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      • KCI등재

        췌장 선암의 절제 가능성 평가

        황신혜,박미숙 대한영상의학회 2021 대한영상의학회지 Vol.82 No.2

        Imaging studies play an important role in the detection, diagnosis, assessment of resectability, staging, and determination of patient-tailored treatment options for pancreatic adenocarcinoma. Recently, for patients diagnosed with borderline resectable or locally advanced pancreatic cancers, it is recommended to consider curative-intent surgery following neoadjuvant or palliative therapy, if possible. This review covers how to interpret imaging tests and what to consider when assessing resectability, diagnosing distant metastasis, and re-assessing the resectability of pancreatic cancer after neoadjuvant or palliative therapy. 췌장 선암의 발견, 진단, 절제 가능성 평가, 병기 설정 및 치료 방침 결정에 영상 검사는 중요한 역할을 담당하고 있다. 최근에는 진단 당시 경계절제성 혹은 국소 진행성 췌장암을 진단받은 경우 선행 보조 치료 또는 완화 치료 후 가능하면 근치적 절제술을 고려할 것이 권고된다. 이 종설에서는 췌장 선암의 절제 가능성 평가, 원격 전이의 진단 및 선행 보조 치료 또는완화 치료 후 절제 가능성을 재평가할 때 영상 검사의 해석, 판독 기준 및 고려할 사항에 대하여 설명하고자 한다.

      • KCI등재

        Radiologic features of hepatocellular carcinoma related to prognosis

        황신혜,이형진 대한간암학회 2023 대한간암학회지 Vol.23 No.1

        The cross-sectional imaging findings play a crucial role in the diagnosis of hepatocellular carcinoma (HCC). Recent studies have shown that imaging findings of HCC are not only relevant for the diagnosis of HCC, but also for identifying genetic and pathologic characteristics and determining prognosis. Imaging findings such as rim arterial phase hyperenhancement, arterial phase peritumoral hyperenhancement, hepatobiliary phase peritumoral hypointensity, non-smooth tumor margin, low apparent diffusion coefficient, and the LR-M category of the Liver Imaging-Reporting and Data System have been reported to be associated with poor prognosis. In contrast, imaging findings such as enhancing capsule appearance, hepatobiliary phase hyperintensity, and fat in mass have been reported to be associated with a favorable prognosis. Most of these imaging findings were examined in retrospective, single-center studies that were not adequately validated. However, the imaging findings can be applied for deciding the treatment strategy for HCC, if their significance can be confirmed by a large multicenter study. In this literature, we would like to review imaging findings related to the prognosis of HCC as well as their associated clinicopathological characteristics

      • KCI등재

        Risk of Thyroid Cancer in Euthyroid Asymptomatic Patients with Thyroid Nodules with an Emphasis on Family History of Thyroid Cancer

        황신혜,김은경,문희정,윤정현,곽진영 대한영상의학회 2016 Korean Journal of Radiology Vol.17 No.2

        Objective: To determine the factors associated with thyroid cancer, focusing on first-degree family history and ultrasonography (US) features, in euthyroid asymptomatic patients with thyroid nodules. Materials and Methods: This retrospective study included 1310 thyroid nodules of 1254 euthyroid asymptomatic patients who underwent US-guided fine-needle aspiration biopsy between November 2012 and August 2013. Nodule size and clinical risk factors–such as patient age, gender, first-degree family history of thyroid cancer, multiplicity on US and serum thyroid stimulating hormone (TSH) levels–were considered together with US features to compare benign and malignant nodules. Multiple logistic regression analysis was performed to assess the risk of thyroid malignancy according to clinical and US characteristics. Results: Although all of the clinical factors and US findings were significantly different between patients with benign and malignant nodules, a solitary lesion on US (p = 0.041–0.043), US features and male gender (p < 0.001) were significant independent risk factors for thyroid malignancy in a multivariate analysis. Patient age, a first-degree family history of thyroid cancer and high normal serum TSH levels did not independently significantly increase the risk of thyroid cancer. However, multicollinearity existed between US assessment and patient age, first-degree family history of thyroid cancer and serum TSH values. Conclusion: Ultrasonography findings should be the primary criterion used to decide the management of euthyroid asymptomatic patients with thyroid nodules. The concept of first-degree family history as a risk factor for thyroid malignancy should be further studied in asymptomatic patients.

      • KCI등재

        황금(黃芩)의 에탄올추출물에 의한 화장품 방부효과

        황신혜(Shin Hye Hwang),박창호(Chang-Ho Park) 한국생물공학회 2009 KSBB Journal Vol.24 No.4

        Skin toner와 skin lotion의 두 가지 화장품 formulation에 기존의 파라벤류 방부제 대신 황금 (黃芩) 추출물 (1.0 wt%)을 첨가하고 Staphylococcus aureus (ATCC 25923), Pseudomonas aeruginosa (ATCC 9027) 및 Candida albicans (ATCC 10231) 균주를 접종하였을 때 이 균주들은 7일 이내에 99.9% 이상의 사멸율을 보여 황금추출물이 CTFA기준을 만족하는 항균력이 있음을 확인하였다. 다만 skin lotion에 접종된 Candida albicans의 경우 사멸율은 CTFA기준에 약간 미달하는 99.8%이었다. 또한 황금추출물의 농도가 1.0 wt% 이하일 때 균주의 생존율은 그람 양성균인 S. aureus가 가장 높고 그람 음성균인 P. aeruginosa가 가장 낮았다. 전계방출형 주사전자현미경 (FE-SEM)을 이용한 세포형태변화 관찰 결과 황금추출물이 P. aeruginosa에 대하여 더 큰 방부력을 갖는 것은 이 균주의 세포막이 황금추출물에 의해 더 심하게 손상되기 때문으로 사료된다. 고농도의 황금추출물이 더 높은 항산화 효과를 나타냈으며 1,000 ppm에서 80%정도의 SOD- 유사활성을 나타내었다. Ethanol extract (1.0 wt%) of Scutellaria baicalensis GEORGE practically satisfied CTFA (The cosmetics, Toiletry, and Fragrance Association) standard in its antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans which were inoculated in skin toner and skin lotion. At concentrations of the extract less than 1.0 wt% the survival rate was the best for S. aureus and the worst for P. aeruginosa. The antimicrobial effect seems to be due to the damage to the bacterial cell wall as evidenced by the images of a Field Emission-Scanning Electron Microscope. The extract also showed a high anti-oxidant effect, and superoxide dismutase (SOD)-like activity reached 80% at 1,000 ppm. These findings suggest that the extract of Scutellaria baicalensis GEORGE is applicable to cosmetics as a natural preservative and an anti-oxidant.

      • KCI등재

        생태학적 접근으로 본 다문화가정 기혼여성의 주거경험에 관한 연구

        황신혜 ( Shin Hye Hwang ),홍형옥 ( Hyung Ock Hong ) 대한가정학회 2016 Human Ecology Research(HER) Vol.54 No.2

        This study examined the nature of multi-cultural families` housing problems living in South Korea. A qualitative research was conducted through in-depth interviews with immigrant women from three Southeast Asian countries. The subjects of this study were 15 married immigrants from the Philippine, Cambodia, and Vietnam living in Seoul. The major findings were as follows: firstly, reciprocity for the in-between person and environment: the preferred to blend into Korean society instead of making a community based on national origin. Secondly, intention to housing: all participants were passive about moving and the Vietnamese and Cambodians placed more importance on the family community than the Filipinas. Thirdly, meaning of housing and interaction: for the most important area in the house, the Vietnamese and Cambodians stated that rooms were for a couple and treated family space more importantly than Filipinas who pursuit personal comfort. Fourthly, housing adaptation process: adapting to climate difference between home countries and Korea was the biggest difficulty. Fifthly, residential satisfaction/dissatisfaction: mostly satisfied with housing facilities; however, they were dissatisfied with the number of rooms and house size due to a necessity for personal space. In conclusion, ideas implied from native country of married immigrants in multicultural families did not change significantly in preference of the current environment. The needs for an ethnic community was not great, because they seemed able to assimilate positively by living with a Korean husband and relatives. Gradual assimilation through a cultural acculturation process can be considered desirable.

      • KCI등재

        지하철 무인 승차권 발매기 UI 사용 경험 연구

        황신혜(Shin-Hye Hwang),최종훈(Jong-Hoon Choe) 한국콘텐츠학회 2015 한국콘텐츠학회논문지 Vol.15 No.6

        서울시 지하철 무인 승차권 발매기는 이원화된 종이 승차권과 교통카드 시스템의 통합 관리 및 역무 인력의 효율적 운영을 위해 도입된 키오스크 형태의 1회용 교통카드 발급기이다. 그러나 서울시에 설치된 지하철 무인 승차권 발매기는 여전히 이용과정에서 혼란 및 불편함을 발생시키고 있으며, 이에 따라 사용성 개선에 대한 방향성 고찰이 필요한 실정이다. 본 연구를 위해 먼저 지하철 무인승차권 발매기에 관한 도입배경 및 운영에 대한 문헌 조사를 진행하였다. 또한 UI 구조를 분석하여 문제점을 예상한 후, 유동인구가 많은 9호선 신논현역 무인승차권 발매기를 대상으로 사용자들의 이용행태를 관찰하였다. 분석 결과, 구매절차는 구간금액이나 목적지역을 선택하는 과정으로 이용이 가능하나 선택한 구간 금액이 원하는 목적지와 일치하는지 판단이 어려웠으며, 목적지역 탐색 과정은 화면의 복잡도로 인해 시간이 지체되는 문제점을 발견할 수 있었다. 이러한 조사결과를 기반으로 각 시스템 화면별 개선사항을 도출하여, 향후 체계적이고 효율적인 시스템 구축을 위한 방향성을 제시하고자 하였다. The ATVM(Automatic Ticket Vending Machine) of Seoul Metropolitan is a Kiosk which is called Ticket Vending and Reload Device at the subway station. It is implemented for integrating transportation card system which is separated from a paper subway ticket and replacing ticket selling employees. However, since the automatic ticket vending machine was accepted in 2009, there has been confusion of purchasing a ticket. Therefore, it requires improvement of usability. This study, conducts a literature search. Also, the interface of ATVM is analyzed. Finally user observation proceeded at Sinnonhyeon Station of Seoul Metro line 9. The results show that selecting a destination and section fares is confusing process for user. Based on this survey the improvements of UI are proposed to expect advanced directions of the ATVM.

      • KCI등재

        전자저널의 효과적인 관리 및 이용자서비스에 관한 연구: 대학도서관을 중심으로

        이란주,황신혜 한국정보관리학회 2003 정보관리학회지 Vol.20 No.2

        The purpose of this study was to provide suggestions for the effective management and user services of electronic journals in university libraries. In order to do that literature reviews, case studies and survey questionaries were conducted. The case studied involved six university libraries, which were analyzed based on accessing, cataloging and user services. Questionaries consisting of forty-seven items in eight parts, including selection and subscription of electronic journals were distirbuted to the librarians who were in charge of managing electronic journals. Following an analysis on the survey, quidelines for effective management and user services of electronic journals were suggested. 본 연구는 대학도서관에서 전자저널을 효과적으로 관리하고 서비스하기 위한 방안을 모색하는데 그 목적을 두고 있다. 이를 위하여, 문헌조사 및 사례조사를 바탕으로 설문조사를 실시하였다. 선행연구 분석에서는 전자저널과 관련된 다양한 이슈를 중심으로 이론적 배경을 조사하였으며, 사례조사로서 국내외 6개 대학도서관의 웹사이트를 접근, 목록, 이용자서비스 측면에서 분석하였다. 그리고 대학도서관에서 전자저널을 담당하고 있는 사서들을 대상으로 전자저널의 선정 및 구독 현황을 비롯하여 크게 8개 항목으로 47개의 문항으로 구성된 설문조사를 실시하였다. 연구 결과를 바탕으로 대학도서관에서 전자저널의 효과적 관리 및 서비스를 제공하기 위한 8가지 가이드라인을 제시하였다.

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