가교화 쌀 전분의 이화학적 특성

최현욱,정구민,김정호,문태화,박천석,백무열 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.26 No.1

巴戟天의 實驗的 硏究(第1報)

최정화,홍석,정현우 대한본초학회 1996 大韓本草學會誌 Vol.11 No.1

These studies were carried out to investigate the effect of Radix Morindae water extract on the inhibitory contractile action of histamine in guinea pig. The results of these studies were as follows; 1. Contractile force of histamine from trachea smooth muscle in guinea pig was inhibited by Radix Morindae. 2. Radix Morindae did not changed the contractile force of histamine pretreated propranolol, indomethacin, and methylene blue. 3. Contractile force of uterus in rat was inhibited by Radix Morindae. 4. Contractile frequence of uterus in rat was inhibited by Radix Morindae.

제1요수 불완전 하반신 마비 환자에서의 기능적 전기자극에 의한 훈련 증례보고

최현주,이수영,김종문,강선화,정순열,강곤,정진상 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Functional electrical stimulation(FES) is known to increase muscle bulk and strength and prevent muscle atrophy in complete paraplegic patients. And other benefits include peripheral adaptations which improve muscle endurance, girth, and appearance, as well as central circulatory adaptation which enhances aerobic(cardiopulmonary) capacity. Good candidates for FES include spinal cord injured patients who have clinically complete upper motor neuron lesion between T4-T12. But we experienced incomplete L1 paraplegic patient who has improved maximal knee extension power, endurance, circumference and cross-sectional area of the thigh and the shank after FES-induced exercise for 44 weeks. So we recommend more trial of the FES-induced exercise to not only complete but also incomplete lumbar paraplegic patients.

우리나라 산재보험의 정신질환 인정실태

최경숙,이현주,김세진,이창화 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.3

Objectives : The purpose of this study was to determine characteristics of work-related psychiatric injuries with Korean Workers' compensation data. Methods : We analyzed the distribution of sex, age, types of work-related psychiatric disorders, type of industry and occupation. Using the data of 3175 Korean workers' compensation cases who were compensated for work-related psychiatric injuries from 2001 to 2003. Results : Work-related psychiatric injuries have increased annually. 897 cases, 1099 cases and 1179 cases were compensated during three years (2001-2003). Men accounted for many more cases than women. The most common age group was 41 -49. The majority of work-related psychiatric injuries were 'organic, including symptomatic, mental disorders', 'neurotic, stress-related and somatoform disorders' and 'mood [affective] disorders'. For accidental psychiatric injury cases construction and manufacturing were the most common industries. Manufacturing, business activities, construction and transport were common in regard to work-related psychiatric disorders. In this study there was a high frequency of craft and related trades workers, elementary occupations and plant and machine operators and assemblers in accidental psychiatric injury cases. Work-related psychiatric disorders were frequent for elementary occupations, plant and machine operators and assemblers, craft and related trades workers, service workers, legislators, senior officials and managers. Conclusion : This investigation provided more information about the psychiatric injuries of Korean workers. These findings should help formulate intervention and prevention strategies of work-related psychiatric disorders.

결핵균 단세포군항체에 의한 항산균항원의 면역화학적 분석에 관한 연구

최대경,백태현,박정규,김화중 충남대학교부설 생명공학연구소 1991 생물공학연구지 Vol.1 No.-

β-antigen is one of the major protein of Mycobacterium tuberculosis. We purified reference β-antigen from the unheated culture filtrate of Mycobacterium tuberculosis by serial ammonium sulfate precipitation, gel filtration on Sephacryl S-200 column and preparative polyacryamide gel electrophoresis. Nine monoclonal antibodies against β-antigen were produced by hybridoma technique. The nine monoclonal antibodies were divided into two groups according to their reaction patterns on Western blots. Four monoclonal antibodies(group Ⅰ) reacted with two major bands of 83 and 52 kDa, and two minor bands of 110 and 56 kDa molecules while the other five monoclonal antibodies(group Ⅱ) reacted with a major band of 83 kDa and a minor and of 110 kDa molecule. The interspecies reactivities of nine monoclonal antibodies on the sonicated antigens from 21 species of mycobacteria were also examined by dot blots. Two monoclonal antibodies, designated 4G5E10(group Ⅰ) and 5F3F2(group Ⅱ), showed a specificity restricted to Mycobacterium tuberculosis complex. β-antigien from the cell extract of Mycobacterium tuberculosis was purified by affinity chromatography with 5F3F2 monoclonal antibody and checked its molecular characterization. Affinity purified β-antigen showed two distinct bands of 83 and 52 kDa molecules on SDS-PAGE. These results indicating that β-antigen is a associated protein with molecular weights of 83 and 52 kDa, and contains at least two different specific epitopes for Mycobacterium tuberculosis complex on β- antigen molecules. Affinity purified and reference β- antigens were applied for its potential diagnostic utility for determination of LgG antibody in the cerebrospinal fluids and sera of tuberculosis patients by ELISA. The mean ELISA values of IgG antibody activities to affinity purified β-antigen at the CSF dilution of 1 : 5 were 0.866±0.607 in 12 patients with tuberculous meningitis and 0.058±0.040 in 24 controls(P<0.001). The mean ELISA values of IgG antibody activities to reference β-antigen at the serum dilution of 1 : 100 were 0.861±0.350 in 97 patients with minimal tuberculosis, 1.052±0.443 in 51 patients with moderately advanced, 1.381±0.396 in 49 patients with far advanced and 0.454±0.248 in 138 controls(P<0.01). An indirect sandwich ELISA using specific biotinylated 5F3F2 monoclonal antibody as tracer was designed to detect β-antigen in the culture filtrate of Mycobacterium tuberculosis and sputum samples from patients with pulmonary tuberculosis. The detection limit of indirect sandwich ELISA was 0.1㎍ culture filtrate/㎖. The mean ELISA values of β-antigen reactivities in sputum samples from 52 patients with pulmonary tuberculosis and 25 controls were 0.766±0.404 and 0.453±0.133(not significant).

확장 가능한 신경회로망 모듈 칩 설계

최명렬,조화현 漢陽大學校 工學技術硏究所 2000 工學技術論文集 Vol.9 No.1

본 논문에서는 간단한 비선형 시냅스 회로와 비선형 곱셈기를 이용하여 온 칩 학습기능을 포함한 모듈 칩을 설계하였다. 모듈 칩의 학습 회로는 MEBP(Modified Error Back-Propagation) 학습 규칙을 적용하여 구현하였으며, 모듈 칩이 출력 층과 은닉 층의 학습회로가 동일하므로 어떤 층에서도 사용 가능하도록 설계하였다. 제안한 모듈 칩은 HSPICE 회로 시뮬레이터를 이용하여 동작을 검증하였다. 제안한 모듈 칩은 확장 가능한 온 칩 학습 기능을 내장한 신경회로망 칩으로 대규모의 FNNs(Feedforwad Neural Networks) 구현에 매우 적합하리라 예상된다. A modular chip with on-chip learning has been implemented using nonlinear synapse circuits and nonlinear multiplier circuits. The MEBP(Modified Error Back-Propagation) learning rule is employed for learning circuitry. The module chip has been designed for use of any layer since the learning circuitry of the output layer is as same as that of the hidden layer. The operation of the proposed modular chip has been verified using HSPICE circuit simulator. The modular neural chip might be very suitable for the future implementation of the large-scale neural networks with on-chip learning.

건강인에서 결핵균 30-kDa항원이 말초혈액 임파구증식에 미치는 영향

최대경,고석신,김화중,조은경,백태현,신철식 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

T lymphocytes are thought to play a central role in cell mediated immune response. To Study the T lymphocyte proliferative response to 30-kDa antigen purified from Mycobacterium tuberculosis H37Rv, peripheral blood lymphocytes isolated from healthy subjects were stimulated with the 30kDa antigen, crude antigen or PHA. Healthy subjects were divided into three groups so that PPD(+), PPD(±) and PPD(-). The proliferations of lymphocytes were measured by the incroporation of ^3H-thyrnidine. The results were summarized as follows: 1. For the PPD(+) person, at concentration of < 1 ㎍/ml, the proliferative response to 30-kDa antigen resulted in a mild reduction but crude antigen showed relatively rapid reduction. For the PPD(-) person, decreasing the concentration of the both antigens showed rapid reduction of proliferation 2. The lymphocytes proliferations to 30-kDa antigen and crude antigen were significantly increased in PPD(+) group when compared to those in PPD(-) group, but PHA response was no significant difference. 3. The sensitivity and specificity of lymphocyte proliferation assay to 30-kDa antigen and crude antigen when compared with skin test results were 92.3%, 100% and 76.9%, 50%, respectively.

남제주 화력발전소의 증설과 저감대대책의 영향 분석

이화운,김유근,정우식,오은주,임헌호,노순아,반수진,최현정,김민선,김헌숙 부산대학교 환경문제연구소 2002 環境硏究報 Vol.20 No.-

In the view of the results investigated the effect of air pollutants that is emitted from a new generator facilities, the total estimated concentration which is the summation of a contributional concentration and observational concentration is much less than that of atmospheric environment criterion for the air pollutants. So we can predict that the operation of the new generator facilities with mitigation equipment don't seriously affect around environment. At the same time, we compared the contributional concentration of before mitigation equipment with that of after it to examine the decreasing amount due to mitigation equipment. The result showed that the concentration of SO2, NO2 and PM-10 is reduced to 25%, 30% and 26% of original value, respectively.

peat moss를 이용한 폐수중의 중금속 제거

이경화,김정섭,유현철,최성우,윤철종,우성훈,박승조 동아대학교 환경문제연구소 2001 硏究報告 Vol.24 No.1

Adsorption equilibrium of heavy metals ion on the peat moss was confirmed Frundlich isotherm Removal efficiency of heavy metals ion was increased from pH 2 to 10 and heavy metal removal efficiency was increased in the sequence of Cu(Ⅱ) > Pb(Ⅱ) > Cd(Ⅱ) > Mn(Ⅱ) on the PM(Peat Moss). The PM is likely to be more effective adsorption than the PAC to removal of metal ions in the solution, since PM's weakly acidic functional groups which is not founded on the PAC, in addition to its high surface area and porosity. But, the PM is not separated from the solution water by sedimentation process. So, a liquid and solid seperation between the PM and the solution water could be considered for the PM's field application. But peat moss was low cost adsorbent. Thus author propose to adopt PM as a adsorbent for heavy metal removal.

구간분할 바이너리 제어를 이용한 로봇핸드의 동특성에 관한 연구

정상화,차경래,김현욱,최석봉,김광호,박준호 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

In recent years, as the robot technology is developed the researches on the artificial muscle actuator that enable robot to move dextrously like biological organ become active. The widely used materials for artificial muscle are the shape memory alloy and the electro active polymer. These actuators have the higher energy density than the electromechanical actuator such as motor. However, there are some drawbacks for actuator. SMA has the hysterical dynamic characteristics. In this paper the segmented binary control for reducing the hysteresis of SMA is proposed and the simulation of anthropomorphic robotic hand is performed using ADAMS.