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      • GALIS 구조 기반 실시간 분산 위치 데이타 서버 구현

        이준우,이운주,이호,나연묵,Lee, Joon-Woo,Lee, Woon-Ju,Lee, Ho,Nah, Yun-Mook 한국공간정보학회 2005 한국공간정보시스템학회 논문지 Vol.7 No.1

        LBS 시스템 분야의 도전할 만한 과제는 이동 객체를 다루는 수준부터 수백만 개의 이동 객체를 처리할 수 있는 높은 신뢰도의 시스템 아키텍처를 구현하는 것이다. GALIS로 명명된 아키텍처는 각각 다른 지리적 영역과 시간적 영역에 연관된 레코드를 유지하는 다수의 프로세서로 구성된 클러스터 기반 분산 컴퓨팅 시스템 아키텍처이다. 이 논문에서는 실시간 분산 객체 프로그래밍과 실시간 분산 컴퓨팅 시스템 디자인을 지원하는 미들웨어 실행 엔진을 포함하는 TMO 프로그래밍 기법을 적용하여 GALIS의 주요 요소를 구성하는 위치 데이타 서버의 프로토타입을 구현했다. 본 논문에서는 실질적으로 위치 측위 정보가 발생하는 과정과 이런 위치 정보와 위치 관련 질의가 어떻게 처리되는지도 기술하였다. 몇 가지 실험은 분산을 통해 프로세서의 부하를 줄여주어 성능향상이 있음을 살펴볼 수 있었다. A challenging task in the LBS system engineering is to implement a highly scalable system architecture which can manage moderate-size configurations handling thousands of moving items as well as upper-end configurations handling distributed computing system architecture that consists of multiple data processors, each dedicated to keeping records relevant to a different geographical zone and a different time zone. In this paper, we explain a prototype location data server structuring major components of GALIS by employing the TMO programming scheme, including the execution engine middleware developed to support real-time distributed object programming and real-time distributed computing system design. We present how to generate realistic location sensing reports and how to process such location reports and location-related queries. Some experimental results showing performance factors regarding distributed query processing are also explained.

      • KCI등재

        토끼의 일측 신동맥 결찰수 발생된 신경색에 있어서 확산강조영사의 유용성에 관한 연구

        이준우,김석,김용우,허진삼,최상열,문태용,이석홍,김병수,이창훈,Lee, Jun-Woo,Kim, Suck,Kim, Yong-Woo,Hu, Jin-Sam,Choi, Sang-Yoel,Moon, Tae-Yong,Lee, Suck-Hong,Kim, Byung-Su,Lee, Chang-Hun 대한영상의학회 1998 대한영상의학회지 Vol.38 No.2

        Purpose : To assess the usefulness of diffusion-weighted imaging(DWI) in evaluating serial parenchymal changesin renal infarction induced by renal artery ligation, by comparing this with the conventional spin echo techniqueand correlating the results with the histopathological findings. Materials and Methods : In 22 rabbits, renalinfarction was induced by ligation of the renal artery. Spin-echo T1-weighted imaging(T1WI), turbo spin-echo(TSE)T2-weighted imaging(T2WI), and DWI were performed, using a 1.5-T superconductive unit, at 30 minutes, 1 hour, 2,3, 6, 12 and 24 hours, and 2, 3, 7 and 20 days after left renal artery ligation. Changes in signal intensity onT1WI, T2WI, and DWI were correlated with histopathologic findings. Results : On MR images obtained 30 minutesafter ligation, the signal intensity of affected kidney was not significantly different from that of contralateralkidney, as seen on T1WI and T2WI, but was noticeably higher on DWI. On T2WI, the signal intensity ratio(SIR) wasslightly higher over time from 30 minutes to 2 days after ligation, and then decreased slightly. The SIR on DWIincreased abruptly at 30 minutes, remained high until 12 hours, and then fell, returning to close to the normalrange at between 2 and 3 days. It fell further, below the normal range, until 20 days after ligation. The mainhistopathologic findings after ligation were congestion and swelling of renal tubules (1-6 hours after ligation),degeneration and necrosis of renal tubules (12 hours - 2 days), coagulation necrosis of renal tubules(3 days),collection of cellular debris between renal tubules (7 days), and proliferation of fibroblast between renaltubules (20 days). Conclusion : Diffusion-weighted imaging is useful for the detection of hyperacute renalinfarction, and the apparent diffusion coefficient may provide additional information concerning its evolution.

      • SCOPUSKCI등재
      • KCI등재

        Chlorella pyrenoidosa의 생장 특성 및 동일 균주로부터 Acetaldehyde Dehydrogenase의 활성 검출

        이준우,Lee, June-Woo 한국미생물학회 2009 미생물학회지 Vol.45 No.4

        광합성 담수 녹조류인 Chlorella pyrenoidosa의 최적 생장 조건을 알기 위해 배양 온도, 시간, 영양물질의 영향 및 조도 등을 조사하였다. Growth chamber를 사용하여 알아본 가장 적절한 조건은 온도 $28^{\circ}C$에서 4일간 배양했을 때이며 배지에 첨가된 타 영양물질의 농도가 높을수록 활발한 광합성을 하면서 생장하였고 조도(Lux)가 크면 클 수록 잘 자랐다. 또한 동일 균주로부터 acetaldehyde를 분해하는 효소의 활성을 살펴보았는데 이 효소는 $\beta$-$NAD^+$를 조효소로 하는 탈수소효소였으며, ODS-Hypersil column과 50%(v/v) acetonitrile을 이동상으로 한 HPLC로 분석한 결과 pH 9.0, 온도 $40^{\circ}C$ 부근에서 최대 효소 활성을 보여주었다. To investigate the cellular growth traits of a photosynthetic green algae, Chlorella pyrenoidosa, several tests upon a culture temperature, a culture time, the influence of nutrient and the intensity of illumination were executed. Using growth chamber, some optimal conditions for the culture of algae were as follows: The culture temperature was about $28^{\circ}C$, the culture time about 4 days, and the cellular growth of algae was in proportioned to the concentration of nutrient such as nutrient broth. And the more the intensity of illumination was increased, the more the algal cell showed good growth. And then, the activity of enzyme degrading acetaldehyde was also studied using HPLC from the same strain. This enzyme was dependent on $\beta$-$NAD^+$. And showed its optimal pH around on 9.0, and also its optimal temperature around at $40^{\circ}C$. The operational conditions of HPLC were as follows: Column, ODS-Hypersil ; mobile phase, 50% (v/v) acetonitrile.

      • KCI등재

        수박 엘리트 계통의 GBS를 통한 마커이용 육종용 SNP 마커 개발

        이준우,손병구,최영환,강점순,이용재,제병일,박영훈,Lee, Junewoo,Son, Beunggu,Choi, Youngwhan,Kang, Jumsoon,Lee, Youngjae,Je, Byoung Il,Park, Younghoon 한국식물생명공학회 2018 식물생명공학회지 Vol.45 No.3

        본 연구는 국내 육종 회사에서 개발된 수박(Citrullus lanatus L.) 우량 육성계통 20종을 대상으로 Genotyping-by-sequencing(GBS) 분석을 통해 품종식별, 순도검정, 그리고 마커이용여교잡(Marker-assisted backcross, MABC)용 SNP 세트를 개발하고자 수행되었다. GBS 분석 결과 총 1,100,000천개 raw read 중 77%가 수박 유전체에 mapping되었으며 평균 mapping region은 약 4,000 Kb로 2.3%의 genome coverage를 보였다. Filtering을 통해 평균 depth 31.57의 SNP 총 2,670개를 얻었으며, 20개 계통에 대한 이들의 Polymorphic information content(PIC) 값의 범위는 0.1 ~ 0.38 였다. 이 중 PIC 값이0.3이상이며 각 염색체 별로 5개씩 균등히 분포된 SNP 총 55개를 최종 선발하였다. 사용된 20개 계통의 유연관계분석을 위해 선발된 55개 SNP를 기반으로 한 주성분 분석(Principle component analysis, PCA) 결과 주성분 1 (52%)과 주성분 2 (11%)를 기준으로 4개의 그룹으로 분류 되었으며 각 계통 간 유전자형에 따른 뚜렷한 식별이 가능하였다. 계층적 군집화(Hierarchical clustering) 분석에서도PCA에서와 유사한 분류양상을 관찰할 수 있었다. 따라서 본 연구에서 개발된 SNP 세트는 적용 가능성이 검증된 20개 계통뿐 만 아니라 향후 다양한 수박 육종소재 및 품종에 대한 품종식별, F1 순도검정 및 MABC에 활용될 수 있으리라 기대된다. This study was conducted to develop an SNP set that can be useful for marker-assisted breeding (MAB) in watermelon (Citrullus. lanatus L) using Genotyping-by-sequencing (GBS) analysis of 20 commercial elite watermelon inbreds. The result of GBS showed that 77% of approximately 1.1 billion raw reads were mapped on the watermelon genome with an average mapping region of about 4,000 Kb, which indicated genome coverage of 2.3%. After the filtering process, a total of 2,670 SNPs with an average depth of 31.57 and the PIC (Polymorphic Information Content) value of 0.1~0.38 for 20 elite inbreds were obtained. Among those SNPs, 55 SNPs (5 SNPs per chromosome that are equally distributed on each chromosome) were selected. For the understanding genetic relationship of 20 elite inbreds, PCA (Principal Component Analysis) was carried out with 55 SNPs, which resulted in the classification of inbreds into 4 groups based on PC1 (52%) and PC2 (11%), thus causing differentiation between the inbreds. A similar classification pattern for PCA was observed from hierarchical clustering analysis. The SNP set developed in this study has the potential for application to cultivar identification, F1 seed purity test, and marker-assisted backcross (MABC) not only for 20 elite inbreds but also for diverse resources for watermelon breeding.

      • KCI등재

        소아 환자에서 조직확장기 사용의 유용성

        이준우,박철규,박종림,김용규,Lee, Jun-Woo,Park, Chul-Gyoo,Park, Jong-Lim,Kim, Yong-Kyu 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.6

        Purpose: Reconstruction of soft tissue defect using tissue expander can provide better flap which is more similar to surrounding tissue in color, skin texture and hair compared to other methods. Many pediatric patients need reconstruction of soft tissue defect because of giant congenital nevi, congenital or acquired malformations and burn scars. Reconstruction using tissue expander is adequate to minimize dysmorphism in these patients. We intended to assess outcomes of using tissue expander in pediatric patients by retrospective study. Methods: Total cases were 168 of pediatric patients who received soft tissue reconstruction using tissue expander by the same surgeon from February, 1982 to May, 2009. All patients who received soft tissue reconstruction were under 10 years old. Mean age was 4.3 years old, the youngest 13 months, the oldest 8 years. Eightynine cases were male and 79 cases were female. Most common cause was giant hairy nevi (67 cases, 39.9%), secondary cause was burn scar/scar contracture (61 cases, 36.3%). Trunk (38 cases, 22.6%) was most common anatomical location. Results: Soft tissue defects were successfully covered using tissue expander in 149 cases (88.7%) without major complications. There was infection on 8 cases (4.7%) and we treated by adequate antibiotics in these cases. There were tissue expander folding or valve displacement on 5 cases (3%). Conclusion: Usage of tissue expander is useful on pediatric patients because tissue expansion is rapid on children and there are less secondary contractures on operation site than full thickness skin graft. Because of psychological stress due to tissue expander, operation should be performed before school age.

      • KCI등재

        임도공사시 굴삭기를 이용한 토공작업의 공정분석

        이준우,박범진 ( Joon Woo Lee,Bum Jin Park ) 한국산림과학회 1998 한국산림과학회지 Vol.87 No.1

        This study was carried out to investigate working time, performance, and to predict performance that related to the factor of forest road in earth work using excavator. It was found that the real working time was 503 minutes in a day. The ratio of real working time and allowance per total working time was approximately 85.7% and 14.3% individually. The rate of soil movement(Sm) to net working time was 38.6%, and earth cutting(Ec) was 32.5% . According to performance analysis, performance of earth work using excavator(0.8㎥) in straight part was 1.4 times larger than curve part and rock work using excavator(0.8㎥) which had breaker in straight was 9.1 times larger than earth work using excavator(0.8㎥) which had bucket. Performance of earth work using excavator(1.0㎥) was 1.3 times larger than using excavator(0.8㎥) in straight and curve part. Working performance in earth work using excavator(0.8㎥) was influenced by the conditions of radius of curve, width of roadway, slope gradient. It is not influenced by diameter and number of root stock.

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