ON THE ROBUSTNESS OF FORWARD MARKET EFFICIENCY IN CONSUMPTION - BASED MODELS OF EXCHANGE RATES

ARROYO Ⅲ, CRISTINO R. 한국국제경제학회 1994 International Economic Journal Vol.8 No.2

Euler equation models with consumption risk premia have shown promise of reconciling exchange rate data with the hypothesis of efficiency of the forward exchange rate. We examine the robustness of these models to variation in (1) the period utility function, (2) assumptions about the underlying forward trading mechanism, (3) the measure of consumption in the risk premium and (4) the weighting matrix applied to the model orthogonality conditions. In generalized method of moments estimations using a six-currency sample we find evidence that forward efficiency is robust to perturbations of the first two kinds, but not to the latter two. [F31, G14]

Hepatorenal Syndrome. Pathogenesis and Treatment

( Vicente Arroyo ) 대한간학회 2001 Clinical and Molecular Hepatology(대한간학회지) Vol.7 No.3(S)

Activity Participation and wellbeing during the covid-19 lockdown in Spain

Rosa Arroyo,Lidón Mars,Tomás Ruiz 서울시립대학교 도시과학연구원 2021 도시과학국제저널 Vol.25 No.3

On March 14, 2020, the Spanish authorities declared a lockdown to bending the Covid-19 pandemic curve. People were asked to stay at home as much as possible, students were obliged to attend classes on-line, civil servants were also required to tele-work, and any work activity that could be carried out from home was recommended to do so as well. Non-essential activities like theatres, restaurants, gyms, etc., were closed. Only work that could not be carried out at home, grocery shopping, taking care of others, walking the dog, visiting the doctor, do banking, and a few more out-of-home activities were allowed. Out-of-home leisure and social activities were not permitted at all. Such limitations of out-of-home activities could influence the wellbeing of people. The present study aims to analyse the wellbeing of people considering the limitations of out-of-home activities during the lockdown. Data collected through a web-survey from 1,653 participants is studied in this paper. The information analysed is related to the satisfaction of the basic psychological needs (autonomy, competence and relatedness) and positive and negative affect. Activity-travel data and sociodemographic characteristics are also considered. Mann–Whitney U tests, Confirmatory Factor Analyses and Structural Equation models are used to find out differences in the wellbeing of people according to their out-of-home activity characteristics, and how these activity characteristics are associated to the psychological variables studied. Findings suggest that those who mostly spent their out-of-home time working felt slightly better. However, as time working increased, more negative affect and autonomy frustration appeared. On the other hand, more time doing grocery shopping was associated with positive feelings. In general, women felt somewhat worse, and older participants felt a bit better during the lockdown. Employed respondents felt better than their unemployed counterparts. Some lessons are learned to improve urban planning during a pandemic. On March 14, 2020, the Spanish authorities declared a lockdown to bending the Covid-19 pandemic curve. People were asked to stay at home as much as possible, students were obliged to attend classes on-line, civil servants were also required to tele-work, and any work activity that could be carried out from home was recommended to do so as well. Non-essential activities like theatres, restaurants, gyms, etc., were closed. Only work that could not be carried out at home, grocery shopping, taking care of others, walking the dog, visiting the doctor, do banking, and a few more out-of-home activities were allowed. Out-of-home leisure and social activities were not permitted at all. Such limitations of out-of-home activities could influence the wellbeing of people. The present study aims to analyse the wellbeing of people considering the limitations of out-of-home activities during the lockdown. Data collected through a web-survey from 1,653 participants is studied in this paper. The information analysed is related to the satisfaction of the basic psychological needs (autonomy, competence and relatedness) and positive and negative affect. Activity-travel data and sociodemographic characteristics are also considered. Mann–Whitney U tests, Confirmatory Factor Analyses and Structural Equation models are used to find out differences in the wellbeing of people according to their out-of-home activity characteristics, and how these activity characteristics are associated to the psychological variables studied. Findings suggest that those who mostly spent their out-of-home time working felt slightly better. However, as time working increased, more negative affect and autonomy frustration appeared. On the other hand, more time doing grocery shopping was associated with positive feelings. In general, women felt somewhat worse, and older participants felt a bit better during the lockdown. Employed respondents felt better than their unemployed counterparts. Some lessons are learned to improve urban planning during a pandemic.

The meta-instrument as compositional technique: Strategies of the current musical creation

Alberto Arroyo(알베르토 아로요) 한국전자음악협회 2018 에밀레 Vol.16 No.-

2차 세계대전 이후 미학 패러다임의 이동은 새로운 표현의 가능성과 악기의 음색 활용에 기반한 작곡 기술의 발전을 이끌어내며 기존의 관계와 체계들을 전례없는 것들로 변화시켰다. 또한, 최근 수 년 간 선보인 테크놀로지의 역할이 완전히 새로운 어떤 것을 창조하도록 부추기며 음악을 작곡하거나 친숙한 고전 악기의 음색 변화의 가능성을 높이는 데 많은 창작자들에게 명백한 영향을 끼쳤다. 이러한 상황으로부터 출현하게 된 동일한 음악적 실제를 정의하는 새로운 용어, 메타 악기<SUB>meta-instrument</SUB>는 소리 각 부분의 총합을 초월하여 움직이며 청각적 환상을 만들어내는 자율적 소리 실체의 통합적 음색에 대한 테크닉이다. 지아친토 셸시<SUB>Giacinto Scelsi</SUB>, 헬무트 라헨만<SUB>Helmut Lachenmann</SUB>, 차야 체르노빈<SUB>Chaya Czernowin</SUB>, 마크 안드레<SUB>Mark Andre</SUB>, 호세 마리아 산체스-베르두<SUB>José María Sánchez-Verdú</SUB>, 라파엘 상도<SUB>Raphaël Cendo</SUB> 같은 작곡가들은 서로 다른 의도로 다양한 결과를 양산하며 그들의 시선을 이 테크닉으로 돌려 각각의 음악적 견해를 확고히 하였다. 더우기, 이미 몇몇 미학분야와 현재 트렌드에서 그 영향력을 선명히 드러낸 디지털 혁명이 작곡의 전통적 개념 뿐 아니라 음악 자체에 대한 생각을 재정의하거나 최소한 확장시키지 않으면 안 될 논란의 공간을 열어 놓았다. 청취하는 행위는 인간 존재의 의미와 관련한 근본적인 의문사항이니 어찌되었든 이 논의의 중심에 있다. The aesthetic paradigm shift after the Second World War inspired the emergence of new expressive possibilities and the development of compositional techniques on the timbral use of instruments, changing the relationships and hierarchies that had previously existed among them. Additionally, the role that technology has played in recent years has clearly influenced many creators when composing their music and changing the sound possibilities of familiar classic instruments while encouraging the creation of completely new ones. A new lexicon to define the same musical reality appears out of the development of these facts: the meta-instrument, a technique born from the idea of merging timbres in an autonomous entity that acts beyond the sum of its parts and produces an acoustic illusion in listening. Coming from different perspectives and yielding varying results, composers such as Giacinto Scelsi, Helmut Lachenmann, Chaya Czernowin, Mark Andre, José María Sánchez-Verdú and Raphaël Cendo have turned their gaze toward this strategy to solidify their musical thought. Moreover, the digital revolution, whose influence on some aesthetics and current trends is already apparent, has opened up a space not without controversy that seeks to redefine, or at least expand, the classic definition of composition and even the very idea of music itself. One way or another, listening is placed at the center of a debate to question, once again, the essential aspects of what it means to be human.

Synergistic Effect of Trabectedin and Olaparib Combination Regimen in Breast Cancer Cell Lines

Sonia Ávila-Arroyo,Gema Santamaría Nuñez,Luis Francisco García-Fernández,Carlos M. Galmarini 한국유방암학회 2015 Journal of breast cancer Vol.18 No.4

Purpose: Trabectedin induces synthetic lethality in tumor cells carrying defects in homologous recombinant DNA repair. We evaluated the effect of concomitant inhibition of nucleotide-excision repair and poly (ADP-ribose) polymerase (PARP) activity with trabectedin and PARP inhibitors, respectively, and whether the synthetic lethality effect had the potential for a synergistic effect in breast cancer cell lines. Additionally, we investigated if this approach remained effective in BRCA1-positive breast tumor cells. Methods: We have evaluated the in vitro synergistic effect of combinations of trabectedin and three different PARP inhibitors (veliparib, olaparib, and iniparib) in four breast cancer cell lines, each presenting a different BRCA1 genetic background. Antiproliferative activity, DNA damage, cell cycle perturbations and poly(ADP-ribosyl)ation were assessed by MTT assay, comet assay, flow cytometry and western blot, respectively. Results: The combination of trabectedin and olaparib was synergistic in all the breast cancer cell lines tested. Our data indicated that the synergy persisted regardless of the BRCA1 status of the tumor cells. Combination treatment was associated with a strong accumulation of double-stranded DNA breaks, G2/M arrest, and apoptotic cell death. Synergistic effects were not observed when trabectedin was combined with veliparib or iniparib. Conclusion: Collectively, our results indicate that the combination of trabectedin and olaparib induces an artificial synthetic lethality effect that can be used to kill breast cancer cells, independent of BRCA1 status.

β-Caryophyllene, a Dietary Cannabinoid, Protects Against Metabolic and Immune Dysregulation in a Diet-Induced Obesity Mouse Model

Noel N. Franco-Arroyo,Juan M. Viveros-Paredes,A. Sara M. Zepeda-Morales,Erika Rolda´n,Ana L. Ma´rquez-Aguirre,Jose´ S. Zepeda-Nun˜o,Gilberto Vela´zquez-Jua´rez,Mary Fafutis-Morris,Rocio I. Lo´pez-Roa 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.10

Obesity is an abnormal or excessive accumulation of fat in the body that exacerbates metabolic and inflammatory processes, and impairs the health of afflicted individuals. β-caryophyllene is a natural sesquiterpene that is a dietary cannabinoid with anti-inflammatory properties and potential activity against metabolic diseases. In the present study, we evaluated the effect of β-caryophyllene on C57BL/6 mice using a diet-induced obesity model. Male mice were randomly assigned to the following groups over a 16-week period: (1) standard diet as lean control, (2) high-fat diet (HFD) as obese control, and (3) HFD + β-caryophyllene with β-caryophyllene at 50 mg/kg. Treatment with β-caryophyllene improved various metabolic parameters including increased total body weight, fasting glucose levels, oral-glucose tolerance, insulin tolerance, fasting triglycerides, adipocyte hypertrophy, and liver macrovesicular steatosis. β-caryophyllene also modulated the levels and expression of immune response factors including adiponectin, leptin, insulin, interleukin-6, tumor necrosis factor-a, and Toll-like receptor-4. Our data indicate that chronic supplementation with β-caryophyllene can improve relevant metabolic and immunological processes in obese mice. This protocol was approved by the Institutional Committee for Care and Use of Laboratory Animals from the University of Guadalajara with protocol code CUCEI/CINV/CICUAL-01/2022.

A Survey of Routing Protocols for Maximizing the Lifetime of Ad Hoc Wireless Networks

Natalia Vassileva,Francisco Barcelo-Arroyo 보안공학연구지원센터 2008 International Journal of Software Engineering and Vol.2 No.3

The principal focus of this survey is on how to maximize the useful lifetime of ad hoc wireless networks through energy-efficient routing. Most of the studies on energy-aware routing protocols do not provide clear-cut notions about a network’s lifetime and therefore there is a lack of clear objectives in the design of algorithms. Hence, first the operational lifetime of ad hoc networks is defined. Then, published works that give solutions to energy-based problems are analysed by placing emphasis on common characteristics and drawbacks. It is aimed to reveal the factors that influence the depletion of energy in ad hoc networks. This should aid the design of energy-efficient solutions. Load balancing routing protocols are also surveyed as a means for extending a network’s operational lifespan, which is a technique that is overlooked in the literature. The immediate implications that load balancing has for energy consumption are indicated. Subsequently, a classification of load balancing routing protocols is provided along with a summary of load balancing methods that may be useful for efficient energy consumption.

Acute and Repeated 28-Day Oral Dose Toxicity Studies of Thymus vulgaris L. Essential Oil in Rats

Rojas-Armas, Juan,Arroyo-Acevedo, Jorge,Ortiz-Sanchez, Manuel,Palomino-Pacheco, Miriam,Castro-Luna, Americo,Ramos-Cevallos, Norma,Justil-Guerrero, Hugo,Hilario-Vargas, Julio,Herrera-Calderon, Oscar Korean Society of ToxicologyKorea Environmental Mu 2019 Toxicological Research Vol.35 No.3

Thymus vulgaris L. is widely used as an ingredient in cooking and in herbal medicine. However, there is little information about its toxicity. The present study was performed to evaluate the acute and repeated 28-day oral dose toxicity of thyme essential oil in rats. For the acute toxicity test, two groups of three rats were used. The rats received a single dose of essential oil: 300 or 2,000 mg/kg of body weight (bw). The rats were observed individually during the first four hours, and then daily until day 14. For the toxicity test with repeated doses, four groups of 10 rats were used. Doses of 100, 250, and 500 mg/kg/day were tested for 28 days. At the end of the experiment, blood was collected and the animals were sacrificed. Histopathological examination showed that in the lungs of rats given the 2,000 mg/kg bw dose, polymorph nuclear infiltrates, hemosiderin macrophages, and interstitial space thickening were present. In the repeated dose study, all rats survived the 28-day treatment period and apparently showed no signs of toxicity. The hematological and biochemical parameters were not altered. The histopathological study of the organs showed severe changes in the lung, with the dose of 500 mg/kg/day; in the other organs, no alterations were observed or the changes were slight. The body weight was only altered in male rats given the 500 mg/kg dose. The relative weight of the organs did not show any significant changes. Our studies revealed that the essential oil of Thymus vulgaris has moderate oral toxicity according to the results of the acute test, whereas the results of the 28-day oral toxicity test suggest that the no-observed-adverse effect level (NOAEL) is greater than 250 mg/kg/day.

Acute and Repeated 28-Day Oral Dose Toxicity Studies of Thymus vulgaris L. Essential Oil in Rats

Juan Rojas Armas,Jorge Arroyo-Acevedo,Manuel Ortiz-Sánchez,Miriam Palomino-Pacheco,Américo Castro-Luna,Norma Ramos-Cevallos,Hugo Justil-Guerrero,Julio Hilario-Vargas,Oscar Herrera-Calderón 한국독성학회 2019 Toxicological Research Vol.35 No.3

Thymus vulgaris L. is widely used as an ingredient in cooking and in herbal medicine. However, there is little information about its toxicity. The present study was performed to evaluate the acute and repeated 28-day oral dose toxicity of thyme essential oil in rats. For the acute toxicity test, two groups of three rats were used. The rats received a single dose of essential oil: 300 or 2,000 mg/kg of body weight (bw). The rats were observed individually during the first four hours, and then daily until day 14. For the toxicity test with repeated doses, four groups of 10 rats were used. Doses of 100, 250, and 500 mg/kg/day were tested for 28 days. At the end of the experiment, blood was collected and the animals were sacrificed. Histopathological examination showed that in the lungs of rats given the 2,000 mg/kg bw dose, polymorph nuclear infiltrates, hemosiderin macrophages, and interstitial space thickening were present. In the repeated dose study, all rats survived the 28-day treatment period and apparently showed no signs of toxicity. The hematological and biochemical parameters were not altered. The histopathological study of the organs showed severe changes in the lung, with the dose of 500 mg/kg/day; in the other organs, no alterations were observed or the changes were slight. The body weight was only altered in male rats given the 500 mg/kg dose. The relative weight of the organs did not show any significant changes. Our studies revealed that the essential oil of Thymus vulgaris has moderate oral toxicity according to the results of the acute test, whereas the results of the 28-day oral toxicity test suggest that the no-observed-adverse effect level (NOAEL) is greater than 250 mg/kg/day.

Maximum vortex-induced vibrations of a square prism

Barrero-Gil, A.,Fernandez-Arroyo, P. Techno-Press 2013 Wind and Structures, An International Journal (WAS Vol.17 No.1

This paper presents an experimental investigation concerning the peak amplitudes of oscillation of a square prism due to Vortex-Induced-Vibrations (VIV) as a function of the mass damping parameter $m^*{\zeta}$(the so called Griffin--plot); $m^*$ and ${\zeta}$ being, respectively, the non-dimensional mass and the mechanical (structural) damping ratio. With this purpose in mind, an electromagnetic actuator has been employed to provide controlled damping. During the experiments the mass--damping parameter was in the range 0.15 < $m^*{\zeta}$ < 2.4. Experiments show that there is a value of $m^*{\zeta}$ below which VIV appears combined with galloping and the prism oscillation increases monotonically with the incoming flow velocity. For $m^*{\zeta}$ >0.3 the present experiments show a well-defined VIV phenomenon and, consequently, a Griffin-plot can be defined.