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문병현,송주열,이현성,손경규,엄태환,김정우,김아름 대구대학교 정보통신연구소 2004 情報通信硏究 Vol.3 No.2
The system designed in this paper, can mark the interior state of greenhouse using sensors of temperature, humidity and illumination on greenhouse interior by greenhouse system for farm village area's agriculture automation. And, the real time monitor is possible real time monitoring by camera. Also, system that can supply water using spring cooler system and humidifier. The proposed system can sustain a designed environment of the greenhouse through rentilation fan, fluorescent light and roof door control. TCP/IP is used for the remote control of state the sensors in the client program. 본 논문에서 설계된 시스템은 농촌 지역의 농업 자동화를 위한 온실 시스템으로 온실 내부에 온도, 습도, 조도 센서를 이용한 온실 내부의 상태를 표시할 수 있으며 카메라를 이용하여 실시간 관측이 가능하다. 또한 본 시스템은 지붕 개폐, 스프링 쿨러와 가습기를 이용한 수분 공급, 환풍기, 형광등 등을 통하여 온실 내부의 환경을 유지시킬 수 있다. 모든 센서를 이용한 상태와 온실 제어를 TCP/IP를 이용한 클라이언트 프로그램에서 원격으로 관리할 수 있다.
Lee, Ah-Reum,Lee, Sook-Jeong,Lee, Minho,Nam, Miyoung,Lee, Sol,Choi, Jian,Lee, Hye-Jin,Kim, Dong-Uk,Hoe, Kwang-Lae ACADEMIC PRESS 2018 TOXICOLOGICAL SCIENCES Vol.161 No.1
<P><B>Abstract</B></P><P>To identify target genes against silver nanoparticles (AgNPs), we screened a genome-wide gene deletion library of 4843 fission yeast heterozygous mutants covering 96% of all protein encoding genes. A total of 33 targets were identified by a microarray and subsequent individual confirmation. The target pattern of AgNPs was more similar to those of AgNO<SUB>3</SUB> and H<SUB>2</SUB>O<SUB>2</SUB>, followed by Cd and As. The toxic effect of AgNPs on fission yeast was attributed to the intracellular uptake of AgNPs, followed by the subsequent release of Ag<SUP>+</SUP>, leading to the generation of reactive oxygen species (ROS). Next, we focused on the top 10 sensitive targets for further studies. As described previously, 7 nonessential targets were associated with detoxification of ROS, because their heterozygous mutants showed elevated ROS levels. Three novel essential targets were related to folate metabolism or cellular component organization, resulting in cell cycle arrest and no induction in the transcriptional level of antioxidant enzymes such as Sod1 and Gpx1 when 1 of the 2 copies was deleted. Intriguingly, <I>met</I>9 played a key role in combating AgNP-induced ROS generation via NADPH production and was also conserved in a human cell line.</P>
염증성 여드름 환자에 대한 침 치료 효과와 신체이미지 인식에 대한 연구
이아름 ( Ah Reum Lee ),이인선 ( In Seon Lee ),김송이 ( Song Yi Kim ),이향숙 ( Hyang Sook Lee ),박히준 ( Hi Joon Park ),이혜정 ( Hye Jung Lee ),채윤병 ( Youn Byoung Chae ) 경락경혈학회 2013 Korean Journal of Acupuncture Vol.30 No.2
Objectives: The purpose of this study is to evaluate the efficacy of acupuncture treatment on the inflammatory lesions and body image disturbances in patients with vulgaris acnes. Methods: Fifteen inflammatory acne patients were enrolled and treated with facial acupuncture during 4 treatment sessions. We evaluated the number of papules and nodules using the Korean Acne Grading System (KAGS). We also evaluated patients` general subjective satisfaction and objective changes of inflammatory acnes symptoms using DermaVision-pro. Moreover, we observed the skin quality-of-life scale with skindex-29 and body image disturbance questionnaire (BIDQ) as secondary outcome. Adverse events were recorded as well at every visit. Results: After 4 treatment sessions, there were significant reductions in the number of papules and nodules of the patients. We found that subjective satisfactions of patients were enhanced as well as the objective inflammatory symptoms. We also found significant improvements in the quality of life and BIDQ. No serious treatment-related adverse events were reported. Conclusions: This study demonstrated that standardized facial acupuncture were effective and safe in the treatment of facial inflammatory acnes.
Imidazole Trimer-Water Complexes in Superfluid Helium Nanodroplets: Water Stretching Modes
Ahn, Ah-Reum,Lee, Seung-Jun,Lee, Seul-Ki,Min, Ah-Reum,Kim, Yu-Sic,Jung, Hyeon-Jin,Hong, Seong-Min,Lee, Joon-Hwa,Choi, Myong-Yong,Miller, Roger E. Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.4
Identification of a New Cytotoxic Biflavanone from Selaginella doederleinii
LEE, Na-Youn,MIN, Hye-Young,LEE, Jun,NAM, Joo-Won,LEE, Yoo-Jin,HAN, Ah-Reum,Adam WIRYAWAN,Wahyu SUPRAPTO,LEE, Sang Kook,SEO, Eun-Kyoung 이화여자대학교 약학연구소 2009 藥學硏究論文集 Vol.- No.19
A new biflavanone, 2,2˝,3,3˝-tetrahydrorobustaflavone 7,4´,7˝-trimethyl ether (1) was isolated from the whole plant of Selaginella doederleinii H_(IERON). (Selaginellaceae) together with the known biflavonoid, robustaflavone 7,4´,7˝-trimethyl ether (2) as the cytotoxic constituents against the three human cancer cell lines, HCT, NCI-H358, and K562. The structure of the new compound 1 was elucidated by spectral analysis including various 1D- and 2D-NMR experiments.
Phytochemical Constituents from Salvia plebeia
Ah-Reum Han,Chao Hui Duan,Jung Noh Lee,Kwang Sik Lee,홍진태,Kun Kook Lee 한국생약학회 2010 Natural Product Sciences Vol.16 No.4
Phytochemical investigation of Salvia plebeia resulted in the isolation of nine compounds. Their structures were determined to be 6-methoxynaringenin (1), 6-methoxynaringenin-7-O-b-D-glucoside (2), hispidulin (3), homoplantaginin (4), nepetin (5), nepitrin (6), 6-hydroxyluteolin (7), caffeic acid (8) and rosmarinic acid (9) by spectroscopic analyses. 6-Methoxynaringenin (1), 6-hydroxyluteolin (7) and rosmarinic acid (9) were isolated from this plant for the first time.
Blood pressure–targeted stepwise resuscitation for hemorrhagic shock in rats
Lee, Jae Hyuk,Kim, Kyuseok,Jo, You Hwan,Kim, Min A,Lee, Kyoung-Bun,Rhee, Joong Eui,Doo, Ah-Reum,Lee, Min Ji,Park, Chan Jong,Kim, Joonghee,Chung, Heajin Lippincott Williams Wilkins, Inc. 2014 The journal of trauma and acute care surgery Vol.76 No.3
BACKGROUND: Generation of reactive oxygen species (ROS) is an important mechanism of ischemia-reperfusion injury. Abrupt reoxygenation compared with slow reoxygenation has been known to increase ROS generation. Thus, slow and stepwise reperfusion can reduce ROS generation and subsequent ischemia-reperfusion injury. This study investigated the effect of slow reperfusion by blood pressure–targeted stepwise resuscitation (PSR) in hemorrhagic shock. METHODS: Pressure-controlled hemorrhagic shock was induced in male Sprague-Dawley rats for 1 hour. Rats were then allocated to one of three groups (no-resuscitation group, n = 14; PSR group, n = 15; rapid normalization of blood pressure (RR) group, n = 15). Survival time and hemodynamic changes were recorded and compared. Blood samples and liver tissue were harvested after 6 hours of resuscitation in surviving rats. RESULTS: All of the rats in the no-resuscitation group were expired before the end of the 6-hour observation period. Survival times were significantly longer in the PSR group than in the RR group (survival rates, 11 of 15 vs. 5 of 15, log rank p = 0.032). Plasma amino alanine transferase, histologic liver injury, and ROS generation in the liver tissue were significantly lower in the PSR group than in the RR group (all findings significant, p < 0.05). In addition, PSR significantly decreased plasma nitric oxide, liver interleukin 1&bgr;, and liver interleukin 6 compared with rapid resuscitation in addition to augmenting Akt survival pathways (all p < 0.05). CONCLUSION: Slow reperfusion by PSR decreased mortality, ROS generation, and liver injury in rats undergoing hemorrhagic shock. Stepwise resuscitation also decreased inflammatory cytokine production and augmented Akt survival pathways.