금은화, 연교, 포공영 혼합물의 항염증 작용에 관한 연구

최강민 ( Kang Min Choi ),전주현 ( Ju Hyun Jeon ),김은석 ( Eun Seok Kim ),성기정 ( Ki Jung Sung ),김영일 ( Young Il Kim ) 대전대학교 한의학연구소 2021 혜화의학회지 Vol.30 No.1

Objective : The purpose of this study is to investigate the inflammatory-control effects of Cheonghyeol-antidote complex(Lonicera japonica Thunberg, Forsythia viridissima Lindley, and Taraxacum platycarpum H. Dahlstedt complex, CHA) in LPS-induced RAW264.7 cell and mouse inflammation models. Method : For in vitro and in vivo experiment, Indicators such as cell viability, mRNA expression level(iNOS, IL-6, IL-1β, COX-2, TNF-a), Inflammatory factor production(NO, IL-6, IL-1β, TNF-a), and protein phosphorylation level(ERK, JNK, p38) were analyzed. For in vivo experiment, Indicators such as mRNA expression level(iNOS, IL-6, IL-1β, COX-2, TNF-a), Inflammatory factor production(IL-6, IL-1β, TNF-a), protein phosphorylation level(ERK, JNK, p38) and immune cell(white blood cell, lymphocyte) were analyzed. Results : 1. In vitro experiment In cell viability of CHA, CHA showed cell viability below 90% at concentrations of 400 μg / ml or more. In mRNA expression level, IL-6 and IL-1β showed a significant decrease at all concentrations except 25 μg / ml concentration, and iNOS, COX-2, and TNF-a showed a significant decrease at all concentrations of CHA compared to the control group. In inflammatory factor production, NO and TNF-a showed a significant decrease at all concentrations except 25 μg / ml concentration of CHA, and IL-1β showed a significant decrease at 100, 200 μg / ml concentration of CHA compared to the control group. IL-6 showed a significant decrease at all concentration of CHA compared to the control group. In protein phosphorylation level, ERK and p38 showed a significant decrease at all concentrations except 25 μg / ml concentration of CHA and JNK showed a significant decrease at all concentrations of CHA compared to control group. 2. In vivo experiment In mRNA expression level, iNOS, COX-2 and TNF-a showed a significant decrease in all administration groups of CHA compared to the control group. In Inflammatory factor production, IL-6, IL-1β and TNF-a showed a significant decrease in all the administration groups of CHA. In protein phosphorylation level, ERK, JNK, and p38 showed a significant decrease in all the administration groups of CHA. In the immune cells, leukocytes and lymphocytes showed a significant decrease in all the administration groups of CHA. Conclusions : This study shows that CHA has antioxidant and inflammatory-control effects on LPS-induced RAW264.7 cells. It is hoped that further research will be conducted on the individual mechanisms of Lonicera japonica Thunberg, Forsythia viridissima Lindley, and Taraxacum platycarpum H. Dahlstedt.

3D-DCT 기반 집적영상 압축 방법의 율-왜곡 최적화를 통한 부호화 효율 향상 방법

전주일(Ju-Il Jeon),강현수(Hyun-Soo Kang) 한국콘텐츠학회 2012 한국콘텐츠학회논문지 Vol.12 No.9

본 논문에서는 집적영상의 압축 방법 중에 하나인 적응적인 블록 모드 선택을 이용한 3D-DCT 기반의 압축 방법에 율-왜곡 최적화 방법을 적용하여 부호화 효율을 개선하는 방법을 제안한다. 적응적인 블록모드 선택을 이용한 3D-DCT 기반의 압축 방법은 영상 특성에 따라 적응적으로 다양한 크기의 3D-DCT 블록을 구성한 후에 3D-DCT를 수행하는 방법이다. 제안 방법은 기존 방법에서 최적 블록 모드를 선택할 때, 율-왜곡 최적화 방법을 적용하여 부호화 효율을 개선하였다. 또한 실험을 통해 집적영상에 적합한 최적의 라그랑지 계수를 제시하였다. 제안 방법은 기존 방법과 비교해 약 5%의 비트량 절감 효과를 가진다. In this paper, we propose a rate-distortion optimization method to improve the coding efficiency of the conventional 3D-DCT based compression method using adaptive block mode selection for integral images. In the conventional 3D-DCT based compression method, 3D-DCT blocks of variable block sizes are adaptively selected depending on the characteristics of integral images, and then 3D-DCT is performed. The proposed method applies a rate-distortion optimization to determine the optimal block mode. In addition, we suggest the optimal Lagrangian parameter for integral images. Experimental results show that the proposed method gives bit-rate reduction of about 5%.

공학교육인증프로그램 운영 효과 증진을 위한 CQI 시스템에 관한 연구

전주현(Ju-Hyun Jeon),김남일(Nam-il Kim),한중근(Jung-Geun HAN) 한국정보과학회 2013 한국정보과학회 학술발표논문집 Vol.2013 No.6

흰쥐의 신맥(申脈)($BL_{62}$)에 시술한 저주파 전침자극의 항산화 효과에 대한 실험적 연구

전주현,김영일,이현,Jeon, Ju-Hyun,Kim, Young-Il,Lee, Hyun 대한침구의학회 2007 대한침구의학회지 Vol.24 No.4

Objectives : The purpose of this study is to investigate the anti-oxidative effect of electroacupuncture at Shinmaek($BL_{62}$) in rats. Methods : In order to cause oxidative stress, AAPH was administered to the abdominal cavity of rats, after we stimulated $BL_{62}$ of the rat by electroacupuncture. Blood test and anti-oxidative test(LDL-cholesterol, GOT, GPT SOD, GSH, catalase, NO, MDA) were performed at the end of treatment. Results: 1. SOD, glutathione, catalase activity were significantly increased in the $BL_{62}-EA$ group compared with the holder group. 2. NO density was significantly decreased in the $BL_{62}-EA$ group compared with the holder group. 3. Glutathione was significantly increased in the $BL_{62}-EA$ group compared with the sham-EA group. Conclusion : These results suggest that electroacupuncture at $BL_{62}$ has an anti-oxidant effect in human.

적응적 3D-DCT를 이용한 집적영상 압축 방법

전주일(Ju-Il Jeon),장세훈(Se-Hoon Jang),강현수(Hyun-Soo Kang) 대한전자공학회 2010 대한전자공학회 학술대회 Vol.2010 No.6

In this paper, we propose an efficient compression method of the integral images. The integral imaging is a well-known technique to represent and record three-dimensional images. The proposed method is a compression method efficient to integral images using 3D-DCT technique. The 3D-DCT blocks adaptive to the characteristics of integral images are constructed and then 3D-DCTs for the 3D blocks are performed. Experimental results show that the proposed method can give bit-rate reduction of about 10% .

H.264/AVC 인트라 예측모드 부호화 분석

전주일(Ju-Il Jeon),김재민(Jae-Min Kim),박종화(Jong-Hwa Park),강현수(Hyun-Soo Kang) 대한전자공학회 2007 대한전자공학회 학술대회 Vol.2007 No.11

In this paper, we empirically analyze a new prediction method for intra prediction mode in H.264/AVC. The intra prediction mode of a 4×4 luma block is predictively coded using the intra prediction modes of its neighboring blocks, upper and left 4×4 blocks. The most probable mode is chosen as the prediction value of the intra prediction mode. If the most probable mode is equal to the intra prediction mode of the luma block, a single flag bit is set to ‘1’ and followed by nothing. Otherwise, a single flag bit is set to ‘0’ and followed by 3 bits to signal the intra prediction mode. It means that it is important to choose the most probable mode in saving the bits to signal the mode. Therefore, we introduce a new method to choose the most probable mode, in which an additive neighboring block as well as upper and left blocks is considered to do it. We empirically evaluate and analyze its performance comparing to the standard method.

영상측위시스템을 위한 사용자 참여형 측위 DB 자동갱신방법 설계

전주일(Jeon Ju Il),지명인(Ji Myung In),김주영(Kim Ju Young),박상준(Park Sang Joon),조영수(Cho Young Soo) 한국통신학회 2015 한국통신학회 학술대회논문집 Vol.2015 No.06

이명(耳鳴)의 한의학적 치료에 대한 임상적 고찰

전주현,최은희,김영일,Jeon, Ju-Hyun,Choi, Eun-Hee,Kim, Young-Il 대한침구의학회 2008 대한침구의학회지 Vol.25 No.3

Background and Objectives : This case report aims to determine the effect of acupuncture and herbal medicine as a treatment for tinnitus. Subjects and Methods : 11 patients with tinnitus were treated by acupuncture combined with herbal medicine. Patients were evaluated with verbal numerical rating scale scores for loudness, annoyance, and awareness of tinnitus before and after treatment. Results : 9 patients reported reduction of loudness, annoyance, and awareness of tinnitus after treatment. Among them, complete suppression of the tinnitus was obtained in 1 case. 2 patients reported no improvement. Conclusions : This case study presents clinical possibility of acupuncture and herbal medicine for the treatment of tinnitus.

3D 입체 영상을 위한 집적 영상 압축 방법

전주일(Jeon Ju-Il),이강산(Lee Kang-San),강현수(Kang Hyun-Soo) 한국방송·미디어공학회 2009 한국방송공학회 학술발표대회 논문집 Vol.2009 No.11

본 논문에서는 집적 영상을 효율적으로 압축하는 방법을 제안한다. 렌즈 어레이를 이용하여 획득되는 집적 영상은 3차원 영상을 기록하고 표현하는 기술 중에 하나이다. 3차원 영상의 복원은 각 요소영상의 해상도에 의해 많은 영향을 받음에 따라 효율적인 집적영상 압축은 매우 중요하다고 할 수 있다. 제안된 방법은 3D 이산 코사인 변환(3D-DCT)를 기반으로 하고 있다. 3D-DCT는 렌즈 어레이로 촬영된 인접 영상들 간의 교차 상관도를 이용하여 영상간 중복성을 줄여 압축 효율을 향상시킬 수 있는 방법이다. 제안방법은 인접 영상들 간의 교차 상관도를 고려하여, 동일 위치의 픽셀들로 8×8 DCT블록을 재구성하여 3D-DCT를 수행한다. 제안 방법은 기존의 JPEG이나 기존의 3D-DCT를 이용한 방법과 비교해 더 좋은 성능을 보여준다.

적응적인 블록 모드를 이용한 집적 영상의 효율적인 압축 방법

전주일(Ju-Il Jeon),강현수(Hyun-Soo Kang) 大韓電子工學會 2010 電子工學會論文誌-SP (Signal processing) Vol.47 No.6

본 논문에서는 집적 영상을 효율적으로 압축하는 방법을 제안한다. 집적 영상은 3차원 영상을 기록하고 표현하는 대표적인 기술이다. 제안된 방법은 3D 이산 코사인 변환(3D-DCT)를 기반으로 하고 있다. 집적 영상 부호화에서 3D-DCT는 인접요소 영상간의 중복성을 줄이는 효율적인 압축 방법으로 알려져 있다. 제안방법은 3D-DCT에 기반 하면서 적응적인 블록 모드를 이용한 효과적인 집적영상 압축 방법으로서, 영상의 특성에 따라 적응적으로 3D-DCT 블록을 구성함으로써 가변블록 크기 3D-DCT 블록을 생성하고, 이 가변블록 크기의 3D 블록에 대해 3D-DCT를 수행한다. 실험 결과를 보면 제안방법이 기존 방법과 비교해서 더욱 높은 압축 효율을 보여주었다. 특히 영상이 복잡하여 많은 비트량이 발생하는 영상이 오버헤드 비트의 영향이 적기 때문에 더 좋은 압축 효율을 보여주었다. In this paper, we propose an efficient compression method of the integral images. The integral imaging is a well-known technique to represent and record three-dimensional images. The proposed method is based on three dimensional discrete cosine transform (3D-DCT). The 3D-DCT techniques for the integral images have been reported as an efficient coding method for the integral images which reduces the redundancies between adjacent elemental images. The proposed method is a compression method efficient to integral images using adaptive block mode(ABM), based on the 3D-DCT technique. In the ABM, 3D-DCT blocks adaptive to the characteristics of integral images are constructed, which produces variable block size 3D-DCT blocks, and then 3D-DCTs for the 3D blocks are performed. Experimental results show that the proposed method gives significant improvement in coding efficiency. Especially, at the high bit-rates, the proposed method is more excellent since the overhead incurred by the proposed method take less part of the total bits.