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정혜교 ( Hye Gyo Chung ),민양원 ( Yang Won Min ),이찬수 ( Chansu Lee ),홍성노 ( Sung Noh Hong ),원지영 ( Ji Young Won ),장진아 ( Jin Ah Jang ),김철현 ( Cheol-hyun Kim ),장동경 ( Dong Kyung Chang ) 대한소화기학회 2020 대한소화기학회지 Vol.75 No.3
Background/Aims: Dysbiosis is an important factor in the pathogenesis of irritable bowel syndrome (IBS). Several studies have reported promising results using probiotics for the treatment of IBS. This study evaluated the efficacy of novel probiotics isolated from Kimchi, a Korean fermented food, and the feces of healthy Vietnamese people in a murine model of IBS. Methods: Lactobacillus paracasei DK121 was isolated from Kimchi, and L. salivarius V4 and L. plantarum V7 were isolated from the feces of healthy Vietnamese people residing in Korea. Forty rats were allocated to receive one of the study strains, a mixture of the strains, or the vehicle. After 5 days of administration, the rats were restrained in a cage to induce IBS. The effects of the probiotics on IBS were analyzed by evaluating the stool weights and stool consistency scores. Results: The primary outcome was analyzed upon the completion of a three-week experiment. The rats in the V7 group showed lower stool weights than those in the control group at week 2 (median: 1.10 [V7] vs. 2.35 [control], p=0.04, Mann-Whitney U-test) and week 3 (median: 1.10 [V7] vs. 2.80 [control], p=0.017). The rats in the DK121 (median: 2.00, p=0.007), V7 (median: 2.00, p=0.004), and mixture (median: 1.50, p=0.001) groups showed better stool consistency scores at week 2 than the control group (median: 3.00). Conclusions: The novel probiotics have beneficial effects on defecation in a murine model of IBS. Human studies confirming the efficacy are warranted.
김정규(Jung Gyu Kim),정기택(Gi Taek Chung),정혜교(Hye Kyo Chung),백용준(Young Joon Paek) 한국강구조학회 1997 韓國鋼構造學會誌 Vol.9 No.3
Due to the complexity of crane related load estimation and design, process for steel factory has seldom been effectively automated and the adequate design program cannot be easily found. So the design of steel factory mainly depends on the sophisticated calculation by structural engineers. Along with the increasing needs of the largescale factory, the structural design of the factory has required a lot of time and effort in engineering practice. Moreover, because the greater part of the programs currently used in the structural design field have specified functions that are not directly linked to each other, it is likely to cause quite a few errors and reduce efficiency. In this study, the Steel Structure integrated system(SSis) has been developed to integrate the modeller, analysis and post-processor for the steel factory. This program includes a powerful pre-and post-processor through Graphic User Interface(GUI) from the windows 95 platform. and the object-oriented programming is employed to manage the overall process effectively. This program is supposed to update the structural design procedure and contribute to the development of construction technology.
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오진명 ( Jinmyeong Oh ),신동현 ( Dong Hyun Sinn ),성결 ( Gyeol Seong ),정혜교 ( Hye Gyo Chung ),허찬미 ( Chanmi Heo ),유정일 ( Jeongil Yu ),박희철 ( Hee Chul Park ) 대한간암학회 2018 대한간암학회지 Vol.18 No.1
Although first-line treatment option for single, small sized hepatocellular carcinoma in patients with preserved liver function and good performance status is resection or ablation, sometimes these modalities cannot be applied for variable reasons. For them, alternative options such as transarterial chemoeombolization, ethanol injection, and external radiation therapy can be considered, with variable success rates. Herein, we describe 45 year-old male who presented with a single small tumor located at caudate lobe. After multi-disciplinary discussion, the patient was treated with proton beam therapy, which resulted in favorable treatment outcome. (J Liver Cancer 2018;18:80-85)