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뽕잎, 감초, 솔잎 및 당귀분말이 흰쥐의 혈청조성에 미치는 영향
조영자,허원녕 한국식생활문화학회 2005 韓國食生活文化學會誌 Vol.20 No.1
The purpose of this study was to investigate the effect of dietary Morus alba L.(Bong-ip, B), Glycyrrhizae glabra(Gam-chei, C), Pinus densiflora(Sol-Ip, S) and Angelica gigas(Dang-gi, D)powder on serum composition in rats(Sprague-Dawley male rats, 100-110g). Serum TG(triglyceride, p〈0.01), total cholesterol, glucose, total protein, albumin, GGT(y-glutamyl transferase, p〈0.05) were significantly increased D group than that of nomal and other groups. but UA(uric acid, p〈0.05) was significantly decreased, and C group(p〈0.05)was significantly increased. but C group of urine(p〈0.05)was significantly decreased. Also, B and S groups(p〈0.05) of BUN(blood urea nitrogen). S group(p〈0.05) of ALP(alkaline phosphokinase, B and C(p〈0.05) of CPK(creatinine phosphokinsae, p〈0.05) were significantly increased. B. S and C groups were better than D group for lipid metabolism. and pretection to liver. Also, B and C groups of glucose were same as normal diet. so Mows alba L. was good food for lipid metabolism and hypoglycemic effect.
자색고구마가 사염화탄소 투여에 의한 흰쥐의 간손상 보호에 미치는 영향
조영자,김현아,방미애,오용비,정병춘,문윤호,정우진 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.3
The purpose of this study was to investigate the effects of dietary purple sweet potato(lpomoea batatas) powder on serum lipid levels and antioxidative enzymes in normal and pretective effect on hepatotoxicity rats induced by carbon tetrachlolide. Four groups of rats (3-week-old inbred Sprague-Dawley male rats) were normal rats fed control diet(C)_(1) induced hepatotoxicity rats fed control diet(EC)_(1) normal rats fed purple sweet potato diet(P), and induced hepatotoxicity rats fed purple potato sweet diet(EP). Rats were induced by single injection of 50% carbon tetrachloide(0.1 mL/100 g B.W., i.p.). The rats were fed ad libitum each of the experimental diet for 5 weeks. After 5 weeks the rats were sacrificed and activities of antioxidant enzymes and lipid peroxidation products were determined in their liver homogenates. But serum concentrations of lipid was not significant in all groups. Serum alanine aminotransferase(ALT/GPT) and aspartate aminotransferase(ALT/GPT)of the EC and EP groups were heigher than the C and P groups. The hepatic glucose 6-phosphatase(G9Pase) activity of the group fed purple potato diet(P) was lower than the other groups(p<0.05). However, The glutathione peroxidase(GPx) activities was not statistically different between the groups. Renal glutathione S-transferase(GST) activity of the EC and EP groups were lower than the C and P groups(p<0.05). In conclusion, these results suggest that purple sweet potato is believed to be possible protective effect on hepatotoxicity rats induced by carbon tetrachlolide.