Learning Probabilistic Kernel from Latent Dirichlet Allocation

( Qi Lv ),( Lin Pang ),( Xiong Li ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.6

Measuring the similarity of given samples is a key problem of recognition, clustering, retrieval and related applications. A number of works, e.g. kernel method and metric learning, have been contributed to this problem. The challenge of similarity learning is to find a similarity robust to intra-class variance and simultaneously selective to inter-class characteristic. We observed that, the similarity measure can be improved if the data distribution and hidden semantic information are exploited in a more sophisticated way. In this paper, we propose a similarity learning approach for retrieval and recognition. The approach, termed as LDA-FEK, derives free energy kernel (FEK) from Latent Dirichlet Allocation (LDA). First, it trains LDA and constructs kernel using the parameters and variables of the trained model. Then, the unknown kernel parameters are learned by a discriminative learning approach. The main contributions of the proposed method are twofold: (1) the method is computationally efficient and scalable since the parameters in kernel are determined in a staged way; (2) the method exploits data distribution and semantic level hidden information by means of LDA. To evaluate the performance of LDA-FEK, we apply it for image retrieval over two data sets and for text categorization on four popular data sets. The results show the competitive performance of our method.

Diagnosis Value of Membrane Glycolipids Biochemistry Index in Intracranial and Gastrointestinal Tumors

Lv, Jun,Lv, Can-Qun,Mei, Ping,Qi, Shi-Mei Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

The diagnostic value of membrane glycolipid biochemistry index, the lipid-bound sialic acid (LSA) and total sialic acid (TSA) in cerebrospinal fluid (CSF) was evaluated in 30 intracranial and 65 gastrointestinal tumors. The plasma LSA, TSA and red cell membrane sialic acid (R-SA) in were determined according to the method of Sevenmerhulm. Our results showed that the levels of LSA and TSA in CSF of intracranial tumor patients was higher than that of normal group(p<0.01). The concentration of TSA and LSA in patients with malignant glioma was higher than that of benign meningioma patients(P<0.01). No significance was found between intracranial halmatoma patients and normal control group for levels of membrane glycolipids (p>0.05). Results also found that the plasma LSA, TSA and R-SA of gastric carcinoma were significantly higher than those of control group (p<0.05); while no significant difference was found in the plasma LSA, TSA and R-SA levels between chronic gastritis, gastrohelcoma and normal control group (p>0.05). Plasma LSA, TSA and R-SA levels of gastric carcinoma patient were significantly higher than those of chronic gastritis patients and gastrohelcoma patients(p<0.05). It was also found that plasma LSA, TSA and R-SA contents were significantly higher in large intestine carcinoma patients than in benign in stestine tumor patients (p<0.05) while no significant difference was found between intestine benign tumor and normal control group (p>0.05). The levels of LSA, TSA and R-SA were obviously higher in the patients with metastasis than in the ones without (p<0.05.) The membrane glycolipid biochemistry index LSA and TSA in CSF are sensive markers for diagnosing intracranial tumors. For gastrointestinal malignant tumors the plasma LSA TSA and red blood cell membrane SA may be considered as auxiliary indicators for diagnosis. They can be used for distinguishing benign from malignant tumors.

Inhibition of microRNA-214 promotes epithelial mesenchymal transition process and induces interstitial cystitis in postmenopausal women by upregulating Mfn2

Jian-Wei Lv,Wei Wen,Chen Jiang,Qi-Bo Fu,Yin-Jun Gu,Ting-Ting Lv,Zhen-Dong Li,Wei Xue 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-

Our study aims to investigate the roles that microRNA-214 (miR-214) plays in the epithelial mesenchymal transition (EMT) process and the development of interstitial cystitis (IC) in postmenopausal women by targeting Mitofusin 2 (Mfn2). IC bladder tissues and adjacent normal bladder tissues were collected from postmenopausal women. Immunohistochemistry (IHC) staining was conducted. The target relationship between miR-214 and Mfn2 was determined by a dual luciferase reporter gene assay. Adipose-derived mesenchymal stem cells (ADMSCs) were extracted from postmenopausal rats and assigned to the blank, mimics, miR-214 inhibitors, mimics negative control (NC), inhibitors NC, Mfn2 siRNA, miR-214 inhibitors and Mfn2 siRNA groups. Exosomes secreted by transfected ADMSCs were instilled into the bladders of postmenopausal rats. The expression of miR-214 and Mfn2 mRNA and EMT markers was assessed by qRT-PCR and western blotting. It was confirmed that Mfn2 was the target gene of miR-214 in IC. Compared with the normal bladder tissues, miR-214 decreased, but Mfn2 increased in IC bladder tissues. Compared with the blank group, the expression of miR-214 and the expression levels of N-cadherin, Fibronectin, Twist1, Snail and Vimentin mRNA and protein increased, whereas the expression levels of Mfn2, E-cadherin and ZO-1 mRNA and protein decreased in the miR-214 mimics and Mfn2 groups. The expression of MiR-214 and the expression levels of N-cadherin, Fibronectin, Twist1, Snail and Vimentin mRNA and protein decreased, whereas the expression levels of Mfn2, E-cadherin and ZO-1 mRNA and protein increased in the miR-214 inhibitors group. Our findings indicate that the inhibition of miR-214 promotes the EMT process and contributes to bladder wall fibrosis by up-regulating Mfn2, thus leading to the occurrence of IC in postmenopausal women.

한반도 식생의 녹색화에 대한 시계열적 분석

Lv, Guan Ting,ZHUYONGYAN,Liu, Wei Qi,Huang, Xiao,Li, Cheng Lei,Cui, Gui Shan 한국기후변화학회 2019 한국기후변화학회지 Vol.10 No.4

The vegetation is feedback on environmental change due to global warming. Also, the growth status of vegetation and the coverage area of vegetation are greatly affected by the environmental changes. The quantitative change of vegetation growth status is the primary task of vegetation response to environmental changes. In this study, the Global Inventory Modeling and Mapping Studies (GIMMS) based Normalized Difference Vegetation Index (NDVI) and CRU climate data are used to analyze the spatio‐temporal characteristics of vegetation greening evolution and its response to climate change from 1982 to 2015 in the Korean Peninsula by applying the partial correlation and trend analysis. The results show that the average NDVI value of the Korean Peninsula in the period 1982‐2015 was 0.68, among which the average NDVI in North Korea and South Korea was 0.69 and 0.67, respectively. The NDVI of the Korean Peninsula between 1982 and 2015 increased by 0.6x10‐3 year‐1. The increasing trend prior to and after 1998 was 2.5×10‐3 year‐1 and 0.9×10‐3 year‐1, respectively. During the 1982‐2015 years, the NDVI of DPRK and South Korea have grown mainly with the trend of 0.2×10‐3 year‐1 and 1.1×10‐3 year‐1, respectively. According to the analysis of NDVI and climatic factors, the distribution of NDVI in the three‐time series of Korean Peninsula is consistent in spatial distribution. According to the results of partial correlation analysis of climate factor and NDVI distribution in Korean Peninsula, the region has significant partial correlation with temperature change. The climate factor of temperature is the main driver of NDVI change, which plays a key role in controlling NDVI change accumulation.

Study on the Reduction of Gear Whine Noise in Diesel Engine Gear Train

Qi Zhang(장기),Yong Bo Wang(왕용보),Jian Hua Lv(려건화),Zhong Gang Zhu(주중강),Zhen Qin(진진),Sung Ki Lyu(류성기) Korean Society for Precision Engineering 2019 한국정밀공학회지 Vol.36 No.9

Silane coupling agent assisting dopamine‑functionalized biomass porous carbons for enhanced adsorption of organic acids: effects of acid–alkali activation on microstructure

Qi Wang,Yaying Lv,Tao Zhu 한국탄소학회 2021 Carbon Letters Vol.31 No.1

Biomass porous carbons derived from Laminaria japonica were prepared by KOH and H3PO4 activation methods, respectively. The results indicated that the chemical activation had an apparent effect on the molecular framework and space of materials. To enhance the selective adsorption for organic acids, biomass carbons were modified by dopamine combined with N-(2-aminoethyl)-3-aminopropyltrimethoxysilane. The SEM and BET results illustrated the effect of the chemical activation approach on the morphology and porous texture. The biomass porous carbon using KOH activation method had the highest surface area (up to 1558 m2/ g). Compared with unmodified materials, the modified materials showed higher adsorption capacity for organic acids (27.90 μg/mL for chlorogenic acid and 25.47 μg/mL for caffeic acid). It was suggested that modification of porous carbons might be a viable pathway to increase the specific adsorption affinity and efficiency for organic acids in dried jujube samples.

Simulation and Experimental Analysis for Noise Reduction of a Scooter Gearbox

Qi Zhang(장기),Jing Zhang(장정),Zhong Hua Liu(유충화),Jian Hua Lv(려건화),Zhen Qin(진진),Sung Ki Lyu(류성기) Korean Society for Precision Engineering 2018 한국정밀공학회지 Vol.35 No.8

Enhanced separation for paraffin wax using CO2-responsive emulsions based on switchable hydrophilicity solvents

Jie Qi,Xiaojiang Li,Xin Lv,Yang Ge,Jinyu Wang,Hongsheng Lu 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.110 No.-

Wax precipitation leads to destructive harms in the exploitation and transportation of petroleum. Solventtreatments can remove paraffin wax easily but the separation of solvent relying on distillation is admittedinefficient. Aiming at enhancing the separation and recovery performance of paraffin wax, CO2-responsive emulsion (SHS/W emulsion) based on switchable hydrophilicity solvents (SHS) is adopted. Since the paraffin wax is dissolved, emulsified, and dispersed by SHS/W emulsion, SHS/W emulsion exhibitsbetter removal performance than SHS. The paraffin wax is recovered effectively upon introducingCO2, which attributes to the transformation of SHS from hydrophobic to hydrophilic state. Comparedwith the SHS system, the recovery of paraffin wax is improved obviously by introducing surfactantSpan80. Owing to the deprotonation of SHS by bubbling N2 and heating, 77.6% SHS is recycled after recoveringparaffin wax. Here, the recycled SHS can be used to realize the removal of paraffin wax again. Thus,it is a promising and alternative strategy for realizing the sustainable and rapid removal of paraffin wax inthe petroleum industry.

Clinical Characteristics and Survival Analysis of Breast Cancer Molecular Subtypes with Hepatic Metastases

Ge, Qi-Dong,Lv, Ning,Kong, Ya-Nan,Xie, Xin-Hua,He, Ni,Xie, Xiao-Ming,Wei, Wei-Dong Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

Background: The liver is one of the most common metastatic sites of breast cancer, hepatic metastases developing in 6%-25% of patients with breast cancer and being associated with a poor prognosis. The aim of this study was to analyze the survival and clinical characteristics of patients with hepatic metastases from breast cancer of different molecular subtypes and to investigate the prognostic and predictive factors that effect clinical outcome. Methods: We retrospectively studied the charts of 104 patients with breast cancer hepatic metastases diagnosed at Sun Yat-sen University Cancer Center from December 1990 to June 2009. Subtypes were defined as luminal A, luminal B, human epidermal growth factor receptor 2 (HER2) enriched, triple-negative (TN). Prognostic factor correlations with clinical features and treatment approaches were assessed at the diagnosis of hepatic metastases. Results: The median survival time was 16.0 months, and the one-, two- three-, four-, five-year survival rates were 63.5%, 31.7%, 15.6%, 10.8%, and 5.4%, respectively. Median survival periods after hepatic metastases were 19.3 months (luminal A), 13.3 months (luminal B), 18.9 months (HER2-enriched), and 16.1 months (TN, P=0.11). In multivariate analysis, a 2 year-interval from initial diagnosis to hepatic metastasis, treatment with endocrine therapy, and surgery were independent prognostic factors. Endocrine therapy could improve the survival of luminal subtypes (P=0.004) and was a favorable prognostic factor (median survival 23.4 months vs. 13.8 months, respectively, P=0.011). Luminal A group of patients treated with endocrine therapy did significantly better than the Luminal A group of patients treated without endocrine therapy (median survival of 48.9 vs. 13.8 months, P=0.003). Conclusions: Breast cancer subtypes were not associated with survival after hepatic metastases. Endocrine therapy was a significantly favorable treatment for patients with luminal subtype.

Push-out tests on stud shear connectors with constrained structure of steel-concrete composite beams

Jingjing Qi,Zuwei Xie,Hua Cao,Zhi Huang,Weirong Lv,Weihua Shi 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.83 No.6

The stud shear connector is the main force transfer member in the steel-concrete composite member, and the mechanical behavior is very complicated in the concrete. The concrete around the stud is subjected to the pry-out local pressure concentration of the stud, which can easily produce splitting mirco-cracks. In order to solve the problem of pry-out local splitting of stud shear connector, a kind of stud shear connector with constraint measure is proposed in this paper. Through the push-out test, the interface shear behavior of the new stud shear connector between steel and concrete flange plate was studied, and the difference between the new stud shear connector and the traditional stud connector was compared. The results show that the stud shear connector with constraint measure can effectively avoid the adverse effect of local pressure splitting by relying on its own constraint measure. The shear stiffness of the interface between steel and concrete flange plates is greatly improved, which provides a theoretical basis for the design of strong connection coefficient of steel-concrete composite structures.