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불임증(不姙症) 환자(患者)의 통계적(統計的) 고찰(考察);서울대학교병원(大學校病院) 불임상담실(不姙相談室) 1872 예(例)의 분석(分析)
장윤석,이진용,문신용,김정구,최승헌,임용택,Chang, Y.S.,Lee, J.Y.,Moon, S.Y.,Kim, J.K.,Choi, S.H.,Lim, Y.T. 대한생식의학회 1985 Clinical and Experimental Reproductive Medicine Vol.12 No.1
This study was presented of the 1,872 cases of infertile couples who visited and examined at the sterility clinic of Department of Obstetrics & Gynecology, Seoul National University Hospital from Sept., 1980 to Dec., 1983. Age, duration of infertility, past medical history, and other general factors were analyzed, and the factors responsible for infertility were classified and discussed. Mode of treatment, outcome of pregnancy, pregnancy rate responsible for each factor were also presented. The results were as follows: 1) The infertility was primary in 1,128, or 60.3% and secondary in 744, or 39.7%. 2) The age between 26 and 30 years of age comprised about one half of the total patients. 3) The duration of infertility between 1 and 4 years comprised about three quarters of the total patients, and the mean duration was 3.8 years. 4) The most common medical history in primary infertility was tuberculous disease, and that in secondary infertility was history of previous laparotomy. 5) About two thirds of antecedent pregnancies were abortion. 6) The major etiologic factor of infertility were male factor in 12.3%, tubal factor in 38.8%, ovulatory failure in 25.4%, uterine factor in 8.8%, cervical factor in 5.2%, peritoneal factor in 9.5%, and no demonstrable cause in 11.3%. 7) The types of male factor were azoospermia in 61.6%, oligospermia in 25.8%, low motility in 11.6%, and other abnormality in 1.0%. 8) The types of ovulatory failure were ovarian failure in 7.4%, hypothalamo-pituitary failure in 8.1 %, hypothalamo-pituitary dysfunction (including Polycystic ovarian syndrome) in 30.2%, and hyperprolactinemia in 22.4%. 9) The types of uterine factor were endometrial tuberculosis in 27.5%, uterine synechia in 33.8%, uterine anomaly in 19.7%, myoma and polyp in 9.1 %, and luteal phase defect in 9.9%. 10) The types of peritoneal factor were pelvic adhesion in 80.9% and endometriosis in 19.6%. 11) Surgeries were done in 408 patients, and they were salpingolysis, lysis of extraadnexal adhesion, salpingostomy, fimbrioplasty, ovarian wedge resection for polycystic ovarian disease, tubo-tubal anastomosis, and tubo-uterine implantation in orders. 12) 243 pregnancies were achieved during the infertility work-up, of which livebirth was 46.5%, ectopic pregnancy was 7.4%, spontaneous abortion was 7.8%, and on-going pregnancy or lost to follow-up was 36.2%. 13) Pregnancy rates in various factors were male factor in 18.7%, ovulatory factor in 31.7%, tubal factor in 24.2%, uterine factor in 34.6%, cervical factor in 19.0%, peritoneal factor in 29.0%, combined factors in 10.5%, and unexplained infertility in 37.1%. Pregnancy rate in whole patients was 25.2%.
정상월경주기및 클로미펜을 이용한 배란유도 월경주기에서의 난포성장에 관한 연구
장윤석,이진용,문신용,김정구,임용택,한광수,Chang, Y.S.,Lee, J.Y.,Moon, S.Y.,Kim, J.K.,Lim, Y.T.,Han, K.S. 대한생식의학회 1986 Clinical and Experimental Reproductive Medicine Vol.13 No.1
Follicle monitoring in the normal and clomiphene·stimulated cycles were analyzed in the Seoul IVF and ET (In vitro fertilization and embryo transfer) program. Ovarian follicular diameters were measured by the real·time sector scanner and plasma estradiol levels were assayed by radioimmunoassay methods during periovulatory period. The maximum follicular sizes of the clomiphene-stimulated and normal cycles were 21.1+-3.4mm and 19.2+-0.8mm, respectively. The peak levels of plasma estradiol in the clomiphene-stimulated and normal cycles were 10538+-553.6ng/ml and 298.3+-39.6pg/ml, respectively. Daily growth rate of the follicular diameters of the clomiphene-stimulated and normal cycles were 2.1mm and 1.9mm, respectively. Mean follicular number of the clomiphene-simulated and normal cycles were 2.28+-1.12 and 1.12+-0.21, respectively. There was a good statistical correlation between the mean follicular diameters and the plasma estradiol levels in the normal ovulatory and c1omiphene-stimulated ovulatory menstrual cycles (p<0.05). Our data revealad that the mean follicular diameter and the plasma estradiol level prior to HCG administration in IVF and program should reach at the level of 17.8+-3.0mm and 949.4+-487.1 pg/ml, respectively.
마우스 난자(卵子)의 체외수정(體外受精)에 관(關)한 연구(硏究)
임용택,최승헌,김정구,문신용,이진용,장윤석,Lim, Y.T.,Choi, S.H.,Kim, J.G.,Moon, S.Y.,Lee, J.Y.,Chang, Y.S. 대한생식의학회 1984 Clinical and Experimental Reproductive Medicine Vol.11 No.2
The success of human in vitro fertilization (IVF) & embryo transfer (ET) has focused attention on the culture conditions that can provide optimal development of the preimplantation embryo. Studies of in vitro fertilization using mouse have direct implications to human IVF, since similar conditions are used for both species. Mouse IVF as a quality control system for human IVF & ET was studied since Feb., 1984. The results were as follows: 1. Egg retrieval following superovulation in IeR mice was l5.1${\pm}$5.3 eggs ovulated/mouse (Mean${\pm}$ S.D.) 2. In vitro cleavage rate was 61.7% (1146 eggs cleaved/l858 eggs inseminated) and % blastocyst was 42.6%. 3. In comparison with two media of Ham's F-10 and m-KRB, in vitro cleavage rate were 40.9%/63.l% and %blastocyst were 44.3%/61.2% (P<0.05). 4. It was concluded that mouse IVF system has a valuable place in human IVF & ET as a quality-control system and in human reproductive physiology as a research model.
차세대 지능형 공항 시스템 개발 -실시간 화물지원 자원 추적 관리 연구-
장윤석 ( Y. S. Chang ),정상효 ( S. H. Jung ),류재신 ( J. S. Ryu ) 한국항공경영학회 2008 한국항공경영학회 춘계학술대회 Vol.2008 No.-
정부는 항공 분야의 R&D 투자를 지속적으로 확대하여 왔으나 이의 투자성과는 미미한 것으로 평가되어 사업의 선택과 집중을 위해 ``건설교통 R&D 혁신로드맵``을 수립하여 이를 근간으로 하는 연구개발 전략을 추진했다. ``21C 동북아 항공 중심국 및 G-10 수준의 항공선진국 진입``을 목표로 미래 지향적인 항공기술을 육성 발전하기 위한 ``항공 선진화`` 사업을 추진 중이며, 이와 같은 국가적 목표의 달성을 위해서는 공항의 효율화 및 지능화에 대한 연구와 개발이 반드시 필요한 실정이다. 본 연구에서 개발되는 핵심 및 기반기술은 장래 공항의 운영환경 변화에 대응하여 여객 및 화물처리 능력 강화, 공항시설의 안전성 확보 및 운영효율을 증진할 수 있는 혁신 기술을 개발함으로써, 국내 공항 및 항공산업의 경쟁력을 강화하고 항공분야의 지속적 성장과 발전을 도모할 수 있는 실용화 기술을 개발하는 사업이다.
다공형상이 존재하는 가압기의 피로수명평가 및 응력분류선 유효성 분석
최신범(S.B. Choi),박영재(Y.J. Park),장윤석(Y.S. Chang),최재붕(J.B. Choi),김영진(Y.J. Kim),이진호(J.H. Lee),정해동(H.D. Jeong),설광원(K.W. Seul) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.11
The present research deals with stress analyses and fatigue life evaluation of a new complex pressurizer that includes perforated parts due to various piping and subcomponents. At first, preliminary two- and three-dimensional finite element analyses were carried out to assess the feasibility of an effective elastic modulus. Then, the appropriateness of stress classification line prescribed in ASME Sec. Ⅲ & Ⅷ and WRC Bulletin 429 as non-mandatory appendices was reviewed. Finally, after categorizing stress components, the stress intensities and cumulative usage factors at critical points of pressurizer were calculated through main analyses and compared with corresponding allowable design criteria in ASME code.
IT 모듈의 자유 낙하 모사를 위한 병렬처리시스템의 적용
박영재(Y. J. Park),이준성(J. S. Lee),고한옥(H. O. Ko),장윤석(Y. S. Chang),최재붕(J. B. Choi),김영진(Y. J. Kim) 한국정밀공학회 2006 한국정밀공학회 학술발표대회 논문집 Vol.2006 No.5월
Recently, the flat display modules such as plasma or TFT-LCD employ thin crystallized panels which are normally weak to high level transient mechanical energy inputs. As a result, anti-shock performance is one of the most important design specifications for TFT-LCD modules. However, most of large display module designs are generated based on engineers own experiences. Also, a large-scale analysis to evaluate complex material and structural behaviors is one of interesting topic in diverse engineering and scientific fields. The utilization of massively parallel processors has also been a recent trend of high performance computing. The objective of this paper is to introduce a parallel process system which consists of general purpose finite element analysis solver as well as parallelized PC cluster. The parallel processing system is constructed using thirty-two processing elements and the finite element program is developed by adopting hierarchical domain decomposition method. In order to verify the efficiency of the established system, an impact analysis on thin and complex sub-parts of flat display modules is performed. The evaluation results showed a good agreement with the corresponding reference solutions, and thus, the parallel process system seems to be a useful tool for the complex structural analysis such as IT related products.