밸런스 마스터 시스템을 이용한 골프선수의 균형 능력 평가

임길병 ( Kil Byong Lim ),이홍재 ( Hong Jae Lee ),주성주 ( Sung Joo Joo ),임성식 ( Sung Shick Lim ),채지원 ( Ji Won Chae ),박종율 ( Jong Yul Park ),박범영 ( Bum Yong Park ) 대한스포츠의학회 2006 대한스포츠의학회지 Vol.24 No.2

급성 신부전의 임상적 고찰

김재필(Jae Pill Kim),최남수(Nam Su Choi),임성식(Sung Shick Lim),이상억(Sang Eog Lee),홍화정(Hwa Jung Hong),홍성표(Seong Pyo Hong),이태원(Tae Won Lee),임천규(Chun Gyoo Ihm),김명재(Myung Jae Kim),박원도(Won Do Park),김영훈(Yeong Hoon K 대한내과학회 1997 대한내과학회지 Vol.52 No.5

N/A Objective: Acute Renal Failure is a clinical syndrome characterized by a sudden decrease in renal function which was previously normal. Despite advances in medical care, prognosis in ARF is variable according to the influence of demographic factors, severity of ARF, nature of disease causing ARF, coexisting disease, treatments applied, and complications. We studied the recent changes of clinical feature of ARF. Mcthods: We studied retrospectively 245 patients with ARF who had been hospitalized at Kyung Hee University Hospital between February 1988 and March 1993. Results: 1) Male to female sex ratio was 1.8:1, and the incidence was high in above fifth decade (67.8%). 2) Acute renal failure was classified, according to clinical background, into medical group 79.6% (195 cases) and surgical group 20.4% (50 cases), and oliguric group 40.8% (100 cases) and non-oliguric group 59.2% (145 cases). 3) Acute renal failure due to medical causes included ARF by hemorrhagic fever with renal syndrome (25.6%), drugs and chemicals (17.9%), sepsis (17.4%) and systemic infection (7.7%) etc. ARF due to surgical causes included ARF by multiple trauma (34%), various surgical procedures (30%), surgical sepsis (14%), burn (12%) etc. 4) During admission, the expired patients had more severe biochemical and clinical characteristics including high BUN and serum potassium (p<0.01), lower serum albumin (p<0,01) than those of survivor. 5) Infections as the cause of ARF were 107 cases (43.7%), which included hemorrhagic fever with renal syndrome 50 cases, sepsis 31 cases, urinary tract infection 7 cases and respiratory tract infection 6 cases etc. The most common infecting organism was Hantavizus (50.5%). There was a greater number of gram-negative organisms than gram-positive organisms (34.1% vs 9.9%). 6) The overall mortality rate in patients with ARF was 31.4Fo. The presumptive causes of death were underlying disease (59.7%) such as sepsis, acute poisoning, cardiogenic and hypovolemic shock, and respiratory failure (14.3%), hyperkalemia (9.1%), pulmonary edeme (6.5%), and metabolic aidosis (2.6%) in order of frequency. 7) The highest mortality rate was 42.6% in patients above 50 years old. Mortality rate in patients with ARF due to surgical causes (52.0%) was significantly high than that of medical causes (26.2%) (p<0.05). Among the expired patients, oliguric group was 72.7%. In conclusion, there have been major trends in the clinical features of acute renal failure in this study. Especially, significant increase in the number of elderly patients, non-oliguric patients, and medical causes such as hemarrhagic fever with renal syndrome or sepsis were observed. Survival rate significantly decreased with increasing age, in acute renal failure by surgical causes, in oligurie patients, and in the presence of complicating factors such as sepsis or shock.

선종성 용종성 대장증후군의 병전 진단

한민수(Min Soo Han),김효종(Hyo Jong Kim),김현우(Hyun Woo Kim),임성식(Sung Shick Lim),동석호(Seok Ho Dong),김배영(Bae Young Kim),이정일(Joung Il Lee),장영운(Young Woon Chang),이기형(Kee Hyung Lee),장린(Rin Chang) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.2

N/A Background/Aims: APC is inheritable in an autosomal dominant manner and includes both familia) adenomatous polyposis(FAP) and Gardners syndrome(GS). For the presyptomatic diagnosis of APC, several DNA markers on Sq for linkage analysis are now available. A]so, a PCR-based screening method for mutation analysis is available. To evaulate the usefulness of two different presymptomatic diagnostic tests for APC, we performed linkage and mutation analyses, respectively, on both FAP and GS families. Methods: Genomic DNA was extracted from the peripheral lymphocytes from 8 members of affected fami]ies with APC and 5 members with GS. Five micrograms of each DNA was digested with restriction enzyme Msp I, and Southern blotting and hybridization using the probe EF 5.44 were performed. Using PCR with [a- PJ dCTP incorporated for labelling, DNA fragments were amplified by both the DSS82 and tbe DSS346 locus respectively, and identified by ethidium bromide staining after agarose gel electrophoresis. Products of the PCR were loaded on 10% denaturing(8M urea) polyacrylamide gels in TAE buffer, and the reactions visualized by autography. For the detection of germ-line mutations, two different segments of the APC gene were arnplified by the PCR and analyzed by PAGE. Results: All the polymorphic markers, except CA repeat marker YN5.64 in GS family, are not informative in both FAP and GS fami]ies. Although CA repeat marker YN5.64 is informative in GS family, presymptomatic diagnosis can not be made with certainty because this one is an index family with spontaneous mutation. Using the two systems for the detection of re]atively common germ-line mutations, presymptomatic diagnosis can be made only in GS family. Conclusions: Linkage analysis and systems for the detection of germ-line mutations using PCR, although useful in some situations, could benefit a minority of kindreds with adenomatous polyposis coli. (Korean J Gastroenterol 1996; 28:185 - 197)

급성 및 만성 간질환에서 혈청 Intercelluar Adhesion Molecule - 1 측정의 의의

김병호,김효종,임성식,장린,이정일,동석호 대한간학회 1996 Clinical and Molecular Hepatology(대한간학회지) Vol.2 No.1

Baekground/Aims:Recent studies, have examined the expression of adhesion molecules in liver inflammation, and the existence of soluble ICAM 1 in serum could be proved by ELISA. We maeasured s-ICAM 1 in patients with acute and ehronic liver disease to see the level of s-ICAM 1 can reflect degree of necroinflammation or progress of disease. Method:Serum levels of soluble forms of intercellular adhesion molecule 1(sIGAM 1) in 78 patients with acute and chronic liver disease including acute hepatitis B, CAH, C.'PH, post-necrotic and alcoholic liver cirrhosis, hepatoceliular carcinoma, toxic hepatitis were measured by enzyme-linked immunosorbent assays. Results.① ICAM 1 serum levels in acute and chronic liver disease including acute hepatitis B(709.6+ 321.7 ng/L, p$lt;0.001), C:AH(582.2±312.4 ng/L, p$lt;0.001), CPH(357,8±135.0 ngL, p$lt;0.044), postnecrotic liver cimhosis(716.2± 348.0 ng/L, p$lt;0.0001), alcoholic liver cirrhosis(763.3± 48l.5 ng/L, p$lt;0.009). Hepatocellular carcinoma(728.2±329.0 ng/L, p$lt;0.002), toxic hepatitis(817.3±324.4 ng/l, p$lt;0.0001) were signiticantly higher than that of healthy controLs(234.5+ 67.5 ng/L). ② In comparison with CPH we found significantly increased ICAM- 1 serum levels in CAH.(p=0.027) A significant correlation was found between the ICAM-1 serum level and the histologically graded inflammatory activity in CAH. ③No correlation was found be1ween the ICAM l serum level aml the Child- Pugh classification in liver cirrhosis. ④In comparison with chronic hepatitis we found signitcantly increased 1CAM 1 serum levels in liver cirrhosis(p = 0.001) , and in hepatocellular carcinoma(p = 0.0001), Conclusion:Soluble ICAM I serum level correlated well with ongoing necroinflammatory activity in acute and chronic hepatitis and also slCAM 1 can reflect disease severity in various chronic 1iver disease groups.

내시경적 역행성 췌담도 조영술로 진단한 Fascioliasis 1예

김영준,김병호,김효종,임성식,장린,동석호,이원욱,장영운,이정일 대한소화기내시경학회 1997 Clinical Endoscopy Vol.17 No.1

Fascioliasis is a zoonotic disease caused by Fasciola hepatica, a liver fluke, for which human acts as an accidental host. Fascioliasis, while common in some tropical countries, is rare in Korea. Endoscopie retrograde cholangiopancreatography(ERCP) has been described in only a very few cases as a useful technique for the diagnosis of fascioliasis. We report a case of fascioliasis diagnosed by ERCP, after endoscopic sphinchterotomy adult worms were removed by Dormia basket.