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갑상선 유두암의 외측 경부림프절 전이에 대한 수술 전 평가로서 CT의 역할
석준걸(Jungirl Seok),김형규(Hyung gu Kim),김윤중(Yoonjoong Kim),한규희(Kyu-Hee Han),안순현(Soon-Hyun Ahn) 대한두경부종양학회 2013 대한두경부 종양학회지 Vol.29 No.2
Background and Objectives:To assess the usefulness of computed tomography image before papillary thy-roid cancer surgery, focus on confirmation of lateral cervical lymph node metastasis not detected by ultrasonogra-phy. Material and Methods:From January 2008 to May 2009, total 150 patients who had undergone thyroid sur-gery and been confirmed papillary thyroid cancer pathologically were enrolled. They had taken neck computed tomography following the ultrasonography. Results:Computed tomography had found suspicious metastatic lat-eral neck lesion in 13 patients. After the image study, lateral neck lymph node dissection had been included in their surgical plan. Of these, only 7 cases were confirmed pathologically lateral neck lymph node metastasis(positive predictive value=0.54). Taken as whole 150 patients, additionally 4.7% of patients confirmed lateral neck lymph node metastasis by preoperative computed tomography. Conclusion:If preoperative ultrasonography was per-formed precisely, additional benefits that could be achieved by computed tomography were not much.
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유영(You Young),김형규(Kim Hyung-Gu),박세진(Park Se-Jin) 한국해양환경·에너지학회 2007 한국해양환경·에너지학회 학술대회논문집 Vol.2007 No.-
1977년 12월 31일 제정된 해양오염방지법은 2007년 1월 19일 해양환경관리법 공포와 함께 폐지되었다. 본 논문은 해양환경관리법상에서의 주요 신설 및 보완된 내용들과 기존 해양오염방지법과의 차이점을 현장집행업무 중심으로 비교ㆍ검토하였다. 신법에서는 해양환경의 종합관리를 위한 ‘국가의 기본원칙’과 환경정책을 종합적ㆍ체계적으로 추진할 수 있는 법적근거를 마련하였으며, 오염방제를 효과적으로 추진할 수 있도록 해양경찰청장으로 하여금 국가긴급방제계획을 수립ㆍ시행토록 명문화하였다. 해양환경보호를 위한 해역 이용협의의 의무화와 해양환경관리공단 신설 등 깨끗하고 안전한 해양환경 조성을 위한 해양환경관리체계 개편을 주요 골자로 하고 있다. Marine Pollution Prevention Law, legislated in Dec. 1977, was abrogated when Marine Environmental Management Law was enacted and promulgated at 19 Jan. 2007. This present study is aimed to review the new complementary provisions of Marine Environmental Management Law that are different from Marine Pollution Prevention Law, especially focus on execution procedures of law in field. The New Law contains ’the principal of National policy’ for the Comprehensive Marine Environmental Management. It is a legal basis on promoting systematically the Integrated National Marine Environmental Management Plan. In behalf of effective responding to marine pollution, this law delegates the commissioner general of Korea Coast Guard to establish and enforce the National Contingency Plan. It also compel to take counsel with government before utilization of sea area and found the Marine Environmental Management Corporation for the clean and safe marine environment.
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실험적 급성 허혈성 신부전에서 Verapamil 이 혈중 Polyamine 동태에 미치는 영향
원동준(Dong Jun Won),권현민(Hyun Min Kwon),김용섭(Yong Seop Kim),구자룡(Ja Ryong Gu),권영주(Young Ju Kwon),조원용(Won Yong Cho),김형규(Hyung Kyu Kim) 대한내과학회 1991 대한내과학회지 Vol.40 No.6
N/A It has been proposd that calcium entry from an external medium increases intracellular free calcium to toxic levels during ischemic acute renal failure, and verapamil (ARF) has been suggested as the agentblocking calicium entry into renal cells and protecting renal function during ischemic injury. Polyamines, anorganic cations that play various roles in normal cellular proliferation and differentiation, accumulate in renal failare. Alsa it has been suggested tht the synthesis and metabolism of polyamine are influence by acute changes of the general condition, such as acute renal failure, and are mediated by a calcium influx into the cells. The study was designed to study the protective effects of systemic verapamil pretreatment on renal function and the influence on polyamine metabolism in experimental ischemic ARF in cats. For these purpose, the experimental animals were divided into 2 groups. While Group I (n=5) was an ischemic ARF model by renal artery clamping for 60 minutes, Group II (n=5) was ischemic ARF with systemic verapamil (5 ml/min/kg) pretreatment. The creatinine clearance and plasma and urinary polyamine were measured in each group before and after the renal artery clamp. The results were as follows: 1) Creatinine clearance before and after the renal artery clamp were 10.64±7.18 ml/min/kg and 2.09±1. 70 ml/min/kg in Group I, 4.47±3.38 ml min/kg and 0.60±0.79ml/min/kg in Group II, respectively, So creatinine clearance decreased more significantly in Group II campared with Group I. 2) Plasma polyamine increased after ischemia in Group I. In group I, plasma levels of putrescine, spermidine, and spermine before ischemia were 4.75±0.40 nmol/ml, 0.69±0.09 nmol/ml, and 0.83±0.63 nmol/ml, were elevated to 7.17±2.91 nmol/ml, 9.83±1.46 nmol/ ml, and 2.64±1.14nmol/ml after ischemia. But in Group II, the plasma level of polyamine was not changed, and especially, spermine decreased significantly from 0.83±0.27 before ischemia to 0.49±0.23 nmol/ml after ischenmine (p=0.033). 3) Urine polyamine excretion decreased after ischemia in Group I and Group II. In Group II, urinary excretion of spermidine and spermine before ischemia, 0.13±0.10 nmol/min and 0.17±0.13nmol/min, decreased after ischemia to 0.01±0.01nmol/min (p=0.019) and 0.032±0.26 nmol/min (p=0.0257). 4) In renal tissue, spermine content vas highest. In Group II, preischemic spermine were 397.20 nmol/g and increased to 646.66nmol/g after ischema, But there were no significant changes in the polyamine contents in Group II. From these data, it was suggested that systemic verapamil pretreatment exerts no protective effect on ischemic ARF. Plasma polyamines are elevated in ischemic ARF, and verapamil may protect these elevations.
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