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공기 전색증 고양이에서 Norepinephrine, Isoproterenol, Nitroglycerin 이 혈역학 및 혈액가스분석치의 변화에 미치는 영향에 대한 비교
한성민,이일옥,서병태 대한마취과학회 1988 Korean Journal of Anesthesiology Vol.21 No.4
The effects of Norepinephrine (NE), Isoproterenol (ISO) and Nitroglycerin (NTG) on the hemodynamic, arterial and venous blood gas analysis changes in air embolized cats were investigated. Under general anesthesia with Halothane, cats were injected 1 mg/kg of air acutely to decrease mean arterial pressure (MAP) about 30 to 40 percent of control value through superior vena cava. 14 cats were divided into two groups of 7 each (group 1 and 2). group 1 cats received NE and then NE with NTG therapies. IN group 2, ISO and then ISO with NTG therapies were taken. The results were as follows: 1) Hemodynamic changes Group 1: NE increased the MAP from 69±8 mmHg (mean±SD) to 116±14 mmHg (p<0.05), decreased the right atrial pressure (RAP) from 18±4 mmHg to 11±3 mmHg (p<0.05). Combined therapy with NTG decreased the MAP from 116±14 mmHg to 101±10mmHg(p<0.05), the HR from 167±16 beats/min(bpm) to 150±4 bpm (p<0.05), the RAP from 11±3 mmHg to 8±3 mmHg (p<0.05). Group 2: ISO increased the MAP from 81±8 mmHg to 112±14mmHg (p<0.05), and the HR from 152±21 bpm to 190±24bpm (p<0.05). Combined therapy with NTG decreased the HR from 190±24 bpm to 174±19 bpm (p<0.05), the CVP from 14±7 mmHg to 14±3 mmHg (p<0.05), and the RAP from 13±3 mmHg to 12±3 mmHg (p<0.05). 2) Blood gas analysis changes Groiup 1 : NE with NTG combined therapy incrased the arterial oxygen tension from 335±54 mmHg to 372±49 mmHg, decreased the venous CO_2 tension from 52±9 mmHg to 47±4 mmHg. Group 2 : ISO with NTG combined therapy increased the arterial oxygen tension from 344±85 mmHg to 375±50mmHg (p<0.05). (Paired t-test, p<0.05). In conclusion, NE and ISO increased MAP in venous air embolism with mopderately decreased MAP. Inotropic agent with NTG therapy improved arterial oxygenation.
한성민,최신,유영진,김성록,한태희 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2
Objective: This study is aimed to assess the effectiveness and safety of the autologous stem cell transplantation for patients with relapsed aggressive non-Hodgkin's lymphoma(NHL). Methods and Materials: We performed a retrospective analysis of 4 patients with relapsed aggressive NHL who undergone the autologous stem cell transplantation from the Inje University Sanggyepaik hospital. Results: All three patients with diffuse large B cell NHL have been in disease-free status without evidence of relapse for 5∼13 months after transplantation. A patient with extranodal NK/T cell lymphoma expired due to treatment related complications. Conclusion: High dose chemotherapy with autologous peripheral blood stem cell trar splantation(PBSCT) is an effective treatment for relapsed diffuse large B cell lymphoma.
인공고관절 전치환술에서 세라믹 볼 헤드의 기계적 안정성 평가를 위한 유한요소 해석
한성민,추준욱,전흥재,김정성,최귀원,윤인찬,Han, Sung-Min,Chu, Jun-Uk,Chun, Heoung-Jae,Kim, Jung-Sung,Choi, Kui-Won,Youn, In-Chan 대한의용생체공학회 2010 의공학회지 Vol.31 No.6
A ceramic articulating system in total hip replacement thought to be superior to metal-on-polyethylene due to its extremely low coefficient of friction and potential for high resistance to wear. But ceramic is brittle, which makes it mechanically and theoretically susceptible to fracture under certain mechanical conditions. In the current study, nine different models of ceramic ball heads were mechanically evaluated using 3D finite element(FE) analyses. It was found that the maximum stress in all ceramic models was lower than ceramic flexural strength, and it satisfied the requirements of the FDA Gaudience for artificial hip implant. Thus, ceramic ball head models introduced in the current study could be mechanically safe for clinical applications.
한성민 한국농촌경제연구원 2013 해외곡물시장동향 Vol.2 No.1
국제 곡물가격은 연초 유럽 경제 회복 전망과 미국, 중국 등 경제지표와 기업실적 호조, 미국 재정절벽 협상 극적 타결 등 외부시장의 영향으로 전반적인 상품시장 상승세에 동조하는 움직임을 보였다. 일부 펀드를 비롯한 투기세력의 조정물량이 출현하면서 하락압력이 나타나기도 하였으나 기본적인 펀더멘털 강세 상황은 대체로 곡물가격을 지지해주는 역할을 하였다. 옥수수와 소맥 가격에 비해 상대적으로 대두가격은 강세를 보였으며, 이는 미국 대두 수출실적의 호조와 날씨 변수에 따른 남미산 대두 생산량 불확실성이 큰 요인으로 꼽혔으며, 3월말에서 4월초 남미 생산량에 대한 구체적인 수치 발표가 향후 가격 향방에 중요한 모멘텀이 될 것으로 전망된다.
한성민,서병태,우설희 대한마취과학회 1989 Korean Journal of Anesthesiology Vol.22 No.3
Effects of nitroglycerin (NTC), adenosine triphosphate (ATP) and sodium nitroprusside (SNP) on the hemodynamic and blood gas analysis changes epinephrine (EPI) infusion is air embolized cats were investigated. Under the general anesthesia with pentobarbital and vecuronium cats were given 2~2.5 ml/kg of air via internal jugular vein and were resuscitated with EPI bolus injection. Thirty two cats were divided into 4 groups of 8 each. Each 4 groups, were administered saline (group1), NTG (group 2), ATP (group 3) and SNP (group 4) with EPI continuous infusion, respectively. The air shadow in the heart of cats was visualized C-arm image intensifier throught the study and all three vasodilators augmented the removal of air from the heart on C-arm image. All three vasodilators therapy groups produced statistically significant decrease in rate pressure product (p$lt;0.05) but only NTG therapy group decreased heart rate (p$lt;0.05). Central venous pressure were decreased in all three vasodilators therapy groups but only NTG therapy group was statistically significant (p$lt;0.05). Only NTG therapy group increased both arterial (p$lt;0.05) and venous oxgenation. These results indicate that NTG therapy group produced more prominant hemodynamic and blood oxygenation improvement than the other three groups. It is concluded that NTG with vasopressor therapy coude be recommended in venous air embolism.
심부전의 병력 및 완전 좌각불록크(Complete LBBB)가 있었던 환자의 마취관리
한성민,김성덕,김광우,이건일,윤성선 대한마취과학회 1980 Korean Journal of Anesthesiology Vol.13 No.1
A 42-year-old woman who has had the past history of heart failure due to the congestive cardiomyopathy, was scheduled to he taken abdominal hysterectomy. Preoperative electrocardiography showed complete Left Bundle Branch Block(LBBB) without any subjective symptom. The anesthetic managements, pre- and post-operative, as well as intra-operative, were satisfactory.