경골 골절후 발생한 족부 변형들의 분석 및 치료 결과에 대한 분석

김정렬,김영신,신성진,김상림,서규범,Kim, Jung-Ryul,Kim, Young-Sin,Shin, Sung-Jin,Kim, Sang-Rim,Seo, Kyu-Bum 대한족부족관절학회 2009 대한족부족관절학회지 Vol.13 No.2

Purpose: We wanted to evaluate the relating factors for deformities of the foot after tibial fracture and the outcome of respective surgical treatment. Materials and Methods: We studied thirty-two patients (thirty-five feet) who had foot deformities after tibia fracture. The age, gender, shape, location, concurrent soft tissue injury and operative treatment of tibial fracture were analysed and outcome of the surgical treatment was investigated. Results: Deformities of the foot mostly occurred in open fractures of Gustilo type 3 or closed fracture with severe soft tissue injury. Variable surgical treatments such as simple release, lengthening, Z-plasty and osteotomy were performed. The AOFAS ankle-hind foot scale was improved from average of 37.3 points preoperatively to an average of 77.2 points at the last follow up. The Maryland foot score was from 42.9 to 90.2 and AOFAS Lesser Toe Metatarso-phalangeal interphalangeal scale was from 42.9 to 90.5. Radiological correction was also improved from 21.9 degrees to 7.9 degrees (Meary angle), from 112.2 to 138.5 (Hibb's angle) and from 33.8 to 25.9 (Calcaneal pitch). Conclusion: We proposed that great care should be taken of treatment for the tibial fracture and early detection and proper management of the foot deformities are crucial.

건율제조탕이 CCl₄로 유발(誘發)된 간손상(肝損傷) 백서(白鼠)에 미치는 영향(影響)

김정렬,김혁,양상묵,김달래,전종원,Kim, Jung-Yul,Kim, Hyuk,Yang, Sang-Mook,Kim, Dal-Rae,Jeon, Jong-Weon 사상체질의학회 2004 사상체질의학회지 Vol.16 No.3

1. Objectives This study was carried out to investigate the effects of Gunyuljejo-tang on the $CCl_4$-induced Liver Damage in Rats. 2. Methods Sprague-Dawley rats were devided into 5 experimental groups : Normal, $NS+CCl_4$(Solid extract of $CCl_4$ injection group after Normal Saline feed), $GYJJT+CCl_4$(Solid extract of $CCl_4$ injection group after Gunyuljejo-tang feed), $CCl_4+NS$(Normal Saline feed group after $CCl_4$ injection), $CCl_4+GYJJT$(Solid extract of Gunyuljejo-tang feed group after $CCl_4$ injection). Biochemical assays for serum enzyme activities such as AST, ALT, ALP, BUN, Creatinine, Uric Acid, Total Protein, Albumin, Total Cholesterol, Triglyceride, Glucose, and mRNA Revelation of Cytochrome p450 and activities such as LPO, GSH, GST, Glutathione Reductase, Glutathione Peroxidase, SOD, Catalase, Hydroxyproline, and ${\beta}$-Glucuronidase were performed. 3. Results (1) $GYJJT+CCl_4$ showed lower revelation of Cytochrome p450. (2) $GYJJT+CCl_4$ showed higher GSH activity than $NS+CCl_4$, $CCl_4+GYJJT$ showed higher GSH activity than $CCl_4+NS$ injection significantly. (3) $GYJJT+CCl_4$ showed higher GST activity than $NS+CCl_4$. $CCl_4+GYJJT$ showed higher GST activity than $CCl_4+NS$ significantly. (4) $GYJJT+CCl_4$ showed higher Glutathione Peroxidase activity than $NS+CCl_4$, $CCl_4+GYJJT$ showed higher Glutathione Peroxidase activity than $CCl_4+NS$ significantly. (5) $CCl_4+GYJJT$ showed higher SOD activity than $CCl_4+NS$ significantly. (6) $CCl_4+GYJJT$ showed higher Catalase activity than $CCl_4+NS$ significantly. (7) $GYJJT+CCl_4$ showed lower Hydroxyproline than $NS+CCl_4$ significantly, $CCl_4+GYJJT$ showed higher Hydroxyproline than $CCl_4+NS$ significantly. (8) $GYJJT+CCl_4$ showed higher ${\beta}$-Glucuronidase activity than $NS+CCl_4$, $CCl_4+GYJJT$ showed higher ${\beta}$-Glucuronidase activity than $CCl_4+NS$ significantly. 4. Conclusions Gunyuljejo-tang has the recovering effects on the $CCl_4$-induced Liver Damage significantly.

저산소증에 의한 활막 섬유모세포의 ICAM-1 발현에 대한 항산화제의 영향

김정렬,류완희,Kim, Jung Ryul,Yoo, Wan Hee 대한면역학회 2002 Immune Network Vol.2 No.1

Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial hyperplasia and joint destruction. The synovial fibroblasts express cell adhesion molecules and have a role in adhesive interation with inflammatory cells in synovial tissue. It has been suggested that hypoxic conditioins are thought to exist in arthritic joints, and several studies indicate that reactive oxygen species (ROS) produced in hypoxic condition can initiate events that lead to pro-adhesive changes via increased expression of adhesion molecules. So, this study wsa designed to examine whether antioxidant can inhibit hypoxia-induced expression of ICAM-1 in cultured human synovial fibroblasts. Methods: Synovial fibroblasts were isolated from synovial tissue in patients with RA and cultured at hypoxic condition. Antioxidant, PDTC (pyrrolidine dithiocarbamate) were pre-treated for an hour before the hypoxic culture and synovial fibroblasts were harvested at 0, 6, 12, 24, 48 hours time points. Cell surface ICAM-1 expression in synovial fibroblasts was examined by the flow cytometric analysis. To analyse the expression of ICAM-1 mRNA, reverse-transcriptase polymerase chain reaction (RT-PCR) was performed. The levels of cytokines in culture supernatants were measured by ELISA, and activation of NF-${\kappa}B$ was analysed by electrophoretic mobility shift assay. The adhesive reaction between synovial fibroblasts and lymphocytes was assayed by measurement of fluorescent intensity of BCECF-AM in lymphocytes. Results: Hypoxic stimuli up-regulated the ICAM-1 expression as well as the adhesive interaction of human synvial fibroblasts to lymphocytes in a time-dependent manner, and PDTC inhibited hpyoxia-induced ICAM-1 expression and cell-cell interaction. PDTC also inhibited the hypoxia-induced activation of intracellular transcription factor, NF-${\kappa}B$. PDTC decreased the amount of hypoxia-induced production of IL-$1{\beta}$ and TNF-${\alpha}$. Conclusion: These studies demonstrate that PDTC inhibit the hypoxia-induced expression of the adhesion molecule, ICAM-1 and activation of NF-${\kappa}B$ in cultured human synovial fibroblasts.

북한 중학교 영어교과서 대화문에 나타난 상황과 의사소통 기능 분석

김정렬(Kim, Jeong-ryeol) 한국영어교과교육학회 2021 영어교과교육 Vol.20 No.2

The main purpose of this paper is to analyze situations and communicative functions appeared in the dialogues of the 2013 North Korean middle school English textbooks. Situation analysis includes places of the dialogues, social and psychological relationships among the participants of the dialogues. Communicative functions include social functions, transactional functions and others which cannot be categorized into either category. Three qualified analyzers participated in the analysis and their concurrence rate index α was 0.89. The findings are: Situation analysis indicated that places, dialogue participants and their relationships are restricted to the schools and classrooms among friends, teacher and family members with a few exceptions. Communicative functions indicated that present or past event inquiry and answers outweigh over all the other communicative functions. A few structural practice and content-based lessons also appear in the textbooks across different grades. The analysis result indicates that North Korean English textbooks became an outlier of CLT (communicative language teaching) English textbooks in efforts of incorporating three Kims’ dictates on English language teaching.

전완 원위부 심 수지 굴근에 발생한 선천성 혈관 외피세포종 - 증례 보고 -

김정렬,장규윤,이상용,Kim, Jung-Ryul,Jang, Kyu-Yun,Lee, Sang-Yong The Korean Musculoskeletal Tumor Society 2007 대한골관절종양학회지 Vol.13 No.2

혈관 외피 세포종은 드문 악성 혈관 종양으로 대부분 성인에서 발생한다. 영아에서 발생하는 경우는 선천성 또는 영아형 혈관 주변 세포종이라 불리우며, 아주 드물게 발생하고 성인형에 비해 양호한 예후를 보이지만 재발을 막기 위해서는 충분한 절제연을 가지고 절제 되어져야 한다. 본 증례는 출생후 1일째 내원하여, 65일째 광범위 절제술을 시행한 좌측 전완부의 혈관 외피 세포종의 증례를 보고하고자 한다. Hemangiopericytoma is a rare malignant vascular tumor that usually occurs in adults. The occurrence of these tumors in infants, known as congenital or infantile hemangiopericytoma, is even rare and their behavior may be more benign than the adult type. Despite of the generally good prognosis associated with this neoplasm, a complete surgical excision has so far been recommended to avoid recurrence, because no definite criteria for determining whether or not the tumor will regress spontaneously have been established to date. We describe a 1-day-old male neonate with congenital hemangiopericytoma, presenting with a left forearm mass at birth. Wide resection was performed at 65 days of age and hemangiopericytoma was diagnosed by histology. There was no tumor recurrence during 32 months of follow-up.

도로면 크랙실링(균열보수)을 위한 자동화 장비 개발연구

김정렬,조문영,Kim, Jeong-Ryeol,Jo, Mun-Yeong 한국건설관리학회 2003 건설관리 : 한국건설관리학회 학회지 Vol.4 No.1

건설생산성 향상을 위한 사업관리 기술 (Management Practices) 개발 및 컴퓨터 비전 (Computer Vision) 활용 연구 동향

김정렬,Kim, Jeong-Ryeol 한국건설관리학회 2014 건설관리 : 한국건설관리학회 학회지 Vol.15 No.1

계측기(計測器)를 이용(利用)한 O-Ring Test법(法)의 검증(檢證)에 관(關)한 연구(硏究)

김정렬,김달래,Kim, Jong-Ryol,Kim, Dal-Rae 사상체질의학회 1995 사상체질의학회지 Vol.7 No.1

Using Bi-Digital O-Ring Test which was developed by Ohmura Toshiaki, constitution classification by the vegetables' was measured by various muscle power measurement meters and the results are as follow : 1. Pinch guage (Model : pc5030HPG, Japan) is the guage to measure finger power between the thumb and second finger, Grip Strength Dynamometer (Model : T.K.K. 5101, Japan) is to measure the hand power (hand dynamometer), Back Strength dynamometer (Model : T.K.K. 5102, Japan)is to measue back muscle strength, Vertical Jump Meter (Model : T.K.K. 5106, Japan) is to measure the height of jump. The above guages were used and its result found that the radish, potato, carrot and cucumber can influence to the muscle strength was not true. 2. When the physical constitution is distinguished vy the O-Ring Test method, Taeyangin's rate appeared as average 21% although it was insistedthat there will be only 0.03-0.1%. This means that the influence power of vegetable doest not appear according to the physical constitution but it appears accidently according to the examinee's emotion about the material such as vegetable etc. as favor or unfavor. 3. It was found that the result of O-Ring Test is the same at any time and at any place was not true. there is no reemergence character. 4. The import of O-Ring Test method to the physical discriminatio disregarded that the mental facor influences absolutely to the physical heath in the ideological physical constitution medicla science. 5. 'O-Ring Test method is a objective judgement method'. is wrong judgement. As you see on the above result, Bi-Digital O-Ring Test set the changeable voluntary muscle as the standard of the judgement, that was first mistake logically, second in spite of leass influence of mental influence by the examiner and examinee than the vegetable discrimination influence, the test disregarded the influence. Thire, only grasp of some material on hand can influence to the voluntary was a wrong theory disregarding the physiology. Finally the misunderstaning his subjective view as an objective view in spite of examiner and examinee's strong influence. Therefore such kind of physical descrimination method must be sublated.

기획특집-G4팩시밀리 개발현황과 향후시장

김정렬,Kim, Jeong-Ryeol 한국전자정보통신산업진흥회 1992 電子振興 Vol.12 No.4

경골 근위부에 발생한 거대세포형 골육종 - 증례 보고 -

김정렬,장규윤,이상용,손경락,Kim, Jung-Ryul,Jang, Kyu-Yun,Lee, Sang-Yong,Sohn, Kyung-Rak 대한근골격종양학회 2006 대한골관절종양학회지 Vol.12 No.2

거대세포형 골육종은 드문 종양으로 거대세포종과의 구분이 어렵다. 이들 종양은 발생 부위 및 방사선학적 소견이 동일하다. 또한 이들 종양의 조직학적 소견도 구분이 어렵다. 이들 두 종양의 서로 다른 예후와 치료 방법 때문에 처음 진단시 반드시 정확한 진단을 내려야 한다. 본 논문은 처음 진단 당시 침생검에 의해 거대세포종으로 진단되었던 경골 근위부의 거대세포형 골육종의 증례를 보고하는 바이다. Giant cell-rich osteosarcoma is a rare tumor that is hard to distinguish from giant cell tumors of bone. The location and radiographic aspect of these tumors can be identical. The histologic differentiation between a giant cell-rich osteosarcoma and a giant cell tumor can be difficult. Due to the different prognosis and treatment strategies of these tumors it is essential to make the right diagnosis at presentation. This article reports a case of a giant cell-rich osteosarcoma of the proximal tibia that initially was diagnosed histologically as a giant cell tumor by needle biopsy.