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      • KCI등재후보

        증례 : 소화기 ; Lactococcus Lactis에 의한 간농양 1예

        천광진 ( Kwang Jin Chun ),이동규 ( Dong Gyu Lee ),박명옥 ( Myoung Ok Park ),강창돈 ( Chang Don Kang ),이성준 ( Sung Joon Lee ),최대희 ( Dae Hee Choi ) 대한내과학회 2009 대한내과학회지 Vol.77 No.5S

        이전에는 건강한 성인에서 병원균으로 인식되지 않던 Lactococcus가 최근들어 국외에서 간농양, 소뇌농양, 괴사성 폐렴 및 관절염 등을 일으켰다고 보고되었다. 하지만 아직까지 국내에서는 이 균으로 인한 간농양이 보고되지 않았다. 본 저자들은 Lactococcus lactis로 인한 간농양 1예를 경험하였기에 보고하는 바이다. Lactococcus lactis, a facultative anaerobic, Gram-positive bacterium, is not considered a major pathogen in humans, especially in immunocompetent hosts. However, this species can, on rare occasions, cause cerebellar abscesses, endocarditis, necrotizing pneumonitis, and liver abscesses. We present the case of a previously healthy 43-year-old woman with a liver abscess caused by Lactococcus lactis spp. lactis. In addition, the patient had brain and tubo-ovarian abscesses. She was treated successfully with percutaneous abscess drainage and adequate antibiotics. To our knowledge, this is the first case of a liver abscess due to Lactococcus lactis in Korea. (Korean J Med 77:S1128-S1132, 2009)

      • SCOPUSKCI등재

        중환자에서 발견되는 저혈압을 동반한 원인 불명의 다뇨와 나트륨뇨

        천광진 ( Kwang Jin Chun ),이동규 ( Dong Kyu Lee ),백현정 ( Hyun Jung Baek ),김상욱 ( Sang Wook Kim ),정해혁 ( Hae Hyuk Jung ) 대한신장학회 2009 Kidney Research and Clinical Practice Vol.28 No.6

        Purpose: We observed excessive renal excretion of salt and water, without underlying renal diseases or definite causes, accompanied with severe hypotension in critically ill patients. This study investigates the clinical courses and characteristics of these patients. Methods: We retrospectively analyzed 13 patients with polyuria of unknown origin, which persited equal to or longer than 3 days, among hypotensive patients, who were admitted to intensive care unit. Results: The causes of hypotension included sepsis in 11 patients and adrenal insufficiceny in one patient. The cause of hyptension was unknown in one patient. Vassopressors were used in all patients, and hypotension persisted for 13.2±8.6 days. Polyuria persisted for 10.6±8.2 days, and the duration of polyuria was strongly correlated with that of hypotension (R=0.919, p<0.001). Low dose steroid was used in 8 patients for the treatment of hypotension, and hypotension improved in 3 patients within 2 days after steroid administration. Four patients died during the hosptialization, and the duration of hypotension in non-survivors was greater than that in survivors (21.2±9.7 days and 9.6±5.2 days respectively, p=0.020). Conclusion: In critically ill patients with severe hypotension, we observed 13 cases of inappropriate natriuresis and polyuria. These results suggest that the persistence of poyluria and hypotension might affect the prognosis of these patients, and adrenal insufficicieny might be associated with this appearance in some patients. Further studies are needed to establish causes and treatments for this appearance.

      • KCI등재

        증례 : 소화기 ; 복부 대동맥류에 의한 대동맥십이지장루 및 척추 미란 1예

        이동규 ( Dong Gyu Lee ),천광진 ( Kwang Jin Chun ),최대희 ( Dai Hee Choi ),강창돈 ( Chang Don Kang ),이성준 ( Sung Joon Lee ),이길수 ( Kil Soo Yie ),김형래 ( Hyung Rae Kim ) 대한내과학회 2010 대한내과학회지 Vol.78 No.1

        국내에서는 아직 복부 대동맥류에 의해 대동맥십이지장루와 척추 미란이 함께 동반한 경우는 보고된 바가 없다. 저자들은 토혈을 주소로 내원한 43세 남자 환자에서 반복적 상부 내시경으로 원발성 대동맥십이지장루를 진단하여 수술을 통해 성공적으로 치료하였던 예를 문헌고찰과 함께 보고 한다. A primary aortoenteric fistula is an uncommon complication of an abdominal aortic aneurysm, but can be fatal due to the high risk of massive bleeding and sepsis. Rarely, an abdominal aortic aneurysm can cause vertebral erosion. We report uncommon complications of an abdominal aortic aneurysm that caused an aortoduodenal fistula and lumbar vertebral erosion. To our knowledge, this is the first case of an abdominal aortic aneurysm complicated by an aortoduodenal fistula and vertebral erosion simultaneously. (Korean J Med 78:99-103, 2010)

      • 혈청 칼슘 농도가 담즙내 칼슘 농도의 변화에 미치는 영향

        조병채,김영진,박용검,지경,이정효,장인택,김상준,한기정,광진 중앙대학교 의과대학 의과학연구소 1998 中央醫大誌 Vol.23 No.1

        The purpose of this study was to investigate the relationship between the increased serum calcium changes induced by short-term intravenous calcium infusion and the resultant subsequent changes on total and ionized calcium concentration [Ca_TOT] and [Ca^2+]level, and on bile acid changes in the T-tube bile. Ten patients underwent cholecystectomy, common duct exploration, and T-tube insertion. Serum and biliary calcium concentration were measured over an 7-hour period, before, during, and after a 4-hour intravenous infusion of 10% calcium gluconate. During the infusion, serum total calcium[Ca_TOT] increased from 2.17±0.27 mmol/L to 2.30±0.22 mmol/L and serum free ionized calcium[Ca^2+] increased from the preinfusion state, 1.29±0.10 mmol/L to 1.34±0.15 mmol/L. After the infusion, 60 minite later, biliary total calcium [Ca_TOT] increased from 1.54±0.23 to 1.95±0.37 mmol/L and biliary ionized calcium [Ca^2+] increased from 1.08±0.18 to 1.20±0.09 mmol/L. When the data pooled, increased serum total calcium[Ca_TOT] showed significant correlation with serum ionized calcium[Ca^2+] And also serum ionized calcium[Ca^2+] correlated with biliary total calcium[Ca_TOT] And as to bile acid, increased biliary ionized calcium[Ca^2+] related to decreased bile acid. These results support the hypothesis that calcium is freely permeable at biliary excretory system, and that serum ionized calcium level is one of the determinant elements of biliary calcium level.

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