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      • SCOPUSKCI등재
      • SCOPUSKCI등재

        흉폐부위에 악성소세포종 -증례 보고-

        최명선,정규병,Choi, Myung-Sun,Chung, Kyoo-Byung The Korean Society for Radiation Oncology 1986 Radiation Oncology Journal Vol.4 No.1

        흉폐부위에서 발생하는 악성소세포종양은 1979년 Askin이 보고했고 이를 Askin종양이라고 부른다. Askin종양은 상당히 희귀하며 흉벽에 연조직이나 폐가장자리에서 잘 생기며 특히 젊은 층에 호발한다. 임상적, 병리학적으로 Ewing's sarcoma와 Rhabdomyosarcoma와 상당히 흡사하나 정밀한 전자현미경 관찰시 병리학적으로 별개에 종양으로 간주되었다. Askin종양은 국소재발이 많고 전신으로 잘 터지지 않는 경향이 있으나 생존율은 상당히 나쁜 것으로 되어 있다. 임상적으로나 병리학칙으로 Askin종양에 해당되는 24계 환자를 치료결과와 더불어 보고한다. The malignant small round cell tumor of the thoracopulmonary region was described by Askin in 1979 and called as Askin Tumor. The Askin tumor is a rare, arises from the soft tissues of the chest wall or peripheral lung which is predominantly in younger generation. Clinical and pathologic appearance were very similar to Ewing's sarcoma and rhabdomyosarcoma but when examined it by electron microscopy, there was some different in morphology. The tumor tended to recur locally and did not seem to disseminated widely but the median survival was only 8 months.

      • SCOPUSKCI등재

        Malignant Small Cell Tumor of the Thoracopulmonary Region

        Myung Sun Choi(최명선),Kyoo Byung Chung(정규병) 대한방사선종양학회 1986 Radiation Oncology Journal Vol.4 No.1

        흉폐부위에서 발생하는 악성소세포종양은 1979년 Askin이 보고했고 이를 Askin종양이라고 부른다. Askin종양은 상당히 희귀하며 흉벽에 연조직이나 폐가장자리에서 잘 생기며 특히 젊은 층에 호발한다. 임상적, 병리학적으로 Ewing's sarcoma와 Rhabdomyosarcoma와 상당히 흡사하나 정밀한 전자현미경 관찰시 병리학적으로 별개에 종양으로 간주되었다. Askin종양은 국소재발이 많고 전신으로 잘 터지지 않는 경향이 있으나 생존율은 상당히 나쁜 것으로 되어 있다. 임상적으로나 병리학칙으로 Askin종양에 해당되는 24계 환자를 치료결과와 더불어 보고한다. The malignant small round cell tumor of the thoracopulmonary region was described by Askin in 1979 and called as Askin Tumor. The Askin tumor is a rare, arises from the soft tissues of the chest wall or peripheral lung which is predominantly in younger generation. Clinical and pathologic appearance were very similar to Ewing's sarcoma and rhabdomyosarcoma but when examined it by electron microscopy, there was some different in morphology. The tumor tended to recur locally and did not seem to disseminated widely but the median survival was only 8 months.

      • SCOPUSKCI등재
      • KCI등재후보

        혐색소형 신세포암의 나선식 CT 소견: 병리조직학적 소견 및 예후와의 비교

        조규란,박철민,정환훈,김형래,박범진,이영흔,서보경,차상훈,이창희,정규병,Cho, Kyu-Ran,Park, Cheol-Min,Chung, Hwan-Hoon,Kim, Hyoung-Rae,Park, Bum-Jin,Lee, Young-Hen,Seo, Bo-Kyeong,Cha, Sang-Hoon,Lee, Chang-Hee,Chung, Kyoo-Byung 대한영상의학회 2002 대한영상의학회지 Vol.46 No.1

        목적: 혐색소형 신세포암의 특징적인 나선식 CT 소견을 알아보고 종양의 병리소견, 핵등급, 병기, 그리고 예후와의 연관성을 알아보고자 하였다. 대상과 방법: 병리학적으로 확진된 167예의 신세포암중 11예(6.6%)의 혐색소형 신세포암을 대상으로 나선식 CT와 조직소견을 후향적으로 분석하였다. CT상 종양의 크기, 내부 구조, 감쇠(attenuation), 경계, 정맥과 림프절로의 전이 여부를 관찰하였고 병리소견, Fuhrman의 핵등급, Robson 병기, 그리고 예후와의 연관성에 대해 알아 보았다. 열명의 환자에서 추적 CT로 종양의 재발 유무를 알아 보았는데 추적 기간은 27-80개월(평균 49.6개월)이었다. 결과: CT상 모든 예는 고형이고 신 실질과 경계가 좋으며 크기는 2.5-15 cm(평균 7.7 cm)이었다. 조영증강전 CT상 신 실질과 등음영(n=1)또는 저음영(n=10)이었고 조영증강 초기와 후기에 모두 저음영으로 보였다.3예에서는 내부에 국소적으로 괴사 또는 낭성 변화로 판단되는 저음영 부위가 있었는데 이는 병리조직 소견상 유리화로 확인되었다. 정맥이나 림프절로의 침범 또는 원격 전이를 보인 예는 없었다. 병리조직소견상 낭성 변화는 1예, 출혈이나 괴사는 5예, 완전한 피막화는 3예, 신주위 지방층으로의 파급은 3예에서 보였다. 핵등급은 II(n=6)나 III(n=5)였고 병기는 I(n=8)혹은 II(n=3)였다. 핵등급이 III인 5예중 3예는 병기 I이었고 2예는 병기 II였다. 추적 검사상 모든예에서 종양의 재발은 없었고 모두 생존하고 있다. 결론: 혐색소형 신세포암은 조영증강 전, 조영증강 초기 및 후기 나선식 CT상 신 실질보다 저음영이고 경계가 좋은 고형 종양이며 핵등급이 높은 경우에도 상대적으로 병기가 낮고 예후가 좋다. Purpose: To describe the spiral CT findings of CRCC and to correlate these with the pathologic features, nuclear grading, tumor staging, and prognosis. Materials and Methods: We encountered eleven cases of CRCC among 167 cases of histopathologically proven RCC, retrospectively evaluating the spiral CT findings of CRCC including tumor size, internal texture, attenuation, margin, and the involvement of veins or lymph nodes. In addition, the CT findings were correlated with the pathologic features, Fuhrman's nuclear grade, Robson’s staging, and the prognosis. Between 27 and 80 (mean, 49.6) months later, the follow-up CT scans of tea patients were examined for tumor recurrence. Results: All tumors, which ranged in size from 2.5 to 15 (mean, 7.7) cm, were solid and well demarcated from renal parenchyma. Pre-contrast CT scans showed that their attenuation was equal to (n=1) or slightly lower (n=10) than that of renal parenchyma, and on early and delayed phase post-contrast enhanced scans, attenuation was low in all cases. In three, focal areas in which attenuation was lower than in the rest of the tumor were observed; histopathologically, these represented hyalinization. There was neither venous nor lymph node involvement, and no distant metastasis. Histopathologic examination demonstrated cystic change (n=1), hemorrhage or necrosis (n=5), complete encapsulation (n=3) and perirenal fat infiltration (n=3). Nuclear grading was II (n=6) or III (n=5), and tumor staging was I (n=8) or II (n=3). Among the five cases in which the nuclear grade was III, three were stage I and two were stage II. Follow-up scans showed no evidence of tumor recurrence, and all patients survived. Conclusion: Pre-, early- and late-phase post-contrast enhonced spiral CT scans showed that the attenuation of a CRCC was lower than that of renal parenchyma. Even where the nuclear grade was higher, a well-demarcated soild mass was observed, the tumor stage was lower and the prognosis better.

      • SCOPUSKCI등재
      • 心血管造影術後 尿蛋白値變化에 關한 臨床的 硏究

        鄭圭柄,崔明宣,徐源赫 고려대학교 의과대학 1982 고려대 의대 잡지 Vol.19 No.2

        The contrast medium is widely used in modern diagnostic radiology for angiogrphy, urography, cholangiography, CT scan other many radiological studies. Recently, using iodine contrast media are excellent for the diagnostic aids and relatively harmless to the human organs. But there are a few reports of renal failure following intravascular administration of contrast media, and proteinuria following nephroangiography. We studied the levels of blood urea nitrogen, serum and urine creatinine, and urine protein prior to the angiography, at one hour, 6 hour and 12 hour after angiographic studies, respectively. The study consisted of 15 patients, 9 males and 6 femaes, and the mean age was 43, range from 26 to 57 years. All the patients had no evidence of renal problem prior to the study. The angiographic studies were including 6 cases of abdominal aortography with selective celiac arteriography., 4 cases of left ventriculography, 3 cases of cerebral arteriography and 2 cases of femoral arteriography. The contrast media was diatrizoate meglumine 60%, 76% or iothalamate meglumine 60%, and the mean dose was 1.5㎖/㎏ of body weight. The summerized results were as follow: 1. There was no significant change of blood urea nitrogen or serum creatinine level before and after angiography. 2. The urine protein became two times at one hour after angiography, and 3 times at 6 hour. 3. The urine creatinine was decreased at 6 hour after angiography, but the difference was not significant comparing to the protein elevation. 4. The urine protein, creatinine and protein/creatinine ratio were normalized at 12 hour after angiography.

      • KCI등재
      • 골수염 진단에 있어서 골스캔의 유용성

        전혜정,박정희,신현준,최영칠,이상천,김명규,정규병 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

        Bone scintigraphy using technetium is a simple, safe and accurate method in the diagnosis of osteomyelitis. Bone scan can find the exact site of osteomyelitis and the needle aspiration and surgical drainage. Bone scan is the choice of diagnostic method for determining bone infection in children who are unable to communicate of in those whose signs have been modified by previous inadequate antibiotic therapy. We had the eleven patients whose symptoms are suspicious bone infection taken both technetium bone scan and plain radiographs from March 1996 to April 1997. We analyzed the images of bone scans and plain radiographs retrospectively and studied that how useful the bone scan is. Among eleven patients, the bone scan showed all positive finding of bone infection, but the plain radiographs revealed normal finding in six cases, soft tissue swelling in three cases, bone destruction in one case and periosteal reaction in one case. Conclusively, bone scan is very useful in localization of exact lesion and early detection of osteomyelitis.

      • 늑골병변과 골 스캔: 소견 및 유용성

        전혜정,박정희,신현준,최영칠,이상천,김명규,정규병 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

        We analyzed the image findings of bone scan and plain radiographs of 23 patients. The thirteen patients were traumatic rib fractures. Five patients were metastatic rib tumors. Five patients were rib caries. Differential diagnostic point were discussed by using bone scan images. Although 50 lesions were seen as increased uptake in the bone scan, only 30 lesions were found in the plain radiographs. In metastatic tumors, multiple lesions are scattered over the whole body. In fracture cases, the lesions are located one by one in orders, multiple increased uptake lesions are found in the same rib. In the caries cases, rib lesions were easily found by bone scan rather than plain radiographs. Increased uptake is also noted in the soft tissue abscess pocket adjacent to rib. Bone scan is very useful in the early detection of bone abnormality, even the etiology of bone lesion by analysis of images of bone scan.

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