http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
기존 치료에 반응하지 않는 진균 각막염에서 전방내 보리코나졸 주입술의 임상 효과
정세형,이효석,조재갑,윤경철,Se Hyeong Jeong,MD,Hyo Seok Lee,MD,Jae Kap Cho,MD,Kyung Chul Yoon,MD,PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.5
Purpose: To evaluate clinical effects of intracameral voriconazole injection in fungal keratitis refractory to conventional therapy. Methods: Thirty-eight eyes of 38 patients with fungal keratitis were included in this study. The patients were divided into 3 groups: 13 patients with intracameral voriconazole injection (50 μg/0.1 ml; group A), 11 patients with intracameral amphotericin B injection (10 μg/0.1 ml; group B), and 14 patients with conventional therapy only (group C). Clinical factors including treatment success rate and time to successful treatment were evaluated. Results: Treatment success was accomplished in 12 eyes in group A (92.3%), 10 eyes in group B (90.9%), and 12 eyes in group C (85.7%). Time to treatment success in group A, B, and C was 36.1 ± 10.4 days (p = 0.04), 34.2 ± 7.8 days (p = 0.03), and 49.5 ± 16.7 days, respectively. Patients who had received intracameral voriconazole injection or amphotericin B showed faster fungal keratitis improvement than patients who received conventional treatment. Time to re-epithelialization and time to disappearance of hypopyon showed a similar clinical course. Conclusions: Intracameral voriconazole injection, which has a similar therapeutic effect as intracameral amphotericin B injection in the management of fungal keratitis, can be helpful in the treatment of intractable fungal keratitis.
전층각막이식술 후 각막감각의 장기 변화 및 이와 관련된 눈물막변수의 분석
정세형,오한진,윤경철,Se Hyeong Jeong,MD,Han Jin Oh,MD,Kyung Chul Yoon,MD,PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.9
Purpose: To evaluate the long-term changes in the corneal sensitivity and to analyze which tear film parameters correlate with corneal sensitivity after penetrating keratoplasty (PKP). Methods: Twenty-eight eyes of 28 patients who underwent PKP were included in the present study. Corneal sensitivity, Schirmer test, tear break-up time, tear clearance rate, and keratoepitheliopathy were evaluated at 1, 3, 6, 12, and 24 months postoperatively. Then, which tear film parameters correlated with corneal sensitivity during the follow-up period were analyzed. Results: Corneal sensitivity was 5.18 ± 3.96 mm at one month postoperatively and increased to 29.64 ± 12.39 mm (p < 0.05) at 24 months postoperatively but was still not in the normal range. Tear break-up time and keratoepitheliopathy improved at postoperative three months and six months, respectively, compared with one month postoperatively, and both measures normalized at 24 months postoperatively. Schirmer test results and tear clearance rate were in the normal range during the follow-up period. Corneal sensitivity was correlated with tear break-up time from three to 24 months postoperative and with tear clearance rate from one month to 24 months postoperative (p < 0.05). Conclusions: Change in corneal sensitivity after penetrating keratoplasty correlates with tear break-up time and tear clearance rate; therefore, tear break-up time and tear clearance rate can be used as parameters for management of dry eye after PKP. J Korean Ophthalmol Soc 2012;53(9):1247-1253
데스메막박리 자동각막내피층판이식술 후 발생한 단순포진바이러스 각막염 1예
정세형,조재갑,윤경철,Se Hyeong Jeong,MD,Jae Kap Cho,MD,Kyung Chul Yoon,MD 대한안과학회 2012 대한안과학회지 Vol.53 No.3
Purpose: To report a case of herpes simplex keratitis after descemet stripping automated endothelial keratoplasty (DSAEK). Case summary: A 66-year-old male underwent DSAEK in his right eye due to bullous keratopathy after cataract surgery. The corneal epithelium which was removed during surgery was healed, but the patient was experiencing pain and decreased visual acuity in his right eye 1 month after surgery. Increasing corneal epithelial defects and corneal edema were observed on slit-lamp examination. Therapeutic soft contact lenses and artificial tears were used for treatment but were not effective, thus amniotic membrane transplantation was performed. Three months after transplantation, the epithelial defect appeared as a geographic ulcer suspecting to be herpes simplex keratitis; therefore, ganciclovir ophthalmic ointment and oral acyclovir were administered. Six months after antiviral therapy, the epithelial lesion of herpes simplex keratitis completely disappeared, leaving only mild corneal opacity. Conclusions: If corneal epithelial defects are persistent after DSAEK in patients even with no past history of herpes simplex keratitis, herpes simplex keratitis should be considered in the differential diagnosis. J Korean Ophthalmol Soc 2012;53(3):473-477
정세형,박정원,박상우,윤경철,허환 대한안과학회 2012 대한안과학회지 Vol.53 No.1
Purpose: To review the recent changes in the clinical features of ocular trauma in pediatric patients younger than 15 years of age. Methods: We performed a retrospective study using clinical records of 147 patients from 1993 to 1998, and those of 175 pediatric patients younger than 15 years old from 2003 to 2007. Results: The most common cause of pediatric ocular trauma in the 2000’s was fist blow (66 patients, 37.7%), while that in the 1990’s was trauma by stick or branch (20 patients, 13.6%) (p < 0.001). The number of patients with perforating ocular trauma decreased to 25 patients (14.3%) in the 2000’s, from 55 patients (37.4%) in the 1990’s (p < 0.001). The number of patients who received surgery due to ocular trauma was 87 (59.2%) in the 1990’s, decreasing to 53 (30.3%) in the 2000’s (p < 0.001). The number of orbital wall reconstructions increased from 6 patients (6.9%) in the 1990’s to 20 patients (37.7%) in the 2000’s, a statistically significant increase (p < 0.001). Conclusions: Perforating ocular trauma decreased in children in the studied age range, but non-perforating injuries caused by fist blow were increased in the years studied. These results indicate that management or establishment of preventive for pediatric violence will be helpful to lower the frequency of pediatric ocular traumas. J Korean Ophthalmol Soc 2012;53(1):145-150
개선된 진화론적 구조최적화에 의한 트러스 구조물의 형태결정
정세형,편해완 한국공간구조학회 2003 한국공간구조학회지 Vol.3 No.3
The purpose of this study is to improve convergence speed of topology optimization procedure using the existing ESO method and to deal with topology decision of the truss structures according to a boundary condition, such as cantilever type. At the existing ESO topology optimization procedure for the truss structures, the adjustment of member sizes according to target stress has been executed by increasing or reducing a very small value from each member size. In this case, it takes too much iteration till convergence. Accordingly, it is practically hard to obtain optimum topology for a large scale structures. For that reason, it is necessary to improve convergence speed of ESO method more effectively. During the topology decision procedure, member sizes are adjusted by calculating approximate solution for member sizes corresponding to the target stress at every step, the new member sizes are adjusted by such method are applied in FEA procedure of next step.
뇌동맥류와 뇌동정맥 기형의 진단에 있어서 회전식 혈관조영술의 유용성
정세형 대한영상의학회 1998 대한영상의학회지 Vol.38 No.1
Purpose: To evaluate the role of rotational angiography in the diagnosis, characterization, and postoperativeassessment of aneurysm, and in the analysis of arteriovenous malformation(AVM). Materials and Methods: Between May1995 and February 1997, 31 patients who had undergone DSA and rotational angiography were retrospectivelyevaluated. Rotational angiographic and lateral DSA images were compared by two radiologists, and in 22 patientswith aneurysmal clipping, location, visibility of the aneurysmal neck, vascular branch anatomy, and projection andshape of the aneurysm were evaluated. The presence or absence of residual aneurysmal neck was evaluated in eightpostoperative patients, and the anatomy of feeder artery and intranidal aneurysm were evaluated in five AVMpatients. Result: Twenty-seven aneurysms were found in 22 of 26 patients in whom DSA had indicated thispossibility. Rotational angiography was superior to conventional DSA in the assessment of neck(67%), vascularbranch anatomy(41%), and projection(22%), location(19%), and shape(15%) of the aneurysm. Rotational angiographyhelped confirm the absence of aneurysm at 11 sites, and was also superior to conventional DSA for confirming theabscence of residual neck in four of eight postoperative patients, and to evaluate feeder artery in four of fiveAVM patients. Conclusion: Rotational angiography is better than conventional DSA for the evaluation of aneurysmand AVM.
불확실 변동특성이 고려된 철골 평면 트러스의 이산화 최적설계
정세형(Jeong Se-Hyung),손수덕(Shon Su-Deok),오영대(Oh Young-Dae),강문명(Kang Moon-Myung) 대한건축학회 2003 大韓建築學會論文集 : 構造系 Vol.19 No.8
This study is proposed to suggest reliability analysis and stochastical discrete optimum design method using stochastic finite element method(SFEM) for plane steel trusses. Usually there are a lot of uncertainties about the error of assumed load, material property, member size and structural analysis in structures. In existing deterministic method, the member design has been accomplished applying safety factor after structural analysis, but it is not enough to consider the uncertainties of structure above mentioned. Thus, in order to consider uncertainties of structure, it is proposed the stochastical analysis method of plane steel trusses using the reliability analysis method, SFEM and advanced first order second moment method(AFSOM). And the optimum method applied in this study is micro-genetic algorithms with stochastical discrete optimum design method in satisfaction of target reliability index.