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조한수 ( Jo Han Su ),김학양 ( Kim Hag Yang ),송영림 ( Song Yeong Lim ),윤호성 ( Yun Ho Seong ),김희선 ( Kim Hui Seon ),고창옥 ( Go Chang Og ),최진욱 ( Choe Jin Ug ),이자영 ( Lee Ja Yeong ),김경호 ( Kim Gyeong Ho ),박준용 ( Park Ju 대한소화기학회 2004 대한소화기학회지 Vol.43 No.2
Gastrointestinal leiomyomas are commonly found in the stomach, and but 3% of them arises from the colon. Colonic leiomyomas are often found incidentally during colonoscopic examination. Most of patients with colonic leiomyoma are asymptomatic, but patients with large size leiomyoma occasionally have abdominal mass, hemorrhage, intestinal obstruction or perforation. Pedunculated leiomyomatous polyp is rare. Leiomyomatous polyps are occasionally misjudged as adenomatous polyps by endoscopist. We report a case of pedunculated leiomyomatous colonic polyp in 65 year-old female patient. She has complained of intermittent hematochezia and lower abdominal discomfort for 5 months. During colonoscopy, an 1㎝ sized long pedunculated polyp at the splenic flexure was detected. It was removed by colonoscopic snare polypectomy. Leiomyomatous polyp was confirmed by micro-scopic and immunohistochemical findings. (Korean J Gastroenterol 2004; 43:129-132)
복막투석 환자에서 음낭부종으로 발현된 샅굴 헤르니아 2예
이정현 ( Jung Hyun Lee ),윤현성 ( Hyun Sung Yoon ),조한수 ( Han Su Cho ),이응준 ( Eung Jun Lee ),유영범 ( Young Bum Yoo ),박정환 ( Jung Hwan Park ),이종호 ( Jong Ho Lee ),송종오 ( Jong Oh Song ),조영일 ( Young Il Jo ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.4
Scrotal edema may develop during continuous ambulatory peritoneal dialysis (CAPD). The two etiologic mechanisms are peritoneo-scrotal communication through a patent processus vaginalis or extravasation of dialysate through a defect of abdominal wall. We report two cases of scrotal edema due to inguinal hernia by peritoneo-scrotal communication during CAPD. The etiology of scrotal edema was confirmed by peritoneal scintigraphy and/or computed tomography. Scrotal edema due to inguinal hernia was completely resolved by a surgical repair of hernia and did not recur despite of resumption of peritoneal dialysis.
실크 피브로인/젤라틴 하이브리드 지지체의 제조 및 특성분석
김혜린(Hye Lin Kim),홍민성(Min Sung Hong),김수진(Su Jin Kim),조한수(Han Su Jo),유일수(Il Sou Yoo),이동원(Dong Won Lee),강길선(Gil Son Khang) 한국고분자학회 2011 폴리머 Vol.35 No.5
실크 피브로인은 생체적합성과 비독성 및 비면역 특성을 갖는 생분해성 천연고분자로서, 콜라겐의 가수분해로부터 유래되는 천연물질인 젤라틴을 이용하여 실크 피브로인/젤라틴 지지체를 제조하였다. 지지체의 최적화 조건을 찾기 위하여 실크 피브로인의 양과 젤라틴 및 글루타알데히드의 농도를 다르게 하여 제조하였다. 실크 피브로인/젤라틴 지지체는 SEM과 DSC 및 수분흡수성 평가를 통해 특성분석을 하였으며 세포생존율 및 증식률은 WST 방법을 통해 평가되었다. 이 결과 실크 피브로인 0.3 g 지지체에 8% 젤라틴 및 1% 글루타알데히드를 함유한 지지체에서 세포 부착 및 증식을 위해 가장 적합한 특성을 제공한다고 제안되었다. 결과적으로, 실크 피브로인/젤라틴 지지체는 잠재적인 세포 전달체 및 조직공학을 위한 구조 기반역할을 할 수 있을 것으로 사료된다. Silk fibroin is a biocompatible and slowly biodegradable natural polymer. This natural polymer has excellent mechanical properties, non-toxicity, and non-immunogenic properties and has been demonstrated to support tissue regeneration. Also, gelatin is a natural material derived from collagen by hydrolysis and has an almost identical composition as that of collagen. Silk fibroin/gelatin scaffolds have been fabricated by using the freeze-drying method. To establish the scaffold manufacturing condition for silk fibroin and gelatin, we made scaffolds with various compositions of gelatin, glutaldehyde and silk fibroin. The silk fibroin/gelatin scaffolds were characterized using SEM, DSC, and water absorption ability tests. The cellular proliferation was evaluated by WST assay. These results suggested that a scaffold containing 8% of gelatin, 1% of glutaldehyde and 0.3 g of silk fibroin provided suitable characterstics for cell adhesion and proliferation. In conclusion, the silk fibroin/gelatin scaffold may serve as a potential cell delivery vehicle and a structural basis for tissue engineering.