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치과 치료를 위한 외래 정주진정 법에 대한 다기관 후향적 임상연구
정세화,백상현,노현기,강나라,임재중,이병하,전재윤,황경균,심광섭,박창주,Jung, Se-Hwa,Baik, Sang-Hyun,Roh, Hyun-Ki,Kang, Na-Ra,Im, Jae-Jung,Lee, Byung-Ha,Jeon, Jae-Yoon,Hwang, Kyung-Gyun,Shim, Kwang-Sup,Park, Chang-Joo 대한악안면성형재건외과학회 2009 Maxillofacial Plastic Reconstructive Surgery Vol.31 No.5
Purpose : On outpatient facilities, our sedation protocol focuses on the intermittent bolus injections of midazolam intravenously, according to patient's and operator's needs during the dental treatment. This multicenter retrospective study was aimed to prove the efficiency and safety of our sedation protocol. Patients and Methods : In three centers using the same outpatient sedation protocol for dental treatment (Division of Oral and Maxillofacial Surgery/Department of Dentistry in Hanyang University Medical Center, S-plant Dental Hospital. and Grand Oral and Maxillofacial Surgery), total 937 patients had various dental treatments under intravenous conscious sedations with independent patient monitoring from March 2006 to March 2009. By reviewing charts, we analyzed the results of sedation and dental treatment, retrospectively. Results : Our sedation protocol had no severe postoperative complications requiring admission. while showing good compatibility with almost all dental treatments, with acceptable satisfaction of both patients and operators. Conclusion : We assure that our sedation protocol can be used efficiently and safely on routine outpatient basis. We also hope that this study will provide the concrete concepts to common dental practitioners, who desire to perform sedation for dental treatment.
아두이노를 활용한 휴대용 전기자기파 측정기 개발 및 황용방안에 대한 연구
정세화(Se Hwa Jung),명노준(No Jun Myeong) 한국IT마케팅학회 2014 한국IT마케팅학회 학술대회 Vol.2014 No.1
Media which is using electro-magnetic waves rapidly changes our lifestyle and makes our daily lives convenient. But concerns about electro-magnetic waves are being updated since WHO categorised it as a carcinogen(2B). So we aim to know how much electro-magnetic waves are generated and measured from daily electronic devices by developing electro-magnetic waves using Aduino which is open source tool and, to let people be safe by making themselves consistently check effect of electro-magnetic radiation.
Doxorubicin에 의해 활성화된 미세 아교세포의 면역반응으로 인한 신경손상에 Noni가 미치는 영향
정세화 ( Se-hwa Jung ),이성민 ( Seong-min Lee ),하지선 ( Ji-sun Ha ),양승주 ( Seung-ju Yang ),김평환 ( Pyung-hwan Kim ) 대한임상검사과학회 2020 대한임상검사과학회지(KJCLS) Vol.52 No.4
Microglial cells function as major immune cells in the brain, playing an important role in the protection and damage of neurons. BV2 microglia, activated by drug stimulation, secrete inflammatory cytokines by activating the nuclear factor kappa-light-chain-enhancer of the activated B cells pathway and are involved in neuroinflammatory and immune responses. The overactivation of microglia by stimuli can cause neuronal damage, leading to brain disease. Noni, a natural product, reduces the activity of microglia to prevent neuronal damage and is a potential natural medicine because it exerts excellent regeneration and anti-inflammatory effects on damaged cells. In this study, when noni was used to treat BV2 cells stimulated by the anti-cancer drug doxorubicin, it reduced the release of pro-inflammatory cytokines from BV2. On the other hand, neuronal damage is a side effect of doxorubicin. Therefore, the cytokines released from doxorubicin-stimulated BV2 cells treated with noni had a positive effect on the neuronal viability compared to those released from doxorubicin-stimulated BV2 cells not treated with Noni. Thus, Noni increases neuronal viability. These results suggest that noni inhibits the release of cytokines by regulating the nuclear factor kappa-light-chain-enhancer of the activated B cells pathway of BV2, thereby inhibiting neuronal damage. Copyright Ⓒ 2020 The Korean Society for Clinical Laboratory Science. All rights reserved.
정세화(Se-Hwa Jung),정용규(Yong-Gyu Jung) 한국정보과학회 2009 한국정보과학회 학술발표논문집 Vol.36 No.2C
신경망은 인간 뇌의 뉴런들이 상호작용하여, 경험과 학습을 통해 특정 사건으로부터 일반화하고, 패턴을 분류 하는 방식을 이용한 것으로, 금융분야를 비롯 많은 곳에서 성공적 모델이 제시 되어져 왔다. 그러나 이러한 신경망은 학습된 내용을 다룸에 있어 인간이 이해하기 쉽게 설명하기 어려운 면이 많은 것과, 과훈련(overtrained)에 따른 과적합(overfitting) 이 발생하기 쉽다는 문제점을 가지고 있으며, 과적합의 문제와 같은 경우는 은닉 노드의 수에 크게 민감하다는 면을 가지고 있다. 따라서 본 논문은 신경망을 은행고객에 대한 표본 데이터에 적용하여 고객 관리에 대한 모델을 제안 하고자 한다. 신경망의 적용에 있어서 은닉층의 수와 은닉 노드의 수는 출력되는 결과에 대하여 많은 차이를 초래 하기에 실험을 통하여 최적의 은닉 노드를 찾는 모델을 제시하고자 한다.
치과치료를 위한 정주진정법에 사용되는 미다졸람에 대한 역설적 반응 -증례 보고 및 문헌고찰-
전재윤,정세화,이병하,임재중,황경균,심광섭,박창주,Jeon, Jae-Yun,Jung, Se-Hwa,Lee, Byung-Ha,Im, Jae-Jung,Hwang, Kyung-Gyun,Shim, Kwang-Sup,Park, Chang-Joo 대한치과마취과학회 2009 Journal of Dental Anesthesia and Pain Medicine Vol.9 No.2
Midazolam, one of the most common benzodiazepine derivatives, is widely used in intravenous sedation for dental treatment without severe complications. However, paradoxical reactions to midazolam, including patient's unanticipated restlessness, agitation, hostility, and rage, have been frequently reported since the introduction of benzodiazepine. During outpatient intravenous sedation using midazolam for dental treatment, we experienced a paradoxical reaction to midazolam in a 28-year-old female patient. With a thorough review of the literature, the management of this complication and its various etiologies were discussed.
빙정호,전재윤,정세화,황경균,박창주,서광석,김현정,염광원,심광섭,Bing, Jung-Ho,Jeon, Jae-Yoon,Jung, Se-Hwa,Hwang, Kyung-Gyun,Park, Chang-Joo,Seo, Kwang-Suk,Kim, Hyun-Jeong,Yum, Kwang-Won,Shim, Kwang-Sup 대한치과마취과학회 2007 Journal of Dental Anesthesia and Pain Medicine Vol.7 No.2
Background: Dental disabilities mean the poor cooperation for dental treatment because of patient's inherent disability, severe fear and anxiety, and communication problem. Sedation and general anesthesia are usually used for behavioral control in dentally disabled patients. In particular, sedation (conscious and deep) can help them to tolerate the proper dental treatment effectively and safely. Methods: From March 2002 to September 2007, total 35 sedation were carried out in 33 patients (male : female = 20 : 13) with dental disabilities at Seoul National University Dental Hospital and Hanyang University Medical Center. Patients' dental charts and sedation records were retrospectively reviewed. Results: Tooth extraction (19 cases) was the most common dental treatment performed under intravenous sedation (30 cases). Occasionally, inhalation sedation using Sevoflurane 1-2% was adapted (5 cases). Deep sedation (28 cases) was carried out using midazolam 2-3 mg bolus injection and propofol infusion via TCI (4.2 ${\pm}$ 0.9 mg/kg/h), and conscious sedation (7 cases) was carried out using midazolam bolus onlywithout severe complications. The duration of dental treatment was 25.5 ${\pm}$ 12.3 min and that of sedation was 43.2 ${\pm}$ 9.7 min. Conclusion: Sedation for dentally disabledpatients should be selected for effective behavioral control in conjunction with general anesthesia, considering the duration and pain-evoking potentials of dental treatment, the type and severity of patients' disabilities, and the experience of dental anesthesiologists altogether.