슬통 진단용 설문지개발 및 진단 일치도 평가연구

황지후,김유종,김은정,이참결,이은용,이승덕,김갑성 대한침구의학회 2012 대한침구의학회지 Vol.29 No.5

Objectives : This study is perfomed for preparation of oriental medicine clinical guidelines for drawing up the standards of oriental medicine demonstration and diagnosis classification about the knee pain. Methods : Statistical analysis about Crane’s-knee wind(鶴膝風), arthralgia syndrome(痺症), knee injury(膝傷), gout arthritis(痛風), Youk jeol poung(歷節風) classified experts’ opinions about knee pain patients by Delphi method is conducted by using oriental medicine diagnosis questionnaire. The result was classified by using linear discriminant analysis(LDA), diagonal linear discriminant analysis(DLDA), diagonal quadratic discriminant analysis(DQDA), K-nearest neighbor classification(KNN), classification and regression trees(CART), support vector machines(SVM). Results : The results are summarized as follows. 1. The result analyzed by using LDA has a hit rate of 81.65% in comparison with the original diagnosis. 2. The result analyzed by using DLDA has a hit rate of 63.3% in comparison with the original diagnosis. 3. The result analyzed by using DQDA has a hit rate of 65.14% in comparison with the original diagnosis. 4. The result analyzed by using KNN has a hit rate of 74.31% in comparison with the original diagnosis. 5. The result analyzed by using CART has a hit rate of 75.23% in comparison with the original diagnosis when the test of selected 13 significant questions based on analysis of variance was performed. 6. The result analyzed by using SVM has a hit rate of 87.16% in comparison with the original diagnosis. Conclusions : Statistical analysis using oriental medicine diagnosis questionnaire on knee pain generally turned out to have a significant result.

스마트 콘트랙트와 IPFS를 활용한 재능거래 플랫폼 개발

황지후(JiHu Hwang),이준혁(JunHyeok Lee),이중찬(JoongChan Lee),서창진(Cheng-Jin Seo) 대한전기학회 2022 대한전기학회 워크샵 Vol.2022 No.7

해외 선진국의 소방안전 정보시스템 분석을 통한 시사점 도출

황지후(Hwang Ji hoo),권혁진(Kwon hyuck jin),김한수(Hansoo Kim) 한국통신학회 2019 한국통신학회 학술대회논문집 Vol.2019 No.6

중온박리 방지제 첨가에 따른 아스팔트 혼합물 공용성능 평가에 관한 연구

설지후,황성도,가현길,문성호 한국도로학회 2022 한국도로학회논문집 Vol.24 No.2

PURPOSES : This study compared the performance evaluation of a hot mix asphalt (HMA) and asphalt mixture of a warm-antistrip agent. METHODS : A mix design applying Korean standards was conducted to evaluate the performance evaluation. Thereafter, the quality standard evaluation of the asphalt mixture produced was conducted, and if all quality standards were satisfied, a performance evaluation was conducted. Types of performance evaluation included the Hamburg wheel tracking test and dynamic modulus test. RESULTS : As a result of the Hamburg wheel tracking test, the asphalt mixture with a warm-antistrip agent obtained a lower sedimentation value at 10000 times and 20000 times. This result is considered to have higher plastic deformation resistance of the asphalt mixture with a Warm-antistrip agent than HMA. The U.S. Department of Transportation stipulates that plastic deformation resistance is excellent if the asphalt mixture does not exceed 20,000 times the precipitate of 20 mm. Therefore, we confirmed that the plastic deformation resistance of the asphalt mixture with a warm-antistrip agent was excellent. Additionally, the master curve was analyzed by synthesizing the results of the dynamic modulus test. When analyzing the low load cycle at the bottom left of the master curve, the dynamic modulus value of the master curve was higher in the asphalt mixture with a warm-antistrip agent than in the HMA. In addition, when analyzing the high load cycle part, the dynamic modulus of the HMA was measured to be higher than that of the asphalt mixture with a warm-antistrip agent. Accordingly, the resistance to fatigue cracking of the asphalt mixture with a warm-antistrip agent was considered superior to that of the HMA. CONCLUSIONS : As a result, we confirmed that the asphalt mixture with a warm-antistrip agent that satisfies the Korean quality standards had better plastic deformation and fatigue resistance for all performance evaluation tests conducted in this study than the HMA. However, since the Hamburg wheel tracking test did not significantly differ in the amount of sedimentation in the performance evaluation tests and the mixture using one additive was compared with HMA, studies on the effects of various additives containing warm-antistrip agents are required.

경혈탐측기를 이용한 말초성 안면신경마비환자의 족부반사구 변화에 대한 임상적 고찰

왕개하,이은솔,황지후,김유종,김경호,김승현,윤인애,조현석 대한침구의학회 2012 대한침구의학회지 Vol.29 No.1

Objectives : We investigate the characteristics of foot reflex zone acupoint of facial paralysis patients. Methods : In order to make a comparison between facial nerve paralysis patient group and non-facial paralysis group, we measured foot reflex zone acupoint detection in both group of 18 patients who were diagnosticated to facial nerve paralysis and 18 persons who were not. Results :1. In comparing the means of the foot reflex zone, the measurements of facial nerve paralysis group is different significantly from non-facial paralysis group(p<0.05). 2. The measurement of detection of foot reflex zone acupoints, such as hypophysis(垂體), nose(鼻), cerebrum(大腦), neck(頸項), Trapezius muscle(僧帽筋), eye(眼) and ear(耳) of the facial nerve paralysis group is different significantly in comparison with non-facial paralysis group(p<0.05). But the measurement of detection of foot reflex zone acupoints, such as trigeminal nerve(三叉神經), cerebellum(小腦), kidney(腎), ureter(輸尿管) and urinary bladder(膀胱) of the facial nerve paralysis group is not defferent significantly in comparison with non-facial paralysis group(p>0.05). Conclusions : The results suggest that foot reflex zone can be used in the diagnosis and treatment of facial nerve paralysis.

요통환자 대상 오적산 엑스산 투여 임상시험 이상반응 연구

윤은혜,장민기,황지후,이승훈,정원제,이재동,이승덕,김경호,김갑성,김은정,Yoon, Eun-Hye,Jang, Min-Gee,Hwang, Ji-Hoo,Lee, Seung-Hoon,Jeong, Won-Je,Lee, Jae-Dong,Lee, Seung-Deok,Kim, Kyung-Ho,Kim, Kap-Sung,Kim, Eun-Jung 대한침구의학회 2010 대한침구의학회지 Vol.27 No.4

Objectives : This study was performed to report adverse events in Ojeok-san extract powders RCT. Methods : 180 patients with LBP were randomized into groups for a double blind, placebo-controlled clinical study. They received Ojeok-san simple Extract, Ojeok-san complex Extract or placebo in powders, orally dissolved 3times a day for 4weeks. During 4weeks, we researched the symptoms and duration of adverse events and Digest ability, Milk hypersensitivity, Starch hypersensitivity, Caramel hypersensitivity, West-med hypersensitivity, Herb-med hypersensitivity in patients who had adverse events. Results : 52patients(28.9%) had adverse events and of them 44patients(28.9%) had lost adverse events naturally. But 5patients(2.8%) were withdrawn from the research because of the adverse events. Most of the symptoms of adverse event was Gastrointestinal symptom(88.3%) and adverse events frequency was not different from Ojeok-san simple Extract, Ojeok-san complex Extract and placebo. Conclusions : Ojeok-san extract powders had adverse events no different from the placebo, which shows that it is a safe drug.

홍화자유약침이 CIA 모델 생쥐의 윤활관절막 손상 억제에 미치는 영향

백성욱,김은정,황지후,윤종화,이승덕,김갑성 대한침구의학회 2012 대한침구의학회지 Vol.29 No.1

Objectives : The purpose of this study is to observe the inhibitory effects of Chrthami semen oil pharmacopuncture(CSOP) on CIA (collagen-induced arthritis) mice. Materials and Methods : Two types of experiments were conducted: in vitro assay, inhibition of MIF mRNA and TNF-α mRNA expressions in synovial membranes was observed, and in vivo assay, 1 ㎕/㎏ CSOP was injected every day to the left Weizhong (BL40) from day 3 to 21 after induction of CIA, and changes in paw edema, apical surface morphology, neovascularization in synovial membranes, fibrosis, pro-inflammatory cytokines production, Th-1 differentiation, and anti-inflammatory effect were investigated. Results : 1. In synoviocytes of the CIA mice treated with CSOP, MIF mRNA and TNF-α mRNA expressions were down-regulated in a dose-dependent manner. 2. Paw edema of the CIA mice treated with CSOP was diminished. 3. Tissue injury in the synovial membranes, capillary distribution and fibrosis were reduced in CSOP-treated mice. 4. MIF, TNF-α, IL-6, MMP-9 expressions were repressed in CSOP-treated mice during the experiment to observe the inhibitory effect on cytokines production in early stage RA. 5. IL-12 and CD28 were reduced in CSOP-treated mice during the observation of inhibitory effect on Th1 differentiation. 6. PPAR-γ was increased during the experiment to observe the anti-inflammatory effect of CSOP. Conclusions : The results may suggest that administration treatment using Chrthami semen oil pharmacopuncture decreases the inflammatory response on an Animal Model with CIA.

요통환자 대상 오적산 엑스산 투여 임상시험 이상반응 연구

윤은혜,장민기,황지후,이승훈,정원제,이재동,이승덕,김경호,김은정,김갑성 대한침구의학회 2010 대한침구의학회지 Vol.32 No.4

Objectives : This study was performed to report adverse events in Ojeok-san extract powders RCT. Methods : 180 patients with LBP were randomized into groups for a double blind, placebo-controlled clinical study. They received Ojeok-san simple Extract, Ojeok-san complex Extract or placebo in powders, orally dissolved 3times a day for 4weeks. During 4weeks, we researched the symptoms and duration of adverse events and Digest ability, Milk hypersensitivity, Starch hypersensitivity, Caramel hypersensitivity, West-med hypersensitivity, Herb-med hypersensitivity in patients who had adverse events. Results : 52patients(28.9%) had adverse events and of them 44patients(28.9%) had lost adverse events naturally. But 5patients(2.8%) were withdrawn from the research because of the adverse events. Most of the symptoms of adverse event was Gastrointestinal symptom(88.3%) and adverse events frequency was not different from Ojeok-san simple Extract, Ojeok-san complex Extract and placebo. Conclusions : Ojeok-san extract powders had adverse events no different from the placebo, which shows that it is a safe drug.

격물구와 상용 간접구의 온열자극 비교 연구

장민기,김은정,정찬영,윤은혜,황지후,김갑성,최인화,이승덕 대한침구의학회 2010 대한침구의학회지 Vol.27 No.3

Backgrounds : Recently, commercial indirect moxibustion has been widely used as a substitute for traditional indirect moxibustion by clinicians due to its convenience in using. But, there has been lack of studies about the similarity of thermal stimulation between commercial indirect moxibustion and traditional indirect moxibustion. Objectives : To demonstrate commercial indirect moxibustion can substitute for traditional indirect moxibustion by comparing thermal stimulation between the two. Methods : We measured bottom temperature of commercial indirect moxibustion and traditional indirect moxibustion with various thicknesses of ginger and garlic. A clinical trial was performed on 18 healthy subjects to evaluate thermal stimualtion. The subjects were randomly assigned into two groups, traditional indirect moxibustion with ginger and garlic. The skin temperature and heating time were measured. They received moxibustion therapy with commercial indirect moxibustion and traditional indirect moxibustion according to their groups. Acupoint Chogcoe(LU6), Zusanli(ST36) and Tianshu(ST25) were used in each group for 3 times. Results : There was no difference in bottom temperature among commercial indirect moxibustion, traditional indirect moxibustion with 2㎜ ginger and 3㎜ garlic. No major difference was detected in the subjects’ baseline data. There was no difference in skin temperature and heating time among these 3 type of moxibustions. Also, No major difference was detected in VAS score of thermal stimulation and frequency of burns among these 3 type of moxibustions. But, most subjects regarded their sensation weren’t identical because of its own distinct characteristics. Conclusions : Commercial indirect moxibustion, traditional indirect moxibustion with 2㎜ ginger and 3㎜ garlic have same thermal stimulation. Thus, commercial indirect moxibustion can substitute for traditional indirect moxibustion.

급성 외상성 반월연골 파열에 대한 한의학적 치료 증례보고 4례

허우영,현민경,모민주,김한옥,박재현,황지후 대한침구의학회 2015 대한침구의학회지 Vol.32 No.2

Objectives : The purpose of this study is to report the effect of Korean medical treatment on 4 patients with acute traumatic meniscal tear, presenting severe knee pain and limitation of range of motion of the knee joint. Methods : 4 patients with acute traumatic meniscal tear had been treated with acupuncture, herbal treatment, moxibustion, and wet-cupping therapy. From administration to discharge, we recorded subjective pain by using a visual analogue scale and by measuring the range of motion of the knee joint once per week. Results : The visual analogue scale of knee pain of all 4 cases reduced to 0 after treatment. The range of motion of the knee joint also increased considerably after treatment. Conclusions : In this study, Korean medical treatment may have been effective in reducing knee pain and increasing the range of motion of the knee joint.