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차경렬,김찬형,Cha, Kyung Ryeol,Kim, Chan-Hyung 대한생물정신의학회 2007 생물정신의학 Vol.14 No.1
Virtual reality technology is now being used in neuropsychological assessment and real-world applications of many psychiatric disorders, including anxiety disorders, schizophrenia, child psychiatric disorders, dementia, and substance related disorders. These applications are growing rapidly due to recent evolution in both hardware and software of virtual reality. In this paper, we review these current applications and discuss the future work of clinical, ethical, and technological aspects needed to refine and expand these applications to psychiatry.
홍창형(Chang Hyung Hong),차경렬(Kyung Ryeol Cha),오병훈(Byoung Hoon Oh) 대한노인정신의학회 2003 노인정신의학 Vol.7 No.2
Frontotemporal lobe dementia have been underevaluated because of various clinical features, changing diagnostic criteria, and indifference of clinicians. It is important that frontotemporal lobe dementia patient showing behavioral and lingual problems should be early diagnosed and treated. Because frontotemporal lobe dementia patients often confused with Alzheimer's disease, senile depression, schizophrenia, drug abuse. We have presented a case of frontotemporal lobe dementia. He had typical clinical history and symptoms which deserve to be considered frontotemporal lobe dementia. He showed appropriate findings of frontotemporal lobe dementia in the neuropsychological tests and brain magnetic resonance imaging and single photon emission computed tomography. This case is thought to be helpful for clinicians to give attention to early diagnosis and appropriate treatment of frontotemporal lobe dementia.
차경렬,김찬형 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.2
Evidence-based medicine (EBM) has been defined as the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients. RBM could be a meme in medicine that is transferred from one clinical filed to another. The knowledge base that informs clinical decision has been growing with a very rapid pace making it a difficult challenge for the busy clinician to keep up with this growing and high volume of research findings. To keep up to date with the best research evidence, clinicians need a set of strategies. EBM may be the solution of this challenge. The term, Evidence-Based Psychiatry (EBP) was introduced by Elliot Goldner and Dan Bilsker in 1995. The purposes of this review are to introduce EBP and to find the best way to adopt the evidence-based approach to the practice of psychiatry in Korea. For these purposes, we reviewed the practice of EBM and discussed the application of EBP in Korean psychiatric field of medicine.
한국판 대칭 및 정리정돈 성향 척도(K-SOAQ)의 표준화 연구
차경렬,임준석,박준영,이수영,김광욱,노대영,김세주,구민성,김찬형 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.3
Objectives : The Symmetry, Ordering and Arranging Questionnaire (SOAQ) has been reported as a valid tool for the assessment of symmetry, ordering and arranging compulsive behaviors of patients with obsessive compulsive disorder. It was introduced by Radomsky and Rachman in 2004. The aim of this study was to assess the reliability, validity and psychometric properties of the Korean-version of the SOAQ (K-SOAQ). Methods : Two hundreds twenty eight under-graduate college students were enrolled in this study. They were assessed with K-SOAQ, Obsessive-Compulsive Inventory-Revised (OCI-R), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). Statistical analysis was done using calculation of Cronbach’s alpha, Spearman Correlation Coefficient and Principal Components Analysis. Results : There were no significant differences in sex, education, and total scores of BDI and BAI. The Cronbach’s alpha coefficient of K-SOAQ was high, Cronbach’s α=0.96. There was strong evidence for a one-factor solution, accounting for 60.3% of the variance. Convergent validity was examined through correlations between the SOAQ and the OCI-R (r=0.61). Divergent validity was examined through correlations between the SOAQ and two self report measures; BDI (r=0.12) and BAI (r=0.19). Conclusion : The K-SOAQ showed good reliability and validity for the assessment of severity of compulsive characteristics regarding symmetry, ordering and arranging. The K-SOAQ is a useful instrument for assessing compulsive symptoms related with symmetry, ordering and arranging in Korea.
차경렬,김찬형 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.6
Psychiatrists and pharmaceutical industry have a shared interest in advancing medical knowledge. Nonetheless, they also create opportunities for conflict of interests. The primary interest of the psychiatnst is to promote the patient's best interests, while the primary interest of industry is to promote profitability. This paper explores the content of ethical documents most relevant to the biomedical researcher and guidelines related to the ethics of sponsored research. Subsequently, it discusses the ethical quandaries involved and offers solutions for ethical business relationships.
한국판 Neuropsychiatric Inventory로 본 치매 단계에 따른 행동ㆍ정신증상 특징
오병훈,차경렬,홍창형,김지혜 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5
Objectives : This study aimed to compare the behavioral psychological symptoms of dementia by stages and to suggest the proper management treatment plan. Methods : We examined behaviral psychological symptoms in 17 dementia patients with mild stage (CDR=0.5, 1), 18 de-mentia patients with moderate stage (CDR=2) and 24 dementia patients with severe stage (CDR=3, 4). We compared the prevalence and the composite scores (frequency x seventy) of each behavioral domain in K-NPI among three groups. The MMSE-K, GDS, Barthel ADL were also administrated to evaluate the general cognitive function, seventy of the patients and activity of daily living. Results : The most common behavioral disturbances were apathy/indifference, depression/dysphoria, and aberrant motor behavior. The mean composite score of aberrant motor behavior increased by stages of dementia severity with statistical significance. The total score of the K-NPI increased with severer stages of dementia the result didn't show statistical significance. The K-NPI score showed the positive correlation with CDR, GDS and the negative correlation with MMSE-K, B-ADL. But, there was no statistically significant correlation. Conclusion : Behavioral and Psychological Symptoms of Dementia (BPSD) change by the stages of dementia. The practical guideline for BPSD management according to dementia stage is needed. Re-evaluation and new therapeutic inter-vention must be considered by the stages of dementia.
홍창형,김은아,정해관,이동우,차경렬,이강수,오병훈 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4
Objective : The purpose of this study is to find out the effect of ApoE genotype in correlation between metabolic syndrome and cognition of the elderly in the community. Methods : A total of 1,305 subjects (440 men and 865 women) aged 60-98 years were analyzed from preliminary data of Gwangju Dementia and MCI Study (GDEMCIS). The metabolic syndrome was assessed as defined by the modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III). The study questionnaire consisted of demographic characteristics, current and past illness history, drug history, family history of dementia and stroke, and Korean version-Mini Mental State Examination (K-MMSE). We also examined ApoE genotype and analyzed associated factors with metabolic syndrome. Results : Metabolic syndrome was present in 28.6% of the subjects (13.4% of men and 36.3% of women). On multiple logistic regression analysis, low serum HDL cholesterol was associated with an increased risk for cognitive impairment (K-MMSE score≤17) adjusted by age, sex, educational level, and smoking in the presence of ApoE ε 4 allele (OR 0.95, 95% CI 0.92-0.99). Conclusion : These results suggest that serum HDL cholesterol may affect cognitive function in the elderly in the presence of ApoE ε 4 allele.