견관절 조영술의 임상적 및 방사선학적 고찰

장희열 대한영상의학회 1984 대한영상의학회지 Vol.20 No.3

The authors analyzed 23 cases of shoulder arthrography performed at Busan National University Hospital and Inje Medical College Paik Hospital for about 2.5 years from March 1981 to September 1983, both clinically and radiologically. The results obtained were as follows: 1. Of the 23 cases, 20 cases (87.0%) were male and 3 cases (13.0%) were female, and the most prevalent age group was second decade. 2. Right shoulder arthrogaphy was performed in 16 cases (96.6%), and left in 7 cades (30.4%) 3. the number of cases which had had certain history of trauma was 13 (56.5%) and remainder of 10 cases (43,5%) had no history of trauma. 4. Frequent symptoms and signs were pain in shoulder region in 16 cases (69.6%) were normal, and 7 cases (30.4%) were abnormal. Those abnormal cases were consisted of 2 cases(8.7%) of adhesive capsulits, 2 cases (8.7%) of chronic shoulder dislocation, 1 case (4.3%) of rotator cuff tear, 1 case (4.3%) of loose bodies in joint cavity, and 1 case (4.3%) of rupture of biceps tendon sheath. 7. among routine views of shoulder arthrography of normal cases, the external rotation view revealed axillary recess & biceps tendon more distinctly, and the internal rotation the contour & thickness of the medial segment of the contrast-coated humeral articular cartilage were well demonstrated in erect views, with air-fluid levels in axillary recess, biceps tendon sheath & subscapular bursa. 8. The 2 cases of adhesive capsulitis revealed small joint space, obliteration of the axillary recess & subscapular bursa, and failure to fill the bicipital sheath.

Flutter를 이용한 TTS화자의 다중 음색 지원

장관우(Gwanwoo Jang),최진영(Jinyoung Choi),김용주(Yongju Kim),김윤정(Yunjung Kim),최희열(Heeyoul Choi) 한국정보과학회 2020 한국정보과학회 학술발표논문집 Vol.2020 No.7

콜레스테롤 함유 식이 랫드에서 감귤껍질추출물 BNs-3 및 BNs-7의 항비만 효과

채희열(Hee-Youl Chai),신지순(Ji-Soon Sin),권운(Woon Kwon),최은경(Ehn-Kyoung Choi),조영민(Young Min Cho),장호송(Hu-Song Zhang),황석연(Seock-Yeon Hwang),복성해(Song-Hae Bok),김윤배(Yun-Bae Kim),강종구(Jong-Koo Kang) 한국독성학회 2003 Toxicological Research Vol.19 No.3

The protective effects of BNs-3 and BNs-7, extracts of citrous orange peel, on the obesity induced by ad libitum feeding a cholesterol-containing diet to rats were investigated. The animals<br/> were fed on the diet including cholesterol (0.5%) with or without the citrous orange peel extracts BNs-3 (5%) and/or BNs-7 (0.1%) for 8 weeks. The ad libitum feeding a diet containing cholesterol to<br/> rats from 6 weeks of age increased the body weight gain compared with that of rats fed on a normal diet. Such an increase in body weights was markedly attenuated by the addition of BNs-3 or BNs-7 to the diet. Especially, a combinational feeding on BNs-3 and BNs-7 significantly reduced the body weight gain below that of normal diet-fed animals. Interestingly, the weights of abdominal adipose tissues surrounding epididymides were greatly reduced by the citrous orange peel extracts, in parallel with the decrease in body weights. In addition, blood concentrations of lipids including cholesterol were also lowered by the combinational treatment with BNs-3 and BNs-7. Taken together, it is suggested that the obesity and overweight produced by unrestricted overfeeding on diet with cholesterol may be partially due to the accumulation of abdominal adipose tissues, around the epididymides in rats, and that citrous orange peel extracts might exert antiobese activities by reducing the adipose tissues as well as blood lipid concentrations.

성인 정신분열병 환자에서 손톱주름 총 시도(叢 視度) (Nailfold Plexus Visibility)와 임상 변인과의 관계

강대엽,장희열,강성숙,Kang, Dae-Yeob,Chang, Hi-Yeoul,Kang, Sung-Suk 대한생물정신의학회 1999 생물정신의학 Vol.6 No.1

Objectives : There have been several evidences that the central nervous system defect is one of the etiologic factors in schizophrenia and high nailfold plexus visibility can reflect these defects indirectly. These are particularly related to the negative symptoms of schizophrenia. In this study, we examined the relationship between nailfold plexus visibility and various clinical variables in schizophrenia. Methods : Forty patients(20 males, 20 females) satisfying the DSM-lV criteria for schizophrenia and forty normal controls(20 males, 20 females) were measured for Plexus Visualization Score (PVS) by using capillary microscopic examination. We used Positive and Negative Syndrome Scale(PANSS), Ulmann-Giovannoni Process-Reactive Questi-onnaire(PRQ), Phillips Premorbid Adjustment Scale(PAS), Continuous Performance Test, and Backward Masking for psychopathology and clinical variables. Results : There was no significant relationship between schizophrenic subjects and normal controls in PVS. PVS was correlated with PANSS positively except negative symptom subscore. PVS was correlated with PRQ score negatively, and with PAS score positively. Conclusions : This study shows high PVS are associated with more severe psychotic symptoms and with clinical variables, such as disease process and premorbid adjustment, in some schizophrenics. 본 연구에서 저자들은 성인 정신분열병환자에서 손톱주름 총 시도와 정신분열병의 발생연령, 정신 병리, 진행성, 병전 기능, 인지기능과의 관련성을 알아보고자 DSM-IV의 진단기준에 맞는 정신분열병 환자 40명과 대조군 40명을 선택하여 연구한 결과 다음과 같은 결과를 보여주었다. 첫째, 정신분열병 대상군($6.2{\pm}5.9$)과 정상 대조군($5.2{\pm}6.0$) 간의 총 시도 점수(PVS)에서 통계적으로 유의한 차이가 없었고 (t=-0.67, p=0.252), 고도의 PVS 비율에서도 두 군간의 통계적인 차이가 없었다(${\chi}^2$=2.90, p=0.088). 둘째, PVS 많을수록 음성 증상을 제외한 PANSS의 모든 증상군에서 통계적으로 유의한 상관 관계를 보여주었다. 셋째, 발병연령이 빠를수록 PVS가 높았다(r=-0.291, p=0.034). 넷째, 병전적응이 안 좋을수록 PVS가 높았다(r=0.265, p=0.049). 다섯째, 정신분열병의 경과가 진행성일수록 신체미세기형이 많았다(r=-0.272, p=0.045). 여섯째, PVS와 CPT 정답률과는 역 상관관계(r=-0.375, p=0.009)를, CPT 개입 오류와는 상관관계(r=0.293, p=0.041)를 보여주었다. 본 연구의 소견에서, 손톱주름 총 시도가 정신분열병의 음성 증상과 관계된 일부 소견들에서만 연관이 있다는 것을 시사하고 있지만 이 연구는 적어도 어떤 형태의 정신분열병 환자들에 있어서 손톱주름 총 시도는 안 좋은 병전 적응력, 진행성 정신분열병과 같은 부분적으로 음성증상과 관련이 있는 임상 변인들 사이에 연관성을 보여 주었고, 이러한 소견은 정신분열병의 어떤 아형의 원인에 있어서 기질적인 영향이 있을 수 있다는 것을 암시한다.

Cephalosporin계 항생제 IDC7181에 대한 항원성시험

신지순(Ji Soon Sin),장호송(Hu-Song Zhang),최은경(Ehn-Kyoung Choi),권운(Woon Kwon),채희열(Hee-Youl Chai),조영민(Young Min Cho),김윤배(Yun-Bae Kim),강종구(Jong-Koo Kang) 한국독성학회 2003 Toxicological Research Vol.19 No.4

Antigenic potential of a novel cephalosporin, IDC7181 was examined a active systemic anaphylaxis (ASA) and passive cutaneous anaphylaxis (PCA) test, in guinea pig and mouse-rat models, respectively. In ASA test, IDC7181 induced the signs of restlessness in a few animals immunized with a high dose (100 mg/kg) of IDC7181 alone or in combination with Freund's complete adjuvant (FCA). In PCA test, only one of ten sera from the animals immunized with a high dose (100 mg/kg) of IDC7181 in the absence or presence of FCA showed positive reaction. The positive reaction,<br/> induced by IDC7181, which may be due to β-lactam ring, in ASA and PCA tests were negligible in comparison with those of traditional cephalosporins. Taken together, it is suggested that IDC7181 do<br/> not cause immunological problems in clinical dosage.

상엽의 4주 반복투여독성 평가

황석연(Seock-Yeon Hwang),권운(Woon Kwon),채희열(Hee-Youl Chai),조영민(Young-Min Cho),이남진(Nam Jin Lee),류재면(Jae Myun Ryu),신지순(Ji Soon Sin),김태명(Tae Myung Kim),조정희(Jung-Hee Cho),장자영(Ja Young Jang),박정휘(Jung-Hui Park) 한국실험동물학회 2004 Laboratory Animal Research Vol.20 No.3

The purpose of this study was to confirm the safety of the water extract of Mori folium single (MFS) or mixed (MFM) compound. Male Sprague-Dawley rats were orally administered with MFS or MFM at dose levels of 0.5, 1.0 or 2.0 g/㎏/day for 4 weeks. As results, there were no significant differences in the body weight gain between vehicle control and MFS or MFM-treated rats. Also, significant changes in daily feed intake and water consumption were not observed during the experimental period. In hematological analysis, there was a trend of decrease in prothrombin time, in contrast to a slight delay in activated partial thromboplastin time following MFS or MFM treatment. And white blood cells (WBC), especially lymphocytes, somewhat increased. In serum biochemical analysis, aspartate transaminase, alanine transaminase and alkaline phosphatase, related to hepatic injuries, decreased. Also, renal and pancreatic toxicity parameters such as blood urea nitrogen, creatinine and amylase decreased by MFS or MFM treatment. Interestingly, serum globulin fraction in total proteins increased, suggestive of an immunopotentiation effect, in accordance with the increase in WBC. There were no significant changes in organ weights, and no gross and histopathological lesions were observed. Taken all together, it is proposed that repeated treatment with the extract of Mori folium or its mixture, available in oriental clinics, may not exert considerable adverse effects, and that rather protect against tissue injuries and enhance immune functions.

Text-To-Speech를 위한 Transfer Learning에 화자 성별이 미치는 영향

김윤정(Yunjung Kim),김용주(Yongju Kim),최진영(Jinyoung Choi),장관우(Gwanwoo Jang),최희열(Heeyoul Choi) 한국정보과학회 2020 한국정보과학회 학술발표논문집 Vol.2020 No.7