial plane. With rotating clouds, however, toroidal magnetic fields grow as infall proceeds, teaming with angular momentum to slow the inflow to the center and generate outflow.

Personal and Work Related Correlates of Professional Self-Efficacy of Teachers in the Bachelor in Industrial Technology Program of the Bulacan State University

Allen N. Maroma,Dolly P. Maroma ASCONS 2017 INTERNATIONAL JOURNAL OF EMERGING MULTIDISCIPLINAR Vol.1 No.1

The study aimed to the professional self-efficacy levels of Industrial Technology teachers and determine how personal and work-related factors correlate to this. Questionnaires were administered to the respondents who were purposively chosen for this research. Demographic data were taken as personal-related factors, while facilities and equipment, program culture an administrative support and professional organization were considered as indicators of work-related factors. To discern professional efficacy, knowledge improvement, attitudes and practices were taken into account as indicators. Findings showed that Work related variables are predominantly significantly related to professional efficacy rather than personal-related variables. Program culture has positive significant correlation with knowledge improvement as an indicator of professional efficacy. Administrative support and program culture have positive significant correlation with attitude as an indicator of professional efficacy.. Hence, it was concluded that work-related rather than personal-related factors had significantly influenced teachers' perception of professional self-efficacy.