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강홍규 ( Hong Kyu Kang ),백진옥 ( Jin Ok Baek ),노주영 ( Joo Young Roh ),이종록 ( Jong Rok Lee ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.7
Background: Melasma is an acquired, symmetrical hypermelanosis that occurs on sun-exposed areas of the skin. It has significant emotional and psychological effects on those affected with the condition. Melasma Quality of Life Scale (MELASQOL) is a specific questionnaire to identify the most impaired areas of melasma patient`s life. Objective: Our purpose of this study is to investigate the changing of MELASQOL after the treatment of melasma. Methods: A total of 27 volunteers with melasma were enrolled in this 8-week treatment study. The patients were instructed to apply an arbutin-containing cream, <at a frequency of> once a day for 8 weeks. The assessment of outcomes included the colorimetric value (L*) and MELASQOL score. Results: The arbutin-containing cream group increased more in the colorimetric values (L*) after the 8-week treatment (p<0.01). The MELASQOL score was decreased (p=0.02). No significant adverse reactions were observed. Conclusion: The treatment of melasma improves the QOL of melasma patients. (Korean J Dermatol 2012;50(7): 579∼583)
전신성 홍반성 루푸스의 첫 증상으로 발생한 Sweet 증후군
강홍규 ( Hong Kyu Kang ),손영민 ( Young Min Son ),나소영 ( So Young Na ),이혜영 ( Hye Young Lee ),백진옥 ( Jin Ok Baek ),노주영 ( Joo Young Roh ),이종록 ( Jong Rok Lee ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.1
Sweet syndrome is also called acute febrile neutrophilic dermatosis and this malady is characterized by an abrupt onset of fever, leukocytosis and tender erythematous plaques that are infiltrated by neutrophils. It most commonly occurs in women who are between 30 to 50 years of age. About 50% of the cases are associated with autoimmune disease, sarcoidosis, Behcet`s disease and pregnancy. We present here a 48-year-old woman who had tender erythematous tender plaque and nodules with vesicles and pustules over both extremities. She complained of general weakness, chills and arthralgia. We biopsied the nodule and performed laboratory tests. The results of the biopsy were compatible with Sweet syndrome and the laboratory test showed systemic lupus erythematosus. We report here on a case of Sweet syndrome as an initial presentation of systemic lupus erythematosus. (Korean J Dermatol 2010;48(1):43∼46)
강홍규 ( Hong Kyu Kang ),곡원호 ( Howard Chu ),김도영 ( Do Young Kim ) 대한피부과학회 2016 대한피부과학회지 Vol.54 No.8
Cryotherapy is one of the most widely used procedures in the field of dermatology. Since the development of cryotherapy with the use of liquid nitrogen beginning in the 19th century, its use has gradually increased for various dermatologic conditions, including benign conditions, premalignant lesions, and malignancies. Because the therapeutic effects of cryotherapy are diverse, it must be applied specifically for each indication, requiring a thorough understanding of the basic principles and mechanisms of cryotherapy. In addition, both acute and chronic complications can develop, which may possibly leave permanent scars and tissue damage, thus, careful manipulation is required. In conclusion, cryotherapy is a frequently used treatment method but should be performed precisely by well-trained specialists. (Korean J Dermatol 2016;54(8):595∼600)
각질가시세포종 양상으로 나타난 전이된 악성 섬유조직구종
강홍규 ( Hong Kyu Kang ),손영민 ( Young Min Son ),나소영 ( So Young Na ),이혜영 ( Hye Young Lee ),백진옥 ( Jin Ok Baek ),노주영 ( Joo Young Roh ),이종록 ( Jong Rok Lee ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.11
Malignant fibrous histiocytoma (MFH) has been considered to be the most common malignant soft tissue tumor of middle and late adulthood. This tumor is usually a skin-colored subcutaneous nodule. It metastasizes to the lung, lymph node, bone and liver. Metastasis to the skin is very rare. We present a case of a 69-year-old man who presented with an asymptomatic dome-shaped large nodule with central umbilical ulceration on his scalp that had grown abruptly over 3 months. The lesion clinically mimicked keratoacanthoma. Biopsy of the nodule was done to differentiate keratoacanthoma from MFH confirmed the latter. The result of biopsy was MFH. Diagnosis was MFH of unknown primary tumor origin. We report a case of metastatic MFH mimicking keratoacanthoma. (Korean J Dermatol 2009;47(11):1275~1279)
강홍규 ( Hong Kyu Kang ),백진옥 ( Jin Ok Baek ),이종록 ( Jong Rok Lee ),노주영 ( Joo Young Roh ) 대한피부과학회 2012 大韓皮膚科學會誌 Vol.50 No.2
Background: Genetic predisposition and environmental aspects may act as triggering factors and influence the disease expression. Dong-gu, which is located on the west of Incheon, has a large harbor and industrial complex. Such environmental aspects of Dong-gu may play a role in AD. Objective: We investigated the epidemiologic features of AD in preschool and elementary school children in Dong-gu. Methods: This study was carried out among 2,760 preschool and elementary school children from June to October. A questionnaire survey is composed of clinical manifestations, genetic and environment factors and lifestyle. Two dermatologists examined the skin conditions of the subjects. The severity of AD was evaluated using the Eczema Area and Severity Index (EASI) score and the factors affecting the severity of the diseases were determined. Results: The questionnaire suggested that there was 19.7% of the preschool childhood and elementary school students in Incheon with AD. But, the prevalence of AD evaluated by the two dermatologists was 13.2%. The average EASI score is 2.88 (±4.08). There was a statistical significance in parental past history, especially of atopic dermatitis and moving into a new house within a year after birth (p<0.05). Conclusion: These results suggest that there is strong correlation of genetic and environmental factors in the severity of atopic dermatitis in children. (Korean J Dermatol 2012;50(2):114~122)
웅성불임 및 왜성형질의 제초제저항성 들잔디(zoysia japonica Steud.)의 판별기술 개발
이범규(Bum kyu Lee),강홍규(Hong-Gyu Kang),라누리(Nu ri Ra),선현진(Hyeon-Jin Sun),권용익(Yong-Ik Kwon),송인자(In-Ja Song),김창기(Chang-Gi Kim),류태훈(Tae-Hun Ryu),박기웅(Kee Woong Park),이효연(Hyo-Yeon Lee) 충남대학교 농업과학연구소 2014 농업과학연구 Vol.41 No.3
The cultivation area and use of genetically modified (GM) crops have been increased continuously over the world. Concerns about the potential risks of GM crops are also increasing. Safe management for the development and production of GM crops is required according to Living Modified Organism Act in Korea. Planning about the methods, duration, and frequency of environmental monitoring is also required for commercial use of GM crops. GM Zoysia japonica Steud. (event name: JG21) expressing resistance to glufosinate-ammonium has been generated previously. By using gamma ray treatment to JG21 we also developed male sterility and dwarf Z. japonica (event name: JG21-MS). The objective of this study was to establish the monitoring system for environment release of JG21-MS. In this study we extracted RNA from JG21 and JG21-MS and conducted RAPD (random amplified polymorphic DNA) method to distinguish JG21 and JG21-MS.
손영민 ( Young Min Son ),강홍규 ( Hong Kyu Kang ),나소영 ( So Young Na ),이혜영 ( Hye Young Lee ),백진옥 ( Jin Ok Baek ),노주영 ( Joo Young Roh ),이종록 ( Jong Rok Lee ),김유진 ( Yu Jin Kim ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.8
Pilomatricoma is a common benign neoplasm that originates from the matrix of the hair root. The tumor usually presents as a deep-seated, solitary, firm nodule with overlying epidermis. It occurs more frequently in the head and neck region of children and adolescents, and it often involves the eyelid or eyebrow. Pilomatricoma is often misdiagnosed clinically and the correct diagnosis can be established only after excision and histological examination. The pathologic diagnosis of pilomatricoma is based on finding large masses of shadow cells, combined with basophilic cells, inflammation, foreign body giant cells, calcification and ossification. We report here on 3 cases of pilomatricoma that clinically presented as hemangioma on the eyelid. Punch and excisional biopsy were done after ultrasonography, and we diagnosed the lesions as eyelid pilomatricoma. (Korean J Dermatol 2009;47(8):951~955)