융합성 망상 유두종증의 임상 및 병리조직학적 , 전자현미경적 고찰

이승헌,김균태,이원수,안성구 ( Seung Hun Lee,Kyun Tae Kim,Won Soo Lee,Sung Ku Ahn ) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.6

지속성 이색성 홍반 25예의 임상적 연구

이승헌(Seung Hun Lee),한승경(Seung Kyung Hann),박윤기(Yoon Kee Park),이성낙(Sung Nack Lee) 대한피부과학회 1986 大韓皮膚科學會誌 Vol.24 No.6

We studied 25 cases of clinically diagnosed erythema dyschrornicum perstans (EDP) who were seen in our clinic within 11-year period, from 1975 through 1985, and compared light and electron microscopic findings, and direct immunoflunrescence findings. The results are summarized as follows: 1. There were 16 males(64%) and 9 females(36%). The peak age incidence was in the second decade. 2. The mean age of onset was 18 years(M: 16. 6, F: 19. 4) and the rnean duration was 1.8 years(M: 2.6, F: 1.0). 3. The annual incidence increased from 1981 and was peaked in 1985. 4. The most commonly involvement site was the trunk(92%), the least common involvement(4%) was one of the face, neck, and shoulder combined. 5. The histopathologic findings in most patients shows focal vacuolization of the basal cell layer, pigment incontinence, dermal melanophages. 6. Electron microscopic findings of five patients consist of vauoles with abundant melanosomes in the basal cells, widened intercellular spaces and dermal melanophages.

과학기술위성 2호 준비행모델 환경시험 결과

이승헌(Seung-Hun Lee),박종오(Jong-Oh Park),심은섭(Eun-Sup Sim),이승우(Seung-Woo Rhee),서정기(Jung-Ki Seo),장태성(Tae-Sung Jang),이상현(Sang-Hyun Lee),김성현(Sung-Hyun Kim) 한국항공우주연구원 2007 항공우주기술 Vol.6 No.1

과학기술위성 2호는 국내에서 최초로 개발되는 소형위성발사체(KSLV-1)에 의하여 국내 발사장(나로 우주센터)에서 발사될 위성이다. 2002년 개발을 시작하여 엔지니어링모델(EM), 준비행모델(PFM), 비행모델(FM)을 개발 완료하였다. 위성의 기능을 점검하기 위해 종합적인 전기/전자 기능시험과 우주환경시험, 발사환경시험을 수행한다. 본 논문은 성공적으로 수행한 과학기술위성 2호 준비행모델의 우주환경시험과 발사환경시험에 대한 분석과 그 결과를 보고한다. STSAT-2 (Science & Technology SATellite-2) is a Korea micro-satellite which will be launched at NARO Space center in Koheung, Korea. Launch vehicle for STSAT-2 is KSLV-1 (Korea Space Launch Vehicle-1) which is the first development in Korea space launch vehicle program. Starting development in 2002 EM(Engineering Model), PFM(Proto-Flight Model), and FM(Flight Model) were developed completely. Electrical functional test, space environmental test, and launch vehicle environmental test on system level are performed for testing those development models. In this paper we report the results of STSAT-2 PFM space environmental test and launch vehicle environmental test which is successfully completed.

최근 병원 내원 여드름 환자의 통계적 고찰

이승헌 ( Seung Hun Lee ),박태현 ( Tae Hyun Park ),강원형 ( Won Hyoung Kang ),황규광 ( Kyu Kwang Whang ),이창우 ( Chang Woo Lee ),성경제 ( Kyung Jeh Sung ),안성구 ( Sung Ku Ahn ),박장규 ( Jang Kyu Park ) 대한피부과학회 1996 대한피부과학회지 Vol.34 No.3

Background: Many patients with acne have little information about its cause, course, and treatment although it is one of the most common skin diseases seen at hospitals. Objective : We would like to find out what acne patients think about the etiology of acne, what factors affect its course their treatment methods before going to hospital, and the psychological impact of acne. Methods : We classified the clinical levels of acne patients who visited seven university hospitals for the first time. We distributed questionnaires to them and analysed the results statistically. Results : 1) Patients were classified,according to their level of clinical severity : mild type(45.0%), moderate type(46.2%), and seuere type(8.8%). 2) The mean age at onset was 15.7 in males and 16.7 in females. 3) 69.3% of patients experienced that psychological stress had aggravated acne. 4) 42.8% of patients experienced that certain foods had aggravated acne. 5) 66.8% of female patients experienced aggravation of acne after starting to wear make-up. 6) 25.1% of female patients complained of a flare-up 1-7 days premenstrually. Conclusion : Acne is affected by many different factors, but there seems to be an especially close relationship between acne and the psychological factors which influence social life. (Kor J Dermatol 1996;34(3): 386-393)

건선에 대한 경구용 Etretinate ( Ro 10 - 9359 ) 및 Vitamin E의 병용치료 효과

이성낙 ( Sung Nack Lee ),이정복 ( Jung Bock Lee ),조정구 ( Chung Koo Cho ),이해을 ( Hae Eul Lee ),김수찬 ( Soo Chan Kim ),김덕현 ( Duck Hyun Kim ),방동식 ( Dong Sik Bang ),이승헌 ( Seung Hun Lee ),박한성 ( Han Sung Park ),국홍일 ( 대한피부과학회 1984 大韓皮膚科學會誌 Vol.22 No.2

Etretinate(Ro 10-9359), an aromatic analogue of vitamin A acid, has been known to be effective in the treatment of psoriasis, Darier's disease, pityriasis rubra pilaris, ichthyosis, and palmoplantar keratoderma when administered orally. In this experiment, we compared the therapeutic and side effects between a group with high dose therapy(initially 75mg of etretinate a day) and an another group with low dose therapy(initially 40mg of etretinate a day). We also observed whether the pretreatment followed by combined treatment with vitamin E could potentiate the therapeutic effect as well as reduce the side effects of oral etretinate. This experiment comprised 102 moderate to severe psoriatic patients. The following results were obtained from this experiment. 1. Fifty-six among 92 patients(61%) who were treated with etretinate for more than 4 weeks showed good to excellent therapeutic effect. 2 The high dose therapy was more effective, but showed more side effects than low dose therapy. 3 Vitamin E did not potentiate the effect of etretinate. In low dose therapy, the pretreatment followed by combined treatment with vitamin E showed a tendency to reduce the side effects of etretinate.

Behcet 증후군의 분류아형과 현증상에 따른 백혈구 이동억제검사 성적

이은소(Eun So Lee),양동순(Dong Soon Yang),이승헌(Seung Hun Lee),방동식(Dong Sik Bang),이성낙(Sung Nack Lee),최인홍(In Hong Choi),이봉기(Bong Ki Lee),윤정구(Jung Koo Youn) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.6

This study was undertaken to investigate the immunological mechanism of Behqet s syndrome, considered to be important in the pathogenesis of the disease. Seventy- three patients with complete, incomplete and suspected types of Behget's syndrotne were tested for leukocyte migration ingibition factor(LIF), one of the lymphokines. The results were as follows : 1. There was no difference between the average LIF activity of all the patients and that of eontrol. 2. LIF activity of complete type, according to Shirnizus classification, was significaritly lower than the control value. 3. LIF activity of ocular type, according to Lehners classification, was signficantly lower than the control value. 4. LIF activity for patients with 4 clinical symptoms was well below the value for patients with less symptomes 5. For patients with single clinical symptom, LIF activity of complete type was well below the values of incomplete and suspected types. 6. In suspected and mucocutaneous types, LIF activity was low when the patients showed two clinical symptoms than one. Thus, LIF activity was low for patients with complete, ocular and neurological types and with multiple symptorns.

가변 저추력을 이용한 달탐사 임무궤도 설계

이승헌(Seung-Hun Lee),박종오(Jong-Oh Park),심은섭(Eun-Sup Sim),송영주(Young-joo Song),박상영(Sang-Yong Park) 한국항공우주연구원 2008 항공우주기술 Vol.7 No.1

제 2의 우주경쟁 시대를 맞이하여 세계 각국은 달을 선점하기 위한 치열한 경쟁을 벌이고 있다. 달에 영구기지를 2020년까지 건설하겠다는 미국을 비롯하여 유럽, 일본, 중국은 달탐사선을 성공적으로 발사하였으며 인도는 발사를 준비 중이다. 이와 같은 국제적인 분위기 속에 우리나라도 2020년까지 달에 탐사선을 보낼 계획을 발표하였다. 본 연구에서는 가변저추력을 이용한 달탐사 위성 설계에 기본 자료로 사용될 수 있는 달탐사 임무궤도를 설계하였으며, 이를 바탕으로 SMART-l과 비슷한 제원을 갖는 가상의 달탐사 임무를 설정하여 비행궤적을 산출하였다. Since the 1st space race between the United States and Soviet Union during the 1960s, we are competing 2nd space race to occupy the Lunar territory. Since the United States announced to construct the Lunar Base by the end of 2020, EU, Japan, and China launched Lunar explorers successfully. Even India is planning to launch a Lunar explorer in 2008. Korean government also announced that the Korea will launch first Lunar explorer in 2020. In this research Lunar mission trajectory design which will be fundamental data for Lunar mission with variable low thrust and Lunar mission trajectory which has a similar mission specification to SMART-1 are presented.

신혈관성 고혈압 진단과 Captopril 검사

이승헌(Seoung Hun Lee),윤형규(Hyung Gue Yoon),송윤상(Yoon Sang Song),최문영(Moon Young Choi),김석은(Seok Eun Kim),박인석(In Seok Park),장윤식(Yoon Sik Chang),방병기(Byung Kee Bang) 대한내과학회 1994 대한내과학회지 Vol.46 No.1

N/A Background: The Captopril test (Muller, 1986) appears to represent a simple and useful screening tool in the diagnosis of renovascular hypertension. The limitations of the sennsitivity, specificity have been reported under certain circumstances. We performed this study to evaluate the sensitivity, specificity and predictive value of the Captopril test in the diagnosis of renovascular hypertension. Methods: We calculated the sensitivity, specicity and predictive value of the Captopril test in 26patients with clinical suspicion of renovasculr hypertension. We performed the Captopril test and renal angiography in these patients. Results; 1) The Captopril test was positive in 8 patients (30.7%), in whom 26renovascular hypertension were suspected. 2) The mean value of basal and stimulated plasma renin activity were 4.55±1.74ng/ml/hr and 19.89±7.19ng/ml/hr respectively, in 8patients with positive Captopril test. The mean value of percent increase of stimulated PRA was 384±227.9% in these patients. 3) The mean value of basal and stimulated plasma renin activity were 7.27±5.29ng/hr and 8. 78±5.89ng/ ml/hr respectively, in patients with negative Captopril test. The mean value of percent increase of stimulated PRA was 34.61±30.56% in these patients. 4) In patients with postivie Captopril test, there were 4true positive (50%) and 4false positive (50%) by renal angiography. In 18patients with negative Captopril test, there was 1false negative who had abnormal angiography. 5) The sensitivity, specificity and predictive value of the Captopril test were 80%, 81% and 50% respectively. Conclusion: The Captopril test seems to have limitations of sensitivity, specificity and predictive value in the diagnosis of renovascular hypertension. The careful clinical clinical application of Captopril test and renal angiography should be considered in the diagnosis of renovascular hypertension.

건조피부

이승헌(Seung Hun Lee),장성남(Sung Nam Chang) 한국항공우주의학협회 1994 항공우주의학회지 Vol.4 No.1

Hydrometer와 Corneometer를 이용한 피부표면 수분상태의 비교측정

이승헌(Seung Hun Lee),정준(Joon Chung),안성구(Sung Ku Ahn),강진수(Jin Soo Kang),권오규(Oh Kyu Kwon) 대한피부과학회 1994 대한피부과학회지 Vol.32 No.4

Background : Hydration, the water content of the stratum corneum, is an important factor in both the appearance and the barrier function of the skin. Many non-invasive methods have been developed in order to assesa the hydration state of the skin and the effect of various moisturizers. The hydrometer and carneometer are commercially available instruments which are widely used in dermatologic research. Objective : Our purpose wa,s to compare the measuring usefulnes of both instruments on normal subjects with a wide range of hydration states of the hornylayer. Methods : We measured the conductance with the hydrometer and the capacitance with the corneometer in various hydrating eonditions and compared both insruments. Results : Conductance had a non linear correlation with capacita ice. Capacitance measured with the corneometer had a high sensitivity to moisture in a wide range of hydration levels. On the other hand, conductance guaged with the hydrometer showed a few sensitivity to moisture at a low level. When the hydretion level was measured after a moiturizer was added, 10 % urea cream showed a sharp increase by 256% in terms of conductanae, and H-base by 97.8%. Mineral oil decreased by 41.5% and petrolatum by 62% respectively. On the other hand, when measured in terms of capacitance under the same conditions as above, 38.9 increase in 10% urea cream, 19.3% increase in H-base, 20% decrease in mineral oil, and 43.5 % decrease in petrolatum were reported. Conductance showed a higher hygroscopicity and a lower water holding capacity than capacitance did. When the measurement of the moisture level iri virious parts of the human body is performed, the corneometer provided us with more stable alies than the hydrometer. While the hydrometer can not the available and appropriate under the condition of insulation, the corneometer can measure moisture levels even down at the depth of 250mm. When measured after the oily surface of the forehead was cleansed with soft tissue, conductance and capacitance revealed higher values of moisture levels than before the eleanin. However, there is no statistical significance in these values. Conclusion : The hydrometer is a more appropriate tool for the measurement of moisture at a high level, and the corneometer at a low moisture level. The hydrcmeter is a more sensitive method of measuring the increase and the decrease in the moisture level. (Kor J Dermatol 1994; 32(4): 599-608)