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      • KCI등재

        수은 폭로 근로자의 혈중 Zinc - Protoporphyrin 및 혈청 Cholinesterase Activity 에 관한 조사 연구

        홍두루미,김광종,김종연 한국산업위생학회 1993 한국산업보건학회지 Vol.3 No.1

        This study aims at investigating the relationships between the urinary mercury concentration and blood zinc-protoportphyrin, serum cholinestrase activity, making 149 workers exposed to mercury vapor and 68 workers who were not exposed to mercury among the workers in a flurorescent lamp manufactureing factory an object of this investigation. The results are as follows ; 1. In an exposed group, the number of those whose urinary mercury concentration showed over 1.00 ㎍/ℓ was 21 persons (14.3%) among 147 workers. The average urinary mercury concentration was 52.1±146.1 ㎍/ℓ(1.8-361.2 ㎍/ℓ), which proved to be higher than the average concentration in a control group. 2. In an exposed group, the average concentration of blood zinc-protoporphyrin was 27.8±12.5 ㎍/㎗ (12.2-101.5㎍/㎗), which proved to be somewhat higher than the average concentration in a control group. But it slid not show a significant difference. 3. In an exposed group, the average concentration of serum cholinesterase activity showed 1936.7±341.01U/ℓ (1,120.0-2,875.0IU/1), which proved to be lower than the average concentration in a control group. 4. The relational coefficient between urinary mercury concentration and blool zinc-protoporphyrin, serum cholinesterase activity of the whole workers exposed to mercury showed little difference. While the relational coefficient between the urinary mercury concentration and blood zinc-protoporphyrin of the workers whose urinary mercury concentration showed over 100 ㎍/ℓ was relatively high, which was 0.62.

      • KCI등재후보

        금속수은 폭로 근로자의 일시뇨를 이용한 생물학적 모니터링 평가

        홍두루미,김순덕,염용태,최재욱 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.1

        Biological monitoring for exposure permits estimation of organ doses or body burdens from exposures through all relevant portals of entry. Biological monitoring data may be used to estimate environmental concentrations when the latter cannot be measured directly. Biological indices are usually concentration of a chemical of its metabolites or its effect at the true receptors. Mercury concentration in urine has been most commonly recommended as a biological exposure index of mercury. for data based on urine analysis, variation in urine volume is the most significant. The urinary concentration related to excretion of the solute provides some correction for fluctuation of urine output. Sampling time must be carefully observed because distribution and elimination of a chemical are kinetic events. This study has evaluated mercury concentration in spot urine compared to the results of 24 hour collected urine by the adjustment methods(specific gravity, creatinine) and sampling time. The subjects were 43 workers who had been exposed to the metallic mercury. The results were as follows: 1. The correlation coefficients between mercury concentration in 24 hour urine and that in spot urine were 0.639-0.715 and were not different by adjustment methods. 2. In the high exposure group who were over 100ug/l of urinary mercury, the correlation coefficients between mercury concentration in 24 hour urine and that in spot urine were 0.687-0.824 and were not different by adjustment methods. 3. Mercury concentration in spot urine were very variable by sampling time or exposure time. The correlation coefficients between mercury concentration in 24 hour urine and that in spot urine were most highest as 0.85-0.91 at first voiding urine in the morning, and were 0.77-0.86 at urine collected within four hours before end of shift. In the biological monitoring to exposure of mercury, sampling of spot urine were most proper at first voiding urine in the morning, and then at urine collected within four hours before end of shift. But the adjustment methods of specific gravity and creatinine were no difference of the results.

      • KCI등재

        우리나라 일부 大學生의 健康行爲에 있어 健康信念과 健康 統制位 性向에 관한 硏究

        두루미 韓國保健敎育學會 1988 보건교육건강증진학회지 Vol.5 No.2

        This study was carried out to find the influencing factors on the acceptance of vaccination of viral hepatitis type B. Two groups of student, 362 undergraduates of Korea University were surveyed for research. The compliant group was 156 students who were inoculated with viral hepatitis type B shot more than on time. The non-compliant group was 206 students who were not inoculated. The measures used for this study were Multidimensional Health Locus of Control Scales and the one developed by the research on the basis of literature review about Health Belief Model. The results of this stuby were as follows. The awareness on health of the compliant group was higher than that of the noncompliant group(t=0.39, P<0.05). And perceived barrier of the compliant group was lower than that of the non-compliant group (t=0.35, P<0.05). But the knowledge about the viral hepatitis type B of the compliant group was lower than that of the non-compliant group (t=2.49, P<0.05). There were no differences between two groups in the perceIved susceptibility of the hepatitis and the perceived benifit of the hepatitis vaccination. There was no difference between two groups in terms of the Inner Health Locus of Control(HLOC) and Chance HLOC.On the other hand Powerful-Others HLOC of the compliant group was higher than that of the non-compliant group(t=3.67, P<0.05). 'Parent's advice' was found to be the major answer to the motive of being vaccinated in the compliant group. This explains that the most influencial factor in determining one's health behavior is the parent's opinion. Answers to the question of the reason of not being vaccinated were, 'did not want to bother' and 'did not care yet' in order. As a whole, except for the awareness on health and the perceived barrier of the hepatitis vaccination, this study result shows disagreement with the past investigations on the interrelationship between one's health belief or Health Locus of Control and the health behavior. The author of this study believes this was due to the limitation in the survey group's particular homogenity.

      • SCOPUSKCI등재
      • SCOPUSKCI등재
      • SCOPUSKCI등재
      • 一部 大學生의 B型肝炎 感染에 關한 疫學的 調査硏究

        南貞祐,廉容泰,두루미 고려대학교 의과대학 1986 고려대 의대 잡지 Vol.23 No.1

        Modern serologic techniques for the detection of HBsAg and Anti-HBs, particularly radioimmunoassay(R1A) and enzyme immunoassay(EIA), provided a technical foundation for more precise and sophisticated epidemiologic studies, of hepatitis B infection. Through a many study it has been revealed that the prevention and the control of hepatitis B infection have emerged as an urgent and serious problem in Korea. However, there are still some arguments on the prevalence rate, mode of transmission, control measures and so on, which hinder the development of certain countermeasures at national level. The authors have conducted this study on a total of 4,125 freshmen of 1983 academic year in Korea University to analyse the prevalence of HBsAg and Anti-HBs positives detected by RPHA and PHA methods in relation to a variety of factors such as socio-demographic, vaccination, family history, personal hygiene, past history of liver diseases and etc. The findings of the study were as follows; 1. Positive rates of HBsAg and Anti-HBs were 7.0 and 19.3% respectively. The rate for male was slightly higher than that of female. 2. In detecting HBsAg, sensitivity of RPHA against RIA method was 91.4% and specificity was 100% whereas sensitivity of PHA method was 51.9% and specificity was 88.9% respectively in detecting Anti-HBs. A question of false negative patient was raised in detecting Anti-HBs by PHA method. 3. Only two percent of HBsAg positive students were found to be acute hepatitis patients as a results of liver function test and 10% of them were thought to be in chronic state. 4. Among Anti-HBs Eegatives, the turn-out rate to positive after three times of vaccination with one of H-B-Vax and Hepavax were 61.0% by PHA method. But it was revealed to be 87.8% after reexamination of Anti-HBs negatives by the method of RIA. 5. The relationship of personal characteristics of subjects with the positive rate of HBsAg and Anti-HBs was analyzed. The communities with small population showed higher rates than ones with large population. For example, Cheju has shown the highest rate and was followed by Cholla Puk-Do and Kangwon-Do. In addition, the results suggested that the appearance of HBsAg and Anti-HBs associated with past history of liver diseases and family history of liver diseases, especially mother's past history. 6. Other factors including housing, past history of vaccination, skin test, acupuncture, behavior such as sharing tooth brush or razor with others and etc., have been reviewed but .there was no significant association with hepatitis B infection.

      • SCOPUSKCI등재

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