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박한수,서영호,최두선,제태진,황경현,Park, Han-Su,Seo, Yeong-Ho,Choe, Du-Seon,Je, Tae-Jin,Hwang, Gyeong-Hyeon 한국기계연구원 2003 硏究論文集 Vol.33 No.-
The automatic assembly system of micro optical filter is a key technology in the development of optical modules with high functionality. In order to create such automatic assembly system of optical filter, we have developed the system and program capable of evaluation of $30\mum$-thick film optical filter as well as conventional optical filters performances. Moreover, we have carried out the evaluation of optical filter using developed system and program, and we have compared and analyzed them with by conventional hand work. As results, the measured performances based on the present system are more fast, precise and reliable then those of the conventional hand work. In addition to that, the system can apply for various optical collimators and filters.
군신좌사 개념을 도입한 방제 검색 및 비교 시스템에 관한 연구
박한수,이병욱,이부균,Park, Hansu,Lee, ByungWook,Lee, Boo-Kyun 대한한의학방제학회 2014 大韓韓醫學方劑學會誌 Vol.22 No.2
Objectives : The main objective of this study is to classify herbal components to 4 groups which are similar to Gunsinjwasa grades by using herbal composition ratio of prescription. Another objective is to design the searching system which compares prescriptions and improves efficiency with 4 groups like Gunsinjwasa grades. Methods : This study was proceeded with Acess 2007 on Microsoft Windows 7 and we created composition ratio based on weight by using prescriptions of Donguibogam, Uihagipmun and Banghakhabpyun. We could make comparison and searching method of prescriptions. Results : We could search using composition ratio degree of herbs which composes prescription. And the similarity comparison of prescription was possible with value from 0 to 10. Conclusions : We could increase the accuracy of the searching prescriptions and comparison with putting into the information about composition degree and composition ratio of herbs which compose a prescription.
박한수,김승희,김부영,장일무,Park, Han-Soo,Kim, Seung-Hee,Kim, Pu-Young,Chang, Il-Moo The Korean Society of Toxicology Korea Environment 1990 Toxicological Research Vol.6 No.1
Aconiti Tuber is the root of Aconitum sp (Ranunclaceae) which has been considered as one of the most important medicinal plant having cordiotonic, diuretic and analgesic effect. On the other hand, it has been known that Aconiti Tuber contained toxic agent, aconitine alkaloids so that only processed Aconiti Tubers have been used as herbal drug traditionally. For the safety evaluation of processed Aconiti Tuber, quantitative determination of aconitine and acute, subacute toxicity test were performed on 5 commercial processed Aconiti Tubers. Arapid and precise method using HPLC has been developed for the separation and determination of aconitine. Samples were extracted with hydrochloric acid (pH3) and hot water decoction. In case of d-HCL extracts, the contents of aconitine were from 0.08 mg/g to trace. But in case of hot water decoction extracts, the contents of aconitine were not detected. For the investigation of Aconiti Tuber toxicity in rats, hot water decoction samples and methanol extracts were tested. 1) Acute toxicity test Hot water decoction sample and methanol extracts from Aconiti Tuber did not show any toxic effects in rats by an oral administration. $LD_50values of 2 extracts were above 10.0 g/kg. 2) Subacute toxicity study In the repeated administration study, hot water decoction samples were given orally to Sprague-Dawlay rats for 2 week at daily doses of 5.0 g/kg. The results are as follows; No toxic manifestation, body weight changes and lethality were observed during wxperimental period. There were no significant changes in serum enzyme activities such as GOT, GPT, LDH, ALP between treated and control groups. However CPK values were decreased in the Subuja-treated group. (P<0.01). In addition, no gross and microscopic changes were noted in Aconiti Tuber-treated groups.