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활동성 궤양성 대장염 환자에 있어서 도플러 초음파의 유용성
정수석(Soo Suk Jung),조용균(Yong Kyun Cho),박정식(Jeong Sik Park),김시영(Si Young Kim),김창섭(Chang Seop Kim),손정일(Chung Il Sohn),박창영(Chang Young Park),김병익(Byung Ik Kim),정을순(Eul Soon Jung),박해원(Hae Won Park),전우규(Woo K 대한소화기학회 2002 대한소화기학회지 Vol.39 No.3
Background/Aims : An increase in splanchnic blood flow in both artery and vein has been observed in activeulcerative colitis (UC). Doppler ultrasonography (US) is a non-invasive evaluation method of splanchnic arterialinflow in superior mesenteric artery (SMA). This study was undertaken to assess the usefulness of Doppler Usin detecting changes of the hemodynamic variables in patients with UC. Methods: Twenty-two patients with UC(14, active UC; 8, inactive UC) were studied, and compared with 14 matched healthy subj ects. Flow velocity,resistance index (RI), and pulsatile index (PI) of the SMA were evaluated by Doppler US. Results: Peaksystolic velocity was significantly higher in patients with active UC than in patients with inactive UC and control (178±53 m/sec vs. 117±15 m/ sec, 111±24 m/ sec; p<0.05). The PI of SMA was significantly lower inpatients with active and inactive UC than in control (1.58±0.53, 1.7±0.52 vs. 2.9±0.44; p<0.05). Minimaldiastolic velocity and RI of the SMA were not significantly different among three groups. Conclusions: Peaksystolic velocity of SMA reflects the activity of the disease in patients with UC. Doppler US in patients with UC is an important non-invasive, readily available method to evaluate the activity of the disease and predict itsrecurrence. (Korean J Gastroenterol 2002;39 :192-197)
알코올 및 바이러스성 간경변증에서 세균성 감염 빈도의 비교
박정식(Jeong Sik Park),조용균(Yong Kyun Cho),이은정(Eun Jung Rhee),정수석(Soo Suk Jeong),김시영(Si Young Kim),김창섭(Chang Seop Kim),박창영(Chang Young Park),손정일(Chung Il Sohn),전우규(Woo Kyu Jeon),김병익(Byung Ik Kim),정을순(Eul 대한내과학회 2002 대한내과학회지 Vol.62 No.2
N/A Background: Liver cirrhosis may be considered one of the most common cause of acquired immunodeficiency. Alcohol abuse may be predisposing factor to infections in patients with liver cirrhosis, so we compared the rate of spontaneous bacterial peritonitis (SBP) and other bacterial infections in alcoholic and viral liver cirrhosis. Methods: We studied 188 patients who had been diagnosed with liver cirrhosis from January 1995 to June 2000 and evaluated the frequency of bacterial infections (SBP, pneumonia, urinary track infection, bacteremia, infectious colitis) retrospectively according to cause and degree of cirrhosis. Results: Among 188 patients (alcoholic 76, viral 112), 64 patients (34%) presented with bacterial infection at hospitalization, 33 (43%;33/76) of 64 subjects were alcoholic and 31 (28%;31/112) of 64 subjects were viral liver cirrhosis. The rate of bacterial infections was higher in alcoholic liver cirrhosis than viral cirrhosis (p<0.05). The rate of SBP and other bacterial infections were more frequent in patients of Child-Pugh class C than in those of Child-Pugh class A and B (p<0.01, p<0.05) respectively. Patients of alcoholic liver cirrhosis were more susceptible to bacterial infection than those of viral liver cirrhosis with Child-Pugh class A/B (p<0.05), but no difference was noted in patients of Child-Pugh class C (p>0.05). Conclusion: This results suggest that the rate of bacterial infections are more common in alcoholic than viral liver cirrhosis in relatively early stage and it may be influence the prognosis of liver cirrhosis.(Korean J Med 62:159-164, 2002)