가미오령산(加味五?散)이 Streptozotocin으로 유발된 흰쥐의 당뇨병성(糖尿病性) 신증(腎症)에 미치는 영향

이연경,강석봉,Lee, Yeon-Kyeong,Kang, Seok-Bong 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.4

Objectives : The object of this study was to observe the effects of Gamioryung-san (GOS), which consists of 22 types of herbs, on streptozotocin (STZ)-induced diabetic nephropathy rats. Methods : Three different dosages of GOS were orally administered once a day for 28 days from 3 weeks after STZ treatment. Six groups, each of 8 rats per group were used. Changes on the body weights, blood glucose levels, serum BUN and creatinine levels, urine volumes, and UAER were observed with changes on the kidney malondialdehyde contents and glutathione, dismutase and catalase contents. In addition, histopathology of kidney, pancreas, thymus and spleen were observed. The results were compared with antioxidant silymarin 100 mg/kg, of which the effects on STZ -induced diabetes and related complications are already confirmed. Results : As a result of treatment of GOS 800, 400 or 200 mg/kg for 28 days, STZ-induced decreases of body weights, hyperglycemia, atrophic changes of pancreatic islets with decreases of insulin-immunoreactive cells and decreases of glucagon -immunoreactive cells were inhibited dose-dependently. Increases in kidney weight, serum BUN and creatinine levels, urine volumes, UAER, vasodilated atrophic glomerulus and abnormal tubules were inhibited dose-dependently. Also increases of kidney MDA contents and decreases of GSH contents, SOD and CAT activities, decreases of thymus and spleen weights, and atrophic changes at histopathological observation were also inhibited. The effects of GOS 400 mg/kg showed similar effects to silymarin 100 mg/kg. Conclusions : These results suggest that 400 mg/kg of GOS retarded the STZ-induced diabetic nephropathies as similarly to silymarin 100 mg/kg, through modulations of oxidative stress and immune systems.

대분청음(大分淸飮)이 Cisplatin으로 유발(誘發) 된 흰쥐의 급성신부전(急性腎不全)에 미치는 영향(影響)

이연경,윤경민,장수영,강석봉,Lee, Yeon-Keong,Yoon, Kyeong-Min,Jang, Su-Yeong,Kang, Seok-Bong 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.4

Purpose : This study was to observe the nephroprotective effects of the traditional prescription, Daebuncheong-eum (DBCE). DBCE has generally been used for treating various renal diseases, including renal failure. Methods : Three different dosages of DBCE extract were orally administered once a day for 28 days. At the 23rd day after DBCE extract treatment, cisplatin was also treated. Then, 5 days after cisplatin treatment, all rats (6 groups of 8 rats each) were sacrificed. Changes on the body weight, kidney weight, serum BUN and creatinine levels were observed, along with changes to the kidney MDA and GSH contents. The results were compared with captopril 100mg/kg, from which the effects on cisplatin-induced acute renal failures have already been confirmed. Results : Cisplatin induced ARF are induced by oxidative stress and related lipid peroxidation in the present study. However, these ARFs and inhibition of antioxidant effects induced by cisplatin were dose-dependently reduced by treatment of all three different dosages of DBCE extracts. Conclusion : This study suggests that DBCE extracts show favorable effects on cisplatin-induced rat ARF.

당뇨병 및 소갈(消渴)의 최신 연구 동향 -2003년에서 2007년까지 한의학술논문을 중심으로-

이연경,최규호,신현철,강석봉,Lee, Yeon-Kyeong,Choi, Geu-Ho,Shin, Hyun-Cheol,Kang, Seok-Bong 대한한의학방제학회 2007 大韓韓醫學方劑學會誌 Vol.15 No.2

At this moment, because there're lots of necessity to have an attention on diabetus mellitus (DM), in this article searched over all the Korean oriental medical academic journals about DM from 2003 to 2007, Method: Through data base system that Daegu Haany University affiliated information center & Korean Studies Information Center manage, selected 60 articles worthy to look up that are searched by the keyword 'DM' & '消渴'. Result and Conclusion: 5 articles of observing 'DM' & '消渴' itself academically, 29 articles of experimental study, 8 articles of clinical research study and 18 articles of case report. For experimental study, mostly it were concerning type II DM modeled rat medicated herb and its effect, so there were only a few type I experimental study. For observing articles, generally the causes, pathology, treatments, acupuncture methods and medication et al., variable studies were done. In clinical research, diverse categories were subject, which is to prove the efficacy of medication, acupuncture, physical therapy and diet supplements. And in case reports, focused not only on improvement in blood sugar level but also its complications.

기능성 정보 전달 방법 및 소비자 태도에 따른 건강기능식품 광고 효과 분석

이연경,김지연,권오란,황인경,Lee, Yeonkyung,Kim, Ji Yeon,Kwon, Oran,Hwang, In-Kyeong 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.6

본 연구에서는 소비자 중심적인 건강기능식품 기능성 전달방법을 도출하기 위하여 이미지, 원료 및 기능성에 대한 설명, 기능성을 설명하는 도표, 특허 정보, 권위자의 설명 등 다양한 전달 방법들이 소비자의 광고 평가에 미치는 영향을 분석하였다. 또한 소비자들이 이미 가지고 있었던 건강기능식품에 대한 인식들이 광고 평가에 미치는 영향에 대하여 살펴 보았다. 이미 수행된 정성조사(Focus group interview)에서는 실제 사용되던 건강기능식품 광고 50여건을 소비자에게 제시하고, 기능성과 관련하여 소비자의 광고 인식에 미치는 방법들을 찾아내었다. 이렇게 찾은 방법들에 대하여 보다 넓은 범위에서 검증하기 위하여, 이를 바탕으로 6가지의 광고안들을 개발하여 정량 조사를 수행하였다. 6가지 광고안은 각각 정인지 이미지+원료에 대한 설명+기능성을 설명하는 도표, 정인지 이미지+원료에 대한 설명, 정인지 이미지, 오인지 이미지, 오인지 이미지+특허 정보, 오인지 이미지+권위자의 설명을 반영하여 제작되었다. 정량 조사의 대상은 서울 및 수도권 거주자 30~60대 총 300명이었으며, 대인면접법으로 한 사람당 4가지 광고안을 평가하도록 하여 광고안 당 200개의 평가 결과가 나올 수 있도록 하였다. 광고에 대한 평가는 광고 위계 효과 모형에서 제시되는 인지-감정-행동 세 가지 요소가 모두 반영될 수 있도록 '광고가 시선을 끄는가', '광고가 얼마나 이해하기 쉽다고 생각하는가', '제품 기능에 대한 정보가 충분한가', '광고의 메시지에 공감이 가는가', '광고를 통해 제품의 효능/효과를 얼마나 신뢰하는가', '광고를 본 후 구입하고 싶은 생각이 드는가'의 6가지 항목을 질문하였다. 또한 광고에 대한 평가와 함께 소비자들이 건강기능식품에 대하여 가지고 있는 태도를 '건강하기 위해서는 건강기능식품을 꼭 섭취해야 한다고 생각한다', '건강기능식품의 효능/효과에 대해 신뢰한다', '건강기능식품을 구입하기 전에 많은 정보를 수집한 후 구입한다', '평소 건강기능식품 광고들을 관심있게 본다', '건강기능식품 광고에서 전달하는 효능/효과에 대해 신뢰한다' 이렇게 5가지 문항을 통하여 조사하였다. 건강기능식품에 대한 소비자의 태도를 t-검정 및 일원분산분석을 이용하여 분석한 결과, 성별에 따른 차이로서 '광고관심도'에 대해서는 유의적인 차이를 보이지 않았으나, '섭취필수도', '효과신뢰도', '구입 전 정보수집도' 및 '광고내용신뢰도'에 대해서는 여성이 남성보다 유의하게 긍정적인 태도를 취하고 있는 것으로 나타났으며, 연령에 따른 분석 결과로서는 모든 항목에 대하여 40대와 50대 연령층이 30대와 비교하여 보다 긍정적인 태도를 취하고 있음을 알 수 있었다. 제시된 6가지 광고에 대하여 광고 효과를 분산분석한 결과, 단순히 이미지만을 제시한 광고안들에 비하여 원료와 기능성에 대한 정보가 함께 제시된 광고안들의 효과가 유의적으로 높게 평가되어 즉, 원료 및 기능성에 대한 설명, 그래프 형태의 시험 결과 제시, 특허, 권위자의 설명은 인지, 정서, 행동 모든 측면에서 광고 효과를 높일 수 있는 것으로 확인되었다. 하지만 소비자들은 오인지 이미지에 대하여 인지하지 못하여 이에 따른 광고 평가의 영향은 없는 것으로 나타났다. 다른 변수들과의 상호작용을 살펴보기 위하여 이원분산분석을 수행한 결과, 이러한 경향은 성별, 연령과 서로 상호작용을 가지지 않았으며, 성별과 연령 The purpose of this study was to find efficient and customized tools for delivering the benefit of health functional foods (HFFs). Delivery tools which could influence the impact of advertising were images, explanations of ingredients, diagrams of health benefit, patents, and comments from authority. Six advertisements were developed using these tools: "A": relevant image + explanation of ingredients + scientific diagram of efficacy; "B": relevant image + explanation of ingredients; "C": relevant image; "D": irrelevant image; "E": irrelevant image + explanation of ingredient + patent; "F": irrelevant image + explanation of ingredient + comments from authority. To analyze the consumer perceptions on HFFs and advertisement effects, 300 respondents were requested to answer a questionnaire comprising of the following questions: 5 questions of attitudes (necessity of HFFs, trust in HFFs, gathering information, watching advertisements and trust in advertisement claims) and 6 questions on the 6 developed advertisements (attention, understanding, sufficiency of information, sympathy, trust, and purchase). Scoring was done as per the 5 Likert scale. There was a higher proportion of females and the elderly, as compared to males and youngsters. The overall consumer attitudes were positive. Explanation of ingredients, scientific diagram of health benefit, patents and expert comments were helpful factors in increasing the advertisement evaluation by consumer, but the images were not. Advertisement evaluation of consumer did not differ with gender and age. However, differences were observed between some of the consumer attitudes (necessity of HFFs, trust in HFFs, gathering information and trust in advertisements claim) and advertisement evaluations (attention, understanding, sympathy and purchase). Our results indicate that for consumers utilizing the HFFs, advertisements with concrete tools such as diagrams, patent, and expert comments are more helpful. However, for consumers who do not have interest in HFFs, the scientific information was irrelevant. We believe that to maximize the effect of health information in advertisements, consumers should be segmented, and customized tools for each segment needs to be developed.

정책유형별 정책네트워크 분석 -"전통시장 시설현대화 사업"과 "대형마트 의무휴업제" 비교를 중심으로-

이연경 ( Yeon Kyeong Lee ) 한국정책학회 2015 韓國政策學會報 Vol.24 No.2

본 연구는 정책네트워크 모형의 주요 한계점인 ‘정책네트워크 구성요소 간 설명력이 부족’한 점과 ‘단일사례 연구만 주를 이루고 비교연구가 부족’한 점을 보완하고자 ‘정책유형별 정책네트워크 비교 분석’을 하였다. ‘전통시장 활성화’라는 동일한 정책 목표를 갖으나 정책 유형을 달리하는 ‘전통시장 시설현대화 사업’(배분정책)과 ‘대형마트 의무휴업제’(규제정책)를 정책네트워크 분석함으로써 두 정책유형 간 정책네트워크 양상에 차이를 발견하고, 어떤 차이점이 왜 발생하는지를 탐색하는 과정을 통해 정책네트워크 구성요소에 영향을 미치는 정책네트워크 결정요인을 논리적으로 추출하였다. 연구 결과 두 정책유형 간에는 정책네트워크의 양상이 달랐으며, 이는 근본적으로 정책과정에 참여하는 행위자의 ‘이해(관계)’와 ‘자원’에 기인함을 확인하였다. 이에 정책네트워크의 결정요인으로 행위자의 ‘이해(관계)’와 ‘자원’을 두고, 이를 중심으로 정책네트워크의 구성요소인 행위자(행위자 수), 상호작용(행위자 간 협력의 정도), 권력구조(행위자 간 자원배분 상태)가 어떻게 상호 간 논리적으로 관계 맺는지 이론적 틀을 제시하였다. This study attempted comparative analysis of the policy network by the type of policy to complement the main limitations of the policy network model. This paper focused on the following limitations of the policy network model: the lack of explanation for relationship among the policy network components and few comparative studies compared with many single case studies. Specifically, this study analyzed different policy types with the same policy objectives(vitalizing policy to traditional market). Two policy cases are ‘Traditional Market Modernization Project(distribution policy)’ and ‘Semimonthly Sunday Off System of Megamarket(regulation policy)’. Are there differences in appearance of policy network between the two policy types? What are the differences between those things? Why these differences occur between the types of policy? Through the search for these questions, the policy network determinants, deciding the policy network components, were logically extracted. As a result, this study identified that the policy network between the types of policy looked different. And this was due to fundamentally ‘interests’ and ‘resources’ of the actors involved in the policy process. So this paper put the ‘interests’ and ‘resources’ of actors as ‘the determinants of policy network’ and suggested a theoretical framework explaining how the components of policy network are connected to each other, based on these determinants of policy network. Namely this study explained that how these components of policy network (① actors : number of actors, ② interaction : the degree of cooperation among the actors, ③ power structures : states of the resource allocation among actors) are connected to each others.

트로트 오디션 프로그램을 통한 이슈 변화 고찰

이연경(Yeon Kyeong Lee),홍성규(Sung kyoo Hong) 한국문화융합학회 2023 문화와 융합 Vol.45 No.7

종설(綜說) : 오령산증(五령散證)오산증에 대한 복령감초탕(茯령甘草湯), 소청룡탕(小靑龍湯), 저령탕(저령湯), 문합산(文蛤散), 이중환(理中丸) 증(證)과의 비교고찰 -강평상한론(康平傷寒論) 원문 중심으로-

이연경 ( Yeon Kyeong Lee ),강석봉 ( Seok Bong Kang ) 대구한의대학교 제한동의학술원 2011 東西醫學 Vol.36 No.3

The goal of this study is to find out the original intention of Zhang Zhong-Jing(張仲景), the author of Shanghanlun(傷寒論), about Wuling-san(五령散). The text of Kangping-Shanghanlun(康平傷寒論), the oldest text among all handed down, was selected for that. The phrases on Wuling-san(五령散) were analyzed through careful comparison with 5 other medicinal herbs in Shanghanlun(傷寒論). In result, we conclude that Wuling-san(五령散) could be used for Taiyangxushui(太陽蓄水), which is a state of bladder losing urinary function. The main symptoms are thirst, urine imperfection, fever and vomiting after drinking water. Symptoms of Wuling-san(五령散) are distinct from those of Fulinggancao-tang(茯령甘草湯) which has not thist and urine imperfection. In clinical cases of Wuling-san(五령散), a surface of body is weak and sweat. On the contrary, Xiaoqinglong-tang(小靑龍湯)``s surface of body is dense, so no sweat. Symptoms of Wuling-san(五령散) and Zhuling-tang(저령湯) are very similar. However Wuling-san(五령散) belongs to Taiyangbing(太陽病) and Zhuling-tang(저령湯) to Yangmingbing(陽明病), Shaoyinbing(少陰病). There is no thirst symptom in Wenge-san(文蛤散)``s case. Since it``s not aimed at bladder urinary function. When xieqi(邪氣) invades deeper, then it can become the case of Wuling-san(五령散). In Lizhong-wan(理中丸)``s case, shuishi(水濕) is congested due to pixuhan(脾虛寒) so that it shows no thirst either.

골반결핵과 단측 난소절제의 병력이 있는 환자의 조기 폐경 후 갱년기 증상 치험 1례

이연경 ( Yeon Kyeong Lee ),유영기 ( Yung Ki Yoo ),이동녕 ( Dong Nyung Lee ),김형준 ( Hyung Jun Kim ) 대한한방부인과학회 2008 大韓韓方婦人科學會誌 Vol.21 No.3

귀비탕(歸脾湯)이 Estradiol Valerate로 유도된 흰쥐의 다낭성 난소에 미치는 영향

이연경 ( Yeon Kyeong Lee ),서일복 ( Il Bock Seo ),이동녕 ( Dong Nyung Lee ),김형준 ( Hyung Jun Kim ) 대한한방부인과학회 2008 大韓韓方婦人科學會誌 Vol.21 No.3

만성 골반염에 대한 치험 1예(例) 보고

이연경 ( Yeon Kyeong Lee ),남은정 ( Eun Jung Nam ),이동녕 ( Dong Nyung Lee ),김형준 ( Hyung Jun Kim ) 대한한방부인과학회 2007 大韓韓方婦人科學會誌 Vol.20 No.2