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준설물을 이용한 폐기물 해양배출 해역의 복원 가능성에 대한 연구
최기영(Ki Young Choi),김창준(Chang Joon Kim),김혜은(Hye Eun Kim),정준모(Jun Mo Jung),정창수(Chang Soo Chung) 한국해양환경·에너지학회 2019 한국해양환경·에너지학회 학술대회논문집 Vol.2019 No.5
서해병 해역에서 2006년 이전에 폐수처리오니의 국지적인 해양배출 집중으로 퇴적물오염이 심화된 지역에 준설물질을 이용한 피복효과를 살펴보았다. 서해병 해역의 경우, 피복이 되지 않은 구역에서는 Cr, Cu, Zn등이 계속 주의기준(TEL)을 초과하고 있으며, 준설물질로 피복된 구역에서는 표층퇴적물에서 4년간 오염물질의 농도변화는 피복이후 감소되어 계속적으로 유지하고 있는 것으로 판단된다. 준설물질로 피복된 구역의 주상퇴적물의 연간변화를 살펴보면, 피복 후 표층에 새로운 퇴적물이 쌓이고 있고, 2~12㎝ 깊이에서 유기물 함량과 Cr, Cu, Zn등의 농도가 급격하게 감소하여 유지되고 있다. 이는 장기적으로 준설물 피복효과가 유지되어 피복층 아래의 퇴적물을 격리하고 있는 것으로 보이며, 준설물질로 피복된 구역의 복원효과가 자연복원 구역보다 상대적으로 유효하며, 지속적으로 유지될 가능성을 나타낸다. We examined the capping effects of dredging materials on the sediment contamination areas due to intensive wastewater treatment sludge dumping activities before 2006 in the Yellow Sea. In the Yellow Sea dumping site. Cr, Cu. and Zn continue to exceed the Threshold Effects Level (TEL) in natural recovery areas, and in areas covered by dredging materials. changes in the concentration of contaminants in surface sediments are considered to be reduced after capping for four years. The annual changes in the vertical profiles of sediments covered with dredged material show that organic matter content and concentrations of Cr. Cu. and Zn are decreased rapidly at a depth of 2 to 12㎝. In the long term, the effect of capping the dredged material is maintained and seems to isolate sediments below the capping layer. The remediation effect of the capping by the dredged material is relatively more valid than that of the natural recovery and indicates the possibility of continuous maintenance.
저용량 Clarithromycin 3 제요법과 Tinidazole 을 포함하는 3 제요법의 Helicobacter pylori 제균 효과
최일주(Il Ju Choi),정현채(Hyun Chae Jung),최규완(Kyoo Wan Choi),김진호(Jin Ho Kim),안득수(Deuk Soo Ahn),양웅석(Ung Suk Yang),유종석(Jong Sun Rew),이상인(Sang In Lee),이종철(Jong Chul Rhee),정인식(In Sik Chung),정준모(Joon Mo Chung),홍 대한소화기학회 2001 대한소화기학회지 Vol.37 No.5
Background/Aims: Proton pump inhibitor-based triple therapies are recommended as the first-line treatment for Helicobacter pylori (H. pylori) eradication. However, the effect of lowering clarithromycin dose and the efficacy of nitroimidazole-containing regimen in metronidazole-resistance prevalent area are uncertain. The aim of this study was to evaluate the efficacy of low-dose clarithromycin triple therapy and tinidazole-containing triple therapy. Methods: This was a randomized multicenter prospective study. A total of 352 patients with duodenal ulcer or non-ulcer dyspepsia patients were randomly divided into 3 groups according to the administered regimen: OAC250 group (omeprazole 20 mg, amoxicillin 1,000 mg, clarithromycin 250 mg), OAC500 group (omeprazole 20 mg, amoxicillin 1,000 mg, clarithromycin 500 mg), and OTC group (omeprazole 20 mg, tinidazole 500 mg, clarithromycin 500 mg). The 3 groups received each regimen twice daily for 7 days. Upper gastrointestinal endoscopy was performed before and 4 weeks after treatment. H. pylori status was determined by the rapid urease test and the 13C urea breath test. Results: The eradication rates in the OAC2SO, OAC500 and OTC group were 76.2%, 65.7% and 64.8% by intention-to-treat analysis (p=0.149) and 92.8%, 87.2% and 84.1% by per-protocol analysis, respectively (p=0.088). Ulcer-healing rates were not significantly different among the three groups and all regimens were well-tolerated. Conclusions: Low-dose clarithromycin triple therapy and tinidazole-containing triple therapy were both effective and safe regimens for H. pylori eradication. (Korean J Gastroenterol 2001;37:336- 344)