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내시경 완전 절제 후 다발성 간전이로 재발한 저등급 직장 신경내분비종양
조익현 ( Ik Hyun Jo ),이강문 ( Kang-moon Lee ),김대범 ( Dae Bum Kim ),이지민 ( Ji Min Lee ) 대한소화기학회 2020 대한소화기학회지 Vol.76 No.5
The World Health Organization classified rectal neuroendocrine tumors (NETs) as malignant in 2010 owing to their distant metastasis potential. On the other hand, in cases of small rectal NETs (<10 mm), which have a low risk of metastasis, endoscopic removal is the first-line therapeutic option, and regular surveillance is not recommended. The authors report a case of a small, well-differentiated rectal NET, which recurred as multiple hepatic metastases 5 years after apparent complete removal using endoscopic methods. (Korean J Gastroenterol 2020;76:251-255)
총담관 각도가 총담관결석 재발에 미치는 임상적 영향: 메타분석 및 고찰
유성열 ( Seongyul Ryu ),조익현 ( Ik Hyun Jo ),김선후 ( Seonhoo Kim ),김연지 ( Yeon-ji Kim ),정우철 ( Woo Chul Chung ) 대한소화기학회 2020 대한소화기학회지 Vol.76 No.4
Background/Aims: Local and systemic factors, such as diabetes, obesity, and hyperlipidemia, are considered risk factors for the recurrence of choledocholithiasis after successful endoscopic clearance. Local factors include the presence of bile sludge, common bile duct (CBD) diameter, and CBD angulation. Among them, it is unclear if acute CBD angulation is preferable to the recurrence of a CBD stone. Methods: PubMed, EMBASE, CINAHL, the Cochrane Library databases, and google website were searched for randomized controlled trials reported in English and undertaken until August 2019. Meta-analysis was performed on all randomized controlled trials for the recurrence of CBD stones between the patients with acute CBD angulation. Results: Eight randomized trials (1,776 patients) were identified, and the total recurrent rate of CBD stones was 18.8% (334/1,776). A CBD angle ≤145° was significantly associated with an increased risk of recurrent CBD stone (OR=2.65, p<0.01). In two prospective studies, acute CBD angulation was not proven to be associated with a recurrence (p=0.39). Conclusions: Approximately 20% of patients with a CBD stone showed recurrence after the complete clearance of the CBD stone, and a CBD angle ≤145° could increase the risk of recurrence. Overall, a large-scale prospective study should be necessary. (Korean J Gastroenterol 2020;76:199-205)
최윤석 ( Yoon Seok Choi ),반태현 ( Tae Hyun Ban ),조익현 ( Ik Hyun Jo ),목지영 ( Ji Young Mok ),이상빈 ( Sang Bin Lee ),이원직 ( Won Jik Lee ),정성훈 ( Sung Hoon Jung ),오정환 ( Jung Hwan Oh ) 대한췌장담도학회 2014 대한췌담도학회지 Vol.19 No.2
Detection of cystic lesions in the pancreas has increased because of the widespread use of high-resolution diagnostic imaging techniques. Therefore, cystic lesions of the pancreas constitute an increasingly important category with a challenging differential diagnosis. Squamoid cyst of pancreatic ducts is a recently recognized type of cystic lesion in the pancreas in which cystically dilated ducts are lined by non-keratinized squamous epithelium. Although it is clinically known as benign cystic lesion, we experienced its malignant behavior and report here with review of the international literatures.
Rituximab 치료로 호전된 재발성 베게너 육아종증
한지원 ( Ji Won Han ),강귀영 ( Kwi Young Kang ),반태현 ( Tae Hyun Ban ),조익현 ( Ik Hyun Jo ),박성환 ( Sung Hwan Park ) 대한류마티스학회 2014 대한류마티스학회지 Vol.21 No.5
Granulomatosis with polyangiitis (GPA) is a rare antineutrophil cytoplasmic antibody associated with systemic disease characterized by granulomas and vasculitis affecting small and medium vessels. Neurological manifestations in GPA are less frequent than classical manifestations, such as lung and kidney involvement, and cranial nerve palsies are much rarer. Cyclophosphamide and glucocorticoids have been conventionally administered as an initial induction immunosuppressive therapy for GPA. However, increasing evidence has demonstrated the efficacy and safety of rituximab, an anti-B cell monoclonal antibody, for the treatment of GPA. Herein, we describe a successful treatment of relapsing GPA with cranial nerve involvement using rituximab in a 56-year-old male patient who was previously treated with cyclophosphamide plus glucocorticoids.
정민영 ( Min Yeong Jeong ),김진일 ( Jin Il Kim ),김재영 ( Jae Young Kim ),김현호 ( Hyun Ho Kim ),조익현 ( Ik Hyun Jo ),서재현 ( Jae Hyun Seo ),김일규 ( Il Kyu Kim ),정대영 ( Dae Young Cheung ) 대한소화기학회 2015 대한소화기학회지 Vol.65 No.2
Emphysematous gastritis is a rare form of gastritis caused by infection of the stomach wall by gas forming bacteria. It is a very rare condition that carries a high mortality rate. Portal venous gas shadow represents elevation of intestinal luminal pressure which manifests as emphysematous gastritis or gastric emphysema. Literature reviews show that the mortality rate is especially high when portal venous gas shadow is present on CT scan. Until recently, the treatment of emphysematous gastritis has been immediate surgical intervention. However, there is a recent trend of avoiding surgery because of the frequent occurrence of post-operative complications such as anastomosis leakage. In addition, aggressive surgical treatment has failed to show significant improvement in prognosis. Recently, the authors experienced a case of emphysematous gastritis accompanied by portal venous gas which was treated successfully by conservative treatment without immediate surgical intervention. Herein, we present a case of emphysematous gastritis with concomitant portal venous air along with literature review.