학부모 교육권의 법리적 분석과 쟁점 사례 연구

조정제 강원대학교 1998 국내석사

소자본창업의 성공요인에 관한 연구 : 중소규모 레스토랑(음식점)을 중심으로

조정제 昌原大學校 經營大學院 2004 국내석사

The purposes of this study are followings: First, we are to try to access to theoretical concepts by considering theory of starting business with little capital and various literatures on the present condition of small-medium restaurants. Second, we are to identify factors which have an effect on success of starting business with little capital based on analyzed results of existing researches and explain the interrelation among various factors. Third, we are to verify research hypotheses. Fourth, we are to show potential enterprisers practical implications which help promote successful businesses and elicit effectiveness and overcome of starting businesses by analyzing success factors of starting businesses with little capital using results of researches. The results of research hypotheses are followings. First, success factors starting businesses including psychological features, selection of business items, management factors, and image of stores have a positive effect on factors of coping with circumstance. Second, factors of coping with circumstance that are proper compensation, polite apology, solving problems, and advance prevention of problems have a positive effect on business performance. Third, success factors of starting businesses including psychological features, selection of business items, management factors, and image of stores have a positive effect on business performance. Managerial implications of this study are followings: First, founders' psychological states are primarily the most important to bring steady increase in sale after starting businesses with little capital. They should make efforts constantly to obtain excellent overcome and achieve fixed goals, making decisions carefully against scattered unexpected problems. Second, the results of this study show that business items are not directly related to business performance. Therefore, it is necessary to find success factors from external elements as business items are so sensitive of trend. Third, considering factors of management, even small stores need basic management and operation which design, carry out, and control them. Companies should consider constantly consumers' demands and reduce the cost through innovative management as the purpose of companies, large or small is to make profits from customers' satisfaction. Fourth, first impression of the newly emerging store has an important effect on consumers. Though the store is located unfavorably because of the lack of capital, we should use a long-term strategy which gives consumers a good image through a steady publicity. Especially, we should try to provide a good image of store management, differential products and services that make a lasting impression on consumers. Fifth, considering factors of coping with circumstance, it is actually impossible to prevent against possible problems in advance, though it is the best policy in delivering services. Therefore, we should make efforts to open failures of delivering services and solve these problems instead to look over them so that consumers consider the store as devoted and credible as a long-term positive effect on business performance.

우리나라 港灣産業 發展戰略에 관한 硏究

조정제 釜慶大學校 經營大學院 2005 국내석사

공개키 암호에 대한 연구

조정제 인제대학교 교육대학원 2004 국내석사

비밀정보를 보호하기 위하여 암호를 이용하여 메시지를 전달하는 방법을 사용한 것은 역사적으로 매우 오래 전부터 이루어져왔다. 정보 기술의 급격한 발전과 더불어 컴퓨터와 통신 시스템에 기반한 산업구조의 변화가 이루어지면서 개인 정보에 대한 보안의 필요성이 대두되기 시작하였고 암호기법의 도입이 산업 전 분야에 확산되는 계기가 되었다. 단순한 산술적 개념을 이용한 고전 암호학의 개념을 뛰어넘어 수학적으로 풀기 어려운 문제들을 이용하는 기법들이 제안되기 시작한 것이 현대암호학의 큰 특징이다. 특히 1976년 발표된 공개키 암호개념에 수학적인 개념들이 접목되기 시작하면서 현대암호학의 기틀이 마련되었다. 공개키 개념에 구체적인 수학이론이 접목된 암호기법으로 RSA 공개키 암호, ElGamal 공개키 암호 등을 예로 들 수 있다. 이에 본 논문은 이산수학의 중요한 주제인 알고리즘 영역 중 정수론의 기초적인 내용과 관련된 공개키 암호의 기초적인 이론을 연구하고 지도하는 방안에 대한 내용으로 구성되어 있다. The technological advances of the digital computer over the second half of the twentieth century have resulted in several changes in all parts of the mathematical sciences. And discrete mathematics has now become a major area of mathematics in its own right. Discrete mathematics is a developing subject, owing to its links with computer science, statistics, and algebra. Discrete mathematics is the part of mathematics devoted to the study of discrete objects. Discrete mathematics is an optional subject in the high school under the 7th Mathematics curriculum. And a central theme in Discrete mathematics is algorithmic thinking. Public key cryptosystems have been studied extensively for the past 30 years, and from these studies has emerged a rich and deep theory. The purpose of this thesis is to provide a comprehensive reference book for mathematics teachers and students who need information about some interesting algorithms of public key cryptosystems.

흉부모형을 이용한 폐결절의 검출능 : 디지탈영상과 스크린필름영상과의 비교

조정제 중아대학교 대학원 1987 국내박사

수술 전 화학방사선 요법을 시행하는 식도의 국소 진행성 편평 상피암 환자에서 내시경초음파 통과여부가 예후 인자로서 가지는 의의

조정제 울산대학교 대학원 2014 국내석사

Background: EUS is the most accurate loco-regional staging modality for esophageal squamous cell carcinoma (EC). However, it has been reported that approximately 30% of EC obstructs the lumen and EUS fails to traverse the lesion. This study aimed to investigate clinical significance of EUS on survival outcome of patients with EUS traversable versus non-traversable locally advanced EC treated with preoperative chemoradiotherapy (CRT). Methods: A total of 89 consecutive patients with a locally advanced EC (stage II or III) were included retrospectively. All patients were treated with preoperative CRT, including 53 patients who received preoperative CRT followed by esophagectomy. The CRT regimen consisted of cisplatin-based chemotherapy and radiotherapy delivered concomitantly. Relevant clinical and tumor-specific information were reviewed. Results: Median overall survival in all patients was 32.8 months with 5-year survival rate of 43.8%. In 26 of 89 (29.2%) patients, EUS scope could not pass through EC due to stenosis. These patients with EUS non-traversable EC showed a significantly lower serum albumin level (median, 3.6 vs. 3.9 g/dL; P=0.028), larger tumor length (median, 6.0 vs. 4.0 cm; P=0.002) and higher percentage of stage III disease (65.4% vs. 38.1%; P=0.019) than those with EUS traversable EC. Weight loss and ECOG performance status did not differ between the two groups. Of the 89 patients, 79 (88.8%) completed the planned CRT schedule; 22 of 26 (84.6%) patients with EUS non-traversable EC and 57 of 63 (90.5%) with EUS traversable EC (P=0.426). Univariate analysis identified that weight loss ≥10%, serum albumin level <3.8 g/dL, EUS non-traversability, tumor length ≥5 cm, clinical stage III, non-response to preoperative CRT, and incompletion of planned esophagectomy were negative predictive factors of survival. Weight loss ≥10% (P=0.042), EUS non-traversability (P=0.007), non-response to preoperative CRT (P=0.003), and incompletion of esophagectomy (P=0.002) remained significant negative predictive factors of survival in multivariate analysis. Patients with EUS non-traversable EC had a significantly lower 5-year survival rate than those with EUS traversable EC (30.8% vs. 49.3%, P= 0.023). Conclusion: EUS traversability is a significant predictor of survival in patients with a locally advanced EC treated with preoperative chemoradiotherapy.

토픽 모델과 트랜스포머를 활용한 담화형 문서의 생성형 요약에 대한 연구

조정제 연세대학교 일반대학원 2022 국내석사

ICT 기술 발달에 따라 웹상에서 텍스트 데이터는 꾸준히 증가해왔다. 특히 최근에는 COVID19 등의 상황으로 사회 전반에 비대면 기조가 강화되었고, 다자간 의사소통이 온라인상에서 이루어지면서 다양한 형태의 담화형 텍스트데이터가 양산되고 있다. 일상 및 비일상적인 곳에서 양산되는 텍스트 데이터에 대해 독자가 정보를 효과적으로 취하기 위해서는 텍스트 요약 모델의 필요성이 존재한다. 하지만 일반적인 요약 모델의 경우에 뉴스나 논문 또는 산문 같은 단일 발화자 중심의 텍스트 요약에 초점을 맞추어 개발되어 왔고, 여러 명의 발화자가 등장하는 담화형 텍스트 데이터를 다루는 데 있어서 차별점을 두고 있지 않다. 본 연구에서는 담화형 텍스트 데이터를 효과적으로 요약할 수 있는 생성형(Abstractive) 문서 요약 모델을 개발하는 것을 목표로 한다. 본 목표를 달성하기 위해 수많은 요약문 생성 태스크에서 최고 성능(State-Of-The-Art)의 기반이 되는 BART 모델을 활용하였다. BART 모델에 발화의 흐름을 학습할 수 있는 발화 단위의 어텐션 층을 추가하고 트랜스포머 기반 텍스트 요약 모델의 한계점을 보완할 수 있도록 LDA 기반 주제 모델을 활용하여 모델을 고도화시켰다. 본 연구에서는 담화형 텍스트 데이터 셋인 DialSUMM에 대해 우리가 제안하는 모델이 더 높은 성능을 보이는지 비교 실험을 진행했다. 결과적으로 요약 모델의 평가지표 ROUGE F1 점수 측면에서 다른 순차 대 순차(Sequence to Sequence) 방식 및 자기 회귀(Autoregressive) 방식의 Baseline 모델보다 담화형 데이터를 우수하게 요약할 수 있다는 것을 입증하였다. 하지만, LDA model의 파라미터 최적화 측면에서 다양한 LDA 파라미터에 대한 비교 실험은 후속 연구로 남긴다. As ICT technology develops, text data on the web has increased significantly. In particular, in recent years, the non-face-to-face stance has been strengthened throughout society due to situations such as COVID19, and various forms of discourse-type text have been mass-produced as multilateral communication takes place online. There is a need for a text summary model for readers to effectively take information on text data mass-produced in everyday and extraordinary places. However, in the case of a general summary model, it has been developed with a focus on single speaker-centered text summaries such as news, papers, or prose, and there is no distinction in dealing with discourse-based texts featuring multiple speakers. This study aims to develop a generative document summary model that can effectively summarize discourse-type text. To achieve this goal, the BART model, which is the basis of State-Of-The-Art, was used in numerous summary generation tests. The model was advanced by using the LDA-based thematic model to add an interest layer in speech units that can learn the flow of speech to the BART model and to compensate for the limitations of the transformer-based text summary model. In this study, a comparative experiment was conducted to see if the model we propose was showing higher performance for DialSUMM, a discoursetype text dataset. As a result, it was proved that discourse data can be summarized better than other sequential and autoregressive baseline models in terms of ROUGE F1 scores in the summary model. However, in terms of parameter optimization in the LDA model, comparative experiments on various LDA hyperparameters remain as follow-up studies.

블록체인 기반의 정부 주도형 보이스피싱 대응 시스템 제안

조정제 동아대학교 대학원 2021 국내석사

본 연구에서는 보이스피싱의 형태와 피해현황에 대해 알아보았다. 그리고 정부가 2020년 6월에 금융위원회에서 발표한 보이스피싱 척결 종합방안의 주요내용은 무엇인지 알아보았다. 현재의 정부와 금융기관이 가지고 있는 보이스피싱 대응방안이 어떠한지 분석하고, 문제점을 도출하였다. 그리고, 도출된 문제점에 대한 개선 방안으로 확장성이 용이하고 보이스피싱을 효과적으로 방어할 수 있는 정부주도의 블록체인기반 공동FDS 구축 안을 제안하였다 In this study, we report the types of voice phishing, i.e. phishing attacks mainly using telephony, and amounts of damages in South Korea in recent years. We then summarize the proposal presented in 2020 by the Korean government financial committee to combat the crime. We analyze the government’s proposed countermeasures and identify the problems with the proposal. Based on our findings, we propose a government-led fraud detection system using blockchain technology, that is easy to expand and can be effective in combating voice phishing.

Investigation of Korean red ginseng extracts-drug interaction in diet induced mouse model of non-alcoholic fatty liver disease (NAFLD) : 식이법에 의해 유발된 비알콜성 지방간 마우스 모델에서 홍삼추출물과 다른 약물간의 상호작용 가능성 평가

조정제 경북대학교 대학원 2017 국내석사

비알콜성 지방간은 지방증, 간염 등의 증상을 포함하는 질병으로 이 질병을 가지는 환자수는 해마다 증가하고 있다. 비알콜성 지방간이 유발되게 되면 많은 생체이물의 대사에 관여하는 Cytochrome P450 효소가 저해되게 되어 예상치 못했던 부작용을 일으킬 수 있기 때문에 이 질병의 치료와 예방에 주의할 필요가 있다. 많은 사람들은 비알콜성 지방간뿐만 아니라 다양한 질병을 치료 혹은 예방하기 위해 처방된 약물을 복용하면서 홍삼 추출물과 같은 건강기능식품을 함께 복용하고 있으며, 이와 관련된 부작용의 보고 역시 증가하고 있다. 본 연구에서는 methionine과 choline이 결핍된 식이를 이용해 비알콜성을 지방간을 유도한 마우스에서 홍삼추출물이 현재 처방되는 약물 중 70%의 대사에 관여한다고 알려진 Cytochorome P450 (CYP) 효소의 약물대사에 미치는 영향을 액체크로마토그래피 질량분석기를 이용한 약물동력학 연구를 수행하였다. 그 결과 홍삼추출물의 장기복용이 정상 마우스의 CYP2D의 대사를 저해시키고, CYP3A의 대사를 증가시키는 것을 확인한 뒤 홍삼추출물의 각 성분에 의한 약물대사 변화를 확인할 수 있었다. 비알콜성이 지방간의 유도를 마우스의 간과 혈액을 독성지표와 조직학적으로 관찰함으로써 확인할 수 있었고, 비알콜성 지방간에 의해 저해된 다수의 CYP 효소의 대사가 홍삼추출물을 장기간 복용하게 될 때 회복되는 것으로 나타났지만 농도의존성이 없었기 때문에 그 기전을 확인하기 위한 연구의 필요성을 확인할 수 있었다.

(The) role of Adenosine Deaminase Acting on RNA (ADAR) in gastric cancer

조정제 울산대학교 2018 국내박사

ADAR (Adenosine Deaminase Acting on RNA) is known to mediate deamination of adenosine to inosine through binding to double-stranded RNA (dsRNA), the phenomenon known as RNA editing. To investigate the function of ADAR1 in gastric cancer, RNA sequencing and small RNA sequencing were performed in AGS and MKN-45 cells with stable ADAR1 knockdown. Changed frequencies of editing and messenger RNA (mRNA) and microRNA (miRNA) expression were then identified by bioinformatic analyses. Targets of ADAR1-dependent editing were highly coincident between gastric cancer cell lines and were consistent with candidates from TCGA data. Among several editing target genes, mRNA and protein level of PHACTR4 were increased in ADAR1 knocked-down cells, which occurred due to the loss of seed sequences in the 3′-untranslated region of PHACTR4 that are required for miRNA-196a-3p binding. Subsequent immunohistochemical analyses of tumor samples obtained from gastric cancer patients showed that ADAR1 expression was higher than normal in these samples and was inversely correlated with PHACTR4 staining. On the other hand, decreased miRNA-148a-3p expression in ADAR1 knocked-down cells led to increased mRNA and protein expression of NFYA, demonstrating ADAR1’s editing-independent function. These results suggest that ADAR1 functions in gastric cancer through both RNA editing-dependent and -independent mechanisms. On the other hand, another unique property of ADAR1 is its ability to suppress type I interferon (IFN) response. We therefore sought to determine the specific point(s) where ADAR1 exerts its activity on IFN signaling, and to determine whether the suppression of IFN response is related to its RNA editing function. First, among the components of IFN signaling pathway, we confirmed that protein amount of STAT1 and IRF9 was increased upon ADAR1 knockdown even in the absence of type I or type II IFN in AGS cell. Mechanistically, we found miRNA-302a-3p, the level of which decreases upon ADAR1 knockdown, binds to the seed sequence of IRF9. Consistently, IRF9 UTR reporter level was decreased upon the addition of miRNA 302a-3p, which was ameliorated when seed sequence was mutated. Moreover, treatment of miRNA-302a-3p mimic to ADAR1 knocked-down AGS cell reversed IRF9 or STAT1 protein level to that of control AGS cells. On the other hand, synthetic IFN treatment further increased both un-phosphorylated and phosphorylated STAT1 as well as STAT2 level, the degree of which was lower when ADAR1 was present. Alternatively, we asked whether the mRNA and protein level or localization of MAVS was changed upon ADAR1 knockdown, since the 3’ UTR of MAVS was predicted to be edited. However, mRNA or protein levels as well as the localization of MAVS were not significantly altered upon ADAR1 knockdown. These results suggest that ADAR1 functions in gastric cancer through suppression of STAT1 and IRF9 via miRNA302a-3p, independently from activation or editing of known IFN signaling pathway.