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이규섭,하명완,나상 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.6
저자는 최근 본 병원 산부인과에서 태아경부 수활액낭종 1례를 경험하였기에 이에 대한 간단한 문헌적 고찰과 함께 보고하는 바이다. It had been thought that cystic hygroma colli was diagnostic of Turners syndrome in utero and that it was the precursor of the neck webbing or redundant skin in the nuchal region found after birth. In later studies, however, cystic hygroma was found in fetuses with other chromosome abnormalities and with normal karyotypes. The term hygroma means moist tumor. Cystic hygromas are anomalies of the lymphatic system characterized by single or multiple cysts within the soft tissues, usually involving the neck. Recently, we have experienced a case of fetal cystic hygroma colli at 22 weeks of gestation observed in 25-year-old nulliparous woman, and report that with a brief review of related literatures.
Cu(001) 표면에 성장시킨 Ni 초박막의 구조 연구
閔恒基,李圭燮 弘益大學校 科學技術硏究所 1995 科學技術硏究論文集 Vol.6 No.-
The growth of Ni deposited on Cu(001) surface at room temperature was studied by LEED(Low Energy Electron Diffraction) I/V analyses. For the Ni thin films of thickness from 1 ML(mono layer), the subsurface Ni layer below 1 ML Cu surface layer is found to be the optimum structure. This result is also consistent with the growth mode predicted by the first principles total energy calculation.
자궁내막증 환자의 복강액으로 처리한 단핵구가 T-세포 반응에 미치는 영향에 관한 연구
이규섭 부산대학교 병원 암연구소 2006 부산대병원학술지 Vol.- No.20
Purpose: This study examined whether or not the PF from endometriosis patients (EPF)-treated monocytes affect the T cell response. Subject and Methods: Peritoneal fluid was obtained from endometriosis patient(n=20) and healthy control group(n=10) respectively. Peripheral blood monocytes were obtained from healthy donors by density-gradient centrifgation and THP-l cells derived from a monocyte/macrophage cell line. We examined the effects of heat-treatment and IL-10 neutralizing antibody on the down-regulation of MHC class IT expression level by EPF. The monocytes pre-treated with 10% of EPF mixture were mixed with T-cells, cultured with or without Staphylococcus enterotoxin B(SEB), and then pulsed with 1μCi of [^(5)H] thymidine. The radioactivity incorporated was determined. EPF-treated or CPF-treated monocytes were mixed with T-cells and cultured. The expression of MHC class Ⅱ was evaluated by confocal microscopic analysis, and the levels of IL-10, TGF-β and VEGF were measured by standard enzyme-linked immunosorbent assay kits(R and D system). Results: Heat-pretreatment of EPF and neutralizing IL-10 antibody abrogated MHC class Ⅱ down-regulation on monocytes, which had been induced by EPF. However, in a functional assay, monocytes treated with EPF failed to stimulate T cell in mixed leucocyte reaction, although T cell proliferation was increased with EPF-treated monocytes and SEB. Conclusion: These results suggest that the cell stimulatory ability of monocytes dose not coincide with MHC class Ⅱ expression level.