켈로이드와 비후성 반흔에서 냉동 외과술 후 스테로이드 병변내 주사의 병용 요법에 관한 임상적 분석

황규광,박혜진,명기범 ( Kyu Kwang Whang,Hae Jin Park,Ki Bum Myung ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.3

Background: Keloids and hypertrophic scars are benign fibrous growths which usually occur in predisposed individuals after trauma. Numerous modalities have been used to treat keloids and hypertrophic scars, but the final results have been so far unsatisfactory. Objective : The purpose of tlis study was to evaluate the effect of the combination of cryosurgery and intralesional corticoster oid for treatment of these scars. Method : Thirty patients, aged 17 to 45 years old, with keloids or hypertrophic scars(mean duration, 6.4 years) were treated using solid CO2 followed by intralesional injection of triamcinolone acetonide(13.3 mg/ml). Two freeze-thaw cycles per lesion were employed. Freezing time was chosen arbitrarily from 7 to 20 sec depending on the characteristics of each scar. Results . The results are summarized as follows. 1. Excellent and good results were achieved in 57% of all subjects on average, 77% of those who were treated more than 3 times, and 48% of those treated less than twice. 2. The keloid of less than 2 years duration showed better results than older ones. 3. No recurrence was seen in 63% of patients, but partial recurrence in 21% of patients and complete recurrence in 10% were observed. Lesions on the trunk showed less improvement(p<0. 05) and were more recurrent than other lesions. 4. There were complications in 9 patients, such as hyperpigmentation(6), hypopigmentation(1), infection(1) and telangiectasia(1). Conclusion : Cryosurgery and intralesional corticosteroid injections produced synergistic advantages. A cornbination of these modalities might be an effective treatment modality in keloids and hypertrophic scars. (Kor J Dermatol 1997;35(3): 450-457)

Mohs Micrographic Surgery에 의한 비부 기저 세포암의 제거 및 Nasalis Myocutaneous Sliding Flap복원

황규광(Kyu Kwang Whang),이융재(Yung Jae Lee) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.4

A technique for the chemical fixation of cutaneous tumors followed by serial excision using microscopic control has been developed since the mid 1930s. Mohs micrographic surgery is the most reliable and cost effective treatment modslity, offering maximal preservaticn of normal tissue and therefore the lowest functional and cosmetic morbidity in the cancer treatments. We report a case of basal cell carcinoma treated with Mohs micrographic surgery and reconstructed with nasalis myocutaneous sliding flap. The pstient was a 56-year-old woman, who had a been sized basal cell carcinoma on her nasal tip for the previous 3 years. The lesion was removed under complete microscopical control using fresh tissue technique. The defect healed with atrophic scar formation ore and half months later. To remove scar tissue and to gsin proper cosmetic results, reconstruction with nasalis myocutaneous sliding flap was performed successfully. (Kor J Dermatd 1993;31(4):586-599)

자가 지방 이식술과 진피내 콜라젠 주입을 이용한 안면위축의 교정

황규광(Kyu Kwang Whang),윤주호(Ju Ho Yoon) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.5

We present our experience with autologous fat injection and collager implantation in the treatment of facial atrophy. The surgical teclinigues are described for injecting the colagen into the nasolabial fold and collecting fat from the lower abdomen and then injecting the fat into the depressed site on the face. There were no serious complications without slowly progressive, volume reduction. We think that, these techniques could have a plae in the treatment of problems relatcd to facial depression. However, a longer follow-ups and more clinical experiences will be needed in order to reach some definite conclusions. (Kor J Dermatol 1993;31(5):823-828)

위축성 반흔에서 쌈지봉합술을 이용한 펀치상향술의 임상적용

황규광 ( Kyu Kwang Whang ),김현주 ( Hyun Joo Kim ) 대한피부과학회 1998 大韓皮膚科學會誌 Vol.36 No.2

Background: Punch grafts and punch elevation can be useful for the correction of deep pitting or round atrophic acne scars. The traditional punch elevation technique gives inadequete results. Even round scars leave a retraction space and do not always heal well. Objectives & Methods : To improve the cosmetic results of traditional punch elevation and thus promote the use of punch elevation instead of punch grafting, we performed punch elevation with purse-string sutures on 10 patients with acne, pox & atrophic scars. We performed dermabrasion or CO2 laserbrasion after 8 weks. Results : Nicely fit margins of the punch elevation site with purse-string suture left no retraction spaces and enhanced the aesthetic results. Conclusion : Punch elevation is a simple, satisfactory method of improving cosmetic results in scars. The Purse-string suture technique can make it a more valuable tool for surgery of facial scars, because it overcomes of disadvantages the punch elevation. (Korean J Dermatol 1998;36(2): 286-290)

VDRL 검사에 양성반응을 보인 환자 중 매독에 대한 치료경력과 증세가 없는 환자의 혈청에서 19 S ( IgM ) - FTA 검사 양성율

황규광(Kyu Kwang Whang),이민걸(Min Geol Lee),이정복(Jung Bock Lee) 대한피부과학회 1987 大韓皮膚科學會誌 Vol.25 No.3

On a total 233 sera from the VDRL reactive patients without a history of syphilitic symptoms or treatment for syphilis, TPHA and 19S(IgM)-FTA tests were performed, Also the reactivities of the 19 S (IgM)-FTA test in relation to the VDRL and the TPHA titers were observed. The results are summarized as follows: 1. Among 233 sera, 103 sera(44%) showed negative results in the 19S(IgM)- FTA test. 2. Reactivities of the 19 S(IgM)-FTA test were significantly increased in relation to the VDRL, titers arnong 233 sera reactive in the VDRL test: 47% in the VDRL titer 1: 1, 61% in 1: 2, 71% in 1: 4, 62% in 1: 8, 96% 1: 16 or more. 3. There was no relationship statistically (IgM)-FTA test and the TPHA titers. It can be derived from the above results that when a person with no history of treatment for syphilis and clear of any signs of syphilis shows a positive reaction in the VDRL test, he is less likey to be a syphilis patient when the VDRL titer is low.

오타모반에서 냉동외과술의 치료효과에 대한 임상평가

황규광 (Kyu Kwang Whang) 대한피부과학회 1996 大韓皮膚科學會誌 Vol.34 No.4

Background: Cryosurgical treatment for nevus of Ota could be effective and cheap, but has not been introduced too much in detail. Objective : This study was done to evaluate the clinical efficacy according to its determinants, and the complications of cryosurgery. Methods : 109 patients with nevus of Ota were treated with hard chalk dry ice which contacted the skin consistently of was rolled fast. Accessible patients were evaluated by phone or direct interview. Results : Satisfactions assessed by patients after cryosurgery were excellent 21%, moderate 51%, fair 17% and poor 11%, respectively. Satisfactions assessed by doctor were quite higher than those by patient. Satisfactions assessed by patients were affected by clinical determinants such as age over 40 and color of the lesion, but not by clinical type, number of sessions, and combinations with laser. Complications were in the following order : textural change, hypopigmentation, hypertrophic scar, persistent erythema, hyperpigmentation, infection and milia formation. Conclusion : Cryosurgery using dry ice for the treatment of nevus of Ota was quite effective but technical improvements for decreasing complications or combinations with Q switched laser and other surgical techniques might be required. (Kor J Dermatol 1996;34(4) : 585~590)

면역 계란을 이용한 Propionibacterium acnes에 대한 항체 제조와 특성 분석

황규광(Kyu Kwang Whang),최은선(Eun Sun Choi) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.9

N/A Background : Treatments inhibiting Propionibacterum acnes as like antibiotics for acne vulgaris can produce complications, and have their limited uses. Objective : Antibodies reacting to P. acnes were produced from immunized chicken eggs, and were characterized by aggulutination test and inhibiting abilities to growth of P. acnes. Methods : P. acnes were cultured, and their lipase were used as immunogen. Antibodies were purified from immunized chiken eggs by diafiltration. Their titers were measured by ELISA. Antigen-antibodies agglutination test was performed, and the ability of inhibitions of P. acnes grown in media was observed. Results : Antibodies were well produced especially when 0.25 to 2 mg of immunogen were injected per one chicken. When antibodies were reacting to P. acnes, pellet formations were not shown because of agglutination above 17.8 pg concentration of antibodies, and acitivities of P. acnes were markedly suppressed on microscopic examination. Growth of P. acnes on media were also inhibited for quite a long time. Conclusion : Antibodies reacting to P. acnes were produced, and their abilities to inhibit the growth of P. acnes were confirmed. In future, produced antibodies from immunized chicken eggs would be hoped to be a main component of medication or cosmetics for improving or preventing acne lesions.(Korean J Dermatol 1993;37(9) : 1231∼1238)

Proper Planning of Surgical Excision

황규광 ( Kyu Kwang Whang ) 대한피부과학회 2004 초록집 Vol.42 No.10

두피의 원형결손에서 일측성 선상 전진피판의 Pinch 변형 ( Peng 피판 ) 에 의한 복원 2예

최유원,황규광 ( Yoo Won Choi,Kyu Kwang Whang ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.5

Pinch modification of the linear advancement flap(Peng flap) is a hybrid of the transitional linear advancement flap and two bilateral rotation flaps. The advantages of this technique are a wider and shorter flap and an increase of the skin survival rate. This technique can be applied not only to the dorsum of the nose, but also to large defects of the scalp secondary to the surgical excision of benign or nalignant. lesions, scars, aplasia cutis and cicatricial alopecia. We pres ent, two cases of round defects on the scalp. The first case is an 8-year-old boy suffering from cicatricial alopecia on the right temporal area. The second case is a 12 year-old boy who had had nevus sebaceus on the right temporal area since birth. Pinch modification of the linear advancement flap can be erformed after excision without changing the direction of hairs. (Korean J Dermatol 1997;35(5): 1027-1030)

Mohs 미세도식 수술 및 쌈지봉합 복원술을 이용한 융기성 피부섬유육종의 치험

최유원,황규광,함정희,이정복,Yoo Won Choi,Kyu Kwang Whang,Jeong Hee Hahm,Jung Bock Lee 대한피부과학회 1995 대한피부과학회지 Vol.33 No.6

Dermatofibrosarcoma protuberans is an uncommon, locally aggressive fibroblastic tumor, characterized by infrequent metastasis and a marked tendency of local recurrence after excision. Histologically, it shows large uniformed spindle shaped cells arranged in a cartwheel or storiform pattern. We report a case of dermatoribrosarcoma protuberans on the lower abdomen of a man aged of thirty, treated with Mohs micrographic surgery and purse-string suture repair. (Kor J Dermatol 1995;33(6): 1108-1113)