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문경 현리 전통주택 및 현대주택의 방위 및 배치특성 연구
윤선옥(Yun Sun-Ok),곽동엽(Kwak Dong-Yeob) 대한건축학회 2007 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.27 No.1
The purpose of this study is ratiocinates the element which gives an effect to formation of traditional village in Korea and proposes a change direction. This work is executed by the introduction of the next process. (①Currently investigation of the feature which appears, ②Analysis of the condition which is considered on the Modernization process and the quality which is continued.) Consequently with change of the physical and technical side and the residents pursue traditionally the change which originates from change of the cultural belief in the village effect, there was a possibility of going mad and as new element it considered. The object of research it is Hyun-ri village in Mun-kyung. That village has from process of modernization and it is because the character which the character and the past traditional village have coexists. This study is composed of two major parts. First part is preceding literature research. Based on the results of the first part, the second part is on-the-spot inspection and two branches which precede it analyzed a quality with character. If there is not a standard to process of the change in compliance with an if modernization the traditional village will lose a regional true identity characteristic. The research against the change quality of the traditional village from like this point suggests a desirable direction with the fact that it will be the possibility of role in the harmony of tradition and modernization comes to seem.
CD40L 발현 K562 세포주를 이용한 시험관내 B 세포 증식과 항원제공능 증가
박정용,윤성희,김은경,윤선옥,손현정,김태규,Park, Jung-Yong,Yoon, Sung-Hee,Kim, Eun-Kyung,Yun, Sun-Ok,Sohn, Hyun-Jung,Kim, Tai-Gyu 대한면역학회 2007 Immune Network Vol.7 No.2
Background: CD40-activated B (CD40-B) cells might be an attractive source of autologous antigen-presenting cells (APCs) for immunotherapy due to the convenience to obtain from peripheral blood and expand in vitro. Moreover, CD40-B cells were found to be comparable with DCs in their capacity to raise antigen-specific CD8+ T cells. Here, we have established K562 cells expressing CD40L to expand CD40-activated B cells used for APCs. Methods: After activation of B cell by K562/CD40L, CD40-B cells were examined by counting B cell numbers. Surface expression of CD54, CD80, CD86 and HLA class II was measured by flow cytometry. The CD40-B cells were tested for its function as APC by mixed lymphocyte reactions (MLR) and by induction of T cell responses specific for pp65 peptide in vitro. Results: The expansion of B cells by K562/CD40L increased about 6-folds compared with anti-CD40 or K562. Furthermore, the expression of CD54, CD80, CD86 and HLA class II was up-regulated by K562/CD40L. B cells by K562/CD40L showed comparable antigen presentation activity with mature DCs as shown in MLR, INF-${\gamma}$ ELISPOT assay. Conclusion: These results suggest that K562/CD40L could be used to generate activated B cells as potent APCs which could be useful for cellular vaccination and adoptive immunotherapy.
정미혜,윤선옥,박정희,추순옥,오소영,김미영 병원간호사회 2011 임상간호연구 Vol.17 No.3
Purpose: The purpose of this study was to investigate the predictors of delirium in patients after orthopedic surgery. Methods: Participants were 121 orthopedic surgery patients from one university affiliated hospital located in Seoul. The instrument of Delirium Observation Screening Scale (DOS) developed by Schuurmans et al. (2003) was utilized. Data were collected from September 1st, 2010 to March 31st, 2011 and analyzed using SPSS 12.0 with descriptive statistics, t-test, chi-square test and logistic regression. Results: The delirium in patients after orthopedic surgery was occurred in 9 (7.4%) out of 121 patients. Several factors were associated with the delirium occurrence age, admission route, preadmission Activity of Daily Living (ADL), preadmission hearing aid use, preadmission walking degree, diagnosis, type of surgery, Intensive Care Unit (ICU) stay after surgery, restraint, drainage tube, time of admission to surgery, preoperative albumin and preoperative sodium. Preadmission ADL, preoperative sodium and time of admission to surgery were the significant predictors of the delirium occurrence. Conclusion: Study results may help nurses predicting and detecting delirium early and providing preventive measures to the patients with high risk of delirium after orthopedic surgery.