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      • KCI등재후보

        Research on the probability model of basic wind speed estimation in China

        Cheng Xiang,Airong Chen,Qiheng Li,Rujin Ma 한국풍공학회 2021 Wind and Structures, An International Journal (WAS Vol.32 No.6

        Wind speed is one of the most critical parameters in predicting structural performance under wind effects. In most of the current standards and codes, the design reference wind speed is usually determined by fitting a typical probability distribution model based on the historical wind speed data. However, a single distribution model is generally insufficient to reflect the regional differences in wind characteristics. Therefore, in this research, the optimal probability is selected to determine the extreme wind speed in different regions in China based on the fourth-order linear moment method (FLMM). Firstly, several probability models for estimating extreme wind speed distribution are introduced. Then, the optimal model, as well as the relative parameters, are determined by the linear moments (L-moments) method, and the one with the minimum value of the fourth-order linear moment between the probability model and the sample is taken as the optimal distribution. Finally, the extreme wind speed of each meteorological station is estimated according to the obtained optimal distribution, and the results are compared with the recorded extreme wind speed of typical metrological stations as well as that in the previous version of specification (JTG/T D60-01-2004). Compared with the traditional method that adopting a single distribution model-based wind speed estimation, the extreme wind speed obtained by the proposed method possessed higher accuracy.

      • KCI등재

        A multiscale numerical simulation approach for chloride diffusion and rebar corrosion with compensation model

        Xi Tu,Zhengliang Li,Airong Chen,Zichao Pan 사단법인 한국계산역학회 2018 Computers and Concrete, An International Journal Vol.21 No.4

        Refined analysis depicting mass transportation and physicochemical reaction and reasonable computing load with acceptable DOFs are the two major challenges of numerical simulation for concrete durability. Mesoscopic numerical simulation for chloride diffusion considering binder, aggregate and interfacial transition zone is unable to be expended to the full structure due to huge number of DOFs. In this paper, a multiscale approach of combining both mesoscopic model including full-graded aggregate and equivalent macroscopic model was introduced. An equivalent conversion of chloride content at the Interfacial Transition Layer (ITL) connecting both models was considered. Feasibility and relative error were discussed by analytical deduction and numerical simulation. Case study clearly showed that larger analysis model in multiscale model expanded the diffusion space of chloride ion and decreased chloride content in front of rebar. Difference for single-scale simulation and multiscale approach was observed. Finally, this paper addressed some worth-noting conclusions about the chloride distribution and rebar corrosion regarding the configuration of rebar placement, rebar diameter, concrete cover and exposure period.

      • KCI등재

        Experimental Study on Shear Behavior of Precast Concrete Segmental Beams with Hybrid Tendons and Dry Joints

        Haibo Jiang,Yuhong Li,Airong Liu,Li Chen,Yuanhang Chen,Jie Xiao 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.10

        A series of tests were carried out on nine specimens to improve the understanding of the shear behavior of precast concrete segmental beams (PCSBs) with hybrid tendons and dry joints. The influences of the tendon layout (hybrid tendons and external tendons), shear span ratio, and joint type (monolithic joints, and dry joints) on shear behavior of PCSBs were experimentally studied. The test results indicated that hybrid tendons slightly improved the shear strength and stiffness of PCSBs with dry joints compared to external tendons. The shear strengths of PCSBs with hybrid tendons and dry joints reduced with an increasing shear span ratio. Compared to monolithic beams with hybrid tendons, the dry joints slightly decreased the shear strength and enhanced the nonlinear behavior of PCSBs with hybrid tendons. The shear strengths of PCSBs and monolithic beams can be conservatively predicted by the AASHTO, Chinese code, and British Standard. The strut-and-tie model of prestressing force can accurately estimate the shear strengths of all the beams.

      • KCI등재

        Knockdown of microtubule actin crosslinking factor 1 inhibits cell proliferation in MC3T3-E1 osteoblastic cells

        ( Lifang Hu ),( Peihong Su ),( Runzhi Li ),( Kun Yan ),( Zhihao Chen ),( Peng Shang ),( Airong Qian ) 생화학분자생물학회(구 한국생화학분자생물학회) 2015 BMB Reports Vol.48 No.10

        Microtubule actin crosslinking factor 1 (MACF1), a widely expressed cytoskeletal linker, plays important roles in various cells by regulating cytoskeleton dynamics. However, its role in osteoblastic cells is not well understood. Based on our previous findings that the association of MACF1 with F-actin and microtubules in osteoblast-like cells was altered under magnetic force conditions, here, by adopting a stable MACF1- knockdown MC3T3-E1 osteoblastic cell line, we found that MACF1 knockdown induced large cells with a binuclear/multinuclear structure. Further, immunofluorescence staining showed disorganization of F-actin and microtubules in MACF1-knockdown cells. Cell counting revealed significant decrease of cell proliferation and cell cycle analysis showed an S phase cell cycle arrest in MACF1-knockdown cells. Moreover and interestingly, MACF1 knockdown showed a potential effect on cellular MTT reduction activity and mitochondrial content, suggesting an impact on cellular metabolic activity. These results together indicate an important role of MACF1 in regulating osteoblastic cell morphology and function. [BMB Reports 2015; 48(10): 583-588]

      • KCI등재

        Simultaneous desulfurization and denitrogenation of model fuels by polyethylene glycol-modified resorcinol/formaldehyde resin-derived carbon spheres

        Jie Wen,Dongdong Zhao,Yingying Lu,Jing Huang,Yanping Li,Hui Zhang,Airong Li 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.7

        A series of resorcinol/formaldehyde (RF) resin-derived carbon spheres modified by polyethylene glycol (PEG) were prepared. The effects of PEG addition time during hydrothermal treatment and molecular weight on the pore structure, surface acidic groups, particle size, and adsorption performances of the obtained spherical activated carbons were investigated. Two types of model fuel containing indole, quinoline, and dibenzothiophene (DBT) as target adsorbates were prepared to evaluate the adsorption performances of the spheres, which increased in the order of DBT<quinoline<indole. Hydrogen bonding may be critical in the removal of indole. Both the surface area and oxygen- containing functional groups influenced the adsorption capacity, with the latter significantly influenced by PEG addition time. PEG addition during the RF resin cross-linking stage sharply reduced the total concentration of acidic groups on the carbon sphere surfaces. The adsorption thermodynamics and kinetics of nitrogen and sulfur compounds were also investigated. The adsorption isotherms of all S/N species were of the Freundlich type at 25 oC. The pseudo-second-order rate equation well described the adsorption kinetics. Both external diffusion and intra-particle diffusion controlled the rate of adsorption.

      • KCI등재

        Polymorphisms in Epigenetic and Meat Quality Related Genes in Fourteen Cattle Breeds and Association with Beef Quality and Carcass Traits

        Xuan Liu,Tahir Usman,Yachun Wang,Zezhao Wang,Xianzhou Xu,Meng Wu,Yi Zhang,Xu Zhang,Qiang Li,Lin Liu,Wanhai Shi,Chunhua Qin,Fanjun Geng,Congyong Wang,Rui Tan,Xixia Huang,Airong Liu,Hongjun Wu,Shixin Ta 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.4

        Improvement for carcass traits related to beef quality is the key concern in beef production. Recent reports found that epigenetics mediates the interaction of individuals with environment and nutrition. The present study was designed to analyze the genetic effect of single nucleotide polymorphisms (SNPs) in seven epigenetic-related genes (DNMT1, DNMT3a, DNMT3b, DNMT3L, Ago1, Ago2, and HDAC5) and two meat quality candidate genes (CAPN1 and PRKAG3) on fourteen carcass traits related to beef quality in a Snow Dragon beef population, and also to identify SNPs in a total of fourteen cattle populations. Sixteen SNPs were identified and genotyped in 383 individuals sampled from the 14 cattle breeds, which included 147 samples from the Snow Dragon beef population. Data analysis showed significant association of 8 SNPs within 4 genes related to carcass and/or meat quality traits in the beef populations. SNP1 (13154420A>G) in exon 17 of DNMT1 was significantly associated with rib-eye width and lean meat color score (p<0.05). A novel SNP (SNP4, 76198537A>G) of DNMT3a was significantly associated with six beef quality traits. Those individuals with the wild-type genotype AA of DNMT3a showed an increase in carcass weight, chilled carcass weight, flank thicknesses, chuck short rib thickness, chuck short rib score and in chuck flap weight in contrast to the GG genotype. Five out of six SNPs in DNMT3b gene were significantly associated with three beef quality traits. SNP15 (45219258C>T) in CAPN1 was significantly associated with chuck short rib thickness and lean meat color score (p<0.05). The significant effect of SNP15 on lean meat color score individually and in combination with each of other 14 SNPs qualify this SNP to be used as potential marker for improving the trait. In addition, the frequencies of most wild-type alleles were higher than those of the mutant alleles in the native and foreign cattle breeds. Seven SNPs were identified in the epigenetic-related genes. The SNP15 in CAPN1 could be used as a powerful genetic marker in selection programs for beef quality improvement in the Snow Dragon Beef population.

      • SCIESCOPUSKCI등재

        Polymorphisms in Epigenetic and Meat Quality Related Genes in Fourteen Cattle Breeds and Association with Beef Quality and Carcass Traits

        Liu, Xuan,Usman, Tahir,Wang, Yachun,Wang, Zezhao,Xu, Xianzhou,Wu, Meng,Zhang, Yi,Zhang, Xu,Li, Qiang,Liu, Lin,Shi, Wanhai,Qin, Chunhua,Geng, Fanjun,Wang, Congyong,Tan, Rui,Huang, Xixia,Liu, Airong,Wu, Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.4

        Improvement for carcass traits related to beef quality is the key concern in beef production. Recent reports found that epigenetics mediates the interaction of individuals with environment and nutrition. The present study was designed to analyze the genetic effect of single nucleotide polymorphisms (SNPs) in seven epigenetic-related genes (DNMT1, DNMT3a, DNMT3b, DNMT3L, Ago1, Ago2, and HDAC5) and two meat quality candidate genes (CAPN1 and PRKAG3) on fourteen carcass traits related to beef quality in a Snow Dragon beef population, and also to identify SNPs in a total of fourteen cattle populations. Sixteen SNPs were identified and genotyped in 383 individuals sampled from the 14 cattle breeds, which included 147 samples from the Snow Dragon beef population. Data analysis showed significant association of 8 SNPs within 4 genes related to carcass and/or meat quality traits in the beef populations. SNP1 (13154420A>G) in exon 17 of DNMT1 was significantly associated with rib-eye width and lean meat color score (p<0.05). A novel SNP (SNP4, 76198537A>G) of DNMT3a was significantly associated with six beef quality traits. Those individuals with the wild-type genotype AA of DNMT3a showed an increase in carcass weight, chilled carcass weight, flank thicknesses, chuck short rib thickness, chuck short rib score and in chuck flap weight in contrast to the GG genotype. Five out of six SNPs in DNMT3b gene were significantly associated with three beef quality traits. SNP15 (45219258C>T) in CAPN1 was significantly associated with chuck short rib thickness and lean meat color score (p<0.05). The significant effect of SNP15 on lean meat color score individually and in combination with each of other 14 SNPs qualify this SNP to be used as potential marker for improving the trait. In addition, the frequencies of most wild-type alleles were higher than those of the mutant alleles in the native and foreign cattle breeds. Seven SNPs were identified in the epigenetic-related genes. The SNP15 in CAPN1 could be used as a powerful genetic marker in selection programs for beef quality improvement in the Snow Dragon Beef population.

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