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      • KCI등재

        Algin 과 Chitosan 으로부터 제조한 생분해성 Film 의 생체적합성

        이홍열,황성규,김판기,김용렬,배지선,이한섭,류정욱 한국식품위생안전성학회 1999 한국식품위생안전성학회지 Vol.14 No.1

        Biodegradable films were prepared by solution blending method in the weight ratio of Chitosan and Algin for the purpose of useful bioimplants. The possibility of bioimplants, which prepared from natural polymers as a akin substitute and food wrapping materials were evaluated by measuring the biodegradability. these biodegradable films were inserted in the back of rats and their biodegradability was investigated by hematological change as a function of time. Rats study showed that low-Chitosan induced increments of monocyte and basophil after 48 hours of implantation. And medium-Chitosan showed increase of lymphocyte and decreased neutrophil counts after 48hours of implantation. Low, medium Chitosan showed high hemoglobin contents, medium and high Chitosan showed high hematocrit value after 48 hours of implantation. As a result, medium, high-Chitosan induced potential incompatibility in the tissue after 48 hours, but there was little effects to the akin inflammation. The values of biodegradable films, which prepared from natural polymers measured in this study were some satisfiable results at short period with those of ideal akin bioimplants and artificial skin.

      • The characteristic of decision making withdrawal or withholding in patients who were expired according to The Hospice, palliative Care, and Life-sustaining treatment decision-making Act

        이홍열,김성현,양지영,김미영,이영민,이현경 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-

        Introduction: The Hospice, palliative Care, and Life-sustaining treatment decision-making Act was come into force in February 2018 in Korea. We reviewed the characteristics of patients who withdraw or withhold life-sustaining treatment in tertiary care hospital. Methods: Retrospective data were analyzed for the period from February to August 2018. We review patients who had expired according to The Hospice, palliative Care, and Life-sustaining treatment decision-making Act. Included were 33 patients who had made a decision to withdraw or withhold life-sustaining treatment. 9 patients were discharged after filling in the Physician Orders for Life-sustaining Treatment (POLST). Another 24 patients were expired as withdrawal or withholding life-sustaining treatment. Result: 14 of 24 patients had the end stage of disease. Last of them were critically ill patient who were finally judged ‘the last days of life’ for dying patient care. Patient who had preexisting POST were 6. One Patient had advanced directive. Life-sustaining decision making for another 17 patients were made by their family members. 9 decisions by presumption of patients’ living will and 8 decisions by agreement of all family members. Only 4 patients were expired according to withhold the life-sustaining treatment. Others were expired according to withdrawal life-sustaining treatment. Conclusion: Patients who were expired according to The Hospice, palliative Care, and Life-sustaining treatment decision-making Act were expired by withdrawal life-sustaining treatment. The decision were made by family members.

      • 집성 목재에 관하여 -강도를 중심으로 한 소고- - 강도를 중심으로 한 소고 ( Glued Laminated Lumber )

        이홍열 대한건축학회 1971 建築 Vol.15 No.1

        목재는 성장과정에서 발생하는 일차결점으로 인해 잠시구축되였으나 제1차대전의 발발로 말미암아 각국의 철재 부족이 절정에 달하자 다시 목구조에 관한 연구에 심혈을 경주한 결과 신흥목구조를 출현시키는데 성공했다. 대재를 구득할 수 없는 지역적 사정은 소재를 조합하는 접합법과(glued laminated lumber)화 위해 많은 노력을 한 결과 눈부신 발전을 했다. 목재자원이 풍부한 우리나라는 건축기술면에 있어서 고도의 발전을 하였음을 오늘날 국보급 건축물로서 입증하고 있다. 그러나 광복과 사변의 무질서와 혼란기를 전후하여 산림보호육성은 외면한채 무모한 채벌을 하였고, 전국 생산량의 태반을 차지하는 지역은 미수복으로 끝났으며 또 건축재 이외의 이용도가 급증하여 수급에 큰 차질이 생겨 근래 수요의 대부분을 외국 생산재에 의존하고 있다. 요즘과 같이 도시건축물의 밀도가 높아짐에 따라 구조체가 불연재이기를 원하는 것은 당연하나 현금 철재 등 자원이 풍부한 외국에서는 목조건물이 과반수를 차지하고 있음은 목재가 지니고 있는 우위성에 원인이 있는 것으로 생각 한다.

      • KCI등재

        Bethe's Small Hole Coupling을 이용한 유전체의 밀리미터파대 유전특성 평가방법에 관한연구

        이홍열,전동석,한진우,이상석 한국전기전자재료학회 2002 전기전자재료학회논문지 Vol.15 No.12

        The circular cavity resonator which can measure the dielectric properties of dielectrics in the Ka-band(26.5GHz∼400Hz) frequency range was designed and fabricated. A structure of the resonator is divided into two equal parts of the length and the dielectric plate sample is placed between two halves. Exciting and detecting of the resonator is Performed by WR28 rectangular waveguides using Bethe's small hole coupling. The GaAs plate sample, whose performance is known to be 13 in millimeter wave range, was used for the verification of the performance of the fabricated circular cavity resonator In the measurement of GaAs single crystal using that resonator, the resonant frequency of the dominant TE$\sub$011/ mode, the permittivity and Q${\times}$f$\sub$0/ were measured as 26.69GHz, 12.9 and 124,000GHz, respectively.

      • 建築物의 內部 色彩에 關하여 (I 實態調査) : 釜山市內 住宅을 中心으로 Centering on living houses in Pusan

        李洪烈 釜山工業大學校 1971 論文集 Vol.12 No.-

        조사 기관 중 일기나 실조성 등으로 얼룩이 없는 조사를 했다고 할 수 없으나 현황 파악에는 충분한 것으로 믿으며 반성과 아울러 앞으로의 색채 계획에 있어 좋은 참고 자료가 될 것으로 생각한다. 앞날의 색채 계획은 결점부분의 시정은 물론 우리 나라 국민의 색감정에 알맞는 채색을 위해서는 많은 연구와 노력이 있어야 겠다.

      • Risk of cancer incidence in patients with idiopathic pulmonary fibrosis : A National Health Insurance Service data analysis

        이홍열,이진우,이창훈,최선미 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-

        Introduction: Limited population-based data are available on cancer risk among patients with idiopathic pulmonary fibrosis (IPF). The aim of our study was to compare the incidence risk of various cancers among patients with IPF and those without IPF based on the National Health Insurance Service (NHIS) database in Korea. Method: Patients with IPF who did not have a previous diagnosis of cancer were selected from the NHIS database between 2009 and 2015. An age-, sex-, and year of diagnosis-matched control population of individuals without IPF was randomly selected at a control-to-case ratio of 3:1. Both cohorts were followed up to observe cancer occurrence based on ICD-10 diagnosis code until December 2016. Results: A total of 24,177 patients with IPF were included. The incidence rate of newly diagnosed cancer was 33.5 cases per 1,000 person-years in patients with IPF and 13.6 cases per 1,000 person-years in the control cohort. After adjusting for age, sex, and diabetes mellitus, patients with IPF showed a significantly higher risk of overall cancer (adjusted hazard ratio [aHR], 2.51; 95% confidence interval [CI], 2.33-2.70). Lung cancer showed the highest aHR (aHR, 7.57; 95% CI, 6.58-8.71), followed by multiple myeloma, cervical cancer, lymphoma, cancer of central nervous system, breast cancer, liver cancer, colorectal cancer, pancreatic cancer, prostate cancer, thyroid cancer, and gastric cancer. Conclusion: Patients with IPF had a higher risk of overall cancer compared to controls without IPF. Greater attention should be paid to cancer development in patients with IPF.

      • Prevalence and prognostic impact of various malignant disease in patients with idiopathic pulmonary fibrosis

        이홍열,조재영,이진우,박영식,이창훈,이상민,임재준,유철규,김영환,한성구,최선미 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-

        Introduction: The aim of our analysis was to determine the prevalence of various malignant diseases in patients with idiopathic pulmonary fibrosis (IPF) and its prognostic impact. Method: We retrospectively reviewed all medical records and chest CT images of patients diagnosed with IPF between January 2001 and December 2015. They were divided into three groups: IPF without cancer (n=445), IPF with lung cancer (n=68), and IPF with cancer other than lung cancer (n=66). Results: A total of 579 IPF patients were included, of whom 133 (23%) had cancer. The three most common cancers were lung (11.6%), gastric (2.2%), and colorectal cancer (1.9%). Survival was significantly worse among IPF patients with lung cancer than among those without cancer (HR=1.927, 95% CI, 1.398-2.658) or those with any other cancer (HR=1.597, 95% CI, 1.047-2.436). Survival rates did not differ between IPF patients without cancer and those with any other cancer. Number of visits to emergency room (ER) and admissions to intensive care unit (ICU) per year were significantly higher among IPF patients with cancer than in those without cancer. However, these values were similar between IPF patients with lung cancer and those with any other cancer. The annual rate of decline in %predicted FVC and DLCO did not differ among groups. Conclusion: Lung cancer is the most common cancer among IPF patients and has a worse impact on survival than other cancers. Annual ER visits and ICU admissions are significantly more frequent among IPF patients with any type of cancer than among those without cancer.

      • Effect of a rapid response team on code rates and in-hospital mortality in medical wards

        이홍열,이진우,이상민,김설희,양은진,주영신,이현주,이한나,류호걸,오승영,하은진,고상배,조재영 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-

        Objective: To determine the effect of a rapid response team (RRT) implementation on code rates and in-hospital mortality in medical wards. Method: This retrospective study included adult patients admitted to medical wards at Seoul National University Hospital between 12 July 2016 and 12 March 2018. A total of 4,718 patient admissions in 10 months before RRT implementation and 4,168 patient admissions in 10 months following RRT implementation were evaluated. Our RRT only works during daytime hours (7 AM to 7 PM) on weekdays. We compared code rates and in-hospital mortality between pre- and post-RRT implementation. Results: There were 76.5 RRT activations per 1,000 admissions and the most common reasons for RRT activation were tachypnea or hypopnea (38%), hypoxia (29%), and tachycardia or bradycardia (19%). After RRT implementation, code rates from medical wards during daytime significantly decreased from 3.18 to 0.96 per 1,000 admissions (adjusted odds ratio [aOR], 0.31; 95% confidence interval [CI], 0.09-0.86; p=0.038). However, code rates from medical wards during off time did not differ between the pre-RRT and post-RRT periods (2.12 vs 2.88 per 1000 admissions; aOR, 1.40; 95% CI, 0.60-3.31; p=0.436). In-hospital mortality significantly decreased from 5.26 to 4.25 per 100 admissions after RRT implementation (aOR, 0.82; 95% CI 0.67-1.00; p=0.048). Conclusion: Implementation of RRT was associated with a significant reduction in both code rates during daytime and in-hospital mortality in medical wards.

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