대기부유분진중 nitroarenes 오염도와 그 돌연변이원성에 관한 조사연구 - 서울시 일부지역을 중심으로 -

조성준,최용욱,임영욱,신동천,정용,Jo, Seong-Joon,Choi, Yong-Wook,Lim, Young-Wook,Shin, Dong-Chun,Chung, Yong 환경독성보건학회 1990 환경독성보건학회지 Vol.5 No.3

Nitroarenes are ubiquitous environmental pollutants displaying potent mutagenicity in bacteria and carcinogenicity in mammal. In this study, the concentration of nitroarenes in coarse and fine particles and mutagenicity of POC$\_$N/ fraction was investigated in suspended particulates at the Shinchon and Bulkwang area of Seoul. The suspended particulates were collected bimonthly by a high volume cascade impactor air sampler from July 1987 to May 1988. Extractable organic matter was obtained by ultrasonic extraction on diethly ether/cyclohexane (8/2, v/v). Neutral fraction was obtained by liquid-liquid extraction. Polar neutral organic compounds (POC$\_$N/) was fractionated by thin-layer chromatography. Finally, the concentrations of nitroarenes in POC$\_$N/ fraction were measured and determined by capillary gas chromatography. Direct and indirect mutagenicity of POC$\_$N/ fraction were measured using Salmonella typhimurium TA 98. The result were as follows: 1) Major nitroarenes at the Shinchon area was 1-nitropyrene and at the Bulkwang area it was 2,7-dinitro-9-fluorenone during the year. 2) Average concentration of total nitroarenes measured was 67.26 ng/m$^3$in fine particles which was 1,3 folds higher that in coarse particle (52.30 ng/m$^3$). 3) Annual pattern of nitroarenes concentrations revealed that concentration during heating season (Feb., Jan., Mar.) was 2.2 folds higher than that in non heating season (May, Jul., Sep.). Concentration of each season has 157.68 ng/m$^3$and 80.39 ng/m$^3$. 4) The mutagenic activity of POC$\_$N/ fraction from fine particles was higher compared to that of coarse particles and was increased when metabolically activated, with 59 mixture. Mutagenicities, Metabolically activated, were significantly different between Shinchon and Bulkwang area, 322.8 rev/250 $\mu\textrm{g}$/plate and 286.8 rev/250 $\mu\textrm{g}$/plate, respectively. 5) Annual pattern of mutagenicity of POC$\_$N/ fraction revealed that mutagenicity during the heating season was 1.7 folds higher at Shinchon area and 1.2 folds higher at Bulkwang than during the non heating season. The variable contents and levels of nitroarenes in suspended particulates may affect human health significantly. Further studies such as risk assessment should be conducted on the basis of these kind of studies.

수도권 상수중 유기오염물질의 돌연변이원성

신동천,장재연,조성준,정용,Shin, Dong-Chun,Jang, Jae-Yeon,Jo, Seong-Joon,Chung, Yong 대한예방의학회 1988 Journal of Preventive Medicine and Public Health Vol.21 No.2

To measure the mutagenic activity of micro-organic pollutants in drinking water, mutagenicity test was conducted using Salmnella typhimurium TA 98 strain on the water sample taken from three water supply stations and six tap water in Seoul in July and November 1987. The results were as follows : 1. The average amounts of organic matters in raw, treated, and tap water sampled in July were 0.38mg/l, 0.28mg/l, and 0.45mg/l. respectively, and sampled in November were 0.34mg/l, 0.24mg/l, and 0.22mg/l, respectively. The amount of organic matters of tap water sampled in November did not increase while that of tap water sampled in July increased compare to those of raw or treated water. 2. The amount of organic matters is the highest in neutral fraction compare to acidic and basic fractions. 3. In the five out of six tap water and raw water of Paldang and Kuui station sampled in July, the mutagenicity ratios were greater then two (both direct and indirect mutagenicity). 4. In the three out of six tap water and raw and treated water of Kuui station sampled in November, the mutagenicity ratios were greater than two. 5. While mutagenic activities were low in acidic and basic fraction, they were high in neutral fraction. The samples which had high mutagenic acitivity in the total amount also showed high mutagenic activity in neutral fraction. 6. While mutagenic acitivity was decreased after the treatement of water, it was increased in tap water as the distance from the water supply station increases.

유비쿼터스 센서 네트워크를 위한 부하 분산 AODV 프로토콜

조영준 ( Young Jun Jo ),김성철 ( Seong Chul Kim ),조용범 ( Yong Bum Cho ),조성준 ( Sung Joon Cho ) 韓國航行學會 2007 韓國航行學會論文誌 Vol.11 No.4

서울시 대기중 부유분진의 입도별 돌연변이원성의 월변화

장재연(Jae Yeon Jang),김박광(Bak Kwang Kim),조성준(Seong Joon Jo),정용(Yong Chung) 대한약학회 1988 약학회지 Vol.32 No.5

Monthly variation of mutagenicity by airborne particulate were studied according to particle size of the particulate. Airborne particulates were collected in Shinchon of Seoul which is commocial and traffic area in 1986. And those were separately collected into two parts such as fine particle (less than 2.5mcm aerodynamic diameter) and coarse particle (greater than 2.5mcm). Extractable organic matters(EOM) were extracted and mutagenicity of the EOM was tested in Salmonella thyphimurium TA 98 by Ames method. While the concentration of coarse particle did not show the seasonal variation, that of fine particle showed great seasonal variation. The contents and mutagenicity of EOM in fine particles were higher than those of coarse particles. So fine particles were expected to contribute to the 90% of mutagenicity in atmosphere by suspended particulates. The content of EOM and mutagenicity by suspended particulates in atmosphere were highest in January all the year around and also higher as much as 6 and 30 times than in July, respectively.

폴리실리콘 슬러지 혼입 콘크리트의 조기강도 발현 특성에 관한 연구

이지환(Lee, Ji-Hwan),박희곤(Park, Hee-Gon),박기홍(Park, Gi-Hong),조성준(Jo, Seong-Joon),류영석(Ryu, Young-Seok),이상수(Lee, Sang-Soo) 한국콘크리트학회 2015 한국콘크리트학회 학술대회 논문집 Vol.2015 No.5

식당 종업원의 환경 담배 연기(ETS)의 노출과 머리카락 중 생체지표 연구

조성준 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.2

ETS(environmental tobacco smoke) is composed of exhaled mainstream smoke (MS) from the smoker, sidestream smoke(SS) emitted from the smoldering tobacco between puffs and contaminants that diffuse through the cigarette paper and mouth between puffs. These emissions contain both vapor phase and particulate contaminants. ETS is a complex mix of over 4,000 compounds. This mix contains many known or suspected human carcinogens and other toxic agents. More of these toxic compounds are found in SS than in MS. Workplace exposure to ETS can result in significant smoke intake, and passive smoke exposure may be related to impair respiratory function and an increase risk of lung cancer in nonsmokers. For nonsmokers sharing a work environment with cigarette smokers, the workplace must be considered hazardous independently of any specific industrial toxic exposure. The risk is particularly important when a high percentage of the workers smoke or where smokers and nonsmokers work in poorly ventilated areas. Nicotine is converted in the body to cotinine; cotinine therefore can be used as an indirect measure of a person's recent exposure to tobacco smoke. Levels of nicotine in hair and levels of cotinine in body fluids (saliva and urine) have been shown to increase with increasing environmental nicotine levels and with selfreported ETS exposure. The measurement of nicotine or cotinine in hair may be more appropriate for longerterm exposure to tobacco. The purpose of this study is to comparing airborne nicotine levels and hair cotinine level in restaurant workers. Concentration of airborne nicotine and hair nicotine (and cotinine) is closely related to exposed frequency of sidestream smoke in the workplace. Nicotine in hair is a better predictor of airborne nicotine than hair continine. Hair nicotine can be a useful tool to assess ETS exposure interventions. It may have limiting levels of ETS exposure by placing regulatory restrictions on smoking in workplaces and in public spaces.

VOCs의 위해성 평가를 위한 노출분석 방법 연구

조성준,신동천,정용,이덕희,Patrick N. Breysse 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.2

Volatile organic compounds (VOCs) are an important public health issue in Korea and many important questions remain to be addressed with respect to assessing exposure to these compounds. Because they are ubiquitous and highly volatile, special techniques must be applied in their analytic determination. Valid personal exposure assessment methods are needed to evaluate exposure frequency, duration and intensity, as well as their relationship to personal exposure characteristics. Biological monitoring is also important since it may contribute significantly in risk assessment by allowing the estimation of effective absorbed doses. This study was onducted to establish the environmental measurement, personal dosimetry and biological monitoring methods for VOCs. These methods are needed to compare blood, urinary and exhalation breath VOC levels and to provide tools for risk assessment of VOC exposure. Passive monitors (badge type) and a active samplers (trap) for the VOCs collection were used for air sampling. Methods development included determining the minimum detectable amounts of VOCs in each media, as well as evaluating collection methods and developing analytical procedures. Method reliability was assessed by determining breakthrough volumes and comparing results between laboratories and with other methods. A total capacity of trap used in this study was 60ℓ. Although variable by compound, the average breakthrough was 20%. Also, there was no loss of compounds in trap even if keep for 45 day in -70℃. The recovery of active and passive methods was 69%~126% and method detection limit was 0.24㎍/trap and 0.07㎍/badge. There was no statistical difference (P>0.05) between active and passive methods.

우리나라의 환경문제 우선순위 도출 : 환경전문가를 중심으로

신동천,임영욱,박종연,장은아,김진용,박성은,조성준 한국환경독성학회 1999 환경독성보건학회지 Vol.14 No.4

This study was conducted to analyze the priority of environmental problems in Korea by investigating the environmental professionals' perception. The delphi technique was applied to identify their risk perception towards some specific items related with pollution. A standardized questionnaire on environmental problems and their priorities was used to 74 subjects. In the questionnaire, the environmental problems were divided into the general ones, 9 items, and the specific ones, 30 items. Also, the perception was associated with two points of view which were the risk on general human health or ecosystem, and on the present situation in Korea. The priority of risk from general environmental problems on human health or ecosystem was analyzed in the order of `water pollution', `air pollution', `soil contamination', `waste', `toxic chemical pollutants', `food contamination', `ocean contamination', `odor pollution', and 'noise pollution'. The priority of risk on the present situation in Korea was analyzed in the order of 'water pollution', 'air pollution', 'waste', 'toxic chemical pollutants', 'food contamination', 'soil contamination', 'ocean contamination', 'odor pollution', and 'noise pollution'. And these priorities were significantly related with the characteristics of respondents such as sex, age, and major concerned area. However, for the first five priorities of risk from the specific environmental problems on human health or ecosystem, the environmental professionals agreed with 'automotive vehicle exhaust', 'domestic and industrial source pollutants to surface water', 'CO₂ and global warming effect', 'toxic air pollutant', and 'industrial source air pollution'. The priorities of risk on the present situation in Korea were similar to these results.