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      • SCOPUSSCIEKCI등재

        척수 수질내에 재발한 신경장관성 낭종 - 증례보고 -

        이종주,나영신,강신광,노성우,임승철,Rhee, Jong Joo,Ra, Young Shin,Khang, Shin Kwang,Roh, Sung Woo,Rhim, Seung Chul 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.12

        Neurenteric cysts are developmental cysts derived from embryonic endodermal layers. Fewer than 100 have been reported in which there were no associated bone or soft-tissue malformations and only six among those cases showed intramedullary location in the literatures. The authors report a 16-year-old young man with a thoracic intramedullary neurenteric cyst which presented with symptoms of axillary pain and paraparesis. The magnetic resonance imaging showed intramedullary mass extended from level of T3 to T7. There was no associated bone or soft-tissue anomaly. This cyst was partially excised and marupialized into subarachnoid space. The pathological findings were compatible with neurenteric cyst. Nine months later, the cyst recurred and at second operation, cyst wall was removed completely.

      • SCOPUSSCIEKCI등재

        성인에서 천막상부, 두개엽에 위치한 원발성 교모세포종의 치료에서 종양 절제의 역할

        이종주,안재성,전상룡,김정훈,나영신,김창진,이정교,권병덕,Rhee, Jong Joo,Ahn, Jae Sung,Jeon, Sang Ryong,Kim, Jeong Hoon,Ra, Young Shin,Kim, Chang Jin,Lee, Jung Kyo,Kwun, Byung Duk 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.2

        Objective : The therapeutic impact of tumor resection in glioblastomas is poorly defined and still questionable. Therefore, we conducted the current study to verify the role of tumor resection in the treatment of these highly malignant tumors. Methods : A retrospective study was performed(1990-1999) to compare the treatment results of surgical resection plus radiotherapy(130 patients) with those of stereotactic biopsy plus radiotherapy(19 patients) in glioblastomas. Only adult patients with supratentorial, de novo glioblastoma located in one lobe were included. Survival time/rate was analysed with Kaplan-Meier method, and prognostic variables were obtained from the univariate log-rank test and the multivariate Cox's proportional hazards model. Results : The resection group and the biopsy group did not differ in terms of age, gender, duration of symptoms, presenting symptoms, tumor location, tumor side, tumor size, and the frequency of midline shift. Patients in the biopsy group more often were found to have worse preoperative Karnofsky performance status(KPS)(p=0.001). On univariate analysis, age, KPS, and tumor side were associated with survival(p=0.0053, 0.0001, and 0.0331 respectively). Median survival time and 1-year survival rate were also statistically improved by tumor resection ; resection group - 13 months and 61.2%, and biopsy group - 8 months and 19.7%, respectively(p=0.0001). In patients with midline shift of the tumor, resection was highly effective comparing to biopsy(p=0.0001), but in patients without midline shift, external beam radiation alone was as effective as tumor resection(p=0.0605). Other prognostic variables did not affect survival. On multivariate analysis after variable selection, survival was independently associated with KPS(p=0.001), but not the surgical resection(p=0.2837). Even in biopsy group with midline shift of the tumor, survival rate was not different from that seen after tumor resection(p=0.3505). Conclusions : Radiotherapy alone was as effective as tumor resection plus radiotherapy in patients without midline shift of the tumor. Although there was not statistically significant, tumor resection looked like effective in patients with midline shift. For supratentorial, lobar glioblastoma patients without mass effect of the tumor, biopsy with radiotherapy is one of rational treatment strategies. We consider that tumor resection should be performed in patients with pretreatment midline shift.

      • 전두부 두개골을 침범한 염증성 근섬유모세포종 -증례보고-

        김태호 ( Tae Ho Kim ),최우진 ( Woo Jin Choe ),이승준 ( Seung Jun Lee ),이종주 ( Jong Joo Rhee ),이혜경 ( Hye Kyung Lee ),이채혁 ( Chae Heuck Lee ),김명수 ( Myoung Soo Kim ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2006 대한뇌종양학회지 Vol.5 No.1

        Inflammatory myofibroblastic tumor(IMT) includes a diverse group of lesions characterized by inflammatory cell infiltration and variable fibrotic responses, which mimic neoplastic lesions. IMTs of the head and neck occur most commonly in the orbits, and their occurrence in the skull is rare. To our knowledge, only eight cases of IMTs of the skull(excluding cases in the eye and maxillary sinus) have been reported in Korea. We report a case of IMT involving the frontal bone. A 43-year-old man presented with right frontal pain. A right frontal scalp mass had been removed at another hospital one month ago, but the pain persisted. Brain computed tomography showed a suspected sclerotic lesion near the right coronal suture, with an enhancing epidural mass. A lesion of the frontal bone was removed by craniectomy. The cortical bone appeared pinkish-brown color. Dura mater adherent to the bone showed an inflammatory reaction and thickening and it was removed. Duroplasty and cranioplasty were performed. The pathology test indicated IMT. IMT must be distinguished from other infectious, granulomatous, and neoplastic lesions. It requires an aggressive approach including surgical intervention, with resection of all the bone and dura mater involved. We describe the diagnosis and treatment of skull IMT.

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