두경부 악성종양에 대한 MBD 유도화학요법의 임상적 고찰

김승찬,나한조 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

40 patients with head and neck cancer received the induction chemotherapy with methotrexate, bleomycin and cis-platinum (MBD) between January, 1988 and December, 1991. The results were as follows. 1) Among a total of 40 cases, 26 cases(65%) showed objective remission(complete remission 3cases, partial remission 23 cases). 2) Remission rates related to various primary tumor sites revealed that the oral cavity and larynx had relatively higher remission rate followed by the hypopharynx, the oropharynx and the nasopharynx. 3) There was no significant difference in the response rate according to patient characteristics such as primary tumor site, the degree of differentiation of tumor cells or stage of tumor. 4) This regimen (MBD) of induction chemotherapy produced only mild toxic reactions such as nausea and vomiting, mucositis and diarrhea, leukopenia and thrombocytopenia, ototoxicity, and nephrotoxicity. These reactions were easily controlled.

Multiple myeloma 환자에서 Bortezomib치료 후 발생한 마비성 장폐색증 1례

김준영,이원식,손창학,박성길,진한영,박석주,조영완,정은욱,강명주,박정하,주영돈 인제대학교 2006 仁濟醫學 Vol.27 No.-

Bortezomib is the first clinically available proteasome inhibitor that is clinically effective in the treatment of multiple myeloma. A proteasome inhibitor acts through multiple mechanisms to arrest tumor growth, tumor spread, and angiogenesis. The main adverse effects of bortezomib are gastrointestinal symptoms, cytopenia, fatigue, and peripheral neuropathy. To date, severe paralytic ileus has not been reported as a toxic effect of bortezomib treatment in multiple myeloma. Bortezomib is a novel agent that has only been used clinically for 30 months, so a need exists to further evaluate its toxicity. We report a case of grade Ⅲ (NCI CTCAE v3.0) or grade Ⅳ(SWOG toxicity criteria) paralytic ileus in a 65-year-old man with relapsed multiple myeloma who underwent one cycle of single-agent bortezomib treatment scheduled in a 21-day cycle (1.3 mg/㎥ as a single i.v. bolus on days 1, 4, 8, and 11).

심리훈련 프로그램 적용이 무용학습에 미치는 영향

김조은,한유선 圓光大學校 附設 體力科學硏究所 2002 體力科學硏究 Vol.25 No.1

The purpose of this study is to provide the psychological training program for dance learning in consideration of the methods and curricula used for dancing practice and teaching, and also to investigate the effect of applied psychological training program on characteristic anxiety. Surveyed were 120 high school students living in Jeonju who majored in dancing. They were divided into physical exercise group and psychological+physical exercise group and measured and analyzed before and after exercising. For this study, Spielberger's test for state-characteristic anxiety(STAI) was used and data were collected to find the level of characteristic anxiety by group, major, sex, grade, and career. The data, then, underwent statistical analyses of frequency, factors and reliability, T-test, and 2-way ANOVA. From the findings, it is concluded as follows: First, there is statistically significant difference in the characteristic anxiety of dancing majors by group(p<.05). The group who performed psychological training registered higher effect before than after the test in anxiety(3.906, 3.071), satisfaction(2.634, 3.277), calmness(2.098, 2.872), sensibility(2.125, 2.959), tension(3.722, 3.100), while there is no difference in the group without psychological training. Second, there is statistically significant difference in sensibility and tension depending on major of the dancing students(p<.05). Third, there is no statistically significant difference by career of dancing majors(p>.05), while variance analysis shows some interaction between calmness and sensibility. Especially big difference is found in calmness(1.788, 2.792) and sensibility(1.818, 2.854) of the majors with longer than 7 years experience.

초고압 전력기기의 온도상승 예측

김중경,김한균,민경조,한성진 東亞大學校附設 情報技術硏究所 2005 情報技術硏究所論文誌 Vol.13 No.1

This paper presents a new magneto-thermal finite element analysis for predicting the temperature rise of the EHV GIS bus bar. The power losses of a bus bar calculated by the magnetic field analysis are used as the input data to predict the temperature rise for the thermal analysis. The heat-transfer coefficients on the boundaries are analytically calculated by applying the Nusselt number considering material constant and model geometry for the natural convection. The temperature distribution in a bus bar by coupled magneto-thermal finite element analysis shows good agreement with the experimental data.

간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

적조생물구제농도의 Sodium Hypochlorite (NaOCl)의 노출에 따른 조피볼락 및 바지락의 조직학적 영향

한조희,김영석,허민도,정해진,박관하 한국환경독성학회 2001 환경독성보건학회지 Vol.16 No.2

In a previous study by Kim et al. (2000), sodium hypochlorite (NaOCI) has been demonstrated to be effective against algae that cause red tides. To secure the environmental safety of the chemical in practical use, effect of NaOC1, at concentrations. required for algicidal activity, on the histology of rockfish and little neck clam was examined. When the animals were exposed to NaOCI at concentrations of 0.5 or 2 ppm for I hr, there was no exposure-associated histological change in either animal. As the experimental exposure condition was set in consideration of the use, our results provide safety information necessary for practical application to marine fields.

상악동에 발생한 거대한 Cholesterol 육아종 1례

김승찬,박형욱,김용기,나한조,도남용 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.1

The cholesterol granuloma is not a specific clinical or pathologic entity but merely a term used to describe a tissue response to cholesterol crystal. The cholesterol granuloma in paranasal sinuses is rare disease. Recently the authors had experienced a case of huge cholesterol granuloma, which involved the right maxillary sinus. The cholesterol granuloma was removed successfully by mean of enucleation through the Caldwell-Luc approach. So, we report a case with brief review of the literature.

韓日涉外事件의 私法的硏究

鄭照根,金容漢 新羅大學校 1980 論文集 Vol.8 No.-

In accordance with the rapid growth of Korean economy, Korea is getting more important position in the international society. Keeping pace with such improvement and modernity of Korean economic society, our legal culture has fully arranged with required conditions for constitutionalism and in some particular parts it has remarkably developed. Besides, rationality and validity in legislation and its application are being varified. But we could not overlook the fact that the Japanese cognition about Korean Law is so unexpectedly feeble that precedents the international cases between Korea and Japan which are treated by the every Japanese courts including Japanese supreme court based on their misunderstanding about Korean Law or ignorance are not seldom. At this point, this paper, through positive study of precedents about international cases between Korea and Japan, focuses to improve international cognition about Korean legal culture and to verify proper position in private law of Korean residents in Japan. And this hind of study can not only improve Korean legal culture internationally but also induce national pride to 660 thousands of Korean residents in Japan and further more influence them greatly to ensure their private rights in Japan society. Therefore, I collected precedents of status relations in this study, for example, competence of courts cases, nationality and adoption cases, marriage cases, rights and duties of the parents and guardianship cases among Korea-Japan relations, which has been treated by the every Japanse courts including supreme court, and analyzed and criticized them. This writing is composed of following; 1. Introduction 2. The right of Jurisdiction in the international cases 3. Nationality and adoption cases between Korea and Japan 4. International marriage cases between Korea and Japan 5. International rights and duties of the parents and guardianship cases between Korea and Japan 6. Conclusion

Comparative Analysis of Human Epidermal and Peripheral Blood γδ T Cell Cytokine Profiles

( Kwangmi Kim1 ),( Jiyeon Han ),( Tae Ryong Lee ),( Dong Wook Shin ),( Hak Chang ),( A Ri Cho ),( Soon Jin Choi ),( Seong Jin Jo ),( Ohsang Kwon ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.3

Background: Human epidermal γδ T cells are known to play crucial roles in the defense and homeostasis of the skin. However, their precise mechanism of action in skin inflammation remains less clear. Objective: In this study, we analyzed the cytokine expression profile of human epidermal γδ T cells and compared it to that of peripheral blood γδ T cells to investigate the specific activity of epidermal γδ T cells in modulating skin inflammation. Methods: We isolated γδ T cells from epidermal tissue or peripheral blood obtained from healthy volunteers. Isolated γδ T cells were stimulated using immobilized anti-CD3 antibody and interleukin-2 plus phytohaemagglutinin, and were then analyzed using a cytokine array kit. Results: Both epidermal and peripheral blood γδ T cells produced comparable levels of granulocyte-macrophage colony-stimulating factor, I-309, interferon-γ, macrophage migration inhibitory factor, macrophage inflammatory protein-1α, and chemokine (C-C) ligand 5. The epidermal γδ T cells produced significantly higher levels of interleukin-4, -8, -13, and macrophage inflammatory protein-1β than the peripheral blood γδ T cells did. Notably, the epidermal γδ T cells produced several hundred-fold higher levels of interleukin- 13 than interleukin-4. Conclusion: These results suggest that the epidermal γδ T cells have a stronger potential to participate in the Th2-type response than the peripheral blood γδ T cells do. Furthermore, epidermal γδ T cells might play an important role in the pathogenesis of Th2-dominant skin diseases because of their active production of interleukin-13. (Ann Dermatol 26(3) 308∼313, 2014)

ZnS:Cu,Cl형광체의 제조와 발광특성

박조용,한상도,김병권,정영호,S. P. Khatkar,Liang, Yu Jun 경북대학교 센서기술연구소 2002 센서技術學術大會論文集 Vol.13 No.1