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박세라(Park, Se-Ra),이예지(Lee, Ye-Ji),신동규(Shin, Dong-Kyu) 대한건축학회 2021 대한건축학회 학술발표대회 논문집 Vol.41 No.2
The purpose of this study was to design for an stay type museum in Daegu-city where is the important place of Korean modern literiture. This conceptural design aim to plan a new spaces for creative activities and to promote communicate and cooperate with neighborhood residents and literary person who stay in literature museum.
국내 중진 지역 특성에 따른 인공지진파 생성에 대한 연구
박세라 ( Park Se-ra ),박영빈 ( Park Young-bin ),김승현 ( Kim Seung-hyun ) 한국구조물진단유지관리공학회 2022 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.26 No.1
국내 중진 발생 빈도가 높아짐에 따라 국내 특성을 고려한 지진파형을 분석하여 목표 스펙트럼에 매칭하였으며, 내진설계 기준에 부합하는 한국형 인공지진파를 생성하였다.
선소 해역 부근의 해양 환경 개선 사업 고찰 및 주민들의 환경 인식 조사에 대한 연구
심왕근(Wang Geun Shim),박세라(Se Ra Park),김상채(Sang Chai Kim) 한국환경교육학회 2009 環境 敎育 Vol.22 No.1
The relationship between marine environmental improvement and environmental perception of the inhabitants was investigated. For this purpose, the seawater and bottom materials were analysed. Apart from this, the questionnaire surveys were also conducted around the Sun-so coastal area. In order to examine the improvement in the marine environment, 12 monitoring sites, which are located around Sun-so coast and can be divided into two parts such as inland (GW1-GW6) and outland (GW7-GW12) sea, were chosen. All the collected samples were analyzed to find out the quality of seawater (temperature, pH, salinity, dissolved oxygen: DO, chemical oxygen demand: COD and suspend solid: SS), nutrients (total nitrogen: TN and phosphate: PO₄-P) and bottom materials (COD, volatile solids: VS) as per the standard analytical procedures. In addition, the questionnaire mainly focused on the following three factors: 1) social economy, 2) dependent environmental awareness and 3) independent environmental awareness related with the environmental education. The monitoring studies indicated that the marine environment of the Sun-so coast showed various trends for analyzing parameter. No significant temporal changes in temperature, pH and salinity were observed. However, the other parameters showed decreasing (COD, SS, TN, PO₄-P and VS) and increasing (DO) trends according to the quality of seawater and bottom materials. The questionnaire survey clearly showed that most of the residents in Sun-so recognized the improvement of marine environment as compared with the situation experienced in the past. The dredging project which is closely related with economic and living conditions of the local residents led to alter the environmental perceptions and attitudes. The survey also indicated that the inhabitants perceived the necessity of the environmental education (87% of respondents) and preferred regular schooling (55% of respondents) as effective and practical education methods.
돌연변이 p53 단백질의 Silencing에 의한 사람유방암세포의 in vivo 항종양 효과
박원익(Won Ick Park),박세라(Se-Ra Park),박현주(Hyun-Joo Park),배윤희(Yun-Hee Bae),유현수(Hyun Su Ryu),장혜옥(Hye-Ock Jang),배문경(Moon-Kyoung Bae),배수경(Soo-Kyung Bae) 한국생물공학회 2016 KSBB Journal Vol.31 No.1
Mutant p53 (R280K) is highly expressed in MDAMB-231 triple-negative human breast cancer cells. Currently, we reported the role of mutant p53-R280K in mediating the survival of MDA-MB-231 cells in vitro. The present study was undertaken to determine whether mutant p53-R280K affects breast cancer cell growth in vivo. To this end, we used small interfering RNA to knockdown the level of mutant p53- R280K in MDA-MB-231 cells. Silencing of mutant p53- R280K in MDA-MB-231 cells causes substantial tumor regression of established xenografts in vivo. In xenograft model for breast cancer, silencing of mutant p53-R280K in MDAMB-231 cells significantly inhibited the tumor growth. Moreover, TUNEL assay showed more occurrence of apoptotic cells in mutant p53-R280K silenced tumors compared to control. Our data indicate that mutant p53-R280K has an important role in mediating tumor growth of MDA-MB-231 cells in vivo. Taken together, this study suggests that endogenous mutant p53-R280K could be used as a therapeutic target for breast cancer cells harboring this TP53 missense mutation.
소뇌교각 거미막낭에 대한 수술로 회복된 일측성 돌발성 난청
성한경(Han Kyung Sung),고범준(Bum Jun Ko),신승훈(Seung-Hun Sheen),박세라(Se Ra Park) 대한두개저학회 2017 대한두개저학회지 Vol.12 No.1
Sudden sensorineural hearing loss(SSNHL) is a common clinical disease in otolaryngology. In many cases, the causes of sudden hearing loss cannot be determined, but a cerebello-pontine angle (CPA) mass, such as an arachnoid cyst, is one of them. Arachnoid cysts are usually asymptomaic; however, when they have mass-effect, they may present with symptoms such as dizziness, tinnitus and hearing loss. The authors report a case of a 63 year-old male who presented with sudden hearing loss linked to a CPA arachnoid cyst. The patient underwent a retromastoid suboccipital craniotomy with fenestration of the arachnoid cyst to get rid of his neurological symptoms and hearing loss which did not respond to medical treatments. After the surgery the patient s hearing was recovered and other symptoms disappeared.
Web3D의 정보전달 방법에 관한 연구 : Web3D를 이용한 전자상거래에서 정보전달방법을 중심으로
박세라,이동윤,이진영 동서대학교부설연구센터 2001 연구센터논문집 Vol.4 No.1
As the development of the computing technology and the expansion of networking, the way of transmitting information has been changed from two dimension to three dimension. Specially, it has been changes rapidly on the internet. In two dimensional environment uses simply get texts and 2D images, but now we can get information dynamically and really through three dimensional environment. The paper shows the definition and features of Web3D representing 3D technology on the web. We also discuss about E-Commerce on Web3D and actually test the feature of Web3D.