조갑진균증 환자에서 항진균제 투여에 따른 조갑 성장 속도의 변화

여광열,김정수,김재홍,유희준 대한의진균학회 2003 대한의진균학회지 Vol.8 No.4

안 합병증으로 실명을 동반한 아토피 피부염 1예

여광열,박정환,김정수,노영석 대한피부과학회 2003 대한피부과학회지 Vol.41 No.9

Long?standing atopic dermatitis Patient frequently predispose to ocular complications such as blepharitis, keratoconjunctivitis, uveitis, cataract, and retinal detachment. Among these, cataract and retinal detachment are the most serious complications that may cause visual disturbance. Glaucoma has not been reported as the complication of atopic dermatitis, but it is believed that long-term use of topical corticosteroid on face may cause glaucoma. A 26-year-old nan presented with generalized severe atopic dermatitis and gradual loss of vision in both eyes. Because of eczema involving the skin of the face including the eyelids, he had been applying various topical corticosteroids since he was 4 years old. Eight years ago, cataracts developed on both eyes and extracapsular cataract extraction and intraocular lens implantation were done. Ophthalmologic examination revealed that his intraocular pressures were 46mmHg right and 38mmHg left, suggesting glaucoma. Three months following presentation, the patient became totally blind in both eyes. (Korean J Dermatol 2003;41(9) : 1253~1255)

대상포진 환자에서 동반되는 통증과 환자의 우울, 불안 증상의 상관성에 관한 연구

사공찬 ( Chan Sagong ),여광열 ( Kwang Yeoll Yeo ),김정수 ( Joung Soo Kim ),유희준 ( Hee Joon Yu ),김대호 ( Dae Ho Kim ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.4

Background: Acute and persistent pain are the most significant clinical manifestations of herpes zoster. It has been suggested that the demographic and clinical characteristics of patients with herpes zoster at the time of presentation predict the duration and severity of pain on long-term follow-up. However, the association between pain in herpes zoster and emotional factors such as depression and anxiety has been less well investigated. Objective: The purpose of this study was to correlate the characteristics of pain with clinical, demographic, and emotional factors in herpes zoster patients. Methods: Ninety-seven patients with herpes zoster and 105 healthy controls were recruited from the department of dermatology at a university-affiliated hospital. Depression and anxiety levels were assessed using the Beck Depression Inventory and Beck Anxiety Inventory. We compared severity of initial pain and duration of pain by age, depression, and anxiety. Results: The levels of depression and anxiety were higher in herpes zoster patients compared to controls (p<0.05). There were no significant differences by age, depression, or anxiety. The duration of pain increased with increasing age, depression, and anxiety (p<0.05). Stratified analyses showed that the association between pain duration and increasing depression and anxiety was significant in the young age group (p<0.05), but not significant in the old age group. Conclusion: This study suggests that age, depression, and anxiety are the main correlates of pain duration in patients with herpes zoster. Therefore, depression and anxiety should not be ignored in the management of herpes zoster patients. (Korean J Dermatol 2009;47(4):403~410)

부신피질 호르몬 병변내 주입으로 호전을 보인 소방성 혈관종 2예

권혁만,여광열,황동규,유희준 대한피부과학회 2002 대한피부과학회지 Vol.40 No.7

Tufted angioma is a rare, acquired vascular tumor, most commonly presenting in the first year of life, which was first described by Wilson Jones in 1979. Spontaneous resolution of this tumor are known to be very rare and local recurrence often occurs unless the tumor is excised completely. We present two cases of tufted angioma developed in two 1-year-old girls. Skin biopsy in a case showed compatible findings with tufted angioma and the other was diagnosed at an other hospital. The lesions were treated with intralesional injections of triamcinolone acetonide and showed marked improvement. During follow up period, the lesions kept improving.

Case Report : A Case of Herpetiform Appearance of Digital Mucous Cysts

( Jae Hur ),( Yong Seok Kim ),( Kwang Yeoll Yeo ),( Joung Soo Kim ),( Hee Joon Yu ) 대한피부과학회 2010 Annals of Dermatology Vol.22 No.2

A digital mucous cyst (DMC) is clinically characterized by a round to oval, translucent, smooth nodule localized to the dorsal aspect of the distal digits near the distal interphalangeal joint. It usually presents as a solitary lesion, and multiple lesions are uncommon. An 88-year-old man presented with herpetiform translucent papules on the right thumb. We first diagnosed the lesion Fig. 1. Several small, round to oval, shiny, dome-shaped, whitish papules presenting as herpetiform lesions on the right thumb.as molluscum contagiosum or herpetic whitlow. Histopathology showed a cystic space containing mucinous material and numerous fibroblasts surrounded by mucinous stroma in the upper dermis. The lining of the cyst wall was not apparent and mucinous material was stained with Alcian blue, indicating a diagnosis of DMC. (Ann Dermatol 22(2) 194~195, 2010)

Case Report : A Case of Myopericytoma on the Lower Leg

( Jun Oh Paek ),( Ho Song Kang ),( Kwang Yeoll Yeo ),( Hee Joon Yu ),( Joung Soo Kim ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.2

Myopericytoma (MP) is a benign tumor composed of cells that show apparent differentiation towards putative perivascular myoid cells called myopericytes. It arises most commonly in the dermis or subcutaneous tissue of the extremities in adults. The most common presentation is a well-circumscribed, slow-growing painless firm mass. A 45-year-old woman presented with a 2-year history of a painless, slowly growing 0.9×0.7 cm sized firm mass in the subcutaneous tissue of the posterior side of the right lower leg. We presumed this lesion to be an epidermal cyst, pilomatricoma or calcinosis cutis and performed an excisional biopsy. The histologic examination showed that it was composed of spindle-shaped myoid-appearing cells in a concentric arrangement, intimately associated with thin-walled vascular channels. Lesional spindle cells were diffusely positive for smooth muscle actin and were negative for CD34, desmin and S100 protein. From these findings, we diagnosed this lesion as a myopericytoma. (Ann Dermatol 23(2) 201∼204, 2011)

Case Report : A Case of Hereditary Hemorrhagic Telangiectasia

Ha Eun Lee,Chan Sagong,Kwang Yeoll Yeo,Joo Yeon Ko,Joung Soo Kim,Hee Joon Yu 대한피부과학회 2009 Annals of Dermatology Vol.21 No.2

Hereditary hemorrhagic telangiectasia, also known as Osler-Weber-Rendu disease, is an autosomal dominant disorder of the fibrovascular tissue. It is characterized by the classic triad of mucocutaneous telangiectasias, recurrent hemorrhages, and familial occurrence. The cutaneous manifestation appear clinically as punctuate, linear, or splinter-like telangiectasias of the upper body, oral, and nasal mucous membranes, and nail beds. A 73-year-old woman presented with purpuric, punctuate, and tiny macules on the finger tips of both hands and the tongue. The skin lesions were discovered about 50 years previously. She had a family history of cutaneous telangiectasia. Also, she had episodes of recurrent epistaxis, gastrointestinal bleeding, and anemia. The gastroendoscopy revealed gastric angiodysplasia of the fundus and body of the stomach. The histopathologic study showed dilated capillaries lined by flat endothelial cells in the papillary dermis. From these findings, we diagnosed this case as hereditary hemorrhagic telangiectasia, which has rarely been reported in the dermatologic literature. (Ann Dermatol 21(2) 206~208, 2009)

Case Report : A Case of Pigmented Bowen`s Disease

Jung Woo Lee,Jae Hur,Kwang Yeoll Yeo,Hee Joon Yu,Joung Soo Kim 대한피부과학회 2009 Annals of Dermatology Vol.21 No.2

Pigmented Bowen`s disease is characterized by increased melanin pigment in the epidermis or papillary dermis, in addition to the typical findings of Bowen`s disease. This disorder has been infrequently reported and it represents less than 2% of all cases of Bowen`s disease. Thus far, there has been only 1 case of pigmented Bowen`s disease on the umbilicus in the medical literature, and no such case has been reported in Korea. Pigmented Bowen`s disease develops on sun-exposed areas of the face and neck, as well as sun-un-exposed areas like the trunk, extremities, perianal area and umbilcus. A 36-year-old man presented with a 9-month history of solitary dark brown slithery or wavy plaque with a verrucous surface on the umbilicus, and the lesion measured 1x2 cm in size. The histopathologic findings showed hyperkeratosis, parakeratosis and atypical keratinocytes disorderly arranged throughout the epidermis. Increased melanin pigment was noted in the basal layer of the epidermis. From these findings, we diagnosed this lesion as pigmented Bowen`s disease. (Ann Dermatol 21(2) 197~199, 2009)

Pentoxifylline으로 치료한 Kaposi 육종

주민숙 ( Mihn Sook Jue ),찬사공 ( Sa Gong Chan ),여광열 ( Kwang Yeoll Yeo ),김정수 ( Joung Soo Kim ),유희준 ( Hee Joon Yu ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.7

Kaposi sarcoma is a lympho-angioproliferative disease of the skin and viscera. Because the natural history of Kaposi sarcoma is variable, the assessment of therapy may be difficult and optimal therapy has yet to be determined. Pentoxifylline has been used to treat various dermatologic diseases, but its effectiveness in Kaposi sarcoma has not been reported. We now report a case of Kaposi sarcoma in a 76-year-old man who improved after treatment with oral pentoxifylline. (Korean J Dermatol 2009;47(7):811~814)

Churg - Strauss 증후군 1 예

황동규,유희준,권혁만,여광열 대한피부과학회 2002 大韓皮膚科學會誌 Vol.40 No.1

Churg-Strauss syndrome is a clinicopathologic disorder of severe asthma, fever, and eosinophilia together with systemic vasculitis involving various organ systems. Characteristic cutaneous lesions include erythematous maculopapules resembling erythema multiforme, hemorrhagic lesions, and cutaneous and subcutaneous nodules. Histologically, extravascular granuloma and leukocytoclastic vasculitis are the most common findings. We report a case of 40-year-old woman who presented with generalized multiple hemorrhagic bullae that had developed 1 month ago. Previously, She had allergic rhinitis and asthma. Laboratory studies revealed peripheral blood eosinophilia, and positive p-ANCA. Skin biopsy revealed eosinophilic infiltrates and leukocytoclastic vasculitis.