http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
졸피뎀 중독 후 발생한 횡문근융해증에 의한 급성 신손상 1예
김홍익 ( Hong Ik Kim ),조성호 ( Seong Ho Jo ),홍효림 ( Hyo-lim Hong ),이인희 ( In Hee Lee ),안기성 ( Ki Sung Ahn ),강건우 ( Gun Woo Kang ) 대한내과학회 2016 대한내과학회지 Vol.90 No.6
졸피뎀은 부작용이 드문 안전한 약제로 알려져 있으나 과량 복용할 경우 횡문근융해증과 같은 심각한 합병증이 유발될 수 있다. 이에 저자 등은 자살목적으로 고용량의 졸피뎀복용과 관련된 횡문근융해증에 의한 급성 신손상을 진단하였고 수액 치료 및 혈액투석 치료로 호전된 증례를 경험하였기에 문헌고찰과 함께 이를 보고하는 바이다. Zolpidem (Stilnox®, Handok, Seoul, Korea) is a hypnotic imidazopyridine that is often used to treat insomnia because it has less abuse and addiction potential than benzodiazepines. Its side effects include headache, dizziness, and nausea, but these are mild. Zolpidem intoxication rarely has severe complications. Here, we report a case of acute kidney injury due to rhabdomyolysis related to zolpidem. A 51-year-old man was admitted with drowsy mentality after taking an overdose of zolpidem in a suicide attempt. Laboratory findings showed a blood urea nitrogen of 59.9 mg/dL, serum creatinine of 5.8 mg/dL, and creatine phosphokinase of 16,210 IU/L. Acute kidney injury associated with rhabdomyolysis complicating zolpidem intoxication was diagnosed. The patient was managed with hemodialysis and recovered completely in terms of renal function and muscle enzyme levels. (Korean J Med 2016;90:550-553)
만성 신질환을 가진 다운 증후군 환자에서 발생한 노르웨이 옴 1예
이인희 ( In Hee Lee ),강건우 ( Gun Woo Kang ),김병규 ( Byong Kyu Kim ),홍효림 ( Hyo Lim Hong ),정기훈 ( Ki Hun Chung ),정현 ( Hyun Chung ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.6
Purpose: Norwegian or crusted scabies is a rare, highly contagious atypical form of scabies caused by the mite Sarcoptes scabiei var. homonis. It is usually associated with advanced age, immunosuppression, physical debility, and developmental disabilities. We report here a case of Norwegian scabies in an institutionalized patient with chronic kidney disease (CKD) and Down syndrome. A 56-year-old male presented at our department with pruritic rash and general weakness of 2 months` duration. Examination showed hyperkeratotic, scaly, crusted erythematous plaques on the hands, trunk, and back of the patient. The microscopic examination of the skin scales with potassium hydroxide demonstrated numerous scabies mites. The patient was treated with hemodialysis and repeated applications of 1% lindane lotion for 2 weeks. He reported significant relief of pruritus and resolution of the skin lesions after the treatment. In addition to uremic pruritus, infectious skin diseases such as Norwegian scabies should be considered in the institutionalized patients with advanced CKD and resistant pruritus.
대유행 인플루엔자(H1N1 2009) 치료에서 Oseltamivir내성을 보인 1예
홍효림,김지헌,이화중,권현희 대한감염학회 2010 감염과 화학요법 Vol.42 No.2
In April 2009, the first swine origin pandemic influenza (H1N1 2009) infection was reported in Mexico and United states and has since spread rapidly worldwide. Finally on June 11, 2009, WHO officially declared the first pandemic of the 21st century. Until March 2010, more than 213 countries reported laboratory confirmed cases of pandemic influenza H1N1 2009, including at least 16,931 deaths. The drug of choice for treatment and prophylaxis of pandemic (H1N1) 2009 influenza are the neuraminidase inhibitor (oseltamivir and Zanamivir). However, increased use of these drugs lead to the emergence of oseltamivir-resistant strains. We report a case of oseltamivirresistant pandemic influenza (H1N1 2009) virus infection in a patient who were initially started with oseltamivir for laboratory-confirmed influenza. Patient's symptoms worsened despite the use of high-dose oral oseltamivir, and antiviral susceptibility test showed oseltamivir resistance (H275Y mutation). The patient resolved after treatment with zanamivir.