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주요우울장애 환자의 자살위험성과 생애초기스트레스 및 회복탄력성 사이의 연관성
허규형,석정호,최원정 대한신경정신의학회 2014 신경정신의학 Vol.53 No.6
Objectives The aim of this study is to investigate the relationship of suicide risk with early-life stress (ELS) and resilience in patients with major depressive disorder (MDD). Methods The participants were 60 patients with MDD and 29 healthy volunteers. Each subject was assessed concerning ELS, resilience factors, suicide ideation, and depressive symptom severity using self-report questionnaires. Mann-Whitney test and stepwise multiple linear regression analyses were performed. Results Emotional abuse, physical abuse, neglect, and exposure to inter-parental violence were higher in the patient group than in the control group. Resilience factors were significantly lower in the patient group. In multiple regression analyses, final regression model including physical abuse, neglect, and self-regulation factor was significant explaining 45.6% variance of suicide ideation score. Conclusion We found that ELS experiences, particularly exposure to inter-parental violence, might be a significant risk factor for development of depression. In particular, experiences of physical abuse and neglect might increase the risk of suicide in depression but resilience may play a protective role in development of depression and prevention of suicide in depressive patients. 생애초기스트레스가 우울증과 관련이 있으며 특히 부부폭력노출이 우울증과 중요한 연관성이 있음을 알 수 있었다. 신체학대와 방임은 우울증 환자에서 자살위험성 증가와 관련이 있었다. 회복 탄력성은 우울증 발병을 예방할 수 있는능력이며 특히 자기조절능력이 우울증 환자에서 자살의 보호요인이 될 수 있겠다. 이 연구 결과가 향후 우울증 환자에서 자살 시도를 예방하는 데 회복탄력성 기반 치료 근거를제공해 줄 수 있을 것으로 생각한다.
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기분안정기 1형 양극성장애 환자의 심상 특성 및 정서 조절
김근유,허규형,오동훈,김성화,유빈,조현상 대한우울조울병학회 2016 우울조울병 Vol.14 No.2
Objectives : We investigated characteristics of mental imagery and its relation to emotion regulation in euthymic patients with bipolar I disorder using self-report measurements. Methods : Fifty euthymic bipolar I patients and 50 healthy control subjects participated. We applied Korean version of Difficulties in Emotion Regulation Scale (KDERS) to assess emotion regulation difficulties. Spontaneous Use of Imagery Scale (SUIS) and Vividness of Visual Imagery Questionnaire (VVIQ) were conducted to assess tendency towards general use and vividness of imagery, respectively. Results : Patients with bipolar I disorder showed significantly lower scores in VVIQ (t=-2.043, p=0.044), but not in SUIS, than healthy participants. Bipolar patients also showed significantly higher scores in KDERS than healthy controls (t=2.091, p=0.039). However, there was no association of the ratings of VVIQ or SUIS with K-DERS, and also no significant relations between characteristics of mental imagery and mood symptom scores. Conclusion : These findings suggest that bipolar patients maintain the high level of vividness in mental imagery despite euthymic mood. However, we couldn’t find any relationships between emotion regulation and mental imagery. More delicate measures, such as specific imagery or emotion regulation tasks, will be needed to demonstrate the relationship of two aspects.
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