초전도 벌크를 이용한 베어링기술

최용성,이상헌,Choi, Yong-Seong,Lee, Sang-Heon 한국전기전자재료학회 2006 전기전자재료 Vol.19 No.12

전기화학적 방법에 의한 유전자의 검출

최용성,이경섭,박대희,Choi, Yong-Sung,Lee, Kyung-Sup,Park, Dae-Hee 한국전기전자재료학회 2005 전기전자재료학회논문지 Vol.18 No.6

In this paper, a microelectrode away DNA chip was fabricated on glass slide using photolithography technology. Several probe DNAs consisting of mercaptohexyl moiety at their 5' end were immobilized on the gold electrodes by DNA arrayer utilizing the affinity between gold and sulfu. Then target DNAs were hybridized and reacted with Hoechst 33258, which is a DNA minor groove binder and electrochemically active dye. Cyclic voltammetry in 5mA ferricyanide/ferrocyanide solution at 100 mV/s confirmed the immobilization of probe DNA on the gold electrodes. Linear sweep voltammetry or cyclic voltammetry showed a difference between target DNA and control DNA in the anodic peak current values. It was derived from Hoechst 33258 concentrated at the electrode surface through association with formed hybrid. It suggested that this DNA chip could recognize the sequence specific genes. It suggested that multichannel electrochemical DNA microarray is useful to develop a portable device for clinical gene diagnostic system.

재발성 호흡기 감염과 성장 부전을 보인 IgG 아형 결핍증 1례

최용성,홍정미,나영호,차성호,Choi, Yong-Sung,Hong, Jung-Mi,Rha, Young-Ho,Cha, Sung-Ho 대한소아감염학회 2006 Pediatric Infection and Vaccine Vol.13 No.2

원발성 면역 결핍증에는 항체형성에 영향을 주는 질환이 가장 흔하고 그중 선택적으로 분비성 IgA 결핍이 많으나 IgG 농도가 정상 혹은 증가되어 있는 어떤 환자에서는 4가지의 IgG 아형 중에서 한 두 개 이상의 결핍이 발견된다. 대부분의 환자, 특히 IgG4 결핍증 환자에서 폐구균, 포도구균, 헤모필루스균 등에 의한 부비동염, 중이염, 폐렴 등이 반복된다. 상기 10세 여아는 평소에 잦은 상기도 감염을 앓아 왔고, 결핵성 림프절염으로 약물요법을 시행한 병력이 있으며, 매년 2~3차례 폐렴으로 입원치료를 받아왔다. 키와 몸무게가 모두 3백분위수 미만으로 성장부전(growth failure)가 지속되었다. 2003년 9월 심한 폐렴으로 입원 치료 중에 면역결핍 검사를 시행하였다. IgG, IgM level은 정상이었으나 IgG subclass 2, 3, 4에서 모두 감소된 수치를 보여 IgG 아형 결핍을 보였다. 저자들은 반복적인 호흡기 질환을 앓는 환아에서 성장부전이 동반된 IgG 아형 결핍 1례를 보고하는 바이다. Immunodeficiency affected by antibody formation is most common among primary immuno-deficiencies. Selective IgA deficiency is more common but, one or more IgG subclass level is low or deficient in some patients. Patients with antibody production deficiency are vulnerable to pneumococci, staphylococci and H.influenzae leading to sinusitis, otitis media and pneumonia. A 10-year-old girl had suffered from frequent upper respiratory infections, a history of tuberculous lymphadenitis tuberculosis medication, and frequent pneumonia that requires hospital adimission. Her height and weight were below 3 percentile normal growth as a manifestation of failure to thrive. When she had another severe pneumonia, all the immunologic test was normal at first, and then we checked the IgG subclass levels. Her IgG1 was within normal, IgG2 was very low, IgG3 and IgG4 was not detected. We report a case of IgG subclass deficiency in frequent upper respiratory infection and failure to thrive.

1,559례의 소아 신생검에 대한 고찰 : 단일기관 연구

최용성,김선경,김성도,조병수,Choi, Yong-Sung,Kim, Sun-Kyoung,Kim, Sung-Do,Cho, Byoung-Soo 대한소아신장학회 2006 Childhood kidney diseases Vol.10 No.2

Purpose : To analyse the results of the renal biopsies and the clinical diagnoses of patients who had undergone percutaneous kidney biopsies in the department of pediatrics at Kyunghee University Hospital for 22 years from 1984 to 2005. Methods : We retrospectively reviewed the medical records of 1559 patients and analyzed the chief complaints that led to a renal biopsy, age, sex, histopathologic findings and diagnosis. Routine kidney biopsies were performed by automated gun biopsy guided by real time ultrasonography. The diagnoses were made based on the specimen's light microscopy, immunofluorescence microscopy and electron microscopy findings and clinical symptoms and signs. Results : The mean age of the patients was 10 years with the male to female ratio being 1.3:1. The chief complaints that led to a renal biopsy included hematuria only(753 cases, 48.3%), proteinuria only(125 cases, 8.0%) and hematuria combined with proteinuria(537 cases, 34.4%). The most frequent histopathological finding was primary glomerular disease(75.4%) which included IgA nephropathy(30.1%) and mesangial proliferative glomerulonephritis(27.6 %). Systemic disease comprised 11.4% which included Henoch-$Sch\ddot{o}nlein$ nephritis(10.5%) and lupus nephritis(0.8%). Alport syndrome was found in 1.1% of cases which was attributed to hereditary causes. 628 children(40.3%) visited the clinic due to abnormal school urine screening abnormalities and among these, 237 children had mesangial proliferative glomerulonephritis and 234 children who had IgA nephropathy were managed thereafter. Conclusion : IgA nephropathy and mesangial proliferative glomerulonephritis were the two major forms of primary glomerulonephritis found in Korean children who had kidney biopsies from 1984 to 2005.

자기력과 Random Fluidic Self-assembly에 의한 신규 바이오칩의 개발

최용성,권영수,박대희,Choi, Yong-Sung,Kwon, Young-Soo,Park, Dae-Hee 한국전기전자재료학회 2004 전기전자재료학회논문지 Vol.17 No.6

This paper describes a new constructing method of multifunctional biosensor using many kinds of biomaterials. A metal particle and an array was fabricated by photolithographic. Biomaterials were immobilized on the metal particle. The array and the particles were mixed in a buffer solution, and were arranged by magnetic force interaction and random fluidic self-assembly. A quarter of total Ni dots were covered by the particles. The binding direction of the particles was controllable, and condition of particles was almost with Au surface on top. The particles were successfully arranged on the array. The biomaterial activities were detected by chemiluminescence and electrochemical methods.

유기박막의 전기적 특성 연구

최용성,송진원,문종대,이경섭,Choi Yong-Sung,Song Jin-Won,Moon Jong-Dae,Lee Kyung-Sup 한국전기전자재료학회 2006 전기전자재료학회논문지 Vol.19 No.10

Langmuir-Blodgett(LB)layers of Arachidic acid deposited by LB method were deposited onto slide glass as Y-type film. The structure of manufactured device is Au/arachidic acid/Al, the number of accumulated layers are $9{\sim}21$. Also, we then examined of the Metal-Insulator-Metal(MIM) device by means of I-V. The I-V characteristics of the device are measured from -3 to +3 V. The insulation property of a thin film is better as the distance between electrodes is larger.

소수성 Template를 이용한 DNA칩의 제작

최용성(Yong-Sung Choi),문종대(Jong-Dae Moon),이경섭(Kyung-Sup Lee) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.7

Microarray-based DNA chips provide an architecture for multi-analyte sensing. In this paper, we report a new approach for DNA chip microarray fabrication. Multifunctional DNA chip microarray was made by immobilizing many kinds of biomaterials on transducers (particles). DNA chip microarray was prepared by randomly distributing a mixture of the particles on a chip pattern containing thousands of m-scale sites. The particles occupied a different sites from site to site. The particles were arranged on the chip pattern by the random fluidic self-assembly (RFSA) method, using a hydrophobic interaction for assembly.

정신장애 범죄인에 대한 형사법적 대응체계의 문제점과 개선방안

최용성(Yong Sung Choi) 한국공안행정학회 2023 한국공안행정학회보 Vol.32 No.4

From the murder case at a PC room in Gangseo-gu in 2018 to the recent stabbing incidents at Sillim Station and Seohyeon Station, violent incidents by people with mental disorders (including people with mental disabilities related to various addictions such as alcohol or drugs, or people with mental disabilities equivalent to it) continue to occur, leading to high-risk situations such that blind spots in the social safety net still exist due to the lack of a management and supervision system for people with mental disorders in society. In addition, crimes committed by people with mental disorders have increased significantly since 7,304 cases in 2018, increasing to 8,902 cases in 2021, and the recidivism rate has reached 64.3%, meaning that people are immediately released into society without receiving continuous treatment after the end of treatment custody or treatment order (tentative termination). It has been pointed out that there is no judicial treatment and management system for mentally disabled people who have returned to society. Even though violent crimes committed by the mentally disabled are still emerging as a social problem, criminal justice agencies are not reviewing the causes of the crime of the mentally disabled and moving forward with therapeutic treatment but are instead taking measures that focus on repeated surveillance, isolation, and institutionalization. The current treatment and custody law has no provisions for treatment linkage, cooperation, and collaboration between criminal justice agencies and mental (health) medical institutions for therapeutic treatment. Moreover, as criminal justice agencies focus on surveillance, isolation, and institutionalization due to insufficient legislation on treatment linkage, social concerns that mentally disabled people may be stigmatized as potential criminals are increasing, and the need to prevent crimes by mentally disabled people and improve the criminal legal response system is also increasing. Keeping the above situation in mind, this study reviewed the legislative examples of the United States, Germany, and Japan and the limitations of the criminal legal response system for mentally disordered criminals, focusing on the treatment perspective, such as treatment and custody, under the current Medical Treatment and Custody Act. As a result, the following problems were found: First, a lack of connection between the treatment order after the end of treatment and custody; Second, the absence of maintenance and management after the end of the treatment order; Third, the absence of mandatory diagnosis before the execution of the treatment order, and Fourth, a lack of connection and cooperation between the criminal justice system and the mental (health) medical system, and Fifth, the reduction of the target of treatment orders leads to more violent crimes. Therefore, to solve this problem, it is necessary to 'improve' criminal legal response measures, such as harmony and cooperation between the criminal justice system under the Medical Treatment and Custody Act and the mental (health) medical system under the Mental Health and Welfare Act, and more effective treatment of criminals with mental disorders. Accordingly, revision of the Medical Treatment and Custody Act and related criminal law amendments were presented as improvement and legislative measures. However, to more effectively achieve the criminal policy purpose of preventing crimes by mentally disabled people and preventing recidivism within the legislative system between criminal justice and mental (health) medical care proposed in the amendment to the Medical Treatment and Custody Act, it is judged to introduce the followings measures: First, specialization of therapeutic treatment, second, strengthening the ability to respond to mental health problems, third, the right of probation officers to apply for administrative hospitalization, fourth, 2018년 강서구 PC방 살인사건부터 최근 신림역과 서현역 칼부림 사건까지 정신장애인(알코올이나 마약 등 각종 중독과 연관성 있는 정신장애인 또는 이에 준하는 정신장애인을 포함한다)에 의한 강력사건들이 지속적으로 발생하는 가운데 고위험 정신장애인에 대한 사회 내 관리, 감독 시스템 미비로 사회안전망의 사각지대가 여전히 존재하고 있다. 또한 정신장애인의 범죄는 2018년 7,304건 이후 큰 폭으로 증가해 2021년 8,902건으로 늘고 있고, 재범률도 64.3%에 달하고 있어 치료감호나 치료명령 종료(가종료) 후 지속적인 치료를 받지 않고 바로 사회에 복귀한 범법 정신장애인의 사법적 치료관리 시스템이 부재하다는 지적이 제기되고 있다. 이처럼 정신장애인에 의한 강력범죄 사건이 여전히 사회문제로 부각되고 있음에도 형사사법기관은 정신장애인의 범죄원인에 대해서 치료적 처우를 검토해 나아가는 것이 아닌 기존에 반복되어 왔던 감시와 격리, 시설수용 위주의 대책을 지향하고 있으며, 현행 치료감호법 어디에도 치료적 처우를 위한 형사사법기관과 정신(보건)의료기관 간의 치료연계와 협조, 그리고 협력관계의 규정은 없다. 더구나 치료연계 등의 입법 불비로 인하여 형사사법기관이 감시와 격리, 시설수용 위주의 대책을 지향함에 따라, 사회적으로 정신장애인을 예비적 범죄자로 낙인찍는 데 대한 우려 또한 높아지면서 정신장애인 범죄의 예방 및 형사법적 대응체계 개선의 필요성이 제기되고 있는 상황이다. 본고는 이러한 상황의식을 염두에 두고 현행 치료감호법상에의 치료감호 등 처우관점을 중심으로 미국, 독일, 일본의 입법례와 정신장애 범죄인에 대한 형사법적 대응체계의 한계를 검토해 본 결과, 첫째, 치료감호 종료 후 치료명령의 연계성 부족, 둘째, 치료명령 종료 후 유지 및 관리의 부재, 셋째, 치료명령 집행 전의 의무적 진단사항 등 부재, 넷째, 형사사법체계와 정신(보건)의료체계의 협력관계 부재, 다섯째, 치료명령 대상의 축소가 더 큰 강력범죄로 이어지는 등의 문제점이 있었다. 따라서 이를 해결하기 위해서는 치료감호법상의 형사사법체계와 정신건강복지법상의 정신(보건)의료체계 양 영역 간 조화와 협력 그리고 정신장애 범죄인에 대하여 보다 효과적인 처우 등 형사법적 대응방안의 ‘개선’이 필요한 것으로 보며, 이에 대한 개선 및 입법방안으로써 치료감호법 그리고 이와 관련된 형법 개정안을 제시하였다. 다만, 치료감호법 개정안에서 제시한 형사사법과 정신(보건)의료 간의 입법체계 내에서 정신장애인 범죄의 예방 및 재범 방지라는 형사정책적 목적을 보다 실효적으로 달성하기 위해서는 정신장애 범죄인에 대한 첫째, 치료적 처우의 전문화, 둘재, 정신건강 문제의 대응 능력 강화, 셋째, 보호관찰관의 행정입원 신청 권한, 넷째, 지역사회 내 처우의 강화, 다섯째, 치료적 전문법원의 도입 등이 필요할 것으로 판단된다.

말레에이트계 유기초박막의 가스 반응 특성 분석

崔龍成(Yong-Sung Choi),金正明(Jung-Myoung Kim),金道均(Do-Kyun Kim),權寧守(Young-Soo Kwon) 대한전기학회 1999 전기학회논문지C Vol.48 No.6

온라인 부분방전 감시 시스템

최용성 (Yong-Sung Choi ),황종선 (Jong-Sun Hwang ),이경섭 (Kyung-Sup Lee ) 대한전기학회 2008 대한전기학회 학술대회 논문집 Vol.2008 No.7