젊은 성인에서 능동 움직임을 결합한 근막감압치료 적용과 정적 적용이 관절가동범위, 근력, 기능적 움직임에 미치는 영향

이지현 ( Jee-Hyun Lee ),김태현 ( Tae-Hyeon Kim ),강시윤 ( Si-Yun Kang ),금도건 ( Do-Gun Kum ),이성연 ( Sung-Yeon Lee ),도광선 ( Kwang-Sun Do ),김창숙 ( Chang-Sook Kim ),배주한 ( Ju-Han Bae ),박준혁 ( Jun-Hyuck Park ),김재은 ( Jae- 대한통합의학회 2021 대한통합의학회지 Vol.9 No.3

Purpose : Myofascial decompression is frequently mentioned as a method applied to cupping. The purpose of this study is to evaluate and compare active range of motion (AROM), muscle strength, and functional movement by applying myofascial decompression to the hamstrings. Methods : This study evaluated AROM, muscle strength, and functional movement by applying active movement myofascial decompression and static myofascial decompression to the dominant leg, respectively, in a crossover design conducted with normal adults (n=21) in their average 20s enrolled at G University in G city, Gyeongsangbuk-do. Active movement myofascial decompression was implemented for five minutes at a rate of 100 bpm to make the beats in flexion and extension respectively. Static myofascial decompression was only performed for five minutes while at rest. All of these interventions were performed at a cupping depth of two ㎜. After a one-week washout period, static was applied again to compare the same dependent variables. Results : Regarding AROM and muscle strength, both groups showed significant differences in the before and after results (p<.05). However, in the Functional Reach Aspect and Single Leg Hop test, the active movement myofascial decompression group showed better results. There was no statistical difference between the Active movement myofascial decompression group and Static myofascial decompression group in any dependent variable (p<.05). Conclusion : As a result of this experiment, both active movement myofascial decompression and static myofascial decompression had a positive effect on dependent variable. Therefore this study is meaningful in that it is easier and simpler to see the effect on flexibility, muscle strength, and functional movement just by implementing movement myofascial decompression.

폭약 및 폭탄 제조시 발생하는 시클로나이트의 작업자 노출수준 평가

정지연 ( Jee Yeon Jeong ),이지현 ( Jee Hyeon Lee ),김은영 ( Eun Young Kim ),이승훈 ( Seung Hoon Lee ) 한국산업위생학회 2011 한국산업보건학회지 Vol.21 No.1

Cyclonite is a white powder and is very explosive. It can cause seizures (a problem of the nervous system) in human and animals when large amounts are inhaled or eaten. Research papers for workers exposure assesment of the cyclonite are very a few in the world. A field study was conducted at explosive compounds and bomb manufacturing companies to evaluate workers exposure to cyclonite. The airborne average concentration of cyclonite in explosive compounds manufacturing company was 4.10 ㎍/㎥(range: ND - 59.92 ㎍/ ㎥), and that of cyclonite in bomb manufacturing company was 31.49 ㎍/㎥(range: ND - 291.41 ㎍/㎥). Package process and assembly process in both companies were considered the high potential of exposure to cyclonite. Even though all airborne concentrations of cyclonite were lower than occupational exposure standard (MOEL: 500 ㎍/㎥), exposure to cyclonite can also occur through dermal contact during manufacture, handling, and clean-up of cyclonite. So control measures for protecting skin absorption of cyclonite were needed for preventing adverse health effect by cyclonite exposure.

사용자 여정 시각화 서비스의 UX 디자인 개선에 관한 연구 -뷰저블 애널리틱스를 중심으로 -

정지현(Jee hyeon Jung),김서연(Seo yeon Kim),박민희(Min hee Park),이지현(Ji hyun Lee) 한국HCI학회 2022 한국HCI학회 학술대회 Vol.2022 No.2

고객의 니즈와 행동 패턴의 정교한 분석이 점점 더 중요해지고, 데이터 기반 UX 디자인이 보편화됨에 따라 다양한 분석 방식이 개발되었다. 하지만 사용자 여정 분석 방법의 고도화를 위해 분석 기능, 시각화 및 사용성 향상을 탐구하는 연구는 미비한 실정이다. 따라서 본 연구는 대표 퍼널 분석 서비스를 분석하여 서비스 경험 향상을 위한 개선 이슈를 도출하였다. 또한, 뷰저블 애널리틱스(Beusable Analytics)를 연구 대상으로 선정하여 전문가 평가를 진행하였다. 다수의 전문가가 언급한 문제점과 그에 따른 UX 디자인 개선안을 도출하였다. 이를 바탕으로 효율적인 데이터 탐색 및 분석을 위한 UI 개선 시나리오를 제안하였다.

조직병리학적 분류에 따른 침윤성 유관상피암의 임상양상

조백현(Baik-Hyeon Jo),허민희(Min Hee Hur),이해경(Hae Kyung Lee),강성수(Sung Soo Kang),이성공(Sung Kong Lee),전이경(Yi Kyeong Chun),김의정(Yee Jung Kim),김혜선(Hye Sun Kim),홍성란(Sung Ran Hong),김희숙(Hy Sook Kim),이지현(Jee Hyun Lee 대한외과학회 2003 Annals of Surgical Treatment and Research(ASRT) Vol.64 No.6

Multicenter retrospective analysis of patients with chronic lymphocytic leukemia in Korea

Jun Ho Yi,이경원,이지현,Kwai Han Yoo,Chul Won Jung,Dae Sik Kim,Jeong-Ok Lee,Hyeon Seok Eom,Ja Min Byun,Youngil Koh,Sung Soo Yoon,Jin Seok Kim,Jee Hyun Kong,Ho-Young Yhim,Deok Hwan Yang,Dok Hyun Yoon,Do Hyou 대한혈액학회 2021 Blood Research Vol.56 No.4

Background Chronic lymphocytic leukemia (CLL) is the most common type of adult leukemia in Western countries but is rare in the East Asian countries. Due to its rarity and the lack of feasible novel agents and laboratory prognostic tools, there are limited data on the clinical outcomes of this disease in Asia. To clarify the current treatment status, we performed a multicenter retrospective analysis of patients with CLL in Korea. Methods The medical records of 192 eligible patients between 2008 and 2019 were reviewed for clinical characteristics, treatment courses, and outcomes. The first-line treatment regimens of the patients included in this analysis were as follows: fludarabine/cyclophosphamide/ rituximab (FCR) (N=117, 52.7%), obinutuzumab plus chlorambucil (GC) (N=30, 13.5%), and chlorambucil monotherapy (N=24, 10.8%). Results The median progression-free survival (PFS) was 55.6 months, and the average 2-year PFS rate was 80.3%. PFS was not significantly different between the patients receiving FCR and those receiving GC; however, chlorambucil treatment was associated with significantly inferior PFS (P <0.001). The median overall survival was 136.3 months, and the average 5- and 10-year OS rates were 82.0% and 57.4%, respectively. Conclusion This is one of the largest studies involving Korean patients with CLL. Although the patients had been treated with less favored treatment regimens, the outcomes were not different from those reported in Western studies.

식품첨가물의 리스크 커뮤니케이션 촉진을 위한 소비자단체의 인식조사

소윤지 ( Yun Ji So ),김선아 ( Sun A Kim ),이지현 ( Jee Hyeon Lee ),박은영 ( Eun Young Park ),김희정 ( Hee Jung Kim ),김지선 ( Ji Sun Kim ),김정원 ( Jeong Weon Kim ) 한국식품조리과학회(구 한국조리과학회) 2013 한국식품조리과학회지 Vol.29 No.2

본 연구는 식품안전에 관심이 높은 소비자단체를 대상으로 설문조사를 실시하여 식품첨가물에 대한 인지도 분석과 함께 리스크 커뮤니케이션 촉진 가능성을 알아보았다. 응답자 111명의 설문지를 분석한 결과, 가공식품을 구입할 때에는 ‘안전성(91.0%)’을 가장 고려하며, ‘식품첨가물 24.3%(27명)’과 ‘환경오염물질 23.4%(26명)’이 식품의 안전을 가장 위협한다고 생각하였다. 식품첨가물에 대한 이해도는 활동 기간이 길수록 높게 나타났고(p<0.01), 응답자 모두는 식품첨가물이 위험하다고 생각하였고 식품첨가물을 섭취하는 양이 많다고 응답하였다. ‘식품첨가물에 관해 가장 알고 싶은 정보’는 ‘안전성 80.8%(84명)’이 대부분을 차지하였다. 식약청의 ‘식품첨가물’ 안전성 평가 연구를 알고 있다고 답한 30.6%(33명) 중 72.7%(24명)가 식품첨가물에 대한 연구가 충분히 이루어지지 않고 있다고 하였고, 추가 연구와 관련해서는 다중섭취와 지속적이고 다각적인 접근이 필요하다고 답하였다. 또한 식품첨 가물에 대한 교육 및 홍보 사업이 적절히 이루어지고 있다고 생각하는가에 대해 ‘그렇지 않다 75.0%(24명)’, ‘전혀 그렇지 않다 15.6(5명)’로 충분하지 않다고 생각하였다. 소비자단체 구성원들이 정보를 얻는 경로는 ‘교육, 강연’, ‘인터넷’, ‘국내 기타 단체’, ‘TV’ 순이고 가장 바람직하다고 생각하는 교육 및 정보 제공방식은 TV(4.65점)로 나타났다. 위 결과, 소비자단체는 식품첨가물을 식품안전을 위협하는 물질로 인식하고 있었고, 정부의 식품첨가물 안전 관리에 대해 일반 소비자들에 비해 매우 낮은 신뢰도를 보이고 있었다. 또한 소비자 대상 교육홍보도 불충분하다고 인식하고 있어, 소비자들의 인식을 주도하는 이들의 식품첨가물에 대한 인식과 정보요구 분석에 따라 지속적인 정보전달 노력을 기울이는 것이 식품첨가물에 대한 리스크 커뮤니케이션 촉진 방안이 될 것이다. Consumer organizations usually lead the opinions of the consumers. This study was performed to investigate the perceptions and information needs of consumer organizations on food additives for the promotion of risk communication. A survey was conducted for 4 weeks in March 2012 by using a self-administered questionnaire consisting of 32 questions. Total 111 responses were collected for analysis. ``Safety (91.0%)`` was the most important factor influencing the purchase of processed food, and both ``food additives (24.3%)`` and ``environmental pollution (23.4%)`` were considered as main risk factors. The longer the career of the members had, the higher negative perceptions on food additives (p<0.01). About 70% of the respondents who had known KFDA`s researches on evaluating safety of food additives answered that researches were not enough to make sure the safety. Although lectures and other domestic organization were the main channels for getting information, ``TV`` was considered as the most suitable way for it. ``Poor risk communication (32.4%)`` was pointed out as the serious problem of government``s food safety policy. Based on these results, consumer organizations`` low level of trust on government should be overcome by continuous supply of information what they need to facilitate risk communication on food additives.

유방 관상피내암의 유방 보존술 후 방사선 치료의 성적과 예후 인자 분석

김경주(Kyoung Ju Kim),허승재(Seung Jae Huh),박원(Won Park),양정현(jeong Hyeon Yang),남석진(Seog Jin Nam),김정한(Jeong Han Kim),이성공(Sung Kong Lee),이지현(Jee Hyun Lee),강성수(Sung Soo Kim),이정은(Jeong Eun Lee),강민규(Min Kyu Kang 대한방사선종양학회 2004 Radiation Oncology Journal Vol.22 No.1

목적: 유방 관상피내암 환자들의 유방 보존술 및 방사선 치료 후 생존율과 국소 재발률, 재발 양상 및 국소 재발에 영향을 준 인자들을 분석하고, 적절한 치료법을 결정하고자 하였다. 대상 및 방법: 1995년 6월부터 2001년 12월까지 유방 관상피내암으로 유방 보존술 후 방사선 치료를 받았던 96명의 환자를 대상으로 후향적 분석을 시행하였다. 수술은 국소 절제 또는 광범위 절제가 시행되었고, 일부에서 액와림프절 곽청술이 시행되었다. 방사선 치료는 전 유방에서 50.4 Gy/ 28회를 조사하였고, 절단면에 종양이 있거나 절단면에서 종양이 가까웠을 경우 (≤2mm) 일부에서 종양이 있었던 부위에 10~14 Gy를 추가 조사하였다. 전체 환자의 중앙 추적 관찰기간은 43개월(12~102개월)이었다. 결과: 5년 국소 무병생존율 생존율은 각각 91%, 100%였다. 국소 재발은 6명(6.3%)에서 발생하였고, 이 중 침윤성 유방암으로 재발한 환자는 1명이었다. 수술에서 재발까지의 기간은 1명을 제외하고는 모두 2년 이상이었다. 주위림프절 재발이나 원격전이는 없었다. 재발한 환자 중 5명은 유방전절제술 후 무병생존 중이고, 1명은 구제 치료예정이다. 국소 재발에 영향을 준 인자들에 대해 문석했을 때 , 연령, 절단면 상태, comedo type, 핵분화도 모두 국소 재발에 영향을 주지 않는 것으로 나타났다. 수술 범위에 따라서도 국소 재발에 차이를 보이지 않았고(p=0.30), 절단면이 종양에서 가까웠던 경우 초기 종양 부위에 추가 조사도 국소 재발에 영향을 주지 않았다.(p=1.0) 결론: 유방 관상피내암의 치료로 유방 보존술 및 방사선 치료 시행 후 높은 국소 제어율과 생존율을 얻을 수 있었다. 종양이 절단면을 침범하지 않는 한 절단면과 종양과의 거리와 추가 방사선 조사는 국소 재발에 영향을 주지 않는 것으로 나타났으나 향후 더 많은 환자로 장기적인 추적관찰이 필요할 것으로 생각된다. Purpose: To evaluate the survival rate, local failure rate and patterns of failure, and analyze the prognostic factors affecting local relapse of ductal carcinoma in situ treated with breast conserving surgery and radiotherapy Materials and Methods: From June 1995 to December 2001, 96 patients with ductal arcinoma in situ treated with breast conserving surgery and radiotherapy were etrospectively analyzed. The operations were either local or wide excision in all patients, with an axillary lymph node dissection performed in some patients. Radiation dose to the whole breast was 50.4 Gy, over 5 weeks, with 1.8 Gy daily fractions, with additional doses (10 14 Gy) administered to the primary tumor bed in some patients with close ( 2 mm) or positive resection margin. The median follow-up period was 43 months (range 12 102 months). Results: The 5-year local relapse free survival and overall survival rates were 91 and 100% respectively. Local relapse occurred in 6 patients (6.3%). Of the 6 recurrences, one was invasive ductal cell carcinoma. With the exception of one, all patients recurred 2 years after surgery. There was no regional recurrence or distant metastasis. Five patients with local recurrence were salvaged with total mastectomy, and are alive with no evidence of disease. One patient with recurrent invasive ductal cell carcinoma will receive salvage treatment. On analysis of the prognostic factors affecting local relapse, none of the factors among the age, status of resection margin, comedo type and nuclear grade affected local relapse. Operation extent also did not affect local control (p=0.30). In the patients with close resection margin, boost irradiation to the primary tumor bed did not affect local control (p=1.0). Conclusions: The survival rate and local control of the patients with ductal carcinoma in situ treated with breast conserving surgery and radiotherapy were excellent. Close resection margin and boost irradiation to the primary tumor bed did not affect local relapse, but further follow-up with much more patients is needed.